JP2005503327A5 - - Google Patents
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- Publication number
- JP2005503327A5 JP2005503327A5 JP2002564480A JP2002564480A JP2005503327A5 JP 2005503327 A5 JP2005503327 A5 JP 2005503327A5 JP 2002564480 A JP2002564480 A JP 2002564480A JP 2002564480 A JP2002564480 A JP 2002564480A JP 2005503327 A5 JP2005503327 A5 JP 2005503327A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxy
- isophthalamide
- benzyl
- ylmethyl
- benzodioxol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*c(c(C(OC)=O)c1)c(*)c(*)c1C(O*(C)(C)*)=O Chemical compound C*c(c(C(OC)=O)c1)c(*)c(*)c1C(O*(C)(C)*)=O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26873601P | 2001-02-14 | 2001-02-14 | |
| PCT/IB2002/000344 WO2002064547A2 (en) | 2001-02-14 | 2002-02-04 | Isophthalic acid derivatives as matrix metalloproteinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005503327A JP2005503327A (ja) | 2005-02-03 |
| JP2005503327A5 true JP2005503327A5 (enExample) | 2008-05-29 |
Family
ID=23024241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002564480A Pending JP2005503327A (ja) | 2001-02-14 | 2002-02-04 | マトリックスメタロプロテイナーゼ阻害剤としてのイソフタル酸誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6995151B2 (enExample) |
| EP (1) | EP1362028A2 (enExample) |
| JP (1) | JP2005503327A (enExample) |
| AR (1) | AR032679A1 (enExample) |
| BR (1) | BR0207201A (enExample) |
| CA (1) | CA2435376A1 (enExample) |
| DO (1) | DOP2002000333A (enExample) |
| MX (1) | MXPA03006598A (enExample) |
| PA (1) | PA8539801A1 (enExample) |
| PE (1) | PE20020859A1 (enExample) |
| TN (1) | TNSN02008A1 (enExample) |
| UY (1) | UY27169A1 (enExample) |
| WO (1) | WO2002064547A2 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DOP2002000333A (es) * | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz |
| DOP2002000332A (es) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| WO2002064571A1 (en) | 2001-02-14 | 2002-08-22 | Warner-Lambert Company Llc | Pyrimidine matrix metalloproteinase inhibitors |
| US6924276B2 (en) * | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
| EP1434585A1 (en) | 2001-10-12 | 2004-07-07 | Warner-Lambert Company LLC | Alkyne matrix metalloproteinase inhibitors |
| US6962922B2 (en) | 2001-10-12 | 2005-11-08 | Warner-Lambert Company Llc | Alkynylated quinazoline compounds |
| DE10160357A1 (de) * | 2001-12-08 | 2003-06-18 | Aventis Pharma Gmbh | Verwendung von Pyridin-2,4-dicarbonsäurediamiden und Pyrimidin-4,6-dicarbonsäurediamiden zur selektiven Inhibierung von Kollagenasen |
| US6894057B2 (en) | 2002-03-08 | 2005-05-17 | Warner-Lambert Company | Oxo-azabicyclic compounds |
| US6747147B2 (en) | 2002-03-08 | 2004-06-08 | Warner-Lambert Company | Oxo-azabicyclic compounds |
| US20040006077A1 (en) * | 2002-06-25 | 2004-01-08 | Bernard Gaudilliere | Thiazine and oxazine derivatives as MMP-13 inhibitors |
| CA2495432A1 (en) * | 2002-07-17 | 2004-01-22 | Warner-Lambert Company Llc | Combination of an allosteric carboxylic inhibitor of matrix metalloproteinase-13 with celecoxib or valdecoxib |
| CA2492391A1 (en) * | 2002-07-17 | 2004-01-22 | Warner-Lambert Company Llc | Combination of an allosteric inhibitor of matrix metalloproteinase-13 with a selective inhibitor of cyclooxygenase-2 that is not celecoxib or valdecoxib |
| EP1534274A1 (en) * | 2002-07-17 | 2005-06-01 | Warner-Lambert Company LLC | Combination of an allosteric alkyne inhibitor of matrix metalloproteinase-13 with celecoxib or valdecoxib |
| EP1536786A1 (en) * | 2002-07-17 | 2005-06-08 | Warner-Lambert Company Llc | Combination of an allosteric inhibitor of matrix metalloproteinase-13 with celecoxib or valdecoxib |
| PA8578101A1 (es) * | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
| EP1537098A1 (en) | 2002-08-13 | 2005-06-08 | Warner-Lambert Company LLC | Monocyclic derivatives as matrix metalloproteinase inhibitors |
| EP1394159A1 (fr) * | 2002-08-13 | 2004-03-03 | Warner-Lambert Company LLC | Nouveaux dérivés de thiophène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
| AU2003250466A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | 3-isoquinolinone derivatives as matrix metalloproteinase inhiitors |
| AU2003249540A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Fused bicyclic metalloproteinase inhibitors |
| AU2003249477A1 (en) * | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Heterobicylcic metalloproteinase inhibitors |
| CA2492019A1 (en) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Isoquinoline derivatives as matrix metalloproteinase inhibitors |
| AU2003250471A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidine-2,4-dione derivatives as matrix metalloproteinase inhibitors |
| WO2004014869A2 (en) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | 5,6-fused 3,4-dihydropyrimidine-2-one derivatives as matrix metalloproteinase inhibitors |
| WO2004014384A2 (en) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors |
| AU2003249535A1 (en) * | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | 1,6-fused uracil derivatives as matrix metalloproteinase inhibitors |
| AU2003253165A1 (en) * | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidine fused bicyclic metalloproteinase inhibitors |
| WO2004014909A1 (en) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors |
| AU2003250470A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidinone fused bicyclic metalloproteinase inhibitors |
| WO2004014365A1 (en) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Phthalimide derivatives as matrix metalloproteinase inhibitors |
| WO2004014866A1 (en) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Azaisoquinoline derivatives as matrix metalloproteinase inhibitors |
| BR0313384A (pt) | 2002-08-13 | 2005-07-12 | Warner Lambert Co | Derivados de cromona como inibidores de metaloproteinases de matriz |
| US20040142950A1 (en) * | 2003-01-17 | 2004-07-22 | Bunker Amy Mae | Amide and ester matrix metalloproteinase inhibitors |
| WO2005046683A1 (en) | 2003-10-07 | 2005-05-26 | Renovis, Inc. | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
| US20060247231A1 (en) * | 2003-12-18 | 2006-11-02 | Warner-Lambert Company Llc | Amide and ester matrix metalloproteinase inhibitors |
| TW200529812A (en) | 2003-12-26 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Benzamide derivatives |
| AU2005312721B9 (en) | 2004-12-07 | 2012-08-02 | Toyama Chemical Co., Ltd. | Novel anthranilic acid derivative or salt thereof |
| US7576099B2 (en) | 2005-02-28 | 2009-08-18 | Renovis, Inc. | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
| FI20085415A0 (fi) * | 2008-05-06 | 2008-05-06 | Raimo Tuominen | Proteiinikinaaseja muuntavia aineita |
| JP5657201B2 (ja) * | 2008-09-30 | 2015-01-21 | サンメディカル株式会社 | 酵素阻害作用または酵素阻害作用と抗菌作用とを有する歯科用組成物 |
| KR20110092309A (ko) | 2008-11-20 | 2011-08-17 | 파나세아 바이오테크 리미티드 | 신규 항균제 |
| CA2765692A1 (en) | 2009-06-26 | 2010-12-29 | Panacea Biotec Ltd. | Novel azabicyclohexanes |
| CN103012189A (zh) * | 2012-12-20 | 2013-04-03 | 天津理工大学 | 具有抗血小板聚集作用的酰胺类化合物及其制备和应用 |
| CN105693518B (zh) * | 2014-11-28 | 2018-12-14 | 天津耀宇生物技术有限公司 | 从三棱中提取邻苯二甲酸二丁酯的方法及其应用 |
| CN105884620A (zh) * | 2016-04-22 | 2016-08-24 | 东南大学 | 4-羟基-1，3苯二甲酸二酯类衍生物及其制备和应用 |
| CN116769179B (zh) * | 2023-06-21 | 2024-02-06 | 中国科学院沈阳应用生态研究所 | 一种含间苯二甲酸的配位聚合物及其制备方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5425289A (en) | 1993-10-21 | 1995-06-20 | Snap-On Incorporated | Bung tool |
| DE3931432A1 (de) | 1989-09-21 | 1991-04-04 | Hoechst Ag | Pyrimidin-4,6-dicarbonsaeurediamide, verfahren zu deren herstellung sowie verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| US5260323A (en) | 1990-06-28 | 1993-11-09 | Hoechst Aktiengesellschaft | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use |
| DE4020570A1 (de) | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung |
| EP0541042A1 (de) | 1991-11-05 | 1993-05-12 | Hoechst Aktiengesellschaft | Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
| JPH05193260A (ja) * | 1992-01-20 | 1993-08-03 | Mitsubishi Paper Mills Ltd | 感熱記録材料 |
| US6008243A (en) | 1996-10-24 | 1999-12-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
| NZ334897A (en) | 1996-12-09 | 2001-02-23 | Warner Lambert Co | Medicaments for treating and preventing heart failure and ventricular dilatation |
| AU739637B2 (en) * | 1997-07-24 | 2001-10-18 | University Of Kentucky Research Foundation, The | Phosphonated agents and their antiangiogenic and antitumorigenic use |
| JPH11199512A (ja) | 1997-10-24 | 1999-07-27 | Pfizer Prod Inc | 変形性関節症および他のｍｍｐ媒介疾患の治療のためのｍｍｐ−１３選択的阻害剤の使用 |
| UA59453C2 (uk) | 1998-08-12 | 2003-09-15 | Пфайзер Продактс Інк. | Похідні гідроксипіпеколат гідроксамової кислоти як інгібітори матричних металопротеїназ |
| WO2001005389A2 (en) * | 1999-07-16 | 2001-01-25 | G.D. Searle & Co. | N-sulfonylaminiacid derivatives as inhibitors of metalloprteinase |
| PA8498701A1 (es) | 1999-08-12 | 2002-08-26 | Pfizer Prod Inc | Pirimidina-2,4,6-trionas inhibidores de metaloproteinasas |
| US6934639B1 (en) | 2000-02-25 | 2005-08-23 | Wyeth | Methods for designing agents that interact with MMP-13 |
| EP1138680A1 (en) | 2000-03-29 | 2001-10-04 | Pfizer Products Inc. | Gem substituted sulfonyl hydroxamic acids as MMP inhibitors |
| EP1332146A2 (en) | 2000-10-26 | 2003-08-06 | Pfizer Products Inc. | Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors |
| EE200300195A (et) | 2000-10-26 | 2003-10-15 | Pfizer Products Inc. | Pürimidiin-2,4,6-trioonmetalloproteinaasi inhibiitorid |
| DE10105926B4 (de) | 2001-02-09 | 2005-06-16 | Koenig & Bauer Ag | Rollenrotationsdruckmaschine |
| JP4531996B2 (ja) | 2001-02-09 | 2010-08-25 | 株式会社エー・エム・ティー・研究所 | ポリイミドフィルム積層体 |
| DOP2002000332A (es) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| DOP2002000333A (es) * | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz |
| WO2002064571A1 (en) | 2001-02-14 | 2002-08-22 | Warner-Lambert Company Llc | Pyrimidine matrix metalloproteinase inhibitors |
| DE10160357A1 (de) | 2001-12-08 | 2003-06-18 | Aventis Pharma Gmbh | Verwendung von Pyridin-2,4-dicarbonsäurediamiden und Pyrimidin-4,6-dicarbonsäurediamiden zur selektiven Inhibierung von Kollagenasen |
| US6933298B2 (en) | 2001-12-08 | 2005-08-23 | Aventis Pharma Deutschland Gmbh | Pyridine-2,4-dicarboxylic acid diamides and pyrimidine-4,6-dicarboxylic acid diamides and the use thereof for selectively inhibiting collagenases |
-
2002
- 2002-01-24 DO DO2002000333A patent/DOP2002000333A/es unknown
- 2002-02-04 CA CA002435376A patent/CA2435376A1/en not_active Abandoned
- 2002-02-04 WO PCT/IB2002/000344 patent/WO2002064547A2/en not_active Ceased
- 2002-02-04 EP EP02716262A patent/EP1362028A2/en not_active Withdrawn
- 2002-02-04 JP JP2002564480A patent/JP2005503327A/ja active Pending
- 2002-02-04 BR BR0207201-7A patent/BR0207201A/pt not_active IP Right Cessation
- 2002-02-04 MX MXPA03006598A patent/MXPA03006598A/es active IP Right Grant
- 2002-02-11 PE PE2002000100A patent/PE20020859A1/es not_active Application Discontinuation
- 2002-02-13 AR ARP020100479A patent/AR032679A1/es not_active Application Discontinuation
- 2002-02-13 US US10/075,918 patent/US6995151B2/en not_active Expired - Fee Related
- 2002-02-13 UY UY27169A patent/UY27169A1/es not_active Application Discontinuation
- 2002-02-13 TN TNTNSN02008A patent/TNSN02008A1/fr unknown
- 2002-02-14 PA PA20028539801A patent/PA8539801A1/es unknown
-
2005
- 2005-09-29 US US11/238,502 patent/US7214712B2/en not_active Expired - Fee Related
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