WO2001034809A3 - Staphylococcus epidermidis nucleic acids and proteins - Google Patents

Staphylococcus epidermidis nucleic acids and proteins Download PDF

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Publication number
WO2001034809A3
WO2001034809A3 PCT/US2000/030782 US0030782W WO0134809A3 WO 2001034809 A3 WO2001034809 A3 WO 2001034809A3 US 0030782 W US0030782 W US 0030782W WO 0134809 A3 WO0134809 A3 WO 0134809A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
disclosed
epidermidis
proteins
nucleic acids
Prior art date
Application number
PCT/US2000/030782
Other languages
French (fr)
Other versions
WO2001034809A2 (en
Inventor
William John Kimmerly
Original Assignee
Glaxo Group Ltd
William John Kimmerly
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, William John Kimmerly filed Critical Glaxo Group Ltd
Priority to AU14783/01A priority Critical patent/AU1478301A/en
Publication of WO2001034809A2 publication Critical patent/WO2001034809A2/en
Publication of WO2001034809A3 publication Critical patent/WO2001034809A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

S epidermidis polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides and DNA (RNA) for the treatment of infection, particularly infections arising from S epidermidis. Antagonists against the function of such polypeptides and their use as therapeutics to treat infection are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of S epidermidis nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides and polypeptides related to S epidermidis.
PCT/US2000/030782 1999-11-09 2000-11-09 Staphylococcus epidermidis nucleic acids and proteins WO2001034809A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU14783/01A AU1478301A (en) 1999-11-09 2000-11-09 Staphylococcus epidermidis nucleic acids and proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16425899P 1999-11-09 1999-11-09
US60/164,258 1999-11-09

Publications (2)

Publication Number Publication Date
WO2001034809A2 WO2001034809A2 (en) 2001-05-17
WO2001034809A3 true WO2001034809A3 (en) 2001-11-22

Family

ID=22593682

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/030782 WO2001034809A2 (en) 1999-11-09 2000-11-09 Staphylococcus epidermidis nucleic acids and proteins

Country Status (2)

Country Link
AU (1) AU1478301A (en)
WO (1) WO2001034809A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides

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US6380370B1 (en) 1997-08-14 2002-04-30 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
PL201887B1 (en) 1998-12-22 2009-05-29 Microscience Ltd Genes and proteins, and their use
US6720139B1 (en) 1999-01-27 2004-04-13 Elitra Pharmaceuticals, Inc. Genes identified as required for proliferation in Escherichia coli
US6764823B2 (en) 2000-04-06 2004-07-20 Pharmacia & Upjohn Company Antimicrobial methods and materials
FR2829148B1 (en) * 2001-09-06 2004-10-15 Univ Aix Marseille Ii MOLECULAR IDENTIFICATION OF STAPHYLOCOCCUS BACTERIA
WO2003029484A2 (en) * 2001-09-28 2003-04-10 Pharmacia & Upjohn Company Antimicrobial methods and materials
US6929935B2 (en) 2001-12-19 2005-08-16 Bristol-Myers Squibb Company Gluconobacter oxydans 2-ketoreductase enzyme and applications thereof
DE10232776A1 (en) * 2002-07-18 2004-04-08 Henkel Kgaa New oligonucleotides for specific detection of microorganisms, useful e.g. for detecting or quantifying microbes on the skin, in foods, clinical samples or water, by in situ hybridization
DE602004024179D1 (en) * 2003-03-31 2009-12-31 Intercell Ag STAPHYLOCOCCUS EPIDERMIDIS ANTIGENE
JP2004313181A (en) * 2003-04-02 2004-11-11 Canon Inc Probe for detecting infection-inducing microbe, probe set, carrier and method for testing gene
FR2857375B1 (en) * 2003-07-10 2007-11-09 Biomerieux Sa PROCESS FOR THE DETECTION AND / OR IDENTIFICATION OF STAPHYLOCOCCUS GENE BACTERIA
FR2871237B1 (en) * 2004-06-08 2011-03-11 Abag NOVEL POLYPEPTIDES FOR IN VITRO ASSESSMENT AND PREVENTION OF STAPHYLOCOCCAL INFECTIONS ON JOINT PROSTHESES AND OTHER FOREIGN ABRIDGED MATERIALS
FR2871159A1 (en) * 2004-06-08 2005-12-09 Abag Sa New isolated polynucleotide encoding antigens of Staphylococcus, also encoded proteins and derived antibodies, useful for diagnosis of Staphylococcus epidermidis infections and in vaccines
JP2008513409A (en) 2004-09-22 2008-05-01 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Immunogenic composition
EP1802335A2 (en) 2004-10-21 2007-07-04 Wyeth a Corporation of the State of Delaware Immunogenic compositions of staphylococcus epidermidis polypeptide and polynucleotide antigens
CN101432017B (en) 2005-01-21 2011-12-21 默沙东公司 Polypeptides for inducing a protective immune response against staphylococcus aureus
EP3141261A1 (en) 2006-03-30 2017-03-15 GlaxoSmithKline Biologicals S.A. Immunogenic composition
EP1980269A1 (en) * 2007-04-13 2008-10-15 Katholieke Universiteit Leuven Prevention of staphylococcus biofilm formation
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
EP2185190B1 (en) 2007-08-31 2015-06-24 University Of Chicago Methods and compositions related to immunizing against staphylococcal lung diseases and conditions
US8758765B2 (en) 2008-07-29 2014-06-24 The University Of Chicago Compositions and methods related to Staphylococcal bacterium proteins
PL2414387T3 (en) 2009-04-03 2016-06-30 Univ Chicago Compositions and methods related to protein a (spa) variants
WO2011127032A1 (en) 2010-04-05 2011-10-13 University Of Chicago Compositions and methods related to protein a (spa) antibodies as an enhancer of immune response
PE20110023A1 (en) 2009-06-22 2011-01-31 Wyeth Llc IMMUNOGENIC COMPOSITIONS OF STAPHYLOCOCCUS AUREUS ANTIGENS
MY165191A (en) * 2009-12-30 2018-02-28 Univ Putra Malaysia Upm Novel organic solvent lipase gene
KR20130093084A (en) 2010-07-02 2013-08-21 더 유니버시티 오브 시카고 Compositions and methods related to protein a(spa) variants
US9095540B2 (en) 2010-09-09 2015-08-04 The University Of Chicago Methods and compositions involving protective staphylococcal antigens
EP3805395A1 (en) 2012-04-26 2021-04-14 University Of Chicago Staphylococcal coagulase antigens and methods of their use
EP4323013A2 (en) * 2021-04-13 2024-02-21 Capsida, Inc. Selected aav compositions having preferred brain enrichment
CN117511763A (en) * 2022-08-05 2024-02-06 天康制药股份有限公司 High-density fermentation medium for staphylococcus epidermidis as well as fermentation method and application of high-density fermentation medium

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US5587307A (en) * 1993-04-30 1996-12-24 Eli Lilly And Company FemA gene of staphylococcus epidermidis, femA protein, and vectors and microorganisms comprising the femA gene
US5770375A (en) * 1992-07-07 1998-06-23 Tsuneya Ohno Probe for diagnosing staphylococcus epidermidis
US5961975A (en) * 1991-11-22 1999-10-05 Nabi Type I surface antigen associated with staphylococcus epidermidis

Patent Citations (3)

* Cited by examiner, † Cited by third party
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US5961975A (en) * 1991-11-22 1999-10-05 Nabi Type I surface antigen associated with staphylococcus epidermidis
US5770375A (en) * 1992-07-07 1998-06-23 Tsuneya Ohno Probe for diagnosing staphylococcus epidermidis
US5587307A (en) * 1993-04-30 1996-12-24 Eli Lilly And Company FemA gene of staphylococcus epidermidis, femA protein, and vectors and microorganisms comprising the femA gene

Non-Patent Citations (2)

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Title
DATABASE EMBL EBI; 5 February 1991 (1991-02-05), BHAT ET AL.: "T.brucei kinetoplast ATPase 6 edited mRNA, complete cds.", XP002163041 *
VAN DE KAMP ET AL.: "Elucidation of the primary structure of the lantibiotic epilancin K7 from Staphylococcus epidermidis K7. Cloning and characterisation of the epilancin-K7-encoding gene and NMR analysis of mature epilancin K7", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 230, no. 2, 1 June 1995 (1995-06-01), pages 587 - 600, XP000990390 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides

Also Published As

Publication number Publication date
WO2001034809A2 (en) 2001-05-17
AU1478301A (en) 2001-06-06

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