JP2005052149A5 - - Google Patents

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Publication number
JP2005052149A5
JP2005052149A5 JP2004293969A JP2004293969A JP2005052149A5 JP 2005052149 A5 JP2005052149 A5 JP 2005052149A5 JP 2004293969 A JP2004293969 A JP 2004293969A JP 2004293969 A JP2004293969 A JP 2004293969A JP 2005052149 A5 JP2005052149 A5 JP 2005052149A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004293969A
Other languages
Japanese (ja)
Other versions
JP2005052149A (ja
Filing date
Publication date
Priority claimed from GBGB9815879.3A external-priority patent/GB9815879D0/en
Priority claimed from GBGB9906712.6A external-priority patent/GB9906712D0/en
Priority claimed from GBGB9909494.8A external-priority patent/GB9909494D0/en
Application filed filed Critical
Publication of JP2005052149A publication Critical patent/JP2005052149A/ja
Publication of JP2005052149A5 publication Critical patent/JP2005052149A5/ja
Pending legal-status Critical Current

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JP2004293969A 1998-07-21 2004-10-06 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド Pending JP2005052149A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9815879.3A GB9815879D0 (en) 1998-07-21 1998-07-21 A polynucleotide
US10768898P 1998-11-09 1998-11-09
GBGB9906712.6A GB9906712D0 (en) 1999-03-23 1999-03-23 A polynucleotide
US12741099P 1999-04-01 1999-04-01
GBGB9909494.8A GB9909494D0 (en) 1999-04-23 1999-04-23 A plasmid
US13401699P 1999-05-12 1999-05-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2000561339A Division JP4220673B2 (ja) 1998-07-21 1999-07-21 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007285560A Division JP2008109931A (ja) 1998-07-21 2007-11-01 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Publications (2)

Publication Number Publication Date
JP2005052149A JP2005052149A (ja) 2005-03-03
JP2005052149A5 true JP2005052149A5 (enExample) 2005-09-29

Family

ID=27547316

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2000561339A Expired - Lifetime JP4220673B2 (ja) 1998-07-21 1999-07-21 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2004293969A Pending JP2005052149A (ja) 1998-07-21 2004-10-06 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2007285560A Withdrawn JP2008109931A (ja) 1998-07-21 2007-11-01 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2008305611A Withdrawn JP2009102331A (ja) 1998-07-21 2008-11-28 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2000561339A Expired - Lifetime JP4220673B2 (ja) 1998-07-21 1999-07-21 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007285560A Withdrawn JP2008109931A (ja) 1998-07-21 2007-11-01 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド
JP2008305611A Withdrawn JP2009102331A (ja) 1998-07-21 2008-11-28 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド

Country Status (8)

Country Link
EP (2) EP2348118A1 (enExample)
JP (4) JP4220673B2 (enExample)
KR (3) KR100795626B1 (enExample)
CN (1) CN100365127C (enExample)
AU (1) AU771111B2 (enExample)
CA (1) CA2333852C (enExample)
MX (1) MXPA01000830A (enExample)
WO (1) WO2000005393A2 (enExample)

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KR100996016B1 (ko) 2000-09-20 2010-11-22 밀리포어 코포레이션 폴리뉴클레오티드
DK1395669T3 (da) 2001-01-26 2009-11-16 Selexis Sa Matriks bindingsregioner og fremgangsmåder til anvendelse af disse
CN102206633A (zh) * 2001-04-05 2011-10-05 密理博公司 改进的基因表达
WO2002081677A2 (en) * 2001-04-05 2002-10-17 Ml Laboratories Plc Improved gene expression
US7812148B2 (en) 2001-04-05 2010-10-12 Millipore Corporation Vectors comprising CpG islands without position effect varigation and having increased expression
JP4489424B2 (ja) 2001-05-30 2010-06-23 グラクソ グループ リミテッド 染色体に基くプラットホーム
WO2002099070A2 (en) * 2001-06-04 2002-12-12 Corixa Corporation Compositions and methods for high-level, large-scale production of recombinant proteins
DE60237048D1 (de) 2001-07-04 2010-08-26 Chromagenics Bv DNS-Sequenzen mit Anti-Repressor-Aktivität
ATE443762T1 (de) 2002-01-09 2009-10-15 Minos Biosystems Ltd Induktierbare transposition beim transgenen organismus mit transposon-vektor
CA2489475C (en) 2002-06-14 2011-03-29 Chromagenics B.V. A method for simultaneous production of multiple proteins; vectors and cells for use therein
WO2003106674A2 (en) 2002-06-14 2003-12-24 Chromagenics B.V. Means and methods for regulating gene expression
DK1573058T3 (da) 2002-12-18 2012-01-16 Chromagenics Bv Fremgangsmåde til forbedring af proteinproduktion
DK1572994T3 (da) 2002-12-20 2007-05-29 Chromagenics Bv Midler og fremgangsmåder til fremstilling af en protein gennem chromatinåbnere, som kan göre chromatin mere tilgængeligt for transkriptionsfaktorer
ATE471988T1 (de) 2003-02-01 2010-07-15 Millipore Corp Verbesserte genetische elemente für eine erhöhte genexpression
KR101269656B1 (ko) 2003-10-24 2013-05-30 셀렉시스 에스. 에이. Ｍａｒ 서열의 복합 트랜스펙션 방법에 의한 포유동물 세포에서의 고효율 유전자 전달 및 발현
EP1702071B1 (en) * 2003-12-31 2012-02-22 Kalobios Inc. Transactivation system for mammalian cells
JP4926054B2 (ja) 2004-07-20 2012-05-09 シムフォゲン・アクティーゼルスカブ 抗−ＲｈＤ組換えポリクローナル抗体及び製造方法
US8999667B2 (en) 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
NZ553700A (en) 2004-11-08 2010-09-30 Chromagenics Bv Selection of host cells expressing protein at high levels using a selectable marker with a non-optimal start codon
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
BRPI0517380A (pt) 2004-11-08 2008-10-07 Chromagenics Bv molécula de dna, cassete de expressão, célula hospedeira, e, métodos para gerar uma célula hospedeira que expressa um polipeptìdeo de interesse e para produzir um polipeptìdeo de interesse
GB0504587D0 (en) 2005-03-05 2005-04-13 Ml Lab Plc Vectors comprising guinea pig CMV regulatory elements
GB0509965D0 (en) * 2005-05-17 2005-06-22 Ml Lab Plc Improved expression elements
WO2007081336A1 (en) * 2006-01-13 2007-07-19 Five Prime Therapeutics, Inc. Mammalian vectors for high-level expression of recombinant proteins
EP1996705B1 (en) 2006-03-20 2011-08-31 ChromaGenics B.V. Expression augmenting dna fragments, use thereof, and methods for finding thereof
WO2008085962A2 (en) * 2007-01-08 2008-07-17 Millipore Corporation Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants
CN104531699B (zh) * 2014-10-09 2017-03-15 河南农业大学 一种增强外源基因表达的猪的ucoe调控元件片段
EP4589006A3 (en) * 2014-12-16 2025-08-13 Garvan Institute of Medical Research Sequencing controls
US11959093B2 (en) 2017-03-19 2024-04-16 Applied Stemcell, Inc. Integration sites and uses thereof
US10801021B2 (en) 2017-04-03 2020-10-13 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for multiplexed quantitative analysis of cell lineages
WO2019113378A1 (en) * 2017-12-07 2019-06-13 Integrity Biosolutions, Llc Engineered ubiquitous chromatin opening elements and uses thereof
KR102873620B1 (ko) * 2018-05-24 2025-10-21 국립대학법인 홋가이도 다이가쿠 신규 벡터 및 그 이용
JP7431802B2 (ja) 2018-08-15 2024-02-15 イルミナ インコーポレイテッド ライブラリー富化を改善するための組成物および方法
US20220304285A1 (en) * 2018-10-02 2022-09-29 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for multiplexed quantitative analysis of cell lineages
WO2020223160A1 (en) * 2019-04-30 2020-11-05 Chan Zuckerberg Biohub, Inc. A novel chromatin-opening element for stable long term gene expression
CN112575031B (zh) * 2019-09-29 2023-04-07 新乡医学院 一种遍在染色质开放表达元件、重组表达载体、表达系统及其制备方法、应用
CN116574735B (zh) * 2023-07-03 2023-11-10 艾米能斯(苏州)生物科技有限公司 一种多核苷酸及其应用

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US5166320A (en) 1987-04-22 1992-11-24 University Of Connecticut Carrier system and method for the introduction of genes into mammalian cells
GB8718779D0 (en) 1987-08-07 1987-09-16 Grosveld F G Dna sequence & expression vector
SG88714A1 (en) 1989-11-06 2002-05-21 Cell Genesys Inc Production of proteins using homologous recombination
WO1991017773A2 (de) 1990-05-18 1991-11-28 Boehringer Ingelheim International Gmbh Neue protein-polykation-konjugate
AU7906691A (en) 1990-05-23 1991-12-10 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Adeno-associated virus (aav)-based eucaryotic vectors
GB9109928D0 (en) 1991-05-08 1991-07-03 Interox Chemicals Ltd Thickened compositions
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
JPH07505283A (ja) 1992-03-20 1995-06-15 ベイラー・カレッジ・オブ・メディシン Ｄｎａトランスポーター系および使用方法
US5583009A (en) 1992-12-08 1996-12-10 University Of Washington Method of preparing recombinant proteins in transgenic animals containing metallothionein gene elements that bestow tissue-independent copy number-dependent, position-indepedent gene expression
WO1995002698A1 (en) 1993-07-12 1995-01-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
WO1996041606A2 (en) 1995-06-08 1996-12-27 Therexsys Limited Improved pharmaceutical compositions for gene therapy
ATE199570T1 (de) 1996-08-16 2001-03-15 Medical Res Council Selbst-replizierende episomale expressionsvektoren, welche gewebespezifische expression vermitteln
DE19651443A1 (de) * 1996-12-11 1998-06-18 Hoechst Ag Selbstverstärkende, pharmakologisch kontrollierbare Expressionssysteme
ATE349465T1 (de) 1997-02-12 2007-01-15 Innovata Plc Zusammensetzungen sowie verfahren zur hocheffizienten transfektion

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