JP2004521607A5 - - Google Patents
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- Publication number
- JP2004521607A5 JP2004521607A5 JP2002500722A JP2002500722A JP2004521607A5 JP 2004521607 A5 JP2004521607 A5 JP 2004521607A5 JP 2002500722 A JP2002500722 A JP 2002500722A JP 2002500722 A JP2002500722 A JP 2002500722A JP 2004521607 A5 JP2004521607 A5 JP 2004521607A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- acid sequence
- amino acid
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 24
- 125000003275 alpha amino acid group Chemical group 0.000 claims 23
- 229920001184 polypeptide Polymers 0.000 claims 18
- 102000004196 processed proteins & peptides Human genes 0.000 claims 18
- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 14
- 108020004707 nucleic acids Proteins 0.000 claims 14
- 102000039446 nucleic acids Human genes 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 12
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 9
- 238000000034 method Methods 0.000 claims 5
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 102000003797 Neuropeptides Human genes 0.000 claims 3
- 108090000189 Neuropeptides Proteins 0.000 claims 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 3
- 208000014644 Brain disease Diseases 0.000 claims 2
- 208000016192 Demyelinating disease Diseases 0.000 claims 2
- 208000012239 Developmental disease Diseases 0.000 claims 2
- 208000032274 Encephalopathy Diseases 0.000 claims 2
- 208000031886 HIV Infections Diseases 0.000 claims 2
- 208000037357 HIV infectious disease Diseases 0.000 claims 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 210000000653 nervous system Anatomy 0.000 claims 2
- 230000004770 neurodegeneration Effects 0.000 claims 2
- 208000015122 neurodegenerative disease Diseases 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 102000019034 Chemokines Human genes 0.000 claims 1
- 108010012236 Chemokines Proteins 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 241000584607 Macrospora Species 0.000 claims 1
- 241000320412 Ogataea angusta Species 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 230000027455 binding Effects 0.000 claims 1
- 238000009739 binding Methods 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000003210 demyelinating effect Effects 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 230000003394 haemopoietic effect Effects 0.000 claims 1
- 208000018706 hematopoietic system disease Diseases 0.000 claims 1
- 208000026278 immune system disease Diseases 0.000 claims 1
- 230000010354 integration Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 230000010076 replication Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10027383A DE10027383A1 (de) | 2000-06-02 | 2000-06-02 | Nukleinsäure-Molekül umfassend eine für ein Chemokin, einen Neuropeptid-Präkursor oder mindestens ein Neuropeptid kodierende Nukleinsäuresequenz |
| PCT/EP2001/006250 WO2001092530A1 (de) | 2000-06-02 | 2001-06-01 | Nukleinsäure-molekül umfassend eine für ein sdf-1 gamma chemokin, einen neuropeptid-präkursor oder mindestens ein neuropeptid kodierende nukleinsäuresequenz |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004521607A JP2004521607A (ja) | 2004-07-22 |
| JP2004521607A5 true JP2004521607A5 (https=) | 2005-02-17 |
Family
ID=7644466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002500722A Pending JP2004521607A (ja) | 2000-06-02 | 2001-06-01 | ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20030215792A1 (https=) |
| EP (1) | EP1287142B1 (https=) |
| JP (1) | JP2004521607A (https=) |
| AT (1) | ATE309361T1 (https=) |
| AU (1) | AU6233501A (https=) |
| DE (2) | DE10027383A1 (https=) |
| DK (1) | DK1287142T3 (https=) |
| ES (1) | ES2251483T3 (https=) |
| WO (1) | WO2001092530A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7358044B2 (en) * | 2003-04-16 | 2008-04-15 | Argyll Biotechnologies, Llc. | Prophylactic and therapeutic benefits of a new class of immune stimulating peptides |
| US7776564B2 (en) | 2004-04-30 | 2010-08-17 | Five Prime Therapeutics, Inc. | Stromal cell-derived factor-1 polypeptides, polynucleotides, modulators thereof and methods of use |
| BRPI0617823A2 (pt) * | 2005-10-31 | 2011-08-09 | Laboratoires Serono Sa | uso de sdf-1 para o tratamento e/ou prevenção de doenças neurológicas e composição farmacêutica |
| JP2009532057A (ja) * | 2006-04-07 | 2009-09-10 | ニューロ セラピューティクス エービー | 神経細胞の生存および発生 |
| EP2049146A2 (en) * | 2006-07-07 | 2009-04-22 | Hans-Werner Müller | Use of proteins of the sdf-1-family for for improvement of axonal plasticity or for axonal regeneration following lesions |
| US7696309B2 (en) * | 2006-10-23 | 2010-04-13 | The Brigham And Women's Hospital, Inc. | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| US20110034383A1 (en) * | 2007-10-15 | 2011-02-10 | Institut Pasteur | Cxcl12 gamma a chemokine and uses thereof |
| US9308277B2 (en) | 2010-02-25 | 2016-04-12 | Mesoblast International Sàrl | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| WO2012170495A1 (en) | 2011-06-07 | 2012-12-13 | Provasculon, Inc. | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
| US5885794A (en) * | 1991-05-10 | 1999-03-23 | The Salk Institute For Biological Studies | Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily |
| JP3367581B2 (ja) * | 1993-10-14 | 2003-01-14 | 小野薬品工業株式会社 | 新規なポリペプチド、その製造方法、そのポリペプチドをコードするｄｎａ、そのｄｎａからなるベクター、そのベクターで形質転換された宿主細胞 |
| US6114502A (en) * | 1996-04-10 | 2000-09-05 | Axys Pharmaceuticals, Inc. | Gene family associated with neurosensory defects |
| AU2450797A (en) * | 1996-04-10 | 1997-10-29 | Axys Pharmaceuticals, Inc. | Gene family associated with neurosensory defects |
| US6100387A (en) * | 1997-02-28 | 2000-08-08 | Genetics Institute, Inc. | Chimeric polypeptides containing chemokine domains |
| MXPA00003885A (es) * | 1997-10-22 | 2004-04-23 | Inst Genetics Llc | Quimiocinas con modificiaciones de la terminacion amino. |
| US6747137B1 (en) * | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| AU3773099A (en) * | 1998-04-29 | 1999-11-16 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Identification of polymorphisms in the pctg4 region of xq13 |
| AU5134799A (en) * | 1998-07-30 | 2000-02-21 | Human Genome Sciences, Inc. | 98 human secreted proteins |
| CA2391814A1 (en) * | 1999-12-16 | 2001-06-21 | Ribotargets Limited | Assays |
-
2000
- 2000-06-02 DE DE10027383A patent/DE10027383A1/de not_active Ceased
-
2001
- 2001-06-01 JP JP2002500722A patent/JP2004521607A/ja active Pending
- 2001-06-01 ES ES01936423T patent/ES2251483T3/es not_active Expired - Lifetime
- 2001-06-01 AT AT01936423T patent/ATE309361T1/de not_active IP Right Cessation
- 2001-06-01 EP EP01936423A patent/EP1287142B1/de not_active Expired - Lifetime
- 2001-06-01 WO PCT/EP2001/006250 patent/WO2001092530A1/de not_active Ceased
- 2001-06-01 DK DK01936423T patent/DK1287142T3/da active
- 2001-06-01 AU AU62335/01A patent/AU6233501A/en not_active Abandoned
- 2001-06-01 DE DE50108009T patent/DE50108009D1/de not_active Expired - Lifetime
-
2002
- 2002-12-02 US US10/308,322 patent/US20030215792A1/en not_active Abandoned
-
2008
- 2008-01-22 US US12/010,221 patent/US20080319165A1/en not_active Abandoned
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