JP2004512810A - 核酸に基づく遺伝子発現の調節剤 - Google Patents

核酸に基づく遺伝子発現の調節剤 Download PDF

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JP2004512810A
JP2004512810A JP2001520859A JP2001520859A JP2004512810A JP 2004512810 A JP2004512810 A JP 2004512810A JP 2001520859 A JP2001520859 A JP 2001520859A JP 2001520859 A JP2001520859 A JP 2001520859A JP 2004512810 A JP2004512810 A JP 2004512810A
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nucleic acid
acid molecule
enzymatic nucleic
rna
enzymatic
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JP2004512810A5 (enExample
Inventor
マクスウィゲン，ジェイムズ
ウスマン，ナシム
ブラット，ローレンス
ベイジェルマン，レオニド
バージン，アレックス
カーペイスキー，アレクサンダー
マチュリックーアダミック，ジャセンカ
スウィードラー，デイビッド
ドレイパー，ケネス
チョーリラ，バラート
スティンチコーム，ダン
ビュードリー，アンバー
ジネン，ショーン
ラグウィッグ，ジャノス
スプロート，ブライアン・エス
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Sirna Therapeutics Inc
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Sirna Therapeutics Inc
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Priority claimed from US09/474,432 external-priority patent/US6528640B1/en
Priority claimed from US09/476,387 external-priority patent/US6617438B1/en
Application filed by Sirna Therapeutics Inc filed Critical Sirna Therapeutics Inc
Publication of JP2004512810A publication Critical patent/JP2004512810A/ja
Publication of JP2004512810A5 publication Critical patent/JP2004512810A5/ja
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JP2001520859A 1999-08-31 2000-08-30 核酸に基づく遺伝子発現の調節剤 Pending JP2004512810A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US15171399P 1999-08-31 1999-08-31
US40664399A 1999-09-27 1999-09-27
US15646799P 1999-09-27 1999-09-27
US15623699P 1999-09-27 1999-09-27
US43643099A 1999-11-08 1999-11-08
US16910099P 1999-12-06 1999-12-06
US17361299P 1999-12-29 1999-12-29
US09/474,432 US6528640B1 (en) 1997-11-05 1999-12-29 Synthetic ribonucleic acids with RNAse activity
US09/476,387 US6617438B1 (en) 1997-11-05 1999-12-30 Oligoribonucleotides with enzymatic activity
US49882400A 2000-02-04 2000-02-04
US53102500A 2000-03-20 2000-03-20
US19776900P 2000-04-14 2000-04-14
US57822300A 2000-05-23 2000-05-23
US63638500A 2000-08-09 2000-08-09
PCT/US2000/023998 WO2001016312A2 (en) 1999-08-31 2000-08-30 Nucleic acid based modulators of gene expression

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JP2004512810A true JP2004512810A (ja) 2004-04-30
JP2004512810A5 JP2004512810A5 (enExample) 2005-01-06

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EP (1) EP1212416A2 (enExample)
JP (1) JP2004512810A (enExample)
CA (1) CA2403243A1 (enExample)
WO (1) WO2001016312A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4837555B2 (ja) * 2003-02-28 2011-12-14 アイシス ファーマシューティカルズ， インコーポレーテッド 成長ホルモン受容体の発現およびインスリン様成長因子の発現のモジュレーション
JP2013544251A (ja) * 2010-11-15 2013-12-12 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド アミロイド線維形成関連状態を処置するためのジペプチドアナログ
JP2015528013A (ja) * 2012-07-27 2015-09-24 ビアル−ポルテラ エ コンパニア，ソシエダッド アノニマ 置換ウレア化合物の合成方法
WO2015173208A3 (en) * 2014-05-15 2016-02-18 F. Hoffmann-La Roche Ag Oligomers and oligomer conjugates
US12378559B2 (en) 2018-11-02 2025-08-05 University Of Essex Enterprises Limited Enzymatic nucleic acid molecules

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528640B1 (en) * 1997-11-05 2003-03-04 Ribozyme Pharmaceuticals, Incorporated Synthetic ribonucleic acids with RNAse activity
US6617438B1 (en) * 1997-11-05 2003-09-09 Sirna Therapeutics, Inc. Oligoribonucleotides with enzymatic activity
US6482932B1 (en) * 1997-11-05 2002-11-19 Ribozyme Pharmaceuticals, Incorporated Nucleoside triphosphates and their incorporation into oligonucleotides
US7179796B2 (en) 2000-01-18 2007-02-20 Isis Pharmaceuticals, Inc. Antisense modulation of PTP1B expression
US20020055479A1 (en) * 2000-01-18 2002-05-09 Cowsert Lex M. Antisense modulation of PTP1B expression
US20030190635A1 (en) * 2002-02-20 2003-10-09 Mcswiggen James A. RNA interference mediated treatment of Alzheimer's disease using short interfering RNA
US7125660B2 (en) 2000-09-13 2006-10-24 Archemix Corp. Nucleic acid sensor molecules and methods of using same
US9994853B2 (en) 2001-05-18 2018-06-12 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
WO2003070983A1 (en) * 2002-02-20 2003-08-28 Sirna Therapeutics, Inc RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN KINASE C ALPHA (PKC-ALPHA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP1390472A4 (en) * 2001-05-29 2004-11-17 Sirna Therapeutics Inc NUCLEIC ACID TREATMENT OF DISEASES OR SIDES RELATED TO RAS, HER2 AND HIV LEVELS
CA2478681A1 (en) * 2001-10-22 2003-05-01 University Of Rochester Telomerase interference
US9657294B2 (en) 2002-02-20 2017-05-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
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