CA2473586A1 - Treatment of sleep disorders using sleep target modulators - Google Patents
Treatment of sleep disorders using sleep target modulators Download PDFInfo
- Publication number
- CA2473586A1 CA2473586A1 CA002473586A CA2473586A CA2473586A1 CA 2473586 A1 CA2473586 A1 CA 2473586A1 CA 002473586 A CA002473586 A CA 002473586A CA 2473586 A CA2473586 A CA 2473586A CA 2473586 A1 CA2473586 A1 CA 2473586A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- group
- therapeutic compound
- therapeutic
- sleep
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34991202P | 2002-01-18 | 2002-01-18 | |
| US60/349,912 | 2002-01-18 | ||
| US35732002P | 2002-02-15 | 2002-02-15 | |
| US60/357,320 | 2002-02-15 | ||
| PCT/US2003/001845 WO2003068148A2 (en) | 2002-01-18 | 2003-01-21 | Treatment of sleep disorders using sleep target modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2473586A1 true CA2473586A1 (en) | 2003-08-21 |
Family
ID=27737408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002473586A Abandoned CA2473586A1 (en) | 2002-01-18 | 2003-01-21 | Treatment of sleep disorders using sleep target modulators |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20030232839A1 (https=) |
| EP (1) | EP1471913A2 (https=) |
| JP (1) | JP2005519073A (https=) |
| AU (1) | AU2003210598A1 (https=) |
| CA (1) | CA2473586A1 (https=) |
| WO (1) | WO2003068148A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY28538A1 (es) * | 2003-09-26 | 2005-04-29 | Vertex Pharma | Derivados de fenil-piperazina como moduladores de receptores muscarínicos |
| WO2005107700A2 (en) * | 2004-04-26 | 2005-11-17 | Immuneregen Biosciences, Inc. | Anti-aging effects of substance p |
| JP4613031B2 (ja) * | 2004-05-06 | 2011-01-12 | エスエス製薬株式会社 | 催眠剤組成物 |
| DK1940467T3 (da) * | 2005-09-09 | 2017-02-13 | Paladin Labs Inc | Lægemiddelsammensætning med langvarig frigivelse |
| CN101252932B (zh) * | 2005-09-09 | 2012-10-03 | 安吉利尼莱博法姆有限责任公司 | 用于一天给药一次的曲唑酮组合物 |
| CA2641821C (en) | 2006-02-16 | 2017-10-10 | Imthera Medical, Inc. | An rfid-based apparatus, system, and method for therapeutic treatment of a patient |
| US20110077200A1 (en) * | 2006-12-06 | 2011-03-31 | Somaxon Pharmaceuticals, Inc. | Combination therapy using low-dose doxepin for the improvement of sleep |
| CA2697826A1 (en) | 2007-10-09 | 2009-04-16 | Imthera Medical, Inc. | System and method for neural stimulation |
| EP2349139B1 (en) | 2008-10-09 | 2017-05-31 | Imthera Medical, Inc. | Stimulation of a hypoglossal nerve for controlling the position of a patient's tongue |
| ES2370147T5 (es) † | 2009-10-23 | 2019-03-06 | Gruppo Cimbali Spa | Máquina de café con regulación de presión de distribución y procedimiento relacionado con la misma |
| KR20120101650A (ko) | 2009-11-10 | 2012-09-14 | 임테라 메디칼, 인코포레이티드 | 환자 혀의 위치를 제어하기 위한 혀밑 신경 자극용 시스템 |
| US9532952B2 (en) | 2011-01-28 | 2017-01-03 | Physician's Seal, LLC | Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients |
| US8691275B2 (en) | 2011-01-28 | 2014-04-08 | Zx Pharma, Llc | Controlled-release melatonin compositions and related methods |
| AU2012214553B2 (en) | 2011-02-11 | 2015-07-09 | Sociétés des Produits Nestlé S.A. | Multiparticulate L-menthol formulations and related methods |
| US8808736B2 (en) | 2011-02-11 | 2014-08-19 | Zx Pharma, Llc | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
| US8911780B2 (en) | 2011-02-11 | 2014-12-16 | Zx Pharma, Llc | Multiparticulate L-menthol formulations and related methods |
| US20120315337A1 (en) * | 2011-06-07 | 2012-12-13 | Shah Syed | Multiparticulate 5-htp compositions and related methods |
| WO2013074390A1 (en) * | 2011-11-14 | 2013-05-23 | Merck Sharp & Dohme Corp. | Triazolopyridinone pde10 inhibitors |
| ES2706152T3 (es) | 2013-04-23 | 2019-03-27 | Zx Pharma Llc | Composición entérica de múltiples partículas revestida con subrevestimiento proteico |
| US10420756B2 (en) | 2015-03-26 | 2019-09-24 | Sen-Jam Pharmaceutical Llc. | Methods and compositions to inhibit symptoms associated with veisalgia |
| JP7345495B2 (ja) * | 2018-04-06 | 2023-09-15 | ビーエーエスエフ ソシエタス・ヨーロピア | アミンを合成する方法 |
| EP4615585A1 (en) * | 2022-11-11 | 2025-09-17 | Gilgamesh Pharmaceuticals, Inc. | Methods of using trazodone to reverse the effects of 5-ht2a receptor agonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5116852A (en) * | 1990-12-03 | 1992-05-26 | Bristol-Myers Squibb Co. | Treatment of sleep disorders |
-
2003
- 2003-01-21 CA CA002473586A patent/CA2473586A1/en not_active Abandoned
- 2003-01-21 US US10/349,164 patent/US20030232839A1/en not_active Abandoned
- 2003-01-21 WO PCT/US2003/001845 patent/WO2003068148A2/en not_active Ceased
- 2003-01-21 AU AU2003210598A patent/AU2003210598A1/en not_active Abandoned
- 2003-01-21 US US10/501,855 patent/US20060009465A1/en not_active Abandoned
- 2003-01-21 EP EP03739676A patent/EP1471913A2/en not_active Withdrawn
- 2003-01-21 JP JP2003567333A patent/JP2005519073A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003210598A2 (en) | 2003-09-04 |
| US20060009465A1 (en) | 2006-01-12 |
| US20030232839A1 (en) | 2003-12-18 |
| EP1471913A2 (en) | 2004-11-03 |
| AU2003210598A1 (en) | 2003-09-04 |
| JP2005519073A (ja) | 2005-06-30 |
| WO2003068148A3 (en) | 2004-04-01 |
| WO2003068148A2 (en) | 2003-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |