JP2011509093A5 - - Google Patents
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- Publication number
- JP2011509093A5 JP2011509093A5 JP2010542283A JP2010542283A JP2011509093A5 JP 2011509093 A5 JP2011509093 A5 JP 2011509093A5 JP 2010542283 A JP2010542283 A JP 2010542283A JP 2010542283 A JP2010542283 A JP 2010542283A JP 2011509093 A5 JP2011509093 A5 JP 2011509093A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid residue
- peptide
- acid residues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2013708P | 2008-01-09 | 2008-01-09 | |
| US8064008P | 2008-07-14 | 2008-07-14 | |
| PCT/US2009/000155 WO2009089059A2 (en) | 2008-01-09 | 2009-01-09 | Therapeutic inhibitors of pai-1 function methods of their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012008069A Division JP2012135307A (ja) | 2008-01-09 | 2012-01-18 | Ｐａｉ−１機能の治療的阻害因子およびその使用法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011509093A JP2011509093A (ja) | 2011-03-24 |
| JP2011509093A5 true JP2011509093A5 (https=) | 2012-03-01 |
Family
ID=40853701
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010542283A Withdrawn JP2011509093A (ja) | 2008-01-09 | 2009-01-09 | Ｐａｉ−１機能の治療的阻害因子およびその使用法 |
| JP2012008069A Withdrawn JP2012135307A (ja) | 2008-01-09 | 2012-01-18 | Ｐａｉ−１機能の治療的阻害因子およびその使用法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012008069A Withdrawn JP2012135307A (ja) | 2008-01-09 | 2012-01-18 | Ｐａｉ−１機能の治療的阻害因子およびその使用法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8431363B2 (https=) |
| EP (1) | EP2242501A4 (https=) |
| JP (2) | JP2011509093A (https=) |
| KR (1) | KR101712208B1 (https=) |
| CN (1) | CN102123721A (https=) |
| AU (1) | AU2009204464B2 (https=) |
| BR (1) | BRPI0906867A2 (https=) |
| CA (1) | CA2711878A1 (https=) |
| IL (1) | IL206891A0 (https=) |
| MX (1) | MX2010007586A (https=) |
| RU (1) | RU2010133847A (https=) |
| WO (1) | WO2009089059A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0906867A2 (pt) | 2008-01-09 | 2019-09-24 | Intrexon Corp | inibidores terapêuticos da função pai-1 e métodos de uso dos mesmo |
| CN103154236B (zh) * | 2010-05-12 | 2016-08-31 | 再生医学Tx有限责任公司 | 生物活性肾细胞 |
| CN104271593B (zh) * | 2012-05-01 | 2018-01-16 | 富士胶片株式会社 | 多能干细胞的培养方法及该方法中使用的多肽 |
| CN103421781B (zh) * | 2012-07-04 | 2014-12-31 | 华中农业大学 | 猪肌肉组织特异性表达基因myf6启动子及应用 |
| KR20160089390A (ko) * | 2013-12-10 | 2016-07-27 | 에프. 호프만-라 로슈 아게 | 다중-하부단위 구조에 대한 약학적 활성 개체의 표적화 전달을 위한 다중-하부단위 구조의 하부단위의 결합 도메인의 용도 |
| WO2018107686A1 (zh) | 2016-12-15 | 2018-06-21 | 深圳瑞健生命科学研究院有限公司 | 一种治疗动脉粥样硬化及其并发症的方法 |
| JP7168990B2 (ja) | 2016-12-15 | 2022-11-10 | タレンゲン インターナショナル リミテッド | 肥満症を予防および治療するための方法および薬物 |
| TWI677348B (zh) | 2016-12-15 | 2019-11-21 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種改善心臟病變的方法 |
| US11613744B2 (en) | 2018-12-28 | 2023-03-28 | Vertex Pharmaceuticals Incorporated | Modified urokinase-type plasminogen activator polypeptides and methods of use |
| CA3123872A1 (en) | 2018-12-28 | 2020-07-02 | Catalyst Biosciences, Inc. | Modified urokinase-type plasminogen activator polypeptides and methods of use |
| CN119656313B (zh) * | 2024-12-13 | 2026-02-17 | 四川大学华西医院 | Serpine1基因作为靶点在制备预防或治疗心肌纤维化药物中的用途 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639726A (en) * | 1994-09-30 | 1997-06-17 | The Regents Of The University Of Michigan | Peptide mediated enhancement of thrombolysis methods and compositions |
| AU1191001A (en) * | 1999-10-07 | 2001-05-10 | Human Genome Sciences, Inc. | Plasminogen-like polynucleotides, polypeptides, and antibodies |
| DE10053251A1 (de) * | 2000-10-26 | 2002-05-08 | Boehringer Ingelheim Pharma | Epitope von PAI-1 |
| US20030211095A1 (en) * | 2002-05-08 | 2003-11-13 | Abd. Al-Roof Higazi | Peptide for regulation of urokinase plasminogen activator and method of optimizing therapeutic efficacy |
| US20030199463A1 (en) * | 2002-04-23 | 2003-10-23 | Silviu Itescu | DNA enzyme to inhibit plasminogen activator inhibitor-1 |
| JP2006507297A (ja) * | 2002-05-13 | 2006-03-02 | チルドレンズ・ホスピタル・ロサンジェルス | ケロイドおよび他の皮膚または内部創傷または病変における異常瘢痕形成の処置および予防 |
| US7241613B1 (en) * | 2002-06-05 | 2007-07-10 | Oscient Pharmaceuticals Corporation | Identification of Candida cell surface proteins and their uses |
| US7785871B2 (en) | 2002-10-09 | 2010-08-31 | Intrexon Corporation | DNA cloning vector plasmids and methods for their use |
| US20080050808A1 (en) * | 2002-10-09 | 2008-02-28 | Reed Thomas D | DNA modular cloning vector plasmids and methods for their use |
| US7071295B2 (en) * | 2002-12-02 | 2006-07-04 | Intrexon Corporation | Signal for targeting molecules to the sarco(endo)plasmic reticulum |
| CA2509222A1 (en) | 2002-12-10 | 2004-06-24 | Wyeth | Substituted indole oxo-acetyl amino acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1) |
| JP2007537755A (ja) | 2004-05-18 | 2007-12-27 | イントレクソン コーポレイション | Ｄｎａクローニングベクタープラスミドのダイナミックなベクター構築のための方法 |
| US8153598B2 (en) | 2005-10-19 | 2012-04-10 | Intrexon Corporation | PKD ligands and polynucleotides encoding PKD ligands |
| WO2007048103A2 (en) | 2006-10-18 | 2007-04-26 | Intrexon Corporation | Pkd ligands and polynucleotides encoding pkd ligands |
| US7943732B2 (en) * | 2006-06-05 | 2011-05-17 | Intrexon Corporation | AKT ligands and polynucleotides encoding AKT ligands |
| US8993263B2 (en) * | 2006-08-07 | 2015-03-31 | Intrexon Corporation | PKA ligands and polynucleotides encoding PKA ligands |
| US8999666B2 (en) * | 2006-08-09 | 2015-04-07 | Intrexon Corporation | PKC ligands and polynucleotides encoding PKC ligands |
| US8283445B2 (en) * | 2006-11-13 | 2012-10-09 | Intrexon Corporation | Extracellular-signal-regulated-kinase (ERK) heteropolyligand polypeptide |
| US8729225B2 (en) * | 2006-11-13 | 2014-05-20 | Intrexon Corporation | Glycogen synthase kinase heteropolyligand polypeptide |
| US7705122B2 (en) * | 2006-12-04 | 2010-04-27 | Intrexon Corporation | mTOR ligands and polynucleotides encoding mTOR ligands |
| EP2537924B1 (en) | 2007-03-27 | 2015-03-18 | Intrexon Corporation | MEK ligands and polynucleotides encoding mek ligands |
| CA2722754A1 (en) * | 2007-04-27 | 2009-01-29 | The University Of Toledo | Modified plasminogen activator inhibitor type-1 molecule and methods based thereon |
| BRPI0906867A2 (pt) | 2008-01-09 | 2019-09-24 | Intrexon Corp | inibidores terapêuticos da função pai-1 e métodos de uso dos mesmo |
-
2009
- 2009-01-09 BR BRPI0906867A patent/BRPI0906867A2/pt not_active IP Right Cessation
- 2009-01-09 RU RU2010133847/10A patent/RU2010133847A/ru not_active Application Discontinuation
- 2009-01-09 CN CN2009801088638A patent/CN102123721A/zh active Pending
- 2009-01-09 US US12/812,127 patent/US8431363B2/en not_active Expired - Fee Related
- 2009-01-09 WO PCT/US2009/000155 patent/WO2009089059A2/en not_active Ceased
- 2009-01-09 MX MX2010007586A patent/MX2010007586A/es active IP Right Grant
- 2009-01-09 CA CA2711878A patent/CA2711878A1/en not_active Abandoned
- 2009-01-09 EP EP09700772A patent/EP2242501A4/en not_active Withdrawn
- 2009-01-09 KR KR1020107017701A patent/KR101712208B1/ko not_active Expired - Fee Related
- 2009-01-09 AU AU2009204464A patent/AU2009204464B2/en not_active Ceased
- 2009-01-09 JP JP2010542283A patent/JP2011509093A/ja not_active Withdrawn
-
2010
- 2010-07-08 IL IL206891A patent/IL206891A0/en unknown
-
2012
- 2012-01-18 JP JP2012008069A patent/JP2012135307A/ja not_active Withdrawn
-
2013
- 2013-02-15 US US13/769,144 patent/US8828686B2/en not_active Expired - Fee Related
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