JP2005519073A - 睡眠標的モジュレーターを使用する睡眠障害の治療 - Google Patents

睡眠標的モジュレーターを使用する睡眠障害の治療 Download PDF

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Publication number
JP2005519073A
JP2005519073A JP2003567333A JP2003567333A JP2005519073A JP 2005519073 A JP2005519073 A JP 2005519073A JP 2003567333 A JP2003567333 A JP 2003567333A JP 2003567333 A JP2003567333 A JP 2003567333A JP 2005519073 A JP2005519073 A JP 2005519073A
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compound
group
therapeutic compound
therapeutic
sleep
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Japanese (ja)
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JP2005519073A5 (enExample
Inventor
デービッド ジー． ハンガウアー，
ハリー ジェファーソン レイトン，
デール エム． エドガー，
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ヒプニオン， インコーポレイテッド
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Publication of JP2005519073A publication Critical patent/JP2005519073A/ja
Publication of JP2005519073A5 publication Critical patent/JP2005519073A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003567333A 2002-01-18 2003-01-21 睡眠標的モジュレーターを使用する睡眠障害の治療 Withdrawn JP2005519073A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34991202P 2002-01-18 2002-01-18
US35732002P 2002-02-15 2002-02-15
PCT/US2003/001845 WO2003068148A2 (en) 2002-01-18 2003-01-21 Treatment of sleep disorders using sleep target modulators

Publications (2)

Publication Number Publication Date
JP2005519073A true JP2005519073A (ja) 2005-06-30
JP2005519073A5 JP2005519073A5 (enExample) 2005-12-22

Family

ID=27737408

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003567333A Withdrawn JP2005519073A (ja) 2002-01-18 2003-01-21 睡眠標的モジュレーターを使用する睡眠障害の治療

Country Status (6)

Country Link
US (2) US20060009465A1 (enExample)
EP (1) EP1471913A2 (enExample)
JP (1) JP2005519073A (enExample)
AU (1) AU2003210598A1 (enExample)
CA (1) CA2473586A1 (enExample)
WO (1) WO2003068148A2 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY28538A1 (es) * 2003-09-26 2005-04-29 Vertex Pharma Derivados de fenil-piperazina como moduladores de receptores muscarínicos
WO2005107688A1 (en) * 2004-04-26 2005-11-17 Immuneregen Biosciences, Inc. Inducing and maintaining hair color
JP4613031B2 (ja) * 2004-05-06 2011-01-12 エスエス製薬株式会社 催眠剤組成物
RU2008113439A (ru) * 2005-09-09 2009-10-20 Лабофарм Инк. (CA) Композиции с замедленным высвобождением лекарственного средства
CN101252932B (zh) * 2005-09-09 2012-10-03 安吉利尼莱博法姆有限责任公司 用于一天给药一次的曲唑酮组合物
AU2007217783A1 (en) 2006-02-16 2007-08-30 Imthera Medical, Inc. An RFID based apparatus, system, and method for therapeutic treatment of a patient
WO2008070795A2 (en) * 2006-12-06 2008-06-12 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
US20100198103A1 (en) 2007-10-09 2010-08-05 Imthera Medical, Inc. System and method for neural stimulation
AU2009302591B2 (en) 2008-10-09 2014-08-07 Imthera Medical, Inc. Method of stimulating a hypoglossal nerve for controlling the position of a patient's tongue
ES2370147T5 (es) † 2009-10-23 2019-03-06 Gruppo Cimbali Spa Máquina de café con regulación de presión de distribución y procedimiento relacionado con la misma
CA2780096A1 (en) 2009-11-10 2011-05-19 Imthera Medical, Inc. System for stimulating a hypoglossal nerve for controlling the position of a patient's tongue
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
WO2012103411A2 (en) 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
PL2672981T3 (pl) 2011-02-11 2018-09-28 Zx Pharma, Llc Wielocząstkowe preparaty l-mentolu i powiązane sposoby
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
US20120315337A1 (en) * 2011-06-07 2012-12-13 Shah Syed Multiparticulate 5-htp compositions and related methods
US9266881B2 (en) 2011-11-14 2016-02-23 Merck Sharp & Dohme Corp. Triazolopyridinone PDE10 inhibitors
KR101787225B1 (ko) 2013-04-23 2017-10-18 제트엑스 파마 엘엘씨 단백질성 서브코트를 갖는 장용 코팅된 다중 미립자 조성물
IL254641B2 (en) 2015-03-26 2024-01-01 Jacqueline M Iversen Methods and preparations including naproxen and fexofenamide for relieving symptoms of dizziness associated with alcohol consumption
US11390578B2 (en) * 2018-04-06 2022-07-19 Basf Se Method for synthesizing amines
WO2024102458A1 (en) * 2022-11-11 2024-05-16 Gilgamesh Pharmaceuticals, Inc. Methods of using trazodone to reverse the effects of 5-ht2a receptor agonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116852A (en) * 1990-12-03 1992-05-26 Bristol-Myers Squibb Co. Treatment of sleep disorders

Also Published As

Publication number Publication date
EP1471913A2 (en) 2004-11-03
US20060009465A1 (en) 2006-01-12
AU2003210598A1 (en) 2003-09-04
AU2003210598A2 (en) 2003-09-04
WO2003068148A3 (en) 2004-04-01
US20030232839A1 (en) 2003-12-18
CA2473586A1 (en) 2003-08-21
WO2003068148A2 (en) 2003-08-21

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