JP2005052149A5 - - Google Patents

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Publication number
JP2005052149A5
JP2005052149A5 JP2004293969A JP2004293969A JP2005052149A5 JP 2005052149 A5 JP2005052149 A5 JP 2005052149A5 JP 2004293969 A JP2004293969 A JP 2004293969A JP 2004293969 A JP2004293969 A JP 2004293969A JP 2005052149 A5 JP2005052149 A5 JP 2005052149A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004293969A
Other languages
Japanese (ja)
Other versions
JP2005052149A (ja
Filing date
Publication date
Priority claimed from GBGB9815879.3A external-priority patent/GB9815879D0/en
Priority claimed from GBGB9906712.6A external-priority patent/GB9906712D0/en
Priority claimed from GBGB9909494.8A external-priority patent/GB9909494D0/en
Application filed filed Critical
Publication of JP2005052149A publication Critical patent/JP2005052149A/ja
Publication of JP2005052149A5 publication Critical patent/JP2005052149A5/ja
Pending legal-status Critical Current

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JP2004293969A 1998-07-21 2004-10-06 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド Pending JP2005052149A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9815879.3A GB9815879D0 (en) 1998-07-21 1998-07-21 A polynucleotide
US10768898P 1998-11-09 1998-11-09
GBGB9906712.6A GB9906712D0 (en) 1999-03-23 1999-03-23 A polynucleotide
US12741099P 1999-04-01 1999-04-01
GBGB9909494.8A GB9909494D0 (en) 1999-04-23 1999-04-23 A plasmid
US13401699P 1999-05-12 1999-05-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2000561339A Division JP4220673B2 (ja) 1998-07-21 1999-07-21 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007285560A Division JP2008109931A (ja) 1998-07-21 2007-11-01 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Publications (2)

Publication Number Publication Date
JP2005052149A JP2005052149A (ja) 2005-03-03
JP2005052149A5 true JP2005052149A5 (enExample) 2005-09-29

Family

ID=27547316

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2000561339A Expired - Lifetime JP4220673B2 (ja) 1998-07-21 1999-07-21 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2004293969A Pending JP2005052149A (ja) 1998-07-21 2004-10-06 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2007285560A Withdrawn JP2008109931A (ja) 1998-07-21 2007-11-01 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2008305611A Withdrawn JP2009102331A (ja) 1998-07-21 2008-11-28 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2000561339A Expired - Lifetime JP4220673B2 (ja) 1998-07-21 1999-07-21 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007285560A Withdrawn JP2008109931A (ja) 1998-07-21 2007-11-01 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2008305611A Withdrawn JP2009102331A (ja) 1998-07-21 2008-11-28 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Country Status (8)

Country Link
EP (2) EP2348118A1 (enExample)
JP (4) JP4220673B2 (enExample)
KR (3) KR100795626B1 (enExample)
CN (1) CN100365127C (enExample)
AU (1) AU771111B2 (enExample)
CA (1) CA2333852C (enExample)
MX (1) MXPA01000830A (enExample)
WO (1) WO2000005393A2 (enExample)

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AU9006701A (en) * 2000-09-20 2002-04-02 Cobra Therapeutics Ltd Polynucleotide
EP1395669B1 (en) 2001-01-26 2009-07-22 Selexis S.A. Matrix attachment regions and methods for use thereof
US7812148B2 (en) 2001-04-05 2010-10-12 Millipore Corporation Vectors comprising CpG islands without position effect varigation and having increased expression
ES2339428T3 (es) * 2001-04-05 2010-05-20 Millipore Corporation Expresion de genes mejorada.
ES2387951T3 (es) * 2001-04-05 2012-10-04 Emd Millipore Corporation Expresión génica mejorada
CA2441937A1 (en) 2001-05-30 2002-12-05 Chromos Molecular Systems, Inc. Chromosome-based platforms
US20040161817A1 (en) * 2001-06-04 2004-08-19 Corixa Corporation Compositions and methods for high-level, large-scale production of recombinant proteins
EP1806407B1 (en) 2001-07-04 2010-05-05 Chromagenics B.V. DNA sequences having anti-repressor activity
CN1612931A (zh) 2002-01-09 2005-05-04 米诺斯生物系统有限公司 遗传操作方法
EP1513936A2 (en) 2002-06-14 2005-03-16 Chromagenics B.V. Use of repression blocking sequences in methods for enhancing gene expression
DK1513937T3 (da) 2002-06-14 2011-05-16 Chromagenics Bv Fremgangsmåde til den samtidige produktion af multiple proteiner; vektorer og celler til anvendelse derved
CA2510179C (en) 2002-12-18 2013-04-23 Chromagenics B.V. A method for improving protein production
ATE354645T1 (de) 2002-12-20 2007-03-15 Chromagenics Bv Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können
US9057079B2 (en) 2003-02-01 2015-06-16 Emd Millipore Corporation Expression elements
PL1959011T3 (pl) 2003-10-24 2012-07-31 Selexis Sa Wysokowydajny transfer genu i ekspresja w komórkach ssaczych przez procedurę wielokrotnej transfekcji sekwencji regionu przylegania do macierzy
EP1702071B1 (en) * 2003-12-31 2012-02-22 Kalobios Inc. Transactivation system for mammalian cells
MX2007000644A (es) 2004-07-20 2007-03-28 Symphogen As Anticuerpo policlonal recombinante anti-rhesus d y metodos de fabricacion.
US8999667B2 (en) 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
CN101090968B (zh) 2004-11-08 2011-10-26 科罗迈吉尼科斯公司 高水平表达蛋白质的宿主细胞的选择
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
PL1809750T3 (pl) 2004-11-08 2012-08-31 Chromagenics Bv Selekcja komórki gospodarza eksprymującej białko na wysokich poziomach
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
GB0504587D0 (en) 2005-03-05 2005-04-13 Ml Lab Plc Vectors comprising guinea pig CMV regulatory elements
GB0509965D0 (en) * 2005-05-17 2005-06-22 Ml Lab Plc Improved expression elements
WO2007081336A1 (en) * 2006-01-13 2007-07-19 Five Prime Therapeutics, Inc. Mammalian vectors for high-level expression of recombinant proteins
US7968700B2 (en) 2006-03-20 2011-06-28 Chromagenics B.V. Expression augmenting DNA fragments, use thereof, and methods for finding thereof
US8058027B2 (en) 2007-01-08 2011-11-15 Millipore Corporation Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants
CN104531699B (zh) * 2014-10-09 2017-03-15 河南农业大学 一种增强外源基因表达的猪的ucoe调控元件片段
EP4589006A3 (en) * 2014-12-16 2025-08-13 Garvan Institute of Medical Research Sequencing controls
WO2018175153A1 (en) * 2017-03-19 2018-09-27 Applied Stemcell, Inc. Novel integration sites and uses thereof
EP3607057A4 (en) 2017-04-03 2020-12-09 The Board of Trustees of the Leland Stanford Junior University COMPOSITIONS AND METHODS FOR MULTIPLEXED QUANTITATIVE ANALYSIS OF CELLULAR LINES
EP3720958A1 (en) * 2017-12-07 2020-10-14 Integrity Biosolutions, LLC Engineered ubiquitous chromatin opening elements and uses thereof
JP7264353B2 (ja) * 2018-05-24 2023-04-25 国立大学法人北海道大学 新規ベクターおよびその利用
CA3109238A1 (en) 2018-08-15 2020-02-20 Illumina, Inc. Compositions and methods for improving library enrichment
EP3861105A4 (en) * 2018-10-02 2022-06-29 The Board of Trustees of the Leland Stanford Junior University Compositions and methods for multiplexed quantitative analysis of cell lineages
US12611470B2 (en) 2019-04-30 2026-04-28 Cz Biohub Sf, Llc Chromatin-opening element for stable long term gene expression
CN112575031B (zh) * 2019-09-29 2023-04-07 新乡医学院 一种遍在染色质开放表达元件、重组表达载体、表达系统及其制备方法、应用
CN116574735B (zh) * 2023-07-03 2023-11-10 艾米能斯(苏州)生物科技有限公司 一种多核苷酸及其应用

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US5166320A (en) 1987-04-22 1992-11-24 University Of Connecticut Carrier system and method for the introduction of genes into mammalian cells
GB8718779D0 (en) 1987-08-07 1987-09-16 Grosveld F G Dna sequence & expression vector
ATE174058T1 (de) 1989-11-06 1998-12-15 Cell Genesys Inc Herstellung von proteinen mittels homologer rekombination
ATE126442T1 (de) 1990-05-18 1995-09-15 Boehringer Ingelheim Int Neue protein-polykation-konjugate.
AU7906691A (en) 1990-05-23 1991-12-10 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Adeno-associated virus (aav)-based eucaryotic vectors
GB9109928D0 (en) 1991-05-08 1991-07-03 Interox Chemicals Ltd Thickened compositions
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
AU671450B2 (en) 1992-03-20 1996-08-29 Baylor College Of Medicine A DNA transporter system and method of use
US5583009A (en) 1992-12-08 1996-12-10 University Of Washington Method of preparing recombinant proteins in transgenic animals containing metallothionein gene elements that bestow tissue-independent copy number-dependent, position-indepedent gene expression
US5578475A (en) 1993-07-12 1996-11-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
JP2002514892A (ja) 1995-06-08 2002-05-21 コブラ セラピューティクス リミテッド 遺伝子治療における合成ウイルス様粒子の使用
DE69704206T2 (de) 1996-08-16 2001-08-30 Medical Research Council, London Selbst-replizierende episomale expressionsvektoren, welche gewebespezifische expression vermitteln
DE19651443A1 (de) * 1996-12-11 1998-06-18 Hoechst Ag Selbstverstärkende, pharmakologisch kontrollierbare Expressionssysteme
ATE349465T1 (de) 1997-02-12 2007-01-15 Innovata Plc Zusammensetzungen sowie verfahren zur hocheffizienten transfektion

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