JP2005518789A5 - - Google Patents

Download PDF

Info

Publication number
JP2005518789A5
JP2005518789A5 JP2003564202A JP2003564202A JP2005518789A5 JP 2005518789 A5 JP2005518789 A5 JP 2005518789A5 JP 2003564202 A JP2003564202 A JP 2003564202A JP 2003564202 A JP2003564202 A JP 2003564202A JP 2005518789 A5 JP2005518789 A5 JP 2005518789A5
Authority
JP
Japan
Prior art keywords
antibody
psma
seq
region
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003564202A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005518789A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/002448 external-priority patent/WO2003064606A2/en
Publication of JP2005518789A publication Critical patent/JP2005518789A/ja
Publication of JP2005518789A5 publication Critical patent/JP2005518789A5/ja
Pending legal-status Critical Current

Links

Images

JP2003564202A 2002-01-28 2003-01-28 前立腺特異性膜抗原(psma)に対するヒトモノクローナル抗体 Pending JP2005518789A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5998902A 2002-01-28 2002-01-28
PCT/US2003/002448 WO2003064606A2 (en) 2002-01-28 2003-01-28 Human monoclonal antibodies to prostate specific membrane antigen (psma)

Publications (2)

Publication Number Publication Date
JP2005518789A JP2005518789A (ja) 2005-06-30
JP2005518789A5 true JP2005518789A5 (xx) 2006-03-02

Family

ID=27658271

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003564202A Pending JP2005518789A (ja) 2002-01-28 2003-01-28 前立腺特異性膜抗原(psma)に対するヒトモノクローナル抗体

Country Status (10)

Country Link
EP (1) EP1519747A4 (xx)
JP (1) JP2005518789A (xx)
KR (1) KR20040077889A (xx)
CN (1) CN1652821A (xx)
AU (1) AU2003224604B2 (xx)
BR (1) BR0307216A (xx)
CA (1) CA2474616A1 (xx)
MX (1) MXPA04007262A (xx)
NZ (1) NZ534687A (xx)
WO (1) WO2003064606A2 (xx)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7105159B1 (en) 1992-11-05 2006-09-12 Sloan-Kettering Institute For Cancer Research Antibodies to prostate-specific membrane antigen
US6569432B1 (en) 1995-02-24 2003-05-27 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen and uses thereof
US7381407B1 (en) 1996-03-25 2008-06-03 Medarex, Inc. Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
US6962981B1 (en) 1996-03-25 2005-11-08 Medarex, Inc. Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
US20050215472A1 (en) 2001-10-23 2005-09-29 Psma Development Company, Llc PSMA formulations and uses thereof
JP5355839B2 (ja) 2001-10-23 2013-11-27 ピーエスエムエー デベロプメント カンパニー, エル.エル.シー. Psma抗体およびタンパク質マルチマー
JP4942487B2 (ja) * 2003-12-10 2012-05-30 メダレックス インコーポレーティッド Ip−10抗体およびその用途
PL1766093T3 (pl) * 2004-02-06 2011-11-30 Univ Massachusetts Przeciwciała przeciw toksynom Clostridium difficile i ich zastosowania
US7598350B2 (en) * 2004-03-19 2009-10-06 Imclone Llc Human anti-epidermal growth factor receptor antibody
ES2403055T3 (es) * 2004-04-13 2013-05-13 F. Hoffmann-La Roche Ag Anticuerpos anti-P-selectina
EP2287195B1 (en) 2004-07-01 2019-05-15 Novo Nordisk A/S Pan-kir2dl nk-receptor antibodies and their use in diagnostik and therapy
PT1836225E (pt) 2005-01-06 2012-01-10 Novo Nordisk As Agentes de ligação a kir e métodos de utilização dos mesmos
ES2386366T3 (es) * 2005-02-18 2012-08-17 Medarex, Inc. Anticuerpo monoclonal humano contra el antígeno de membrana específico de la próstata (PSMA)
EP1851251A2 (en) 2005-02-18 2007-11-07 Medarex, Inc. Monoclonal antibodies against prostate specific membrane antigen (psma) lacking in fucosyl residues
CN101213297B (zh) * 2005-05-09 2013-02-13 小野药品工业株式会社 程序性死亡-1(pd-1)的人单克隆抗体及单独使用或与其它免疫治疗剂联合使用抗pd-1抗体来治疗癌症的方法
EP1726650A1 (en) * 2005-05-27 2006-11-29 Universitätsklinikum Freiburg Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
WO2007106869A1 (en) * 2006-03-14 2007-09-20 Cancer Targeted Technology Llc Peptidomimetic inhibitors of psma,compounds comprising them, and methods of use
US8852630B2 (en) 2008-05-13 2014-10-07 Yale University Chimeric small molecules for the recruitment of antibodies to cancer cells
EP2727606A3 (en) 2008-09-08 2015-09-23 Psma Development Company, L.L.C. Compounds for killing psma-expressing, taxane-resistant cancer cells
CA2738565C (en) * 2008-10-01 2023-10-10 Micromet Ag Cross-species-specific psmaxcd3 bispecific single chain antibody
CN101891818B (zh) * 2009-01-16 2012-07-25 中国人民解放军第四军医大学 抗人前列腺特异性膜抗原胞外区单链抗体及其应用
EP2419451A4 (en) * 2009-04-14 2012-11-14 Proscan Rx Pharma Inc ANTIBODIES DIRECTED AGAINST THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN
EP3138581B1 (en) 2011-03-17 2019-01-02 The University of Birmingham Re-directed immunotherapy
US20140161800A1 (en) 2011-04-22 2014-06-12 John W. Blankenship Prostate-Specific Membrane Antigen Binding Proteins and Related Compositions and Methods
PL2766048T3 (pl) 2012-10-12 2015-05-29 Medimmune Ltd Pirolobenzodiazepiny i ich koniugaty
US20160031887A1 (en) 2013-03-13 2016-02-04 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
CN103333249A (zh) * 2013-06-14 2013-10-02 广州康合生物科技有限公司 一种抗前列腺特异性膜抗原(psma)的单克隆抗体及其应用
EP3193940A1 (en) 2014-09-10 2017-07-26 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
AR104484A1 (es) * 2015-03-10 2017-07-26 Sorrento Therapeutics Inc Anticuerpos anti-psma como agentes terapéuticos
IL274151B (en) 2015-05-21 2022-07-01 Harpoon Therapeutics Inc Trispecific binding proteins and methods of use
MY197562A (en) 2015-09-21 2023-06-23 Aptevo Res & Development Llc Cd3 binding polypeptides
KR101704379B1 (ko) * 2015-10-27 2017-02-08 (주)알테오젠 항체-약물 접합체 및 그 제조방법
KR20210019491A (ko) * 2016-03-23 2021-02-22 서울대학교산학협력단 중증열성혈소판감소증후군 바이러스의 외막 당단백질에 결합하는 항체 및 이의 용도
JP7101621B2 (ja) 2016-05-20 2022-07-15 ハープーン セラピューティクス,インク. 単一ドメイン血清アルブミン結合タンパク質
MX2018014227A (es) 2016-05-20 2019-08-22 Harpoon Therapeutics Inc Proteinas de union de cadena unica de fragmento variable cd3.
US11623958B2 (en) 2016-05-20 2023-04-11 Harpoon Therapeutics, Inc. Single chain variable fragment CD3 binding proteins
CN109862919A (zh) 2016-10-11 2019-06-07 免疫医疗有限公司 抗体-药物缀合物联合免疫介导的治疗剂
KR20190087539A (ko) 2016-11-23 2019-07-24 하푼 테라퓨틱스, 인크. Psma 표적화 삼중특이성 단백질 및 사용 방법
EA201991168A1 (ru) 2016-11-23 2019-12-30 Харпун Терапьютикс, Инк. Белок, связывающий простатический специфический мембранный антиген
US11535668B2 (en) 2017-02-28 2022-12-27 Harpoon Therapeutics, Inc. Inducible monovalent antigen binding protein
BR112019023855B1 (pt) 2017-05-12 2021-11-30 Harpoon Therapeutics, Inc Proteínas de ligação à mesotelina
CN115028727A (zh) 2017-05-12 2022-09-09 哈普恩治疗公司 靶向msln的三特异性蛋白质及使用方法
AU2018346955A1 (en) 2017-10-13 2020-04-30 Harpoon Therapeutics, Inc. B cell maturation antigen binding proteins
CN111630070A (zh) 2017-10-13 2020-09-04 哈普恩治疗公司 三特异性蛋白质及使用方法
CN113286616A (zh) 2018-05-23 2021-08-20 Adc治疗有限公司 分子佐剂
CA3114038A1 (en) 2018-09-25 2020-04-02 Harpoon Therapeutics, Inc. Dll3 binding proteins and methods of use
EP3897851A2 (en) 2018-12-17 2021-10-27 Revitope Limited Twin immune cell engager
TW202132353A (zh) * 2020-02-18 2021-09-01 大陸商和鉑醫藥(上海)有限責任公司 一種分離的結合抗原psma的蛋白及其用途
CA3170833A1 (en) 2020-02-21 2021-08-26 Harpoon Therapeutics, Inc. Flt3 binding proteins and methods of use
WO2022079211A1 (en) 2020-10-16 2022-04-21 Adc Therapeutics Sa Glycoconjugates
GB202102396D0 (en) 2021-02-19 2021-04-07 Adc Therapeutics Sa Molecular adjuvant
US20230201366A1 (en) 2021-11-19 2023-06-29 Adc Therapeutics Sa Anti-psma conjugates
WO2024118940A1 (en) * 2022-12-01 2024-06-06 Twist Bioscience Corporation Anti-psma antibodies and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE198490T1 (de) * 1993-06-09 2001-01-15 Unilever Nv Verfahren zur herstellung von fusionsproteinen, die scfv fragmente enthalten, in transformierten schimmelpilzen
US7563874B2 (en) * 1998-08-31 2009-07-21 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
DK1210374T3 (da) * 1999-07-29 2007-02-19 Medarex Inc Humane, monoklonale antistoffer over for prostataspecifikt membranantigen
GB0001448D0 (en) * 2000-01-21 2000-03-08 Novartis Ag Organic compounds
EP2281843B1 (en) * 2000-06-16 2016-10-12 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to BLyS
JP5355839B2 (ja) * 2001-10-23 2013-11-27 ピーエスエムエー デベロプメント カンパニー, エル.エル.シー. Psma抗体およびタンパク質マルチマー
WO2004020588A2 (en) * 2002-08-30 2004-03-11 Biorexis Pharmaceutical Corporation Transferrin fusion protein libraries
AU2003298799A1 (en) * 2002-12-02 2004-06-23 Abgenix, Inc. Antibodies directed to phospholipase a2 and uses thereof

Similar Documents

Publication Publication Date Title
JP2005518789A5 (xx)
JP7412521B2 (ja) Cd47に対するヒト化及びキメラモノクローナル抗体
BR112021010402A2 (pt) Anticorpos biespecíficos anti-pd-l1/anti-4-1bb e uso dos mesmos
JP2018521691A (ja) 増殖性および炎症性疾患の処置における抗TfR抗体およびその使用
KR20200070324A (ko) 항-cd71 활성화 가능한 항체 약물 접합체 및 이의 사용 방법
WO2021197359A1 (zh) 一种构建多特异性抗体的平台
CN109721656B (zh) 靶向rankl的治疗性抗体
US20210284715A1 (en) Coagulation factor viii mimetic protein and uses thereof
JP7357012B2 (ja) 抗bcma car抗体、コンジュゲート、および使用方法
JP2023506262A (ja) 抗bcma car抗体、コンジュゲートおよび使用方法
JP2021518748A (ja) カルシトニン遺伝子関連ペプチド(cgrp)アンタゴニスト抗体
US10584175B2 (en) FN14-binding proteins and uses thereof
CN111108120A (zh) 抗人类血管内皮生长因子受体的抗体及其应用
CN111742220A (zh) 检测癌症患者中的肿瘤抗原的诊断性测定法
CN113166264B (zh) 一种分离的抗原结合蛋白及其用途
WO2023207475A1 (zh) 靶向gpc3的单克隆抗体和包含此抗体的抗体药物缀合物
CN115850458A (zh) 一种抗冠状病毒rbd蛋白的抗体、制备方法和应用
CA3227486A1 (en) Deimmunized vnar domains and scaffolds
JP2022540904A (ja) ヒトtrem-1に対する抗体およびその使用
WO2017125601A1 (en) Anti-bsep-specific antibodies