JP2005052149A5 - - Google Patents
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- Publication number
- JP2005052149A5 JP2005052149A5 JP2004293969A JP2004293969A JP2005052149A5 JP 2005052149 A5 JP2005052149 A5 JP 2005052149A5 JP 2004293969 A JP2004293969 A JP 2004293969A JP 2004293969 A JP2004293969 A JP 2004293969A JP 2005052149 A5 JP2005052149 A5 JP 2005052149A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9815879.3A GB9815879D0 (en) | 1998-07-21 | 1998-07-21 | A polynucleotide |
| US10768898P | 1998-11-09 | 1998-11-09 | |
| GBGB9906712.6A GB9906712D0 (en) | 1999-03-23 | 1999-03-23 | A polynucleotide |
| US12741099P | 1999-04-01 | 1999-04-01 | |
| GBGB9909494.8A GB9909494D0 (en) | 1999-04-23 | 1999-04-23 | A plasmid |
| US13401699P | 1999-05-12 | 1999-05-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000561339A Division JP4220673B2 (ja) | 1998-07-21 | 1999-07-21 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007285560A Division JP2008109931A (ja) | 1998-07-21 | 2007-11-01 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005052149A JP2005052149A (ja) | 2005-03-03 |
| JP2005052149A5 true JP2005052149A5 (enExample) | 2005-09-29 |
Family
ID=27547316
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000561339A Expired - Lifetime JP4220673B2 (ja) | 1998-07-21 | 1999-07-21 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
| JP2004293969A Pending JP2005052149A (ja) | 1998-07-21 | 2004-10-06 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
| JP2007285560A Withdrawn JP2008109931A (ja) | 1998-07-21 | 2007-11-01 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
| JP2008305611A Withdrawn JP2009102331A (ja) | 1998-07-21 | 2008-11-28 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000561339A Expired - Lifetime JP4220673B2 (ja) | 1998-07-21 | 1999-07-21 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007285560A Withdrawn JP2008109931A (ja) | 1998-07-21 | 2007-11-01 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
| JP2008305611A Withdrawn JP2009102331A (ja) | 1998-07-21 | 2008-11-28 | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
Country Status (8)
| Country | Link |
|---|---|
| EP (2) | EP2348118A1 (enExample) |
| JP (4) | JP4220673B2 (enExample) |
| KR (3) | KR100795626B1 (enExample) |
| CN (1) | CN100365127C (enExample) |
| AU (1) | AU771111B2 (enExample) |
| CA (1) | CA2333852C (enExample) |
| MX (1) | MXPA01000830A (enExample) |
| WO (1) | WO2000005393A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU9006701A (en) | 2000-09-20 | 2002-04-02 | Cobra Therapeutics Ltd | Polynucleotide |
| ES2330201T3 (es) | 2001-01-26 | 2009-12-07 | Selexis S.A. | Regiones de union a la matriz y metodos para el uso de las mismas. |
| AU2002242872B2 (en) | 2001-04-05 | 2006-12-14 | Emd Millipore Corporation | Improved gene expression |
| US7812148B2 (en) | 2001-04-05 | 2010-10-12 | Millipore Corporation | Vectors comprising CpG islands without position effect varigation and having increased expression |
| KR100955756B1 (ko) * | 2001-04-05 | 2010-04-30 | 밀리포어 코포레이션 | 개량된 유전자 발현 |
| BR0209989A (pt) | 2001-05-30 | 2005-04-12 | Chromos Molecular Systems Inc | Plataformas baseadas em cromossomas |
| US20040161817A1 (en) * | 2001-06-04 | 2004-08-19 | Corixa Corporation | Compositions and methods for high-level, large-scale production of recombinant proteins |
| ES2344070T3 (es) | 2001-07-04 | 2010-08-17 | Chromagenics B.V. | Secuencias de adn con actividad anti-represora. |
| EP1465993B1 (en) | 2002-01-09 | 2009-09-23 | Minos Biosystems Limited | Inducible transposition in transgenic organism using transposon vector |
| NZ537073A (en) | 2002-06-14 | 2006-08-31 | Chromagenics B | A method for simultaneous production of multiple proteins; vectors and cells for use therein |
| AU2003243059A1 (en) | 2002-06-14 | 2003-12-31 | Chromagenics B.V. | Use of repression blocking sequences in methods for enhancing gene expression |
| ES2373549T3 (es) | 2002-12-18 | 2012-02-06 | Chromagenics B.V. | Método para mejorar la producción de proteínas. |
| AU2003290453A1 (en) | 2002-12-20 | 2004-07-14 | Chromagenics B.V. | Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors |
| ES2345335T3 (es) | 2003-02-01 | 2010-09-21 | Millipore Corporation | Elementos geneticos mejorados que proporcionan altos niveles de expresion. |
| EP1959011B1 (en) | 2003-10-24 | 2012-03-28 | Selexis S.A. | High efficiency gene transfer and expression in mammalian cells by a multiple transfection procedure of matrix attachment region sequences |
| ATE546531T1 (de) * | 2003-12-31 | 2012-03-15 | Kalobios Inc | Transaktivierungssystem für säugerzellen |
| KR20070038556A (ko) | 2004-07-20 | 2007-04-10 | 심포젠 에이/에스 | 항-ｒｈｅｓｕｓ ｄ 재조합 폴리클로날 항체 및 이의 제조방법 |
| US8039230B2 (en) | 2004-11-08 | 2011-10-18 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US8999667B2 (en) | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| AU2005300503B2 (en) | 2004-11-08 | 2010-12-16 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20060172382A1 (en) | 2004-11-08 | 2006-08-03 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| GB0504587D0 (en) | 2005-03-05 | 2005-04-13 | Ml Lab Plc | Vectors comprising guinea pig CMV regulatory elements |
| GB0509965D0 (en) | 2005-05-17 | 2005-06-22 | Ml Lab Plc | Improved expression elements |
| WO2007081336A1 (en) * | 2006-01-13 | 2007-07-19 | Five Prime Therapeutics, Inc. | Mammalian vectors for high-level expression of recombinant proteins |
| US7968700B2 (en) | 2006-03-20 | 2011-06-28 | Chromagenics B.V. | Expression augmenting DNA fragments, use thereof, and methods for finding thereof |
| EP2118270A2 (en) * | 2007-01-08 | 2009-11-18 | Millipore Corporation | Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants |
| CN104531699B (zh) * | 2014-10-09 | 2017-03-15 | 河南农业大学 | 一种增强外源基因表达的猪的ucoe调控元件片段 |
| EP3234128B1 (en) * | 2014-12-16 | 2025-06-18 | Garvan Institute of Medical Research | Sequencing controls |
| CN110431227A (zh) * | 2017-03-19 | 2019-11-08 | 应用干细胞有限公司 | 新型整合位点及其用途 |
| AU2018249444A1 (en) | 2017-04-03 | 2019-10-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for multiplexed quantitative analysis of cell lineages |
| EP3720958A1 (en) * | 2017-12-07 | 2020-10-14 | Integrity Biosolutions, LLC | Engineered ubiquitous chromatin opening elements and uses thereof |
| CN112135909A (zh) * | 2018-05-24 | 2020-12-25 | 国立大学法人北海道大学 | 新载体及其应用 |
| BR112021002779A2 (pt) | 2018-08-15 | 2021-05-04 | Illumina, Inc. | composições e métodos para melhorar o enriquecimento de bibliotecas |
| AU2019354390A1 (en) * | 2018-10-02 | 2021-04-01 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for multiplexed quantitative analysis of cell lineages |
| US20220193266A1 (en) * | 2019-04-30 | 2022-06-23 | Chan Zuckerberg Biohub, Inc. | A novel chromatin-opening element for stable long term gene expression |
| CN112575031B (zh) * | 2019-09-29 | 2023-04-07 | 新乡医学院 | 一种遍在染色质开放表达元件、重组表达载体、表达系统及其制备方法、应用 |
| CN116574735B (zh) * | 2023-07-03 | 2023-11-10 | 艾米能斯(苏州)生物科技有限公司 | 一种多核苷酸及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166320A (en) | 1987-04-22 | 1992-11-24 | University Of Connecticut | Carrier system and method for the introduction of genes into mammalian cells |
| GB8718779D0 (en) | 1987-08-07 | 1987-09-16 | Grosveld F G | Dna sequence & expression vector |
| AU635844B2 (en) | 1989-11-06 | 1993-04-01 | Cell Genesys, Inc. | Production of proteins using homologous recombination |
| JP3222461B2 (ja) | 1990-05-18 | 2001-10-29 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規タンパク質―ポリカチオン結合体 |
| AU7906691A (en) | 1990-05-23 | 1991-12-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Adeno-associated virus (aav)-based eucaryotic vectors |
| GB9109928D0 (en) | 1991-05-08 | 1991-07-03 | Interox Chemicals Ltd | Thickened compositions |
| US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| CA2131620A1 (en) | 1992-03-20 | 1993-09-30 | Louis C. Smith | A dna transporter system and method of use |
| US5583009A (en) | 1992-12-08 | 1996-12-10 | University Of Washington | Method of preparing recombinant proteins in transgenic animals containing metallothionein gene elements that bestow tissue-independent copy number-dependent, position-indepedent gene expression |
| US5578475A (en) | 1993-07-12 | 1996-11-26 | Life Technologies, Inc. | Composition and methods for transfecting eukaryotic cells |
| AU6011496A (en) | 1995-06-08 | 1997-01-09 | Therexsys Limited | Improved pharmaceutical compositions for gene therapy |
| DE69704206T2 (de) | 1996-08-16 | 2001-08-30 | Medical Research Council, London | Selbst-replizierende episomale expressionsvektoren, welche gewebespezifische expression vermitteln |
| DE19651443A1 (de) | 1996-12-11 | 1998-06-18 | Hoechst Ag | Selbstverstärkende, pharmakologisch kontrollierbare Expressionssysteme |
| EP1007549B1 (en) | 1997-02-12 | 2006-12-27 | Innovata Plc | Compositions and methods for highly efficient transfection |
-
1999
- 1999-07-21 JP JP2000561339A patent/JP4220673B2/ja not_active Expired - Lifetime
- 1999-07-21 CN CNB998111554A patent/CN100365127C/zh not_active Expired - Lifetime
- 1999-07-21 CA CA002333852A patent/CA2333852C/en not_active Expired - Lifetime
- 1999-07-21 AU AU50534/99A patent/AU771111B2/en not_active Expired
- 1999-07-21 EP EP10183981A patent/EP2348118A1/en not_active Withdrawn
- 1999-07-21 KR KR1020017000883A patent/KR100795626B1/ko not_active Expired - Lifetime
- 1999-07-21 WO PCT/GB1999/002357 patent/WO2000005393A2/en not_active Ceased
- 1999-07-21 EP EP99934910A patent/EP1098986B1/en not_active Expired - Lifetime
- 1999-07-21 MX MXPA01000830A patent/MXPA01000830A/es not_active IP Right Cessation
-
2004
- 2004-10-06 JP JP2004293969A patent/JP2005052149A/ja active Pending
-
2007
- 2007-10-15 KR KR1020070103583A patent/KR20070108336A/ko not_active Ceased
- 2007-11-01 JP JP2007285560A patent/JP2008109931A/ja not_active Withdrawn
-
2008
- 2008-11-28 JP JP2008305611A patent/JP2009102331A/ja not_active Withdrawn
-
2009
- 2009-09-30 KR KR1020090093097A patent/KR20090117675A/ko not_active Ceased