AU2009200070A1 - Humanized collagen antibodies and related methods - Google Patents
Humanized collagen antibodies and related methods Download PDFInfo
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- AU2009200070A1 AU2009200070A1 AU2009200070A AU2009200070A AU2009200070A1 AU 2009200070 A1 AU2009200070 A1 AU 2009200070A1 AU 2009200070 A AU2009200070 A AU 2009200070A AU 2009200070 A AU2009200070 A AU 2009200070A AU 2009200070 A1 AU2009200070 A1 AU 2009200070A1
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6843—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a material from animals or humans
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
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- Chemical & Material Sciences (AREA)
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- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
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- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US10/011,250 | 2001-12-06 | ||
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| AU2002360439A AU2002360439B2 (en) | 2001-11-26 | 2002-11-26 | Humanized collagen antibodies and related methods |
| PCT/US2002/038147 WO2003046204A2 (en) | 2001-11-26 | 2002-11-26 | Humanized collagen antibodies and related methods |
| AU2009200070A AU2009200070A1 (en) | 2001-11-26 | 2009-01-08 | Humanized collagen antibodies and related methods |
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| EP (1) | EP1478764B1 (enExample) |
| JP (2) | JP4519464B2 (enExample) |
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| AT (1) | ATE509955T1 (enExample) |
| AU (1) | AU2009200070A1 (enExample) |
| CA (1) | CA2468016A1 (enExample) |
| IL (1) | IL162117A0 (enExample) |
| MX (1) | MXPA04004857A (enExample) |
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| WO (1) | WO2003046204A2 (enExample) |
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| US7658924B2 (en) | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
| US7365167B2 (en) | 2001-11-26 | 2008-04-29 | Cell Matrix, Inc. | Humanized collagen antibodies and related methods |
| US7541440B2 (en) * | 2002-09-30 | 2009-06-02 | Immunomedics, Inc. | Chimeric, human and humanized anti-granulocyte antibodies and methods of use |
| EP1716181B1 (en) | 2004-02-19 | 2009-12-16 | Genentech, Inc. | Cdr-repaired antibodies |
| WO2007024921A2 (en) * | 2005-08-24 | 2007-03-01 | Cell Matrix | Combination therapies for inhibiting integrin-extracellular matrix interactions |
| EP2054442A2 (en) * | 2006-06-14 | 2009-05-06 | Cell-Matrix, Inc. | Denatured collagen peptides and uses thereof |
| MX2008015830A (es) * | 2006-06-30 | 2009-01-09 | Novo Nordisk As | Anticuerpos anti-nkg2a y usos de los mismos. |
| US8906367B2 (en) * | 2007-01-05 | 2014-12-09 | University Of Zurich | Method of providing disease-specific binding molecules and targets |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| CA2701793C (en) | 2007-10-05 | 2017-04-25 | Genentech, Inc. | Use of anti-amyloid beta antibody in ocular diseases |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| WO2010055950A1 (ja) * | 2008-11-17 | 2010-05-20 | 財団法人ヒューマンサイエンス振興財団 | 癌間質の構成因子に対して特異的結合能を有する物質と抗腫瘍性化合物との複合体による新規の癌ターゲティング治療 |
| DK3173792T3 (da) * | 2009-03-30 | 2019-08-05 | Novartis Ag | Crp neo-epitop fibrose-assay |
| CA2773356A1 (en) | 2009-10-20 | 2011-04-28 | Maine Medical Center | Compositions and methods for treating inflammation and fibrosis |
| CN103068396B (zh) * | 2010-03-02 | 2016-07-06 | 诺沃姆德治疗公司 | 抑制c5和备解素相互作用的抗-备解素抗体在制备抑制交替途径活化的药剂中的用途 |
| CN103179981B (zh) | 2010-07-30 | 2017-02-08 | Ac免疫有限公司 | 安全和功能性的人源化抗β‑淀粉样蛋白抗体 |
| KR20130135869A (ko) * | 2010-11-10 | 2013-12-11 | 니폰 가야꾸 가부시끼가이샤 | 항 단쇄 제4형 콜라겐 폴리펩타이드 항체 및 이를 포함하는 종양의 진단, 예방 또는 치료용 약제 |
| EP2757875B2 (en) * | 2011-09-19 | 2023-03-22 | Kymab Limited | Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics |
| WO2013158217A1 (en) | 2012-04-20 | 2013-10-24 | Thomas Jefferson University | Engineered antibody for inhibition of fibrosis |
| AU2013326932B2 (en) | 2012-10-04 | 2019-06-06 | Novelmed Therapeutics, Inc. | Alternative pathway specific antibodies for treating hemolytic diseases |
| EP2970494B1 (en) | 2013-03-14 | 2017-12-13 | The Board of Regents of The University of Texas System | Her3 specific monoclonal antibodies for diagnostic and therapeutic use |
| RU2759334C2 (ru) | 2016-09-21 | 2021-11-12 | Нексткьюр, Инк. | Антитела против siglec-15 и способы их применения |
| JP7474702B2 (ja) | 2018-03-28 | 2024-04-25 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | エキソソームから単離されたｄｎａにおけるエピジェネティック変化の同定法 |
| US20220144926A1 (en) * | 2018-10-16 | 2022-05-12 | Board Of Regents, The University Of Texas System | Identification and targeting of pathogenic extracellular matrix for diagnosis and treatment of cancer and other diseases |
| EP3880712A4 (en) | 2018-11-16 | 2022-11-16 | Albert Einstein College of Medicine | MONOCLONAL ANTIBODIES AGAINST IgV DOMAIN OF B7-H3 AND USES THEREOF |
| CA3127556A1 (en) * | 2019-01-28 | 2020-08-06 | Tuojie Biotech (Shanghai) Co., Ltd. | Anti-cd79b antibody, antigen-binding fragment thereof, and pharmaceutical use thereof |
| WO2021252974A2 (en) * | 2020-06-11 | 2021-12-16 | Proviva Therapeutics (Hong Kong) Limited | Collagen-targeted fusion proteins and antibodies |
| WO2022147298A1 (en) * | 2020-12-31 | 2022-07-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Vascular-endothelial cadherin activating antibodies and uses thereof |
| US20240358850A1 (en) * | 2023-04-13 | 2024-10-31 | MaineHealth | Compositions and methods for an antibody drug conjugate directed to a non-cell surface therapeutic target |
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-
2001
- 2001-12-06 US US10/011,250 patent/US7390885B2/en not_active Expired - Fee Related
-
2002
- 2002-11-26 AT AT02795695T patent/ATE509955T1/de not_active IP Right Cessation
- 2002-11-26 EP EP02795695A patent/EP1478764B1/en not_active Expired - Lifetime
- 2002-11-26 CA CA002468016A patent/CA2468016A1/en not_active Abandoned
- 2002-11-26 NZ NZ533408A patent/NZ533408A/en not_active IP Right Cessation
- 2002-11-26 IL IL16211702A patent/IL162117A0/xx unknown
- 2002-11-26 WO PCT/US2002/038147 patent/WO2003046204A2/en not_active Ceased
- 2002-11-26 JP JP2003547635A patent/JP4519464B2/ja not_active Expired - Fee Related
- 2002-11-26 CN CN028264126A patent/CN1596313B/zh not_active Expired - Fee Related
- 2002-11-26 MX MXPA04004857A patent/MXPA04004857A/es not_active Application Discontinuation
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2006
- 2006-07-14 US US11/486,894 patent/US7566770B2/en not_active Expired - Fee Related
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2008
- 2008-05-08 US US12/117,642 patent/US7763248B2/en not_active Expired - Fee Related
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2009
- 2009-01-08 AU AU2009200070A patent/AU2009200070A1/en not_active Abandoned
- 2009-07-15 JP JP2009167279A patent/JP2009240324A/ja not_active Withdrawn
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2003046204A8 (en) | 2004-07-08 |
| US7390885B2 (en) | 2008-06-24 |
| AU2002360439A2 (en) | 2003-06-10 |
| US7763248B2 (en) | 2010-07-27 |
| US20100303726A1 (en) | 2010-12-02 |
| NZ533408A (en) | 2006-06-30 |
| HK1076128A1 (zh) | 2006-01-06 |
| MXPA04004857A (es) | 2005-04-11 |
| US20080050388A1 (en) | 2008-02-28 |
| ATE509955T1 (de) | 2011-06-15 |
| IL162117A0 (en) | 2005-11-20 |
| WO2003046204A2 (en) | 2003-06-05 |
| CN1596313A (zh) | 2005-03-16 |
| JP2005510246A (ja) | 2005-04-21 |
| US20070077199A1 (en) | 2007-04-05 |
| EP1478764A4 (en) | 2007-05-23 |
| EP1478764B1 (en) | 2011-05-18 |
| US7566770B2 (en) | 2009-07-28 |
| EP1478764A2 (en) | 2004-11-24 |
| CN1596313B (zh) | 2010-05-26 |
| WO2003046204A3 (en) | 2004-09-23 |
| JP2009240324A (ja) | 2009-10-22 |
| AU2002360439A1 (en) | 2003-06-10 |
| US20080260733A1 (en) | 2008-10-23 |
| CA2468016A1 (en) | 2003-06-05 |
| JP4519464B2 (ja) | 2010-08-04 |
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