JP2005516997A5 - - Google Patents

Info

Publication number

JP2005516997A5

JP2005516997A5 JP2003565505A JP2003565505A JP2005516997A5 JP 2005516997 A5 JP2005516997 A5 JP 2005516997A5 JP 2003565505 A JP2003565505 A JP 2003565505A JP 2003565505 A JP2003565505 A JP 2003565505A JP 2005516997 A5 JP2005516997 A5 JP 2005516997A5

Authority

JP

Japan

Prior art keywords

mgf

use according

polypeptide

sequence

seq

Prior art date

2003-02-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 229920001184 polypeptide Polymers 0.000 claims 11
• 108090000765 processed proteins & peptides Proteins 0.000 claims 11
• 102000004196 processed proteins & peptides Human genes 0.000 claims 11
• 150000001413 amino acids Chemical class 0.000 claims 6
• 108091033319 polynucleotide Proteins 0.000 claims 6
• 102000040430 polynucleotide Human genes 0.000 claims 6
• 239000002157 polynucleotide Substances 0.000 claims 6
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 108700024394 Exon Proteins 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 3
• 208000028867 ischemia Diseases 0.000 claims 3
• 241000283973 Oryctolagus cuniculus Species 0.000 claims 2
• 230000037430 deletion Effects 0.000 claims 2
• 238000012217 deletion Methods 0.000 claims 2
• 239000012634 fragment Substances 0.000 claims 2
• 238000003780 insertion Methods 0.000 claims 2
• 230000037431 insertion Effects 0.000 claims 2
• 230000003680 myocardial damage Effects 0.000 claims 2
• 208000031225 myocardial ischemia Diseases 0.000 claims 2
• 238000006467 substitution reaction Methods 0.000 claims 2
• 230000001052 transient effect Effects 0.000 claims 2
• 239000013598 vector Substances 0.000 claims 2
• 108020004414 DNA Proteins 0.000 claims 1
• 241000282414 Homo sapiens Species 0.000 claims 1
• 101000716729 Homo sapiens Kit ligand Proteins 0.000 claims 1
• 101000832103 Homo sapiens Signal transducer and activator of transcription 5A Proteins 0.000 claims 1
• 241000700159 Rattus Species 0.000 claims 1
• 230000006907 apoptotic process Effects 0.000 claims 1
• 210000004413 cardiac myocyte Anatomy 0.000 claims 1
• 239000003102 growth factor Substances 0.000 claims 1
• 102000052934 human STAT5A Human genes 0.000 claims 1
• 230000001969 hypertrophic effect Effects 0.000 claims 1
• 238000007918 intramuscular administration Methods 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 208000010125 myocardial infarction Diseases 0.000 claims 1
• 210000004165 myocardium Anatomy 0.000 claims 1
• 239000013600 plasmid vector Substances 0.000 claims 1
• 230000002265 prevention Effects 0.000 claims 1
• 108010065307 rat mechano-growth factor Proteins 0.000 claims 1
• 239000013603 viral vector Substances 0.000 claims 1