JP2004531242A5 - - Google Patents
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- Publication number
- JP2004531242A5 JP2004531242A5 JP2002571881A JP2002571881A JP2004531242A5 JP 2004531242 A5 JP2004531242 A5 JP 2004531242A5 JP 2002571881 A JP2002571881 A JP 2002571881A JP 2002571881 A JP2002571881 A JP 2002571881A JP 2004531242 A5 JP2004531242 A5 JP 2004531242A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- host cell
- seq
- amino acids
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 208000004296 neuralgia Diseases 0.000 claims 2
- 208000021722 neuropathic pain Diseases 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/804,615 US20020055467A1 (en) | 1998-07-06 | 2001-03-12 | Novel neurotrophic factors |
| PCT/EP2002/002691 WO2002072826A2 (en) | 2001-03-12 | 2002-03-12 | Neurotrophic factors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005027109A Division JP2005198656A (ja) | 2001-03-12 | 2005-02-02 | 神経栄養因子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004531242A JP2004531242A (ja) | 2004-10-14 |
| JP2004531242A5 true JP2004531242A5 (https=) | 2005-06-23 |
| JP3738008B2 JP3738008B2 (ja) | 2006-01-25 |
Family
ID=25189406
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002571881A Expired - Fee Related JP3738008B2 (ja) | 2001-03-12 | 2002-03-12 | 神経栄養因子 |
| JP2005027109A Withdrawn JP2005198656A (ja) | 2001-03-12 | 2005-02-02 | 神経栄養因子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005027109A Withdrawn JP2005198656A (ja) | 2001-03-12 | 2005-02-02 | 神経栄養因子 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20020055467A1 (https=) |
| EP (2) | EP1373503B1 (https=) |
| JP (2) | JP3738008B2 (https=) |
| CN (1) | CN1268744C (https=) |
| AT (2) | ATE509103T1 (https=) |
| AU (1) | AU2002240943B2 (https=) |
| CA (1) | CA2440767C (https=) |
| CY (1) | CY1111750T1 (https=) |
| DE (1) | DE60223511T2 (https=) |
| DK (2) | DK1930439T3 (https=) |
| ES (2) | ES2366610T3 (https=) |
| NZ (1) | NZ528790A (https=) |
| PT (2) | PT1373503E (https=) |
| SI (2) | SI1930439T1 (https=) |
| WO (1) | WO2002072826A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| HK1045528B (zh) * | 1998-07-14 | 2006-10-27 | 詹森药业有限公司 | 神经营养生长因子 |
| NZ526610A (en) * | 2000-12-22 | 2009-08-28 | Genentech Inc | New use of artemin, a member of the GDNF ligand family |
| US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| CN1525866B (zh) * | 2001-03-28 | 2013-05-29 | 比奥根艾迪克Ma公司 | 神经胚活素多肽的治疗作用 |
| EP1463530A4 (en) * | 2001-12-19 | 2006-09-06 | Lijun Wang | ADENO-ASSOCIATED VIRUS-RELATED DELIVERY OF GDNF TO SKELETAL MUSCLES |
| JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Ｊｘ日鉱日石エネルギー株式会社 | 潤滑油組成物 |
| EA008743B1 (ru) * | 2003-01-31 | 2007-08-31 | Байоджен Айдек Ма Инк. | Полимерные конъюгаты мутантного неубластина |
| WO2004094592A2 (en) * | 2003-04-18 | 2004-11-04 | Biogen Idec Ma Inc. | Polymer-conjugated glycosylated neublastin |
| NZ544263A (en) | 2003-06-10 | 2009-04-30 | Nsgene As | Improved secretion of neublastin |
| US7598059B2 (en) * | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| BRPI0415563A (pt) | 2003-10-20 | 2007-01-02 | Nsgene As | método para o tratamento do mal de parkinson, uso de um vetor viral, vetor de expressão viral, composição farmacêutica, célula hospedeira isolada, linhagem de células de empacotamento, mamìfero não humano quimérico, dispositivo de cultura celular implantável, cápsula biocompatìvel, método para tratamento de uma doença do sistema nervoso, célula de mamìfero, e, método para produzir neurturin ou um seu equivalente funcional |
| DK1786454T3 (da) * | 2004-08-19 | 2010-09-06 | Biogen Idec Inc | Neublastinvarianter |
| CA2577690C (en) * | 2004-08-19 | 2013-08-06 | Biogen Idec Ma Inc. | Refolding transforming growth factor beta family proteins |
| US20080260702A1 (en) * | 2005-10-11 | 2008-10-23 | Jesper Roland Jorgensen | Treatment of Retinopathies Using Gfra3 Agonists |
| TWI501774B (zh) * | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| ES2450065T3 (es) * | 2006-03-01 | 2014-03-21 | Biogen Idec Ma Inc. | Composiciones y métodos para la administración de proteínas de la familia de ligandos del GDNF |
| EP2142205B1 (en) | 2007-05-01 | 2014-04-02 | Biogen Idec MA Inc. | Neublastin peptides for use in increasing vascularisation in tissue with impaired blood flow |
| WO2009020964A2 (en) * | 2007-08-08 | 2009-02-12 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
| US20100247437A1 (en) * | 2007-10-01 | 2010-09-30 | Vgx Pharmaceuticals, Llc | Materials and methods for the delivery of biomolecules to cells of an organ |
| WO2012041328A1 (en) * | 2010-10-01 | 2012-04-05 | Nsgene A/S | Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain |
| KR20200144576A (ko) * | 2018-05-17 | 2020-12-29 | 주식회사 헬릭스미스 | 화학요법-유발 말초신경병증과 관련된 신경병증성 통증의 치료 |
| WO2022244757A1 (ja) | 2021-05-18 | 2022-11-24 | 株式会社Ｌｔｔバイオファーマ | 抗癌剤の投与に伴う障害を治療又は予防するための医薬組成物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
| CN1163509C (zh) | 1996-05-08 | 2004-08-25 | 拜奥根有限公司 | 刺激神经和肾生长的RET配体(RetL) |
| WO2000073348A2 (en) * | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| US6284540B1 (en) * | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
| WO2000034475A2 (en) * | 1998-12-09 | 2000-06-15 | Amgen Inc. | Grnf4, a gdnf-related neurotrophic factor |
-
2001
- 2001-03-12 US US09/804,615 patent/US20020055467A1/en not_active Abandoned
-
2002
- 2002-03-12 ES ES07120461T patent/ES2366610T3/es not_active Expired - Lifetime
- 2002-03-12 JP JP2002571881A patent/JP3738008B2/ja not_active Expired - Fee Related
- 2002-03-12 NZ NZ528790A patent/NZ528790A/en not_active IP Right Cessation
- 2002-03-12 WO PCT/EP2002/002691 patent/WO2002072826A2/en not_active Ceased
- 2002-03-12 DE DE60223511T patent/DE60223511T2/de not_active Expired - Lifetime
- 2002-03-12 AT AT07120461T patent/ATE509103T1/de active
- 2002-03-12 EP EP02706759A patent/EP1373503B1/en not_active Expired - Lifetime
- 2002-03-12 AT AT02706759T patent/ATE378353T1/de active
- 2002-03-12 DK DK07120461.4T patent/DK1930439T3/da active
- 2002-03-12 PT PT02706759T patent/PT1373503E/pt unknown
- 2002-03-12 SI SI200230954T patent/SI1930439T1/sl unknown
- 2002-03-12 CN CNB028097858A patent/CN1268744C/zh not_active Expired - Fee Related
- 2002-03-12 PT PT07120461T patent/PT1930439E/pt unknown
- 2002-03-12 EP EP07120461A patent/EP1930439B1/en not_active Expired - Lifetime
- 2002-03-12 SI SI200230656T patent/SI1373503T1/sl unknown
- 2002-03-12 ES ES02706759T patent/ES2296899T3/es not_active Expired - Lifetime
- 2002-03-12 DK DK02706759T patent/DK1373503T3/da active
- 2002-03-12 AU AU2002240943A patent/AU2002240943B2/en not_active Ceased
- 2002-03-12 CA CA2440767A patent/CA2440767C/en not_active Expired - Fee Related
-
2005
- 2005-02-02 JP JP2005027109A patent/JP2005198656A/ja not_active Withdrawn
-
2011
- 2011-08-10 CY CY20111100765T patent/CY1111750T1/el unknown
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