JP2004521607A - ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子 - Google Patents

ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子 Download PDF

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JP2004521607A
JP2004521607A JP2002500722A JP2002500722A JP2004521607A JP 2004521607 A JP2004521607 A JP 2004521607A JP 2002500722 A JP2002500722 A JP 2002500722A JP 2002500722 A JP2002500722 A JP 2002500722A JP 2004521607 A JP2004521607 A JP 2004521607A
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nucleic acid
sdf
seq
acid sequence
fragment
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JP2004521607A5 (https=
Inventor
ハンス、ベルナー、ミューラー
フランク、ボッセ
マルク、グライヒマン
クレメンス、ギレン
ヨハネス、アウエル
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NEURAXO BIOTEC GmbH
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NEURAXO BIOTEC GmbH
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/522Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002500722A 2000-06-02 2001-06-01 ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子 Pending JP2004521607A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10027383A DE10027383A1 (de) 2000-06-02 2000-06-02 Nukleinsäure-Molekül umfassend eine für ein Chemokin, einen Neuropeptid-Präkursor oder mindestens ein Neuropeptid kodierende Nukleinsäuresequenz
PCT/EP2001/006250 WO2001092530A1 (de) 2000-06-02 2001-06-01 Nukleinsäure-molekül umfassend eine für ein sdf-1 gamma chemokin, einen neuropeptid-präkursor oder mindestens ein neuropeptid kodierende nukleinsäuresequenz

Publications (2)

Publication Number Publication Date
JP2004521607A true JP2004521607A (ja) 2004-07-22
JP2004521607A5 JP2004521607A5 (https=) 2005-02-17

Family

ID=7644466

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002500722A Pending JP2004521607A (ja) 2000-06-02 2001-06-01 ケモカイン、神経ペプチド前駆体または少なくとも一つの神経ペプチドをコードする核酸配列を含んでなる核酸分子

Country Status (9)

Country Link
US (2) US20030215792A1 (https=)
EP (1) EP1287142B1 (https=)
JP (1) JP2004521607A (https=)
AT (1) ATE309361T1 (https=)
AU (1) AU6233501A (https=)
DE (2) DE10027383A1 (https=)
DK (1) DK1287142T3 (https=)
ES (1) ES2251483T3 (https=)
WO (1) WO2001092530A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7358044B2 (en) * 2003-04-16 2008-04-15 Argyll Biotechnologies, Llc. Prophylactic and therapeutic benefits of a new class of immune stimulating peptides
US7776564B2 (en) 2004-04-30 2010-08-17 Five Prime Therapeutics, Inc. Stromal cell-derived factor-1 polypeptides, polynucleotides, modulators thereof and methods of use
BRPI0617823A2 (pt) * 2005-10-31 2011-08-09 Laboratoires Serono Sa uso de sdf-1 para o tratamento e/ou prevenção de doenças neurológicas e composição farmacêutica
JP2009532057A (ja) * 2006-04-07 2009-09-10 ニューロ セラピューティクス エービー 神経細胞の生存および発生
EP2049146A2 (en) * 2006-07-07 2009-04-22 Hans-Werner Müller Use of proteins of the sdf-1-family for for improvement of axonal plasticity or for axonal regeneration following lesions
US7696309B2 (en) * 2006-10-23 2010-04-13 The Brigham And Women's Hospital, Inc. Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
US20110034383A1 (en) * 2007-10-15 2011-02-10 Institut Pasteur Cxcl12 gamma a chemokine and uses thereof
US9308277B2 (en) 2010-02-25 2016-04-12 Mesoblast International Sàrl Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
WO2012170495A1 (en) 2011-06-07 2012-12-13 Provasculon, Inc. Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5885794A (en) * 1991-05-10 1999-03-23 The Salk Institute For Biological Studies Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
JP3367581B2 (ja) * 1993-10-14 2003-01-14 小野薬品工業株式会社 新規なポリペプチド、その製造方法、そのポリペプチドをコードするdna、そのdnaからなるベクター、そのベクターで形質転換された宿主細胞
US6114502A (en) * 1996-04-10 2000-09-05 Axys Pharmaceuticals, Inc. Gene family associated with neurosensory defects
AU2450797A (en) * 1996-04-10 1997-10-29 Axys Pharmaceuticals, Inc. Gene family associated with neurosensory defects
US6100387A (en) * 1997-02-28 2000-08-08 Genetics Institute, Inc. Chimeric polypeptides containing chemokine domains
MXPA00003885A (es) * 1997-10-22 2004-04-23 Inst Genetics Llc Quimiocinas con modificiaciones de la terminacion amino.
US6747137B1 (en) * 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
AU3773099A (en) * 1998-04-29 1999-11-16 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Identification of polymorphisms in the pctg4 region of xq13
AU5134799A (en) * 1998-07-30 2000-02-21 Human Genome Sciences, Inc. 98 human secreted proteins
CA2391814A1 (en) * 1999-12-16 2001-06-21 Ribotargets Limited Assays

Also Published As

Publication number Publication date
DE50108009D1 (de) 2005-12-15
ATE309361T1 (de) 2005-11-15
US20080319165A1 (en) 2008-12-25
WO2001092530A1 (de) 2001-12-06
AU6233501A (en) 2001-12-11
EP1287142B1 (de) 2005-11-09
ES2251483T3 (es) 2006-05-01
DK1287142T3 (da) 2006-03-13
US20030215792A1 (en) 2003-11-20
DE10027383A1 (de) 2001-12-20
EP1287142A1 (de) 2003-03-05

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