JP2005510609A - 多孔性支持体の後修飾 - Google Patents

多孔性支持体の後修飾 Download PDF

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Publication number
JP2005510609A
JP2005510609A JP2003547506A JP2003547506A JP2005510609A JP 2005510609 A JP2005510609 A JP 2005510609A JP 2003547506 A JP2003547506 A JP 2003547506A JP 2003547506 A JP2003547506 A JP 2003547506A JP 2005510609 A JP2005510609 A JP 2005510609A
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JP
Japan
Prior art keywords
post
support
polymeric support
macroporous
grafting
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Ceased
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JP2003547506A
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English (en)
Japanese (ja)
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JP2005510609A5 (https=
Inventor
ヘンリク・イーレ
アンデッシュ・ラーション
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Cytiva Sweden AB
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Amersham Bioscience AB
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Publication of JP2005510609A publication Critical patent/JP2005510609A/ja
Publication of JP2005510609A5 publication Critical patent/JP2005510609A5/ja
Ceased legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F251/00—Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F257/00—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
    • C08F257/02—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/36—After-treatment
    • C08J9/40—Impregnation
    • C08J9/405—Impregnation with polymerisable compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Graft Or Block Polymers (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP2003547506A 2001-11-26 2002-11-25 多孔性支持体の後修飾 Ceased JP2005510609A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0103968 2001-11-26
PCT/SE2002/002159 WO2003046063A1 (en) 2001-11-26 2002-11-25 Post-modification of a porous support

Publications (2)

Publication Number Publication Date
JP2005510609A true JP2005510609A (ja) 2005-04-21
JP2005510609A5 JP2005510609A5 (https=) 2008-10-09

Family

ID=20286116

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003547506A Ceased JP2005510609A (ja) 2001-11-26 2002-11-25 多孔性支持体の後修飾

Country Status (6)

Country Link
US (1) US7060187B2 (https=)
EP (1) EP1448684A1 (https=)
JP (1) JP2005510609A (https=)
AU (1) AU2002353728B2 (https=)
CA (1) CA2464086C (https=)
WO (1) WO2003046063A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012032390A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 向上したクロマトグラフィー媒体の製造方法および使用方法
JP2012032391A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 改良されたクロマトグラフィー媒体の製造方法および使用方法
JP2012032392A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co クロマトグラフィー媒体性能を向上させるグラフト化方法
JP2013532829A (ja) * 2010-07-29 2013-08-19 イー・エム・デイー・ミリポア・コーポレイシヨン クロマトグラフィーの媒介性能を改善するためのグラフト法
WO2014069474A1 (ja) * 2012-10-30 2014-05-08 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
JP2015086294A (ja) * 2013-10-30 2015-05-07 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
JP2017122653A (ja) * 2016-01-07 2017-07-13 日立化成株式会社 分離材及びカラム

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005510609A (ja) * 2001-11-26 2005-04-21 アメルシャム・バイオサイエンシーズ・アクチボラグ 多孔性支持体の後修飾
CA2464302A1 (en) * 2001-11-26 2003-06-05 Amersham Biosciences Ab Post-modification of a porous support
SE0201623D0 (sv) 2002-05-30 2002-05-30 Amersham Biosciences Ab Macroporous cross-linked polymer particles
SE0302509D0 (sv) * 2003-09-19 2003-09-19 Amersham Biosciences Ab Matrix for separation of polyethers and method of separation
SE0303532D0 (sv) * 2003-12-23 2003-12-23 Amersham Biosciences Ab Purification of immunoglobulins
SE0401665D0 (sv) 2004-06-24 2004-06-24 Amersham Biosciences Ab Purification of immunoglobulins
US20070055013A1 (en) * 2005-02-21 2007-03-08 Noriho Kamiya Substrate and method of immobilizing protein
FR2884253B1 (fr) * 2005-04-08 2007-06-22 Univ Lille Sciences Tech Materiaux monolithiques fonctionnalisables
US8137559B2 (en) * 2007-02-09 2012-03-20 Ge Healthcare Bio-Sciences Ab Liquid clarification
US9044740B2 (en) 2007-03-30 2015-06-02 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
JP2011016036A (ja) * 2007-11-26 2011-01-27 Asahi Kasei Chemicals Corp タンパク吸着材料およびその製造方法
JP5631869B2 (ja) * 2008-05-30 2014-11-26 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 水酸基を含まないポリマー上におけるＣｅ（ＩＶ）で開始されるグラフト重合
US8592493B2 (en) * 2008-06-26 2013-11-26 3M Innovative Properties Company Solid support with a grafted chain
EP2426492B1 (en) * 2009-04-30 2017-10-04 Daicel Corporation Separating agent for optical isomer
CN105658325A (zh) * 2013-10-10 2016-06-08 通用电气医疗集团生物工艺研发股份公司 生产色谱材料的方法
US10898877B2 (en) * 2015-01-19 2021-01-26 Showa Denko Materials Co., Ltd. Separation material
JP6939021B2 (ja) * 2017-03-30 2021-09-22 昭和電工マテリアルズ株式会社 分離材及びカラム
CN107446086B (zh) * 2017-09-06 2020-05-08 福建出入境检验检疫局检验检疫技术中心 一种六价铬印迹材料的制备方法

Citations (10)

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Publication number Priority date Publication date Assignee Title
JPS5272784A (en) * 1975-12-12 1977-06-17 Pharmacia Fine Chemicals Ab Dextrane derivative gel for electrophoresis separation
JPS55123610A (en) * 1979-03-17 1980-09-24 Nichiden Kagaku Kk Modified starch and its preparation
JPS57155212A (en) * 1981-03-20 1982-09-25 Kanegafuchi Chem Ind Co Ltd Modified polyvinyl chloride resin composition
JPS6263856A (ja) * 1985-09-13 1987-03-20 Japan Synthetic Rubber Co Ltd クロマトグラフイ−用充填剤の製造方法
JPH05170845A (ja) * 1991-12-20 1993-07-09 Nippon Paint Co Ltd 有機ポリマー微粒子およびその製法
JPH07171389A (ja) * 1993-12-21 1995-07-11 Mitsubishi Chem Corp 分離剤の製造方法
JPH07278204A (ja) * 1994-02-15 1995-10-24 Ciba Geigy Ag 不飽和炭水化物誘導体、そのポリマー及びその用途
WO1998040144A1 (en) * 1997-03-13 1998-09-17 Dionex Corporation Bifunctional crown ether-based cation-exchange stationary phase for liquid chromatography
US5929214A (en) * 1997-02-28 1999-07-27 Cornell Research Foundation, Inc. Thermally responsive polymer monoliths
JP2002022723A (ja) * 2000-07-05 2002-01-23 Mitsubishi Chemicals Corp 固体表面の修飾方法

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US4540742A (en) * 1982-11-12 1985-09-10 The B. F. Goodrich Company Graft copolymers and process for their preparation
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
US6022902A (en) * 1989-10-31 2000-02-08 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Porous article with surface functionality and method for preparing same
ATE161866T1 (de) * 1992-10-21 1998-01-15 Cornell Res Foundation Inc Selektive, die porengrösse betreffende chemische modifikation poröser materialien
SE9303790D0 (sv) * 1993-11-17 1993-11-17 Pharmacia Lkb Biotech A method for separation and synthetic polymers that can be used as separation media in the method
US5503933A (en) * 1994-02-25 1996-04-02 Purdue Research Foundation Covalently bonded coatings
JP3499978B2 (ja) * 1995-08-17 2004-02-23 株式会社日清製粉グループ本社 逆相系分離膜
US6114466A (en) * 1998-02-06 2000-09-05 Renal Tech International Llc Material for purification of physiological liquids of organism
TW594416B (en) * 2001-05-08 2004-06-21 Shipley Co Llc Photoimageable composition
JP2005510609A (ja) * 2001-11-26 2005-04-21 アメルシャム・バイオサイエンシーズ・アクチボラグ 多孔性支持体の後修飾

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5272784A (en) * 1975-12-12 1977-06-17 Pharmacia Fine Chemicals Ab Dextrane derivative gel for electrophoresis separation
JPS55123610A (en) * 1979-03-17 1980-09-24 Nichiden Kagaku Kk Modified starch and its preparation
JPS57155212A (en) * 1981-03-20 1982-09-25 Kanegafuchi Chem Ind Co Ltd Modified polyvinyl chloride resin composition
JPS6263856A (ja) * 1985-09-13 1987-03-20 Japan Synthetic Rubber Co Ltd クロマトグラフイ−用充填剤の製造方法
JPH05170845A (ja) * 1991-12-20 1993-07-09 Nippon Paint Co Ltd 有機ポリマー微粒子およびその製法
JPH07171389A (ja) * 1993-12-21 1995-07-11 Mitsubishi Chem Corp 分離剤の製造方法
JPH07278204A (ja) * 1994-02-15 1995-10-24 Ciba Geigy Ag 不飽和炭水化物誘導体、そのポリマー及びその用途
US5929214A (en) * 1997-02-28 1999-07-27 Cornell Research Foundation, Inc. Thermally responsive polymer monoliths
WO1998040144A1 (en) * 1997-03-13 1998-09-17 Dionex Corporation Bifunctional crown ether-based cation-exchange stationary phase for liquid chromatography
JP2002511924A (ja) * 1997-03-13 2002-04-16 ダイオネックス コーポレイション 液体クロマトグラフィー用の二官能クラウンエーテルをベースとする陽イオン交換固定相
JP2002022723A (ja) * 2000-07-05 2002-01-23 Mitsubishi Chemicals Corp 固体表面の修飾方法

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012032390A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 向上したクロマトグラフィー媒体の製造方法および使用方法
JP2012032391A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 改良されたクロマトグラフィー媒体の製造方法および使用方法
JP2012032392A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co クロマトグラフィー媒体性能を向上させるグラフト化方法
JP2013532829A (ja) * 2010-07-29 2013-08-19 イー・エム・デイー・ミリポア・コーポレイシヨン クロマトグラフィーの媒介性能を改善するためのグラフト法
WO2014069474A1 (ja) * 2012-10-30 2014-05-08 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
US9943825B2 (en) 2012-10-30 2018-04-17 Kuraray Co., Ltd. Porous graft copolymer particles, method for producing same, and adsorbent material using same
JP2015086294A (ja) * 2013-10-30 2015-05-07 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
JP2017122653A (ja) * 2016-01-07 2017-07-13 日立化成株式会社 分離材及びカラム

Also Published As

Publication number Publication date
EP1448684A1 (en) 2004-08-25
US20050065282A1 (en) 2005-03-24
AU2002353728B2 (en) 2008-04-10
AU2002353728A1 (en) 2003-06-10
WO2003046063A1 (en) 2003-06-05
US7060187B2 (en) 2006-06-13
CA2464086C (en) 2011-01-18
CA2464086A1 (en) 2003-06-05

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