JP2004520438A5 - - Google Patents

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Publication number
JP2004520438A5
JP2004520438A5 JP2002576206A JP2002576206A JP2004520438A5 JP 2004520438 A5 JP2004520438 A5 JP 2004520438A5 JP 2002576206 A JP2002576206 A JP 2002576206A JP 2002576206 A JP2002576206 A JP 2002576206A JP 2004520438 A5 JP2004520438 A5 JP 2004520438A5
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JP
Japan
Prior art keywords
alkyl
aryl
amino
alkoxy
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002576206A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004520438A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/006475 external-priority patent/WO2002076945A1/en
Publication of JP2004520438A publication Critical patent/JP2004520438A/ja
Publication of JP2004520438A5 publication Critical patent/JP2004520438A5/ja
Pending legal-status Critical Current

Links

JP2002576206A 2001-03-09 2002-03-05 セリンプロテアーゼインヒビターとしてのアミノピロリジンスルホンアミド Pending JP2004520438A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27484501P 2001-03-09 2001-03-09
PCT/US2002/006475 WO2002076945A1 (en) 2001-03-09 2002-03-05 Aminopyrrolidine sulfonamides as serine protease inhibitors

Publications (2)

Publication Number Publication Date
JP2004520438A JP2004520438A (ja) 2004-07-08
JP2004520438A5 true JP2004520438A5 (enExample) 2005-12-22

Family

ID=23049830

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002576206A Pending JP2004520438A (ja) 2001-03-09 2002-03-05 セリンプロテアーゼインヒビターとしてのアミノピロリジンスルホンアミド

Country Status (5)

Country Link
US (2) US6538017B2 (enExample)
EP (1) EP1385822A1 (enExample)
JP (1) JP2004520438A (enExample)
CA (1) CA2440389A1 (enExample)
WO (1) WO2002076945A1 (enExample)

Families Citing this family (15)

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US20020128476A1 (en) * 1996-08-08 2002-09-12 Smithkline Beecham Corporation Inhibitors of cysteine protease
CA2479618A1 (en) 2002-03-26 2003-10-09 William K. Hagmann Spirocyclic amides as cannabinoid receptor modulators
JP2005531520A (ja) 2002-03-28 2005-10-20 メルク　エンド　カムパニー　インコーポレーテッド 置換２，３−ジフェニルピリジン類
EP1499306A4 (en) 2002-04-12 2007-03-28 Merck & Co Inc BICYCLIC AMIDE
BRPI0316732B8 (pt) 2002-11-27 2021-05-25 Incyte Corp composto derivado de 3-aminopirrolidina e sua composição farmacêutica
US20050119266A1 (en) * 2003-10-01 2005-06-02 Yan Shi Pyrrolidine and piperidine derivatives as factor Xa inhibitors
US20060078580A1 (en) * 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US7740875B2 (en) * 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US9580810B2 (en) * 2007-02-27 2017-02-28 Mitsubishi Materials Corporation Dispersion of metal nanoparticles, method for producing the same, and method for synthesizing metal nanoparticles
US10077268B2 (en) 2014-03-13 2018-09-18 Salk Institute For Biological Studies FXR agonists and methods for making and using
KR20160133529A (ko) * 2014-03-13 2016-11-22 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 펙사라민 유도체 및 이의 제조와 사용 방법
US10301268B2 (en) 2014-03-13 2019-05-28 The Salk Institute For Biological Studies Analogs of fexaramine and methods of making and using
WO2017078927A1 (en) * 2015-11-06 2017-05-11 Salk Institute For Biological Studies Analogs of fexaramine and methods of making and using
CA3004095A1 (en) 2015-11-09 2017-05-18 Cortexyme, Inc. Inhibitors of arginine gingipain
WO2025039979A1 (zh) * 2023-08-18 2025-02-27 江苏亚虹医药科技股份有限公司 蛋白质精氨酸酶甲基转移酶-5抑制剂及其医药用途

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000623B1 (en) 1977-07-08 1981-12-30 LUCAS INDUSTRIES public limited company Printed circuit edge connector
GB8512163D0 (en) 1985-05-14 1985-06-19 Fujisawa Pharmaceutical Co Oxothiazolidine compound
CA1322199C (en) 1987-07-15 1993-09-14 Masami Eigyo N-¬(2-oxopyrrolidin-1-yl) acetyl)| piperazine derivatives and drug for senile dementia
EP0635008B1 (de) 1993-02-10 2002-09-04 Pentapharm A.G. Piperazide von substituierten phenylalanin-derivativen als thrombin inhibitoren
CA2122397A1 (en) * 1993-05-03 1994-11-04 Spencer D. Kimball Guanidinyl- or amidinyl-substituted heterocyclic thrombin inhibitors
US5681844A (en) * 1994-04-18 1997-10-28 Corvas International, Inc. Methionine sulfone and s-substituted cysteine sulfone derivatives as enzyme inhibitors
WO1996005189A1 (de) 1994-08-09 1996-02-22 Pentapharm Ag Neue inhibitoren vom benzamidintyp
IL115420A0 (en) 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
PT798295E (pt) 1994-12-02 2003-07-31 Yamanouchi Pharma Co Ltd Novo derivado de amidinonaftilo ou sal deste
JP3125624B2 (ja) 1995-04-21 2001-01-22 株式会社村田製作所 圧電磁器
KR0173034B1 (ko) 1995-04-28 1999-03-30 성재갑 선택적 트롬빈 억제제
TW438591B (en) 1995-06-07 2001-06-07 Arris Pharm Corp Reversible cysteine protease inhibitors
US5612353A (en) 1995-06-07 1997-03-18 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds
EP0838460A4 (en) 1995-07-13 1998-11-04 Senju Pharma Co PIPERAZINE DERIVATIVES AND USES THEREOF
WO1997019919A1 (en) 1995-11-30 1997-06-05 C & C Research Laboratories Sulfamide derivatives
PL329413A1 (en) 1996-04-24 1999-03-29 Novo Nordisk As Chemical compounds exhibiting properties capable to cause growth hormone release
DZ2285A1 (fr) 1996-08-08 2002-12-25 Smithkline Beecham Corp Inhibiteurs de protéase de la cystéine.
WO1998054164A1 (en) * 1997-05-30 1998-12-03 Takeda Chemical Industries, Ltd. Sulfonamide derivatives, their production and use
EP0993448A1 (en) * 1997-06-19 2000-04-19 The Du Pont Merck Pharmaceutical Company (AMIDINO)6-MEMBERED AROMATICS AS FACTOR Xa INHIBITORS
DE69833036T2 (de) * 1997-09-30 2006-06-22 Daiichi Pharmaceutical Co., Ltd. Sulfonylderivate

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