AU2009200070A1 - Humanized collagen antibodies and related methods - Google Patents

Humanized collagen antibodies and related methods Download PDF

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Publication number
AU2009200070A1
AU2009200070A1 AU2009200070A AU2009200070A AU2009200070A1 AU 2009200070 A1 AU2009200070 A1 AU 2009200070A1 AU 2009200070 A AU2009200070 A AU 2009200070A AU 2009200070 A AU2009200070 A AU 2009200070A AU 2009200070 A1 AU2009200070 A1 AU 2009200070A1
Authority
AU
Australia
Prior art keywords
seq
referenced
antibody
heavy chain
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009200070A
Other languages
English (en)
Inventor
Daniel Broek
Peter C. Brooks
William D. Huse
Ying Tang
Jeffry D. Watkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Matrix Inc
Original Assignee
Cell Matrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/995,529 external-priority patent/US7365167B2/en
Priority claimed from AU2002360439A external-priority patent/AU2002360439B2/en
Application filed by Cell Matrix Inc filed Critical Cell Matrix Inc
Priority to AU2009200070A priority Critical patent/AU2009200070A1/en
Publication of AU2009200070A1 publication Critical patent/AU2009200070A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6843—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2009200070A 2001-11-26 2009-01-08 Humanized collagen antibodies and related methods Abandoned AU2009200070A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2009200070A AU2009200070A1 (en) 2001-11-26 2009-01-08 Humanized collagen antibodies and related methods

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09/995,529 2001-11-26
US09/995,529 US7365167B2 (en) 2001-11-26 2001-11-26 Humanized collagen antibodies and related methods
US10/011,250 2001-12-06
US10/011,250 US7390885B2 (en) 2001-11-26 2001-12-06 Humanized collagen antibodies and related methods
PCT/US2002/038147 WO2003046204A2 (en) 2001-11-26 2002-11-26 Humanized collagen antibodies and related methods
AU2002360439A AU2002360439B2 (en) 2001-11-26 2002-11-26 Humanized collagen antibodies and related methods
AU2009200070A AU2009200070A1 (en) 2001-11-26 2009-01-08 Humanized collagen antibodies and related methods

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2002360439A Division AU2002360439B2 (en) 2001-11-26 2002-11-26 Humanized collagen antibodies and related methods

Publications (1)

Publication Number Publication Date
AU2009200070A1 true AU2009200070A1 (en) 2009-02-05

Family

ID=26682164

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009200070A Abandoned AU2009200070A1 (en) 2001-11-26 2009-01-08 Humanized collagen antibodies and related methods

Country Status (11)

Country Link
US (4) US7390885B2 (enExample)
EP (1) EP1478764B1 (enExample)
JP (2) JP4519464B2 (enExample)
CN (1) CN1596313B (enExample)
AT (1) ATE509955T1 (enExample)
AU (1) AU2009200070A1 (enExample)
CA (1) CA2468016A1 (enExample)
IL (1) IL162117A0 (enExample)
MX (1) MXPA04004857A (enExample)
NZ (1) NZ533408A (enExample)
WO (1) WO2003046204A2 (enExample)

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US7365167B2 (en) 2001-11-26 2008-04-29 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7541440B2 (en) * 2002-09-30 2009-06-02 Immunomedics, Inc. Chimeric, human and humanized anti-granulocyte antibodies and methods of use
EP2168986A3 (en) 2004-02-19 2010-07-28 Genentech, Inc. CDR-repaired antibodies
CA2619654A1 (en) * 2005-08-24 2007-03-01 Cell Matrix Combination therapies for inhibiting integrin-extracellular matrix interactions
EP2054442A2 (en) * 2006-06-14 2009-05-06 Cell-Matrix, Inc. Denatured collagen peptides and uses thereof
DK2038306T3 (en) * 2006-06-30 2015-03-09 Novo Nordisk As ANTI-NKG2A ANTIBODIES AND APPLICATIONS THEREOF
HUE033325T2 (en) * 2007-01-05 2017-11-28 Univ Zuerich Anti-beta-amyloid binder antibodies and their use
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US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
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US9926366B2 (en) 2012-10-04 2018-03-27 Novelmed Therapeutics, Inc. Methods of treating a hemolytic disorder comprising administering anti-properdin antibodies
EP2970494B1 (en) 2013-03-14 2017-12-13 The Board of Regents of The University of Texas System Her3 specific monoclonal antibodies for diagnostic and therapeutic use
KR102644544B1 (ko) * 2016-09-21 2024-03-11 넥스트큐어 인코포레이티드 Siglec-15를 위한 항체 및 이의 사용 방법
CA3095134A1 (en) 2018-03-28 2019-10-03 Board Of Regents, The University Of Texas System Identification of epigenetic alterations in dna isolated from exosomes
EP3866831A4 (en) * 2018-10-16 2022-08-24 Board of Regents, The University of Texas System IDENTIFICATION AND TARGETING OF PATHOGENIC EXTRACELLULAR MATRIX FOR DIAGNOSIS AND TREATMENT OF CANCER AND OTHER DISEASES
CN113330034A (zh) 2018-11-16 2021-08-31 阿尔伯特爱因斯坦医学院 针对B7-H3的IgV结构域的单克隆抗体及其用途
CA3127556A1 (en) * 2019-01-28 2020-08-06 Tuojie Biotech (Shanghai) Co., Ltd. Anti-cd79b antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
US20230257453A1 (en) * 2020-06-11 2023-08-17 Proviva Therapeutics (Hong Kong) Limited Collagen-targeted fusion proteins and antibodies
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Also Published As

Publication number Publication date
AU2002360439A2 (en) 2003-06-10
NZ533408A (en) 2006-06-30
ATE509955T1 (de) 2011-06-15
JP2009240324A (ja) 2009-10-22
CN1596313B (zh) 2010-05-26
WO2003046204A2 (en) 2003-06-05
US20080260733A1 (en) 2008-10-23
AU2002360439A1 (en) 2003-06-10
CN1596313A (zh) 2005-03-16
US7566770B2 (en) 2009-07-28
US20080050388A1 (en) 2008-02-28
WO2003046204A3 (en) 2004-09-23
US7390885B2 (en) 2008-06-24
IL162117A0 (en) 2005-11-20
JP4519464B2 (ja) 2010-08-04
CA2468016A1 (en) 2003-06-05
EP1478764A2 (en) 2004-11-24
EP1478764B1 (en) 2011-05-18
US20070077199A1 (en) 2007-04-05
US20100303726A1 (en) 2010-12-02
HK1076128A1 (zh) 2006-01-06
EP1478764A4 (en) 2007-05-23
JP2005510246A (ja) 2005-04-21
MXPA04004857A (es) 2005-04-11
US7763248B2 (en) 2010-07-27
WO2003046204A8 (en) 2004-07-08

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application