JP2004516013A5 - - Google Patents
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- Publication number
- JP2004516013A5 JP2004516013A5 JP2002514188A JP2002514188A JP2004516013A5 JP 2004516013 A5 JP2004516013 A5 JP 2004516013A5 JP 2002514188 A JP2002514188 A JP 2002514188A JP 2002514188 A JP2002514188 A JP 2002514188A JP 2004516013 A5 JP2004516013 A5 JP 2004516013A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- nucleic acid
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Applications Claiming Priority (36)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21955600P | 2000-07-20 | 2000-07-20 | |
US22062400P | 2000-07-25 | 2000-07-25 | |
US22066400P | 2000-07-25 | 2000-07-25 | |
PCT/US2000/020710 WO2001009327A2 (en) | 1999-07-28 | 2000-07-28 | Method of preventing the injury or death of retinal cells and treating ocular diseases |
US22269500P | 2000-08-02 | 2000-08-02 | |
US09/643,657 US6642024B1 (en) | 1998-01-29 | 2000-08-17 | Guanylate-binding protein |
PCT/US2000/023522 WO2001016319A2 (en) | 1999-08-31 | 2000-08-23 | Compositions and methods for the treatment of immune related diseases |
PCT/US2000/023328 WO2001016318A2 (en) | 1999-09-01 | 2000-08-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US23097800P | 2000-09-07 | 2000-09-07 | |
US66461000A | 2000-09-18 | 2000-09-18 | |
US66535000A | 2000-09-18 | 2000-09-18 | |
US24292200P | 2000-10-24 | 2000-10-24 | |
US70923800A | 2000-11-08 | 2000-11-08 | |
PCT/US2000/030952 WO2001049715A2 (en) | 2000-01-06 | 2000-11-08 | Methods and compositions for inhibiting neoplastic cell growth |
PCT/US2000/030873 WO2001040465A2 (en) | 1999-11-30 | 2000-11-10 | Compositions and methods for the treatment of immune related diseases |
PCT/US2000/032678 WO2001040466A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
PCT/US2000/034956 WO2001046420A2 (en) | 1999-12-23 | 2000-12-20 | Il-17 and il-17r homologous polypeptides and therapeutic uses thereof |
US09/747,259 US6569645B2 (en) | 1999-05-14 | 2000-12-20 | IL-17 homologous polypeptides and therapeutic uses thereof |
US09/767,609 US20020042367A1 (en) | 1997-11-25 | 2001-01-22 | Fibroblast growth factor-19 (FGF-19) nucleic acids and polypeptides and methods of use for the treatment of obesity and related disorders |
US79649801A | 2001-02-28 | 2001-02-28 | |
PCT/US2001/006520 WO2001068848A2 (en) | 2000-03-01 | 2001-02-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
PCT/US2001/006666 WO2001066740A2 (en) | 2000-03-03 | 2001-03-01 | Compositions and methods for the treatment of immune related diseases |
US80270601A | 2001-03-09 | 2001-03-09 | |
US80868901A | 2001-03-14 | 2001-03-14 | |
US09/816,744 US6579520B2 (en) | 1998-05-15 | 2001-03-22 | IL-17 related mammalian cytokine polypeptides (IL-17E) |
US09/828,366 US20020010137A1 (en) | 1997-09-18 | 2001-04-05 | Methods and compositions for inhibiting neoplastic cell growth |
US09/854,208 US7217412B2 (en) | 1998-05-15 | 2001-05-10 | IL-17C related mammalian cytokine polypeptides |
US09/854,280 US7115398B2 (en) | 1998-05-15 | 2001-05-10 | IL-17 homologous polypeptides and therapeutic uses thereof |
US09/866,034 US20030170864A1 (en) | 2000-05-30 | 2001-05-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/866,028 US6642360B2 (en) | 1997-12-03 | 2001-05-25 | Secreted polypeptides that stimulate release of proteoglycans from cartilage |
PCT/US2001/017092 WO2001092331A2 (en) | 2000-05-30 | 2001-05-25 | Compositions and methods for the treatment of immune related diseases |
US09/870,574 US6551799B2 (en) | 1999-12-07 | 2001-05-30 | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
PCT/US2001/017443 WO2002016611A2 (en) | 2000-08-24 | 2001-05-30 | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
PCT/US2001/017800 WO2001093983A1 (en) | 2000-06-02 | 2001-06-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
PCT/US2001/019692 WO2002000690A2 (en) | 2000-06-23 | 2001-06-20 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
PCT/US2001/021735 WO2002008284A2 (en) | 2000-07-20 | 2001-07-09 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
Related Child Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008194721A Division JP2009039118A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2008194678A Division JP2009039117A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2008194764A Division JP2009039119A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2011173336A Division JP6033531B2 (ja) | 2000-07-20 | 2011-08-08 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2004516013A JP2004516013A (ja) | 2004-06-03 |
JP2004516013A5 true JP2004516013A5 (enrdf_load_stackoverflow) | 2010-07-15 |
Family
ID=56290165
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002514188A Withdrawn JP2004516013A (ja) | 2000-07-20 | 2001-07-09 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2008194764A Withdrawn JP2009039119A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2008194721A Withdrawn JP2009039118A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2008194678A Withdrawn JP2009039117A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2011173336A Expired - Fee Related JP6033531B2 (ja) | 2000-07-20 | 2011-08-08 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008194764A Withdrawn JP2009039119A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2008194721A Withdrawn JP2009039118A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2008194678A Withdrawn JP2009039117A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
JP2011173336A Expired - Fee Related JP6033531B2 (ja) | 2000-07-20 | 2011-08-08 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1309685A2 (enrdf_load_stackoverflow) |
JP (5) | JP2004516013A (enrdf_load_stackoverflow) |
AU (1) | AU2001271973A1 (enrdf_load_stackoverflow) |
CA (1) | CA2416538A1 (enrdf_load_stackoverflow) |
WO (1) | WO2002008284A2 (enrdf_load_stackoverflow) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002000690A2 (en) * | 2000-06-23 | 2002-01-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
WO1999012963A2 (en) | 1997-09-12 | 1999-03-18 | Biogen, Inc. | Cysteine rich receptors: trail |
US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
US7192589B2 (en) | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
US8007798B2 (en) | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
US8088386B2 (en) | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
US7771719B1 (en) | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
IL138930A0 (en) | 1998-05-15 | 2001-11-25 | Genentech Inc | Il-17 homologies polypeptides and therapeutic uses thereof |
US20030187196A1 (en) | 1998-12-30 | 2003-10-02 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US20030095967A1 (en) | 1999-01-25 | 2003-05-22 | Mackay Fabienne | BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders |
US7589172B2 (en) | 1999-07-20 | 2009-09-15 | Genentech, Inc. | PRO256 polypeptides |
PT1992695E (pt) | 1999-08-12 | 2011-01-12 | Agensys Inc | Antigénio transmembranar lectina tipo c expresso em cancro da próstata humano e utilizações do mesmo |
EP1637541B1 (en) * | 1999-09-01 | 2010-03-03 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
DK1228208T3 (da) | 1999-10-28 | 2010-11-22 | Agensys Inc | 36P6D5: udskilt tumorantigen |
EP1897946B1 (en) * | 1999-12-23 | 2012-07-11 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
US20040043397A1 (en) | 2000-01-11 | 2004-03-04 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
US7718397B2 (en) | 2000-03-21 | 2010-05-18 | Genentech, Inc. | Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof |
PT1283214E (pt) * | 2000-04-21 | 2007-03-30 | Fuso Pharmaceutical Ind | Novas colectinas |
US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP2792747A1 (en) * | 2000-06-23 | 2014-10-22 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
CA2648046A1 (en) * | 2000-06-23 | 2002-01-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
US7115415B2 (en) | 2000-09-15 | 2006-10-03 | Genentech, Inc. | PRO9821 nucleic acids |
US6630325B1 (en) * | 2000-10-19 | 2003-10-07 | Maine Medical Center Research Institute | Compositions, methods and kits relating to remodel |
US20060141453A9 (en) | 2000-11-03 | 2006-06-29 | Qun-Yong Zhou | Prokineticin polypeptides, related compositions and methods |
WO2002040654A2 (en) | 2000-11-14 | 2002-05-23 | Bristol-Myers Squibb Company | A human serpin secreted from lymphoid cells lsi-01 |
US20030119112A1 (en) | 2001-06-20 | 2003-06-26 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
AU2003215761A1 (en) * | 2002-03-22 | 2003-10-08 | Bioxell S.P.A. | A novel receptor trem (triggering receptor expressed on myeloid cells) and uses thereof |
AU2003220805A1 (en) * | 2002-03-28 | 2003-10-13 | Yamanouchi Pharmaceutical Co., Ltd. | Antiopoietin-related growth factor |
JP2005536190A (ja) * | 2002-04-16 | 2005-12-02 | ジェネンテック・インコーポレーテッド | 腫瘍の診断と治療のための組成物と方法 |
EP2305710A3 (en) | 2002-06-03 | 2013-05-29 | Genentech, Inc. | Synthetic antibody phage libraries |
WO2004022087A1 (ja) * | 2002-09-04 | 2004-03-18 | Takeda Pharmaceutical Company Limited | 疾患関連遺伝子の用途 |
WO2004024076A2 (en) * | 2002-09-11 | 2004-03-25 | Genentech, Inc. | Novel compositions and methods for the treatment of immune related diseases |
JP2006513700A (ja) * | 2002-09-25 | 2006-04-27 | ジェネンテック・インコーポレーテッド | 乾癬の治療のための新規組成物と方法 |
KR101294959B1 (ko) | 2003-03-12 | 2013-08-09 | 제넨테크, 인크. | 조혈을 촉진하기 위한 bv8 및(또는) eg-vegf의 용도 |
DK2784084T4 (da) | 2003-07-08 | 2024-01-08 | Novartis Pharma Ag | Antagonist-antistoffer mod IL-17A/F heterologe polypeptider |
US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
NZ550110A (en) | 2004-04-14 | 2009-09-25 | Genentech Inc | Compositions and methods comprising an EGFL7 antagonist for modulating vascular development |
PT1781682E (pt) | 2004-06-24 | 2013-05-14 | Mayo Foundation | B7-h5, um polipéptido coestimulante |
KR20070036089A (ko) | 2004-07-02 | 2007-04-02 | 제넨테크, 인크. | 비호지킨 림프종의 치료 방법 및 치료 조성물 |
EP1789070B1 (en) | 2004-08-03 | 2012-10-24 | Biogen Idec MA Inc. | Taj in neuronal function |
US7906116B2 (en) | 2005-09-01 | 2011-03-15 | Parkash Gill | Methods for using and identifying modulators of Delta-like 4 |
NZ594285A (en) | 2005-11-04 | 2013-02-22 | Genentech Inc | USE OF COMPLEMENT PATHWAY INHIBITOR ANTIBODY AGAINST C5a TO TREAT OCULAR DISEASES |
MY157948A (en) | 2006-11-02 | 2016-08-30 | Genentech Inc | Humanized anti-factor d antibodies |
AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
BRPI0820387A2 (pt) * | 2007-11-21 | 2015-05-26 | Amgen Inc | Agentes de ligação de wise e epítopos |
CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
KR101508086B1 (ko) | 2008-05-05 | 2015-04-07 | 노비뮨 에스 에이 | 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법 |
RU2015117054A (ru) | 2008-05-06 | 2015-10-20 | Дженентек, Инк. | ВАРИАНТЫ CRIg С СОЗРЕВШЕЙ АФФИНОСТЬЮ |
CN107028969A (zh) | 2009-02-20 | 2017-08-11 | 加尼梅德药物公司 | 用于癌症诊断和治疗的方法和组合物 |
KR101811886B1 (ko) | 2009-05-05 | 2017-12-22 | 노비뮨 에스 에이 | 항―il―17f 항체 및 이의 사용 방법 |
SG175891A1 (en) | 2009-05-08 | 2011-12-29 | Genentech Inc | Humanized anti-egfl7 antibodies and methods using same |
AT508569A1 (de) * | 2009-07-23 | 2011-02-15 | Affiris Ag | Pharmaceutical compound |
KR102126964B1 (ko) | 2009-11-11 | 2020-06-25 | 가니메드 파마슈티칼스 게엠베하 | 클라우딘 6 특이적 항체 |
EP2404936A1 (en) | 2010-07-06 | 2012-01-11 | Ganymed Pharmaceuticals AG | Cancer therapy using CLDN6 target-directed antibodies in vivo |
SI3026064T1 (sl) | 2011-05-13 | 2019-03-29 | Ganymed Pharmaceuticals Gmbh | Protitelesa za zdravljenje raka, ki eksprimira klavdin 6 |
EP3597666A3 (en) | 2011-07-01 | 2020-04-22 | NGM Biopharmaceuticals, Inc. | Compositions, uses and methods for treatment of metabolic disorders and diseases |
US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
NZ630484A (en) | 2012-11-28 | 2017-04-28 | Ngm Biopharmaceuticals Inc | Compositions and methods for treatment of metabolic disorders and diseases |
DK2938740T3 (da) | 2012-12-27 | 2022-06-20 | Ngm Biopharmaceuticals Inc | Kimære fgf19-peptider til anvendelse til behandling af galdesyrelidelser |
US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
CN110922467A (zh) * | 2013-01-17 | 2020-03-27 | 汉诺威医学院 | 用于治疗或预防疾病的因子1蛋白、因子2蛋白及其抑制剂 |
WO2015014376A1 (en) | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
BR112016002845A2 (pt) | 2013-08-12 | 2017-09-12 | Genentech Inc | composições e métodos para tratar condições associadas ao complemento |
BR112016009099A2 (pt) | 2013-10-28 | 2017-09-19 | Ngm Biopharmaceuticals Inc | Método para determinar se um indivíduo de teste tendo um distúrbio metabólico é um candidato para o tratamento com uma variante de fgf19, método para determinar se uma variante de fgf19 é um candidato para tratar um indivíduo de teste, uso de uma variante fgf19, modelo para determinar se uma variante de fgf19 é um candidato para prevenir uma doença |
CA2937898A1 (en) | 2014-01-24 | 2015-07-30 | Ngm Biopharmaceuticals, Inc. | Antibodies that bind to beta klotho and uses thereof |
TW201623337A (zh) | 2014-05-01 | 2016-07-01 | 建南德克公司 | 抗-因子d抗體變異體及其用途 |
US10398758B2 (en) | 2014-05-28 | 2019-09-03 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions |
WO2015195509A2 (en) | 2014-06-16 | 2015-12-23 | Ngm Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
US10517929B2 (en) | 2014-10-23 | 2019-12-31 | Ngm Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising FGF19 variants |
US10434144B2 (en) | 2014-11-07 | 2019-10-08 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders |
WO2017019957A2 (en) | 2015-07-29 | 2017-02-02 | Ngm Biopharmaceuticals, Inc. | Binding proteins and methods of use thereof |
JP2018534930A (ja) | 2015-10-30 | 2018-11-29 | ジェネンテック, インコーポレイテッド | 抗d因子抗体及びコンジュゲート |
US10654932B2 (en) | 2015-10-30 | 2020-05-19 | Genentech, Inc. | Anti-factor D antibody variant conjugates and uses thereof |
ES2871036T3 (es) | 2015-11-09 | 2021-10-28 | Ngm Biopharmaceuticals Inc | Método para el tratamiento de trastornos relacionados con ácidos biliares |
EP3503882A4 (en) | 2016-08-26 | 2020-07-29 | NGM Biopharmaceuticals, Inc. | METHOD FOR TREATING FIBROBLAST GROWTH FACTOR-19-MEDIATED CARCINOMAS AND TUMORS |
GB201906052D0 (en) | 2019-04-30 | 2019-06-12 | Int Centre For Genetic Engineering And Biotechnology | Proteins with cardioprotective activity |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002000690A2 (en) * | 2000-06-23 | 2002-01-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
WO2000053756A2 (en) * | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO1999010363A1 (en) * | 1997-08-29 | 1999-03-04 | Human Genome Sciences, Inc. | 29 human secreted proteins |
JP2002506615A (ja) * | 1998-02-27 | 2002-03-05 | 財団法人相模中央化学研究所 | 膜貫通ドメインを有するヒト蛋白質とそれをコードするdna |
NZ507435A (en) * | 1998-03-10 | 2003-12-19 | Genentech Inc | Novel polypeptides and nucleic acids with homology to cornichon |
JP2002509722A (ja) * | 1998-03-31 | 2002-04-02 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
CA2341767A1 (en) * | 1998-09-14 | 2000-03-23 | Genentech, Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
EP1135485B1 (en) * | 1998-12-01 | 2010-02-17 | Genentech, Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
AU2399300A (en) * | 1999-03-08 | 2000-09-28 | Genentech Inc. | Methods and compositions for inhibiting neoplastic cell growth |
KR100543857B1 (ko) * | 1999-09-01 | 2006-01-23 | 제넨테크, 인크. | 혈관신생 및 심혈관형성의 촉진 또는 억제 |
-
2001
- 2001-07-09 CA CA002416538A patent/CA2416538A1/en not_active Abandoned
- 2001-07-09 AU AU2001271973A patent/AU2001271973A1/en not_active Abandoned
- 2001-07-09 EP EP01951036A patent/EP1309685A2/en not_active Withdrawn
- 2001-07-09 JP JP2002514188A patent/JP2004516013A/ja not_active Withdrawn
- 2001-07-09 WO PCT/US2001/021735 patent/WO2002008284A2/en active Search and Examination
-
2008
- 2008-07-29 JP JP2008194764A patent/JP2009039119A/ja not_active Withdrawn
- 2008-07-29 JP JP2008194721A patent/JP2009039118A/ja not_active Withdrawn
- 2008-07-29 JP JP2008194678A patent/JP2009039117A/ja not_active Withdrawn
-
2011
- 2011-08-08 JP JP2011173336A patent/JP6033531B2/ja not_active Expired - Fee Related
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