JP2005518789A5 - - Google Patents
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- JP2005518789A5 JP2005518789A5 JP2003564202A JP2003564202A JP2005518789A5 JP 2005518789 A5 JP2005518789 A5 JP 2005518789A5 JP 2003564202 A JP2003564202 A JP 2003564202A JP 2003564202 A JP2003564202 A JP 2003564202A JP 2005518789 A5 JP2005518789 A5 JP 2005518789A5
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- Prior art keywords
- antibody
- psma
- seq
- region
- amino acid
- Prior art date
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Images
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5998902A | 2002-01-28 | 2002-01-28 | |
PCT/US2003/002448 WO2003064606A2 (en) | 2002-01-28 | 2003-01-28 | Human monoclonal antibodies to prostate specific membrane antigen (psma) |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005518789A JP2005518789A (ja) | 2005-06-30 |
JP2005518789A5 true JP2005518789A5 (xx) | 2006-03-02 |
Family
ID=27658271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003564202A Pending JP2005518789A (ja) | 2002-01-28 | 2003-01-28 | 前立腺特異性膜抗原(psma)に対するヒトモノクローナル抗体 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1519747A4 (xx) |
JP (1) | JP2005518789A (xx) |
KR (1) | KR20040077889A (xx) |
CN (1) | CN1652821A (xx) |
AU (1) | AU2003224604B2 (xx) |
BR (1) | BR0307216A (xx) |
CA (1) | CA2474616A1 (xx) |
MX (1) | MXPA04007262A (xx) |
NZ (1) | NZ534687A (xx) |
WO (1) | WO2003064606A2 (xx) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105159B1 (en) | 1992-11-05 | 2006-09-12 | Sloan-Kettering Institute For Cancer Research | Antibodies to prostate-specific membrane antigen |
US6569432B1 (en) | 1995-02-24 | 2003-05-27 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
US7381407B1 (en) | 1996-03-25 | 2008-06-03 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US6962981B1 (en) | 1996-03-25 | 2005-11-08 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
JP5355839B2 (ja) | 2001-10-23 | 2013-11-27 | ピーエスエムエー デベロプメント カンパニー, エル.エル.シー. | Psma抗体およびタンパク質マルチマー |
JP4942487B2 (ja) * | 2003-12-10 | 2012-05-30 | メダレックス インコーポレーティッド | Ip−10抗体およびその用途 |
PL1766093T3 (pl) * | 2004-02-06 | 2011-11-30 | Univ Massachusetts | Przeciwciała przeciw toksynom Clostridium difficile i ich zastosowania |
US7598350B2 (en) * | 2004-03-19 | 2009-10-06 | Imclone Llc | Human anti-epidermal growth factor receptor antibody |
ES2403055T3 (es) * | 2004-04-13 | 2013-05-13 | F. Hoffmann-La Roche Ag | Anticuerpos anti-P-selectina |
EP2287195B1 (en) | 2004-07-01 | 2019-05-15 | Novo Nordisk A/S | Pan-kir2dl nk-receptor antibodies and their use in diagnostik and therapy |
PT1836225E (pt) | 2005-01-06 | 2012-01-10 | Novo Nordisk As | Agentes de ligação a kir e métodos de utilização dos mesmos |
ES2386366T3 (es) * | 2005-02-18 | 2012-08-17 | Medarex, Inc. | Anticuerpo monoclonal humano contra el antígeno de membrana específico de la próstata (PSMA) |
EP1851251A2 (en) | 2005-02-18 | 2007-11-07 | Medarex, Inc. | Monoclonal antibodies against prostate specific membrane antigen (psma) lacking in fucosyl residues |
CN101213297B (zh) * | 2005-05-09 | 2013-02-13 | 小野药品工业株式会社 | 程序性死亡-1(pd-1)的人单克隆抗体及单独使用或与其它免疫治疗剂联合使用抗pd-1抗体来治疗癌症的方法 |
EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
WO2007106869A1 (en) * | 2006-03-14 | 2007-09-20 | Cancer Targeted Technology Llc | Peptidomimetic inhibitors of psma,compounds comprising them, and methods of use |
US8852630B2 (en) | 2008-05-13 | 2014-10-07 | Yale University | Chimeric small molecules for the recruitment of antibodies to cancer cells |
EP2727606A3 (en) | 2008-09-08 | 2015-09-23 | Psma Development Company, L.L.C. | Compounds for killing psma-expressing, taxane-resistant cancer cells |
CA2738565C (en) * | 2008-10-01 | 2023-10-10 | Micromet Ag | Cross-species-specific psmaxcd3 bispecific single chain antibody |
CN101891818B (zh) * | 2009-01-16 | 2012-07-25 | 中国人民解放军第四军医大学 | 抗人前列腺特异性膜抗原胞外区单链抗体及其应用 |
EP2419451A4 (en) * | 2009-04-14 | 2012-11-14 | Proscan Rx Pharma Inc | ANTIBODIES DIRECTED AGAINST THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN |
EP3138581B1 (en) | 2011-03-17 | 2019-01-02 | The University of Birmingham | Re-directed immunotherapy |
US20140161800A1 (en) | 2011-04-22 | 2014-06-12 | John W. Blankenship | Prostate-Specific Membrane Antigen Binding Proteins and Related Compositions and Methods |
PL2766048T3 (pl) | 2012-10-12 | 2015-05-29 | Medimmune Ltd | Pirolobenzodiazepiny i ich koniugaty |
US20160031887A1 (en) | 2013-03-13 | 2016-02-04 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
CN103333249A (zh) * | 2013-06-14 | 2013-10-02 | 广州康合生物科技有限公司 | 一种抗前列腺特异性膜抗原(psma)的单克隆抗体及其应用 |
EP3193940A1 (en) | 2014-09-10 | 2017-07-26 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
AR104484A1 (es) * | 2015-03-10 | 2017-07-26 | Sorrento Therapeutics Inc | Anticuerpos anti-psma como agentes terapéuticos |
IL274151B (en) | 2015-05-21 | 2022-07-01 | Harpoon Therapeutics Inc | Trispecific binding proteins and methods of use |
MY197562A (en) | 2015-09-21 | 2023-06-23 | Aptevo Res & Development Llc | Cd3 binding polypeptides |
KR101704379B1 (ko) * | 2015-10-27 | 2017-02-08 | (주)알테오젠 | 항체-약물 접합체 및 그 제조방법 |
KR20210019491A (ko) * | 2016-03-23 | 2021-02-22 | 서울대학교산학협력단 | 중증열성혈소판감소증후군 바이러스의 외막 당단백질에 결합하는 항체 및 이의 용도 |
JP7101621B2 (ja) | 2016-05-20 | 2022-07-15 | ハープーン セラピューティクス,インク. | 単一ドメイン血清アルブミン結合タンパク質 |
MX2018014227A (es) | 2016-05-20 | 2019-08-22 | Harpoon Therapeutics Inc | Proteinas de union de cadena unica de fragmento variable cd3. |
US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
CN109862919A (zh) | 2016-10-11 | 2019-06-07 | 免疫医疗有限公司 | 抗体-药物缀合物联合免疫介导的治疗剂 |
KR20190087539A (ko) | 2016-11-23 | 2019-07-24 | 하푼 테라퓨틱스, 인크. | Psma 표적화 삼중특이성 단백질 및 사용 방법 |
EA201991168A1 (ru) | 2016-11-23 | 2019-12-30 | Харпун Терапьютикс, Инк. | Белок, связывающий простатический специфический мембранный антиген |
US11535668B2 (en) | 2017-02-28 | 2022-12-27 | Harpoon Therapeutics, Inc. | Inducible monovalent antigen binding protein |
BR112019023855B1 (pt) | 2017-05-12 | 2021-11-30 | Harpoon Therapeutics, Inc | Proteínas de ligação à mesotelina |
CN115028727A (zh) | 2017-05-12 | 2022-09-09 | 哈普恩治疗公司 | 靶向msln的三特异性蛋白质及使用方法 |
AU2018346955A1 (en) | 2017-10-13 | 2020-04-30 | Harpoon Therapeutics, Inc. | B cell maturation antigen binding proteins |
CN111630070A (zh) | 2017-10-13 | 2020-09-04 | 哈普恩治疗公司 | 三特异性蛋白质及使用方法 |
CN113286616A (zh) | 2018-05-23 | 2021-08-20 | Adc治疗有限公司 | 分子佐剂 |
CA3114038A1 (en) | 2018-09-25 | 2020-04-02 | Harpoon Therapeutics, Inc. | Dll3 binding proteins and methods of use |
EP3897851A2 (en) | 2018-12-17 | 2021-10-27 | Revitope Limited | Twin immune cell engager |
TW202132353A (zh) * | 2020-02-18 | 2021-09-01 | 大陸商和鉑醫藥(上海)有限責任公司 | 一種分離的結合抗原psma的蛋白及其用途 |
CA3170833A1 (en) | 2020-02-21 | 2021-08-26 | Harpoon Therapeutics, Inc. | Flt3 binding proteins and methods of use |
WO2022079211A1 (en) | 2020-10-16 | 2022-04-21 | Adc Therapeutics Sa | Glycoconjugates |
GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
US20230201366A1 (en) | 2021-11-19 | 2023-06-29 | Adc Therapeutics Sa | Anti-psma conjugates |
WO2024118940A1 (en) * | 2022-12-01 | 2024-06-06 | Twist Bioscience Corporation | Anti-psma antibodies and uses thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE198490T1 (de) * | 1993-06-09 | 2001-01-15 | Unilever Nv | Verfahren zur herstellung von fusionsproteinen, die scfv fragmente enthalten, in transformierten schimmelpilzen |
US7563874B2 (en) * | 1998-08-31 | 2009-07-21 | The Regents Of The University Of California | Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins |
DK1210374T3 (da) * | 1999-07-29 | 2007-02-19 | Medarex Inc | Humane, monoklonale antistoffer over for prostataspecifikt membranantigen |
GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
EP2281843B1 (en) * | 2000-06-16 | 2016-10-12 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to BLyS |
JP5355839B2 (ja) * | 2001-10-23 | 2013-11-27 | ピーエスエムエー デベロプメント カンパニー, エル.エル.シー. | Psma抗体およびタンパク質マルチマー |
WO2004020588A2 (en) * | 2002-08-30 | 2004-03-11 | Biorexis Pharmaceutical Corporation | Transferrin fusion protein libraries |
AU2003298799A1 (en) * | 2002-12-02 | 2004-06-23 | Abgenix, Inc. | Antibodies directed to phospholipase a2 and uses thereof |
-
2003
- 2003-01-28 CN CNA038073714A patent/CN1652821A/zh active Pending
- 2003-01-28 CA CA002474616A patent/CA2474616A1/en not_active Abandoned
- 2003-01-28 WO PCT/US2003/002448 patent/WO2003064606A2/en active IP Right Grant
- 2003-01-28 BR BR0307216-9A patent/BR0307216A/pt not_active IP Right Cessation
- 2003-01-28 EP EP03721280A patent/EP1519747A4/en not_active Withdrawn
- 2003-01-28 NZ NZ534687A patent/NZ534687A/en unknown
- 2003-01-28 MX MXPA04007262A patent/MXPA04007262A/es unknown
- 2003-01-28 KR KR10-2004-7011643A patent/KR20040077889A/ko not_active Application Discontinuation
- 2003-01-28 JP JP2003564202A patent/JP2005518789A/ja active Pending
- 2003-01-28 AU AU2003224604A patent/AU2003224604B2/en not_active Ceased
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