JP2004536633A5 - - Google Patents
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- JP2004536633A5 JP2004536633A5 JP2002591047A JP2002591047A JP2004536633A5 JP 2004536633 A5 JP2004536633 A5 JP 2004536633A5 JP 2002591047 A JP2002591047 A JP 2002591047A JP 2002591047 A JP2002591047 A JP 2002591047A JP 2004536633 A5 JP2004536633 A5 JP 2004536633A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkylene
- alkyl
- formula
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- -1 hydroxy, sulfo Chemical group 0.000 claims 27
- 229910052739 hydrogen Inorganic materials 0.000 claims 18
- 238000000034 method Methods 0.000 claims 18
- 239000001257 hydrogen Substances 0.000 claims 15
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 10
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 8
- 239000013590 bulk material Substances 0.000 claims 6
- RWRIWBAIICGTTQ-UHFFFAOYSA-N difluoromethane Chemical compound FCF RWRIWBAIICGTTQ-UHFFFAOYSA-N 0.000 claims 6
- 229920001477 hydrophilic polymer Polymers 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 5
- 125000006850 spacer group Chemical group 0.000 claims 5
- 125000004406 C3-C8 cycloalkylene group Chemical group 0.000 claims 4
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 4
- 239000000463 material Substances 0.000 claims 4
- 239000003505 polymerization initiator Substances 0.000 claims 4
- 238000006116 polymerization reaction Methods 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000002947 alkylene group Chemical group 0.000 claims 3
- 239000002131 composite material Substances 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 210000004087 cornea Anatomy 0.000 claims 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 3
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims 2
- 150000001450 anions Chemical class 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 239000003999 initiator Substances 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 150000002482 oligosaccharides Polymers 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims 1
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 claims 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- 229920001287 Chondroitin sulfate Polymers 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 1
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 claims 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 1
- 102000015636 Oligopeptides Human genes 0.000 claims 1
- 108010038807 Oligopeptides Proteins 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 229940059329 chondroitin sulfate Drugs 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 229960002086 dextran Drugs 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 229920000669 heparin Polymers 0.000 claims 1
- 229960002897 heparin Drugs 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 229960002591 hydroxyproline Drugs 0.000 claims 1
- 125000002962 imidazol-1-yl group Chemical group [*]N1C([H])=NC([H])=C1[H] 0.000 claims 1
- 125000002883 imidazolyl group Chemical group 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 125000001041 indolyl group Chemical group 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 125000001261 isocyanato group Chemical group *N=C=O 0.000 claims 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 claims 1
- 125000001810 isothiocyanato group Chemical group *N=C=S 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- HZVOZRGWRWCICA-UHFFFAOYSA-N methanediyl Chemical compound [CH2] HZVOZRGWRWCICA-UHFFFAOYSA-N 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 claims 1
- 229920002401 polyacrylamide Polymers 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 230000000379 polymerizing effect Effects 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 239000007870 radical polymerization initiator Substances 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000005717 substituted cycloalkylene group Chemical group 0.000 claims 1
- 125000004964 sulfoalkyl group Chemical group 0.000 claims 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
- GBXQPDCOMJJCMJ-UHFFFAOYSA-M trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;bromide Chemical compound [Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C GBXQPDCOMJJCMJ-UHFFFAOYSA-M 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01810503 | 2001-05-21 | ||
| PCT/EP2002/005495 WO2002094331A1 (en) | 2001-05-21 | 2002-05-17 | Bottle-brush type coatings with entangled hydrophilic polymer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004536633A JP2004536633A (ja) | 2004-12-09 |
| JP2004536633A5 true JP2004536633A5 (https=) | 2005-12-22 |
Family
ID=8183924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002591047A Pending JP2004536633A (ja) | 2001-05-21 | 2002-05-17 | 絡み合った親水性ポリマーを有するボトル−ブラシ型コーティング |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6835410B2 (https=) |
| EP (1) | EP1395302B1 (https=) |
| JP (1) | JP2004536633A (https=) |
| AT (1) | ATE288289T1 (https=) |
| DE (1) | DE60202866T2 (https=) |
| WO (1) | WO2002094331A1 (https=) |
Families Citing this family (65)
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| JP2003063932A (ja) * | 2001-08-24 | 2003-03-05 | Catalysts & Chem Ind Co Ltd | 化粧料用改質無機微粒子およびそれを配合した化粧料 |
| TW200407367A (en) * | 2001-11-13 | 2004-05-16 | Novartis Ag | Method for modifying the surface of biomedical articles |
| US8172395B2 (en) | 2002-12-03 | 2012-05-08 | Novartis Ag | Medical devices having antimicrobial coatings thereon |
| US7727581B2 (en) * | 2004-03-17 | 2010-06-01 | Essilor International Compagnie Generale D' Optique | Process for applying a coating on an optical lens face and implementation system |
| DE102004057155B4 (de) * | 2004-11-26 | 2007-02-01 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur chemischen Funktionalisierung von Oberflächen durch Plasmapolymerisation |
| CA2641021C (en) | 2006-02-01 | 2015-07-07 | Hollister Incorporated | Methods of applying a hydrophilic coating to a substrate, and substrates having a hydrophilic coating |
| US8795782B2 (en) | 2006-08-18 | 2014-08-05 | Commonwealth Scientific And Industrial Research Organisation | Polymeric coatings and methods for forming them |
| EP2052045A4 (en) | 2006-08-18 | 2012-09-12 | Commw Scient Ind Res Org | POLYMERIC COATINGS AND METHODS FOR FORMING SAME |
| JP5272353B2 (ja) * | 2007-08-27 | 2013-08-28 | 日油株式会社 | 熱可塑性樹脂組成物 |
| KR101160204B1 (ko) * | 2007-08-27 | 2012-07-03 | 니치유 가부시키가이샤 | 열가소성 수지 조성물 |
| JP5374852B2 (ja) * | 2007-10-17 | 2013-12-25 | 日油株式会社 | 結晶性熱可塑性樹脂組成物 |
| US20090111942A1 (en) * | 2007-10-25 | 2009-04-30 | Bausch & Lomb Incorporated | Method for Making Surface Modified Biomedical Devices |
| JP5253851B2 (ja) * | 2008-03-18 | 2013-07-31 | 株式会社シード | 眼用レンズ及び眼用レンズの製造方法 |
| TWI507183B (zh) * | 2009-09-04 | 2015-11-11 | Alcon Inc | 具晶體間混濁化抗性之眼內晶體 |
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| JP2013235034A (ja) * | 2012-05-02 | 2013-11-21 | Menicon Co Ltd | 表面処理樹脂成形体の製造方法及び表面処理樹脂成形体 |
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| WO2014039495A1 (en) | 2012-09-05 | 2014-03-13 | University Of Miami | Novel keratoprosthesis, and system and method of corneal repair using same |
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| US9486311B2 (en) | 2013-02-14 | 2016-11-08 | Shifamed Holdings, Llc | Hydrophilic AIOL with bonding |
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| CN114366858B (zh) * | 2021-12-31 | 2023-07-25 | 东华大学 | 一种具有抗菌防痰栓功能的气管导管及其制备方法 |
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| TW473488B (en) | 1998-04-30 | 2002-01-21 | Novartis Ag | Composite materials, biomedical articles formed thereof and process for their manufacture |
| US6087415A (en) * | 1998-06-11 | 2000-07-11 | Johnson & Johnson Vision Care, Inc. | Biomedical devices with hydrophilic coatings |
| US20010036556A1 (en) * | 1998-10-20 | 2001-11-01 | James S. Jen | Coatings for biomedical devices |
| US6440571B1 (en) * | 1999-05-20 | 2002-08-27 | Bausch & Lomb Incorporated | Surface treatment of silicone medical devices with reactive hydrophilic polymers |
| EP1095966B1 (en) | 1999-10-27 | 2006-01-11 | Novartis AG | Process for the modification of a material surface |
-
2002
- 2002-05-09 US US10/142,300 patent/US6835410B2/en not_active Expired - Lifetime
- 2002-05-17 JP JP2002591047A patent/JP2004536633A/ja active Pending
- 2002-05-17 AT AT02727603T patent/ATE288289T1/de not_active IP Right Cessation
- 2002-05-17 DE DE60202866T patent/DE60202866T2/de not_active Expired - Lifetime
- 2002-05-17 EP EP02727603A patent/EP1395302B1/en not_active Expired - Lifetime
- 2002-05-17 WO PCT/EP2002/005495 patent/WO2002094331A1/en not_active Ceased
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