JP2005516997A - 心筋損傷の阻止のためのインスリン様増殖因子ｉスプライス変異体の使用 - Google Patents
心筋損傷の阻止のためのインスリン様増殖因子ｉスプライス変異体の使用 Download PDFInfo
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- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| GBGB0202906.4A GB0202906D0 (en) | 2002-02-07 | 2002-02-07 | Prevention of myocardial damage |
| PCT/GB2003/000537 WO2003066082A1 (en) | 2002-02-07 | 2003-02-06 | Use of the insulin-like-growth factor i splice variant mgf for the prevention of myocardial damage |
Publications (2)
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| JP2005516997A true JP2005516997A (ja) | 2005-06-09 |
| JP2005516997A5 JP2005516997A5 (https=) | 2006-10-19 |
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| US (4) | US20050048028A1 (https=) |
| EP (1) | EP1480669B1 (https=) |
| JP (1) | JP2005516997A (https=) |
| AU (1) | AU2003244511A1 (https=) |
| DK (1) | DK1480669T3 (https=) |
| ES (1) | ES2432082T3 (https=) |
| GB (1) | GB0202906D0 (https=) |
| PT (1) | PT1480669E (https=) |
| WO (1) | WO2003066082A1 (https=) |
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| GB0202906D0 (en) | 2002-02-07 | 2002-03-27 | Univ London | Prevention of myocardial damage |
| AU2006224334A1 (en) * | 2005-03-18 | 2006-09-21 | The Board Of Trustees Of The University Of Illinois | Mecano growth factor peptides and their use |
| WO2006097682A1 (en) * | 2005-03-18 | 2006-09-21 | Ucl Business Plc | Mechano growth factor peptides and their use |
| KR101459789B1 (ko) | 2006-06-09 | 2014-11-07 | 노파르티스 아게 | 안정화된 인슐린-유사 성장 인자 폴리펩티드 |
| WO2009012443A1 (en) * | 2007-07-18 | 2009-01-22 | The Board Of Trustees Of The University Of Illinois | Nanoparticles for the elution of growth factors for recovery and regeneration of organs |
| CN101891812B (zh) * | 2010-07-09 | 2012-10-17 | 山西大学 | 力生长因子多肽及其制备方法和用途 |
| CN103031277B (zh) * | 2011-09-29 | 2015-07-15 | 重庆大学 | 力生长因子在制备无血清培养耐受型哺乳动物工程细胞中的应用 |
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| DE2460147C2 (de) | 1974-12-19 | 1983-05-05 | Ibm Deutschland Gmbh, 7000 Stuttgart | Anordnung zur Dekomprimierung komprimierter Information für aus schwarzen und weißen Bereichen zusammengesetze darzustellende Zeichen |
| US4732863A (en) | 1984-12-31 | 1988-03-22 | University Of New Mexico | PEG-modified antibody with reduced affinity for cell surface Fc receptors |
| US4963665A (en) | 1986-01-07 | 1990-10-16 | Washington University | Human preproinsulin-like growth factor I |
| US5080891A (en) * | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| SE8703625D0 (sv) | 1987-09-18 | 1987-09-18 | Kabivitrum Ab | New medical use |
| US5122614A (en) * | 1989-04-19 | 1992-06-16 | Enzon, Inc. | Active carbonates of polyalkylene oxides for modification of polypeptides |
| US5652214A (en) * | 1989-06-05 | 1997-07-29 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factors and analogs |
| US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
| DK0437563T3 (da) | 1989-08-07 | 1995-05-29 | Debio Rech Pharma Sa | Bioligiske aktive lægemiddelpolymerderivater |
| US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
| SE9100099D0 (sv) | 1991-01-11 | 1991-01-11 | Kabi Pharmacia Ab | Use of growth factor |
| SE9101341D0 (sv) | 1991-05-03 | 1991-05-03 | Kabi Pharmacia Ab | New medicinal use |
| US5861373A (en) * | 1991-08-01 | 1999-01-19 | Genentech, Inc | IGF-1 to improve the neural condition |
| EP0597033B1 (en) | 1991-08-01 | 1997-04-09 | Genentech, Inc. | Igf-1 to improve the neural condition |
| US5298422A (en) | 1991-11-06 | 1994-03-29 | Baylor College Of Medicine | Myogenic vector systems |
| EP0615452A4 (en) | 1991-11-25 | 1995-07-12 | Inst Molecular Biology Inc | MEDICINE SERVING THE PROMOTION OF THE GROWTH OF A NERVE IN MAMMALS. |
| FR2687681B1 (fr) * | 1992-02-20 | 1995-10-13 | Transgene Sa | Conjugues polyethyleneglycol-hirudine, leur procede de preparation et leur emploi pour le traitement des thromboses. |
| US5840900A (en) * | 1993-10-20 | 1998-11-24 | Enzon, Inc. | High molecular weight polymer-based prodrugs |
| AU1178395A (en) | 1993-11-12 | 1995-05-29 | North Shore University Hospital Research Corporation | Method of treating muscular dystrophy |
| US5730990A (en) * | 1994-06-24 | 1998-03-24 | Enzon, Inc. | Non-antigenic amine derived polymers and polymer conjugates |
| US5650496A (en) * | 1995-04-14 | 1997-07-22 | Cephalon, Inc. | IGF-I purification process |
| GB9605124D0 (en) * | 1996-03-11 | 1996-05-08 | Royal Free Hosp School Med | Method of treating muscular disorders |
| US6214966B1 (en) * | 1996-09-26 | 2001-04-10 | Shearwater Corporation | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution |
| DE69939036D1 (de) | 1998-04-28 | 2008-08-14 | Serono Lab | PEG Konjugate von LHRH Analogen |
| GB9926968D0 (en) | 1999-11-15 | 2000-01-12 | Univ London | Treatment of neurological disorders |
| GB0011278D0 (en) * | 2000-05-10 | 2000-06-28 | Univ London | Repair of nerve damage |
| GB0202906D0 (en) | 2002-02-07 | 2002-03-27 | Univ London | Prevention of myocardial damage |
| GB0203552D0 (en) | 2002-02-14 | 2002-04-03 | Beaumont Nicholas J | Peptide growth factor |
| WO2006097682A1 (en) | 2005-03-18 | 2006-09-21 | Ucl Business Plc | Mechano growth factor peptides and their use |
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2003
- 2003-02-06 JP JP2003565505A patent/JP2005516997A/ja active Pending
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2018
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| WO2003066082A1 (en) | 2003-08-14 |
| US20080039390A1 (en) | 2008-02-14 |
| US20130210723A1 (en) | 2013-08-15 |
| US20050048028A1 (en) | 2005-03-03 |
| ES2432082T3 (es) | 2013-11-29 |
| GB0202906D0 (en) | 2002-03-27 |
| PT1480669E (pt) | 2013-05-22 |
| US9919031B2 (en) | 2018-03-20 |
| US20180271942A1 (en) | 2018-09-27 |
| EP1480669A1 (en) | 2004-12-01 |
| EP1480669B1 (en) | 2013-01-23 |
| AU2003244511A1 (en) | 2003-09-02 |
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