JP2005517647A5 - - Google Patents
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- Publication number
- JP2005517647A5 JP2005517647A5 JP2003550773A JP2003550773A JP2005517647A5 JP 2005517647 A5 JP2005517647 A5 JP 2005517647A5 JP 2003550773 A JP2003550773 A JP 2003550773A JP 2003550773 A JP2003550773 A JP 2003550773A JP 2005517647 A5 JP2005517647 A5 JP 2005517647A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- schizophrenia
- norepinephrine reuptake
- selective norepinephrine
- antipsychotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 201000000980 schizophrenia Diseases 0.000 claims 8
- 239000002767 noradrenalin uptake inhibitor Substances 0.000 claims 7
- VHGCDTVCOLNTBX-QGZVFWFLSA-N atomoxetine Chemical group O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=CC=C1C VHGCDTVCOLNTBX-QGZVFWFLSA-N 0.000 claims 5
- 229960002430 atomoxetine Drugs 0.000 claims 5
- 230000000561 anti-psychotic effect Effects 0.000 claims 3
- 208000027534 Emotional disease Diseases 0.000 claims 2
- 208000028017 Psychotic disease Diseases 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000003693 atypical antipsychotic agent Substances 0.000 claims 2
- 229940127236 atypical antipsychotics Drugs 0.000 claims 2
- 230000007278 cognition impairment Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 230000000698 schizophrenic effect Effects 0.000 claims 2
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical class N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 1
- 208000028698 Cognitive impairment Diseases 0.000 claims 1
- 206010010305 Confusional state Diseases 0.000 claims 1
- 206010012289 Dementia Diseases 0.000 claims 1
- 208000001495 Disorganized Schizophrenia Diseases 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 206010026749 Mania Diseases 0.000 claims 1
- 239000000164 antipsychotic agent Substances 0.000 claims 1
- 208000010877 cognitive disease Diseases 0.000 claims 1
- 230000001149 cognitive effect Effects 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 229960005017 olanzapine Drugs 0.000 claims 1
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 claims 1
- 208000020016 psychiatric disease Diseases 0.000 claims 1
- CBQGYUDMJHNJBX-RTBURBONSA-N reboxetine Chemical compound CCOC1=CC=CC=C1O[C@H](C=1C=CC=CC=1)[C@@H]1OCCNC1 CBQGYUDMJHNJBX-RTBURBONSA-N 0.000 claims 1
- 229960003770 reboxetine Drugs 0.000 claims 1
- 0 *c(cccc1)c1OC(CCN*)c1ccccc1 Chemical compound *c(cccc1)c1OC(CCN*)c1ccccc1 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33917401P | 2001-12-11 | 2001-12-11 | |
| PCT/US2002/036132 WO2003049724A1 (en) | 2001-12-11 | 2002-11-27 | Use of norepinephrine reuptake inhibitors for the treatment of cognitive failure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005517647A JP2005517647A (ja) | 2005-06-16 |
| JP2005517647A5 true JP2005517647A5 (https=) | 2006-01-26 |
Family
ID=23327833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003550773A Pending JP2005517647A (ja) | 2001-12-11 | 2002-11-27 | ノルエピネフリン再取り込み阻害物質の認知不全処置への使用 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20050009925A1 (https=) |
| EP (1) | EP1458368B1 (https=) |
| JP (1) | JP2005517647A (https=) |
| KR (1) | KR20040066895A (https=) |
| CN (1) | CN1713900A (https=) |
| AU (1) | AU2002352625A1 (https=) |
| BR (1) | BR0213581A (https=) |
| CA (1) | CA2467802A1 (https=) |
| CO (1) | CO5590907A2 (https=) |
| CZ (1) | CZ2004709A3 (https=) |
| DE (1) | DE60223718T2 (https=) |
| EA (1) | EA200400793A1 (https=) |
| EC (1) | ECSP045145A (https=) |
| ES (1) | ES2295435T3 (https=) |
| HR (1) | HRPK20040528B3 (https=) |
| HU (1) | HUP0402619A3 (https=) |
| IL (1) | IL161989A0 (https=) |
| MX (1) | MXPA04005716A (https=) |
| MY (1) | MY136367A (https=) |
| NO (1) | NO20042904L (https=) |
| NZ (1) | NZ532065A (https=) |
| PL (1) | PL369311A1 (https=) |
| SK (1) | SK2442004A3 (https=) |
| TW (1) | TW200300672A (https=) |
| WO (1) | WO2003049724A1 (https=) |
| ZA (1) | ZA200404274B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050049476A (ko) * | 2002-08-14 | 2005-05-25 | 파마시아 앤드 업존 캄파니 엘엘씨 | 홍조를 치료하기 위한 레복세틴의 용도 |
| ATE526954T1 (de) * | 2003-07-28 | 2011-10-15 | Leslie Joe Dunaway | Atomoxetin zur behandlung von allergischer rhinitis und asthma |
| CA2530014A1 (en) * | 2003-08-27 | 2005-03-10 | Eli Lilly And Company | Treatment of learning disabilities and motor skills disorder with norepinephrine reuptake inhibitors |
| KR20060121178A (ko) * | 2003-12-12 | 2006-11-28 | 일라이 릴리 앤드 캄파니 | 일과성 전신 열감, 충동 조절 장애 및 일반적인 의학상태로 인한 인격 변화 치료용 선택적 노르에피네프린재흡수 억제제 |
| JP4185154B2 (ja) * | 2004-04-30 | 2008-11-26 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 中枢神経系障害治療用の置換モルホリン化合物 |
| US7439399B2 (en) * | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals | Processes for the preparation of atomoxetine hydrochloride |
| US8580776B2 (en) * | 2007-07-10 | 2013-11-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating neurodegenerating diseases |
| US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
| US20100317731A1 (en) * | 2009-06-12 | 2010-12-16 | Shaya Elias K | Hyperhidrosis treatment |
| TW201107485A (en) * | 2009-07-31 | 2011-03-01 | Univ Nat Taiwan | Treating negative symptoms of schizophrenia associated with defective neuregulin 1 (NRG1) |
| EP2764863B1 (en) * | 2011-10-03 | 2020-03-11 | National Center for Geriatrics and Gerontology | Tau aggregation inhibitor |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| EP2962687B1 (en) | 2013-04-02 | 2019-06-05 | The Doshisha | Tau aggregation inhibitor |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| US5281624A (en) * | 1991-09-27 | 1994-01-25 | Eli Lilly And Company | N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof |
| US5658590A (en) * | 1995-01-11 | 1997-08-19 | Eli Lilly And Company | Treatment of attention-deficit/hyperactivity disorder |
| DE60022692T2 (de) * | 1999-07-01 | 2006-06-22 | Pharmacia & Upjohn Co. Llc, Kalamazoo | (S,S)-Reboxetin zur Behandlung von Migränekopfschmerzen |
| WO2001027068A1 (en) * | 1999-10-13 | 2001-04-19 | Pfizer Products Inc. | Biaryl ether derivatives useful as monoamine reuptake inhibitors |
| CA2431041A1 (en) * | 2001-01-02 | 2002-07-11 | Pharmacia & Upjohn Company | New drug combinations of norepinehrine reuptake inhibitors and neuroleptic agents |
| WO2002053104A2 (en) * | 2001-01-02 | 2002-07-11 | Sention, Inc. | Use of catecholamine reuptake inhibitors to enhance memory |
-
2002
- 2002-11-27 DE DE60223718T patent/DE60223718T2/de not_active Expired - Fee Related
- 2002-11-27 CA CA002467802A patent/CA2467802A1/en not_active Abandoned
- 2002-11-27 HR HR20040528A patent/HRPK20040528B3/xx not_active IP Right Cessation
- 2002-11-27 CZ CZ2004709A patent/CZ2004709A3/cs unknown
- 2002-11-27 KR KR10-2004-7009039A patent/KR20040066895A/ko not_active Withdrawn
- 2002-11-27 MX MXPA04005716A patent/MXPA04005716A/es not_active Application Discontinuation
- 2002-11-27 EP EP02789574A patent/EP1458368B1/en not_active Expired - Lifetime
- 2002-11-27 AU AU2002352625A patent/AU2002352625A1/en not_active Abandoned
- 2002-11-27 BR BR0213581-7A patent/BR0213581A/pt not_active IP Right Cessation
- 2002-11-27 US US10/496,765 patent/US20050009925A1/en not_active Abandoned
- 2002-11-27 ES ES02789574T patent/ES2295435T3/es not_active Expired - Lifetime
- 2002-11-27 SK SK244-2004A patent/SK2442004A3/sk not_active Application Discontinuation
- 2002-11-27 WO PCT/US2002/036132 patent/WO2003049724A1/en not_active Ceased
- 2002-11-27 IL IL16198902A patent/IL161989A0/xx unknown
- 2002-11-27 HU HU0402619A patent/HUP0402619A3/hu unknown
- 2002-11-27 PL PL02369311A patent/PL369311A1/xx unknown
- 2002-11-27 CN CNA028247264A patent/CN1713900A/zh active Pending
- 2002-11-27 NZ NZ532065A patent/NZ532065A/en unknown
- 2002-11-27 JP JP2003550773A patent/JP2005517647A/ja active Pending
- 2002-11-27 EA EA200400793A patent/EA200400793A1/ru unknown
- 2002-12-05 MY MYPI20024591A patent/MY136367A/en unknown
- 2002-12-05 TW TW091135296A patent/TW200300672A/zh unknown
-
2004
- 2004-05-31 ZA ZA200404274A patent/ZA200404274B/en unknown
- 2004-06-09 CO CO04054292A patent/CO5590907A2/es not_active Application Discontinuation
- 2004-06-09 EC EC2004005145A patent/ECSP045145A/es unknown
- 2004-07-09 NO NO20042904A patent/NO20042904L/no not_active Application Discontinuation
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