JP2005510246A5 - - Google Patents

Download PDF

Info

Publication number
JP2005510246A5
JP2005510246A5 JP2003547635A JP2003547635A JP2005510246A5 JP 2005510246 A5 JP2005510246 A5 JP 2005510246A5 JP 2003547635 A JP2003547635 A JP 2003547635A JP 2003547635 A JP2003547635 A JP 2003547635A JP 2005510246 A5 JP2005510246 A5 JP 2005510246A5
Authority
JP
Japan
Prior art keywords
seq
referred
heavy chain
antibody
functional fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003547635A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005510246A (ja
JP4519464B2 (ja
Filing date
Publication date
Priority claimed from US09/995,529 external-priority patent/US7365167B2/en
Priority claimed from US10/011,250 external-priority patent/US7390885B2/en
Application filed filed Critical
Publication of JP2005510246A publication Critical patent/JP2005510246A/ja
Publication of JP2005510246A5 publication Critical patent/JP2005510246A5/ja
Application granted granted Critical
Publication of JP4519464B2 publication Critical patent/JP4519464B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2003547635A 2001-11-26 2002-11-26 ヒト化コラーゲン抗体および関連方法 Expired - Fee Related JP4519464B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/995,529 US7365167B2 (en) 2001-11-26 2001-11-26 Humanized collagen antibodies and related methods
US10/011,250 US7390885B2 (en) 2001-11-26 2001-12-06 Humanized collagen antibodies and related methods
PCT/US2002/038147 WO2003046204A2 (en) 2001-11-26 2002-11-26 Humanized collagen antibodies and related methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009167279A Division JP2009240324A (ja) 2001-11-26 2009-07-15 ヒト化コラーゲン抗体および関連方法

Publications (3)

Publication Number Publication Date
JP2005510246A JP2005510246A (ja) 2005-04-21
JP2005510246A5 true JP2005510246A5 (enExample) 2006-01-12
JP4519464B2 JP4519464B2 (ja) 2010-08-04

Family

ID=26682164

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003547635A Expired - Fee Related JP4519464B2 (ja) 2001-11-26 2002-11-26 ヒト化コラーゲン抗体および関連方法
JP2009167279A Withdrawn JP2009240324A (ja) 2001-11-26 2009-07-15 ヒト化コラーゲン抗体および関連方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009167279A Withdrawn JP2009240324A (ja) 2001-11-26 2009-07-15 ヒト化コラーゲン抗体および関連方法

Country Status (11)

Country Link
US (4) US7390885B2 (enExample)
EP (1) EP1478764B1 (enExample)
JP (2) JP4519464B2 (enExample)
CN (1) CN1596313B (enExample)
AT (1) ATE509955T1 (enExample)
AU (1) AU2009200070A1 (enExample)
CA (1) CA2468016A1 (enExample)
IL (1) IL162117A0 (enExample)
MX (1) MXPA04004857A (enExample)
NZ (1) NZ533408A (enExample)
WO (1) WO2003046204A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7658924B2 (en) 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
US7365167B2 (en) 2001-11-26 2008-04-29 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7541440B2 (en) * 2002-09-30 2009-06-02 Immunomedics, Inc. Chimeric, human and humanized anti-granulocyte antibodies and methods of use
EP1716181B1 (en) 2004-02-19 2009-12-16 Genentech, Inc. Cdr-repaired antibodies
WO2007024921A2 (en) * 2005-08-24 2007-03-01 Cell Matrix Combination therapies for inhibiting integrin-extracellular matrix interactions
EP2054442A2 (en) * 2006-06-14 2009-05-06 Cell-Matrix, Inc. Denatured collagen peptides and uses thereof
MX2008015830A (es) * 2006-06-30 2009-01-09 Novo Nordisk As Anticuerpos anti-nkg2a y usos de los mismos.
US8906367B2 (en) * 2007-01-05 2014-12-09 University Of Zurich Method of providing disease-specific binding molecules and targets
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
CA2701793C (en) 2007-10-05 2017-04-25 Genentech, Inc. Use of anti-amyloid beta antibody in ocular diseases
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
WO2010055950A1 (ja) * 2008-11-17 2010-05-20 財団法人ヒューマンサイエンス振興財団 癌間質の構成因子に対して特異的結合能を有する物質と抗腫瘍性化合物との複合体による新規の癌ターゲティング治療
DK3173792T3 (da) * 2009-03-30 2019-08-05 Novartis Ag Crp neo-epitop fibrose-assay
CA2773356A1 (en) 2009-10-20 2011-04-28 Maine Medical Center Compositions and methods for treating inflammation and fibrosis
CN103068396B (zh) * 2010-03-02 2016-07-06 诺沃姆德治疗公司 抑制c5和备解素相互作用的抗-备解素抗体在制备抑制交替途径活化的药剂中的用途
CN103179981B (zh) 2010-07-30 2017-02-08 Ac免疫有限公司 安全和功能性的人源化抗β‑淀粉样蛋白抗体
KR20130135869A (ko) * 2010-11-10 2013-12-11 니폰 가야꾸 가부시끼가이샤 항 단쇄 제4형 콜라겐 폴리펩타이드 항체 및 이를 포함하는 종양의 진단, 예방 또는 치료용 약제
EP2757875B2 (en) * 2011-09-19 2023-03-22 Kymab Limited Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
WO2013158217A1 (en) 2012-04-20 2013-10-24 Thomas Jefferson University Engineered antibody for inhibition of fibrosis
AU2013326932B2 (en) 2012-10-04 2019-06-06 Novelmed Therapeutics, Inc. Alternative pathway specific antibodies for treating hemolytic diseases
EP2970494B1 (en) 2013-03-14 2017-12-13 The Board of Regents of The University of Texas System Her3 specific monoclonal antibodies for diagnostic and therapeutic use
RU2759334C2 (ru) 2016-09-21 2021-11-12 Нексткьюр, Инк. Антитела против siglec-15 и способы их применения
JP7474702B2 (ja) 2018-03-28 2024-04-25 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム エキソソームから単離されたｄｎａにおけるエピジェネティック変化の同定法
US20220144926A1 (en) * 2018-10-16 2022-05-12 Board Of Regents, The University Of Texas System Identification and targeting of pathogenic extracellular matrix for diagnosis and treatment of cancer and other diseases
EP3880712A4 (en) 2018-11-16 2022-11-16 Albert Einstein College of Medicine MONOCLONAL ANTIBODIES AGAINST IgV DOMAIN OF B7-H3 AND USES THEREOF
CA3127556A1 (en) * 2019-01-28 2020-08-06 Tuojie Biotech (Shanghai) Co., Ltd. Anti-cd79b antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
WO2021252974A2 (en) * 2020-06-11 2021-12-16 Proviva Therapeutics (Hong Kong) Limited Collagen-targeted fusion proteins and antibodies
WO2022147298A1 (en) * 2020-12-31 2022-07-07 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Vascular-endothelial cadherin activating antibodies and uses thereof
US20240358850A1 (en) * 2023-04-13 2024-10-31 MaineHealth Compositions and methods for an antibody drug conjugate directed to a non-cell surface therapeutic target

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US91482A (en) * 1869-06-15 Improvement in harvesters
US4342566A (en) * 1980-02-22 1982-08-03 Scripps Clinic & Research Foundation Solid phase anti-C3 assay for detection of immune complexes
JPS6019790A (ja) * 1983-07-14 1985-01-31 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
DE3587500T2 (de) * 1984-12-04 1993-12-16 Lilly Co Eli Tumorbehandlung bei Säugetieren.
US5092885A (en) * 1987-02-12 1992-03-03 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Peptides with laminin activity
US5320970A (en) * 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6020145A (en) * 1989-06-30 2000-02-01 Bristol-Myers Squibb Company Methods for determining the presence of carcinoma using the antigen binding region of monoclonal antibody BR96
US5112946A (en) * 1989-07-06 1992-05-12 Repligen Corporation Modified pf4 compositions and methods of use
US5192744A (en) * 1990-01-12 1993-03-09 Northwestern University Method of inhibiting angiogenesis of tumors
US5202352A (en) * 1990-08-08 1993-04-13 Takeda Chemical Industries, Ltd. Intravascular embolizing agent containing angiogenesis-inhibiting substance
US5264563A (en) 1990-08-24 1993-11-23 Ixsys Inc. Process for synthesizing oligonucleotides with random codons
US5871974A (en) 1990-09-28 1999-02-16 Ixsys Inc. Surface expression libraries of heteromeric receptors
JP3105629B2 (ja) 1991-04-23 2000-11-06 サングスタット メディカル コーポレイション 特異的結合ペアのメンバーの細胞活性調節接合体
ATE188708T1 (de) 1991-08-21 2000-01-15 Novartis Ag Antikörperderivate
DE4127790A1 (de) 1991-08-22 1993-02-25 Wank Anna Verwendung von oligopeptiden mit 2 bis 5 peptidbindungen fuer kosmetische zwecke und einige neue oligopeptid-metallkomplexe
US5565332A (en) * 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
JPH0675216A (ja) 1992-08-27 1994-03-18 Hitachi Ltd 液晶表示装置
US6132976A (en) * 1992-12-04 2000-10-17 Shriners Hospitals For Children Immunoassays for the measurement of collagen denaturation and cleavage in cartilage
WO1994014070A1 (en) 1992-12-04 1994-06-23 Shriners Hospitals For Crippled Children Immunoassay for the measurement of collagen cleavage in cartilage
US5541295A (en) * 1993-02-12 1996-07-30 The Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations Detection of type II collagen and its peptides
EP0711415B1 (de) 1993-07-28 1998-07-22 Boehringer Mannheim Gmbh Immunoassay zum nachweis von kollagen typ i oder kollagenfragmenten davon
US5510391A (en) 1993-10-22 1996-04-23 Mayapple Holdings, Llc Method of treating blood vessel disorders of the skin using vitamin K
US5465826A (en) * 1994-02-24 1995-11-14 Valiant Machine & Tool, Inc. Conveyor system
US5560910A (en) 1994-08-26 1996-10-01 Crandall; Wilson T. Topical anti-inflammatory composition and method
US5763272A (en) * 1994-12-23 1998-06-09 Boehringer Mannheim Gmbh Hybridoma for producing antibody for collagen I
US5783184A (en) 1994-12-23 1998-07-21 Smithkline Beecham Corporation Method for treatment and diagnosis of IL-5 mediated disorders
US5756775A (en) * 1995-12-13 1998-05-26 Eli Lilly And Company Process to make α,α-difluoro-β-hydroxyl thiol esters
US6001994A (en) * 1995-12-13 1999-12-14 Eli Lilly And Company Process for making gemcitabine hydrochloride
WO1997039746A1 (en) 1996-04-22 1997-10-30 Advanced Polymer Systems, Inc. Method of and composition for treating disorders of the skin using vitamin k
WO1997044059A2 (en) 1996-05-23 1997-11-27 Shriner's Hospitals For Children Cartilage type ii collagen as an angiogenic factor
US6492508B1 (en) 1996-06-03 2002-12-10 United States Surgical Corp. A Division Of Tyco Healthcare Group Nucleic acids encoding extracellular matrix proteins
WO1999011208A1 (en) 1997-08-28 1999-03-11 Williams C Donald Method and composition for transdermal administration of pharmacologic agents
US6590079B2 (en) * 1997-01-30 2003-07-08 Ixsys, Incorporated Anti-αvβ3 recombinant human antibodies, nucleic acids encoding same
GB9702252D0 (en) 1997-02-06 1997-03-26 Univ Sheffield Medical The Sch Collagen assay
US5817699A (en) * 1997-05-30 1998-10-06 Flores; John A. Process for the preparation of ketamine ointment
ATE258310T1 (de) * 1997-07-31 2004-02-15 Metra Biosystems Inc Testverfahren für collagenpeptid
EP1007967A2 (en) 1997-08-04 2000-06-14 Ixsys, Incorporated Methods for identifying ligand specific binding molecules
US6030792A (en) 1997-11-13 2000-02-29 Pfizer Inc Assays for measurement of protein fragments in biological media
ATE301715T1 (de) 1998-10-16 2005-08-15 Fraunhofer Ges Forschung Durch molekulares pathogenicid vermittelte krankheitsresistenz in pflanzen
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
CA2358517C (en) * 1999-01-06 2012-10-09 University Of Southern California Method and composition for angiogenesis inhibition
US6521593B1 (en) * 1999-02-01 2003-02-18 Childrens Hospital Los Angeles Methods for inhibiting brain tumor growth
US6531580B1 (en) 1999-06-24 2003-03-11 Ixsys, Inc. Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same
DE60042487D1 (de) 1999-07-13 2009-08-13 Univ Southern California Methode und zusammensetzung zur angiogenese-inhibierung mit antagonisten gegen mmp-9 und beta1-integrine
JP2003511696A (ja) 1999-10-13 2003-03-25 インサイト・ゲノミックス・インコーポレイテッド 多重的サイトカイン分析
US6849425B1 (en) 1999-10-14 2005-02-01 Ixsys, Inc. Methods of optimizing antibody variable region binding affinity
ES2293973T3 (es) 2000-02-03 2008-04-01 Millennium Pharm Inc Anticuerpos anti-ccr2 humanizados y metodos de uso de los mismos.
WO2001066144A2 (en) * 2000-03-08 2001-09-13 Rhode Island Hospital, A Lifespan Partner Antineoplastic combination comprising an inhibitor of angiogenesis and an inhibitor of dna topoisomerase i enzyme activity
US6696254B2 (en) 2001-11-21 2004-02-24 Kimberly-Clark Worldwide, Inc. Detection and identification of enteric bacteria
US7365167B2 (en) 2001-11-26 2008-04-29 Cell Matrix, Inc. Humanized collagen antibodies and related methods
WO2005017485A2 (en) 2003-05-22 2005-02-24 Agdia, Inc. Multiplex enzyme-linked immunosorbent assay for detecting multiple analytes
JP2005347062A (ja) 2004-06-02 2005-12-15 Hitachi Displays Ltd バックライト装置及び液晶表示装置
JP2006075216A (ja) 2004-09-07 2006-03-23 Toshiba Corp 医用画像処理システム、医用画像処理プログラムおよび医用画像処理方法
EP2054442A2 (en) 2006-06-14 2009-05-06 Cell-Matrix, Inc. Denatured collagen peptides and uses thereof

Similar Documents

Publication Publication Date Title
JP2005510246A5 (enExample)
JP2025111463A5 (enExample)
JP2024167313A5 (enExample)
JP2025160458A5 (enExample)
JP2022031635A5 (enExample)
RU2006115835A (ru) Человеческие антитела против человеческого 4-1вв (cd137)
JP2011509245A5 (enExample)
HRP20181069T1 (hr) Antagonistička protutijela na il-17
ME02581B (me) Farmaceutski pripravci s otpornošću na topljivi cea
JP2009225799A5 (enExample)
JP2005519580A5 (enExample)
JP2005503789A5 (enExample)
JP2004527212A5 (enExample)
JP2010502183A5 (enExample)
JP2020531438A5 (ja) Ｎｋｇ２ｄ、ｃｄ１６、およびｈｌａ−ｅに結合するタンパク質
JP2010533498A5 (enExample)
JP2010536384A5 (enExample)
JP2008532949A5 (enExample)
JP2010511388A5 (enExample)
WO2002072832A3 (en) Therapeutic binding molecules
JP2008538292A5 (enExample)
JP2012500020A5 (enExample)
JP2018537421A5 (enExample)
JP2010524435A5 (enExample)
JP2012532851A5 (enExample)