JP2005508953A5 - - Google Patents

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Publication number
JP2005508953A5
JP2005508953A5 JP2003534421A JP2003534421A JP2005508953A5 JP 2005508953 A5 JP2005508953 A5 JP 2005508953A5 JP 2003534421 A JP2003534421 A JP 2003534421A JP 2003534421 A JP2003534421 A JP 2003534421A JP 2005508953 A5 JP2005508953 A5 JP 2005508953A5
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JP
Japan
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hydrogen
compound
alkyl
compound according
ring
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JP2003534421A
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English (en)
Japanese (ja)
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JP2005508953A (ja
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Priority claimed from PCT/US2002/032354 external-priority patent/WO2003031438A1/en
Publication of JP2005508953A publication Critical patent/JP2005508953A/ja
Publication of JP2005508953A5 publication Critical patent/JP2005508953A5/ja
Withdrawn legal-status Critical Current

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JP2003534421A 2001-10-10 2002-10-10 キナーゼ阻害剤としての３−［４−（置換ヘテロサイクリル）−ピロール−２−イルメチリデン］−２−インドリノン誘導体 Withdrawn JP2005508953A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32822601P 2001-10-10 2001-10-10
PCT/US2002/032354 WO2003031438A1 (en) 2001-10-10 2002-10-10 3-[4-(substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone derivatives as kinase inhibitors

Publications (2)

Publication Number Publication Date
JP2005508953A JP2005508953A (ja) 2005-04-07
JP2005508953A5 true JP2005508953A5 (https=) 2006-01-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003534421A Withdrawn JP2005508953A (ja) 2001-10-10 2002-10-10 キナーゼ阻害剤としての３−［４−（置換ヘテロサイクリル）−ピロール−２−イルメチリデン］−２−インドリノン誘導体

Country Status (7)

Country Link
US (1) US6642232B2 (https=)
EP (1) EP1434774A1 (https=)
JP (1) JP2005508953A (https=)
BR (1) BR0213185A (https=)
CA (1) CA2462950A1 (https=)
MX (1) MXPA04003385A (https=)
WO (1) WO2003031438A1 (https=)

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US20100256392A1 (en) * 2007-11-21 2010-10-07 Teva Pharmaceutical Industries Ltd. Polymorphs of sunitinib base and processes for preparation thereof
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US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
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US8063058B2 (en) 2008-04-16 2011-11-22 Portola Pharmaceuticals, Inc. Inhibitors of syk and JAK protein kinases
CA2731605A1 (en) * 2008-07-24 2010-01-28 Teva Pharmaceutical Industries Ltd. Sunitinib and salts thereof and their polymorphs
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MX2013011481A (es) * 2011-04-08 2014-02-17 Beta Pharma Inc Nuevos inhibidores de cinasa de proteina de indolinona.
MX363551B (es) 2011-11-23 2019-03-27 Portola Pharmaceuticals Inc Star Compuestos derivados de pirazina como inhibidores de cinasa.
CN104829596B (zh) * 2014-02-10 2017-02-01 石家庄以岭药业股份有限公司 吡咯取代吲哚酮类衍生物、其制备方法、包含该衍生物的组合物、及其用途
WO2018059556A1 (zh) 2016-09-29 2018-04-05 贝达药业股份有限公司 激酶抑制剂化合物的多晶型、含其的药物组合物及其制备方法和应用

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