JP2004504063A5 - - Google Patents

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Publication number
JP2004504063A5
JP2004504063A5 JP2002514175A JP2002514175A JP2004504063A5 JP 2004504063 A5 JP2004504063 A5 JP 2004504063A5 JP 2002514175 A JP2002514175 A JP 2002514175A JP 2002514175 A JP2002514175 A JP 2002514175A JP 2004504063 A5 JP2004504063 A5 JP 2004504063A5
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JP
Japan
Prior art keywords
antibody
seq
polypeptide
mutation
mutant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002514175A
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English (en)
Japanese (ja)
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JP2004504063A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/021738 external-priority patent/WO2002008271A1/en
Publication of JP2004504063A publication Critical patent/JP2004504063A/ja
Publication of JP2004504063A5 publication Critical patent/JP2004504063A5/ja
Pending legal-status Critical Current

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JP2002514175A 2000-07-19 2001-07-10 新規線維芽細胞増殖因子(fgf23)および使用方法 Pending JP2004504063A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21913700P 2000-07-19 2000-07-19
PCT/US2001/021738 WO2002008271A1 (en) 2000-07-19 2001-07-10 Novel fibroblast growth factor (fgf23) and methods for use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008025528A Division JP2008194039A (ja) 2000-07-19 2008-02-05 新規線維芽細胞増殖因子(fgf23)および使用方法

Publications (2)

Publication Number Publication Date
JP2004504063A JP2004504063A (ja) 2004-02-12
JP2004504063A5 true JP2004504063A5 (cg-RX-API-DMAC7.html) 2008-03-27

Family

ID=22818027

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002514175A Pending JP2004504063A (ja) 2000-07-19 2001-07-10 新規線維芽細胞増殖因子(fgf23)および使用方法
JP2008025528A Pending JP2008194039A (ja) 2000-07-19 2008-02-05 新規線維芽細胞増殖因子(fgf23)および使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008025528A Pending JP2008194039A (ja) 2000-07-19 2008-02-05 新規線維芽細胞増殖因子(fgf23)および使用方法

Country Status (11)

Country Link
US (5) US7223563B2 (cg-RX-API-DMAC7.html)
EP (2) EP2184296A1 (cg-RX-API-DMAC7.html)
JP (2) JP2004504063A (cg-RX-API-DMAC7.html)
KR (2) KR20090036151A (cg-RX-API-DMAC7.html)
CN (1) CN1446227B (cg-RX-API-DMAC7.html)
AT (1) ATE461213T1 (cg-RX-API-DMAC7.html)
AU (2) AU7332301A (cg-RX-API-DMAC7.html)
CA (1) CA2418215A1 (cg-RX-API-DMAC7.html)
DE (1) DE60141582D1 (cg-RX-API-DMAC7.html)
ES (1) ES2340662T3 (cg-RX-API-DMAC7.html)
WO (1) WO2002008271A1 (cg-RX-API-DMAC7.html)

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US7094551B2 (en) 2002-09-17 2006-08-22 Zahradnik Richard J Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23
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US8012694B2 (en) 2006-09-14 2011-09-06 Immutopics, Inc. Assay for the detection of phosphorylated PTH
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US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
WO2009091556A2 (en) * 2008-01-17 2009-07-23 The General Hospital Corporation Diagnostic methods and kits using fibroblast growth factor-23
TW200936156A (en) 2008-01-28 2009-09-01 Novartis Ag Methods and compositions using Klotho-FGF fusion polypeptides
US8420088B2 (en) * 2008-01-28 2013-04-16 Novartis Ag Methods and compositions using FGF23 fusion polypeptides
CN103353532B (zh) * 2008-04-29 2016-05-11 诺瓦提斯公司 监测成纤维细胞生长因子受体的激酶活性的调节的方法及所述方法的应用
US8889621B2 (en) * 2009-10-30 2014-11-18 New York University Inhibiting binding of FGF23 to the binary FGFR-Klotho complex for the treatment of hypophosphatemia
US20110195077A1 (en) * 2010-01-29 2011-08-11 Novartis Ag Methods and compositions using fgf23 fusion ppolypeptides
WO2012029837A1 (ja) 2010-08-31 2012-03-08 協和メデックス株式会社 線維芽細胞増殖因子-23の測定方法及び測定試薬
WO2012055096A1 (zh) * 2010-10-27 2012-05-03 温州医学院生物与天然药物开发中心有限公司 抗fgf-23抗体的制备方法及用途
US20140294820A1 (en) 2011-06-24 2014-10-02 University Of Miami Fibroblast growth factor receptor inhibition for the treatment of disease
LT2726511T (lt) 2011-07-01 2019-11-11 Ngm Biopharmaceuticals Inc Kompozicijos, panaudojimai ir būdai, skirti metabolinių sutrikimų ir ligų gydymui
WO2013027191A1 (en) 2011-08-25 2013-02-28 Novartis Ag Methods and compositions using fgf23 fusion polypeptides
US9657075B2 (en) 2012-06-07 2017-05-23 New York University Chimeric fibroblast growth factor 23 proteins and methods of use
AU2013352363B2 (en) 2012-11-28 2018-04-12 Ngm Biopharmaceuticals, Inc. Compositions and methods for treatment of metabolic disorders and diseases
US9290557B2 (en) 2012-11-28 2016-03-22 Ngm Biopharmaceuticals, Inc. Compositions comprising variants and fusions of FGF19 polypeptides
US9273107B2 (en) 2012-12-27 2016-03-01 Ngm Biopharmaceuticals, Inc. Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
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US9550820B2 (en) 2013-02-22 2017-01-24 New York University Chimeric fibroblast growth factor 23/fibroblast growth factor 19 proteins and methods of use
JP6479775B2 (ja) * 2013-09-20 2019-03-06 ロンザ リミテッドLonza Limited 細胞の核リプログラミングのための方法
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US10464979B2 (en) 2014-03-28 2019-11-05 New York University FGF23 c-tail fusion proteins
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US10434144B2 (en) 2014-11-07 2019-10-08 Ngm Biopharmaceuticals, Inc. Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
CN107810201A (zh) 2014-12-04 2018-03-16 诺华股份有限公司 使用klotho变体多肽的方法和组合物
CN105699664A (zh) * 2015-04-13 2016-06-22 陈柏龄 Fgf23检测试剂盒及其制备方法
AU2016284696B2 (en) * 2015-06-25 2021-10-28 Amyris, Inc. Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds
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WO2020047475A1 (en) * 2018-08-30 2020-03-05 The Uab Research Foundation Drug screening for fgf23-fgfr4 inhibitors
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