JP2004531270A5 - - Google Patents

Download PDF

Info

Publication number
JP2004531270A5
JP2004531270A5 JP2003507235A JP2003507235A JP2004531270A5 JP 2004531270 A5 JP2004531270 A5 JP 2004531270A5 JP 2003507235 A JP2003507235 A JP 2003507235A JP 2003507235 A JP2003507235 A JP 2003507235A JP 2004531270 A5 JP2004531270 A5 JP 2004531270A5
Authority
JP
Japan
Prior art keywords
monoclonal antibody
antibody
kda
antigen
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003507235A
Other languages
English (en)
Japanese (ja)
Other versions
JP4455876B2 (ja
JP2004531270A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/019646 external-priority patent/WO2003000848A2/en
Publication of JP2004531270A publication Critical patent/JP2004531270A/ja
Publication of JP2004531270A5 publication Critical patent/JP2004531270A5/ja
Application granted granted Critical
Publication of JP4455876B2 publication Critical patent/JP4455876B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2003507235A 2001-06-22 2002-06-21 肝移植細胞、アッセイ法、およびその使用法 Expired - Fee Related JP4455876B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30053501P 2001-06-22 2001-06-22
PCT/US2002/019646 WO2003000848A2 (en) 2001-06-22 2002-06-21 Liver engrafting cells, assays, and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009090608A Division JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Publications (3)

Publication Number Publication Date
JP2004531270A JP2004531270A (ja) 2004-10-14
JP2004531270A5 true JP2004531270A5 (cg-RX-API-DMAC7.html) 2006-01-05
JP4455876B2 JP4455876B2 (ja) 2010-04-21

Family

ID=23159503

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003507235A Expired - Fee Related JP4455876B2 (ja) 2001-06-22 2002-06-21 肝移植細胞、アッセイ法、およびその使用法
JP2009090608A Withdrawn JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009090608A Withdrawn JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Country Status (11)

Country Link
US (3) US7211404B2 (cg-RX-API-DMAC7.html)
EP (3) EP1956078A3 (cg-RX-API-DMAC7.html)
JP (2) JP4455876B2 (cg-RX-API-DMAC7.html)
CN (2) CN1665920A (cg-RX-API-DMAC7.html)
AT (1) ATE371018T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002315392B2 (cg-RX-API-DMAC7.html)
CA (1) CA2451637C (cg-RX-API-DMAC7.html)
DE (1) DE60221987T2 (cg-RX-API-DMAC7.html)
DK (1) DK1406998T3 (cg-RX-API-DMAC7.html)
ES (1) ES2292772T3 (cg-RX-API-DMAC7.html)
WO (1) WO2003000848A2 (cg-RX-API-DMAC7.html)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050089518A1 (en) * 2001-12-07 2005-04-28 Clarke Michael F. Prospective identification and characterization of breast cancer stem cells
US8044259B2 (en) 2000-08-03 2011-10-25 The Regents Of The University Of Michigan Determining the capability of a test compound to affect solid tumor stem cells
US6984522B2 (en) * 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US7838292B1 (en) * 2001-03-29 2010-11-23 University Of Louisville Research Foundation, Inc. Methods for obtaining adult human olfactory progenitor cells
EP1956078A3 (en) 2001-06-22 2008-10-29 StemCells, Inc. Liver engrafting cells, assays, and uses thereof
US7780993B2 (en) * 2001-09-07 2010-08-24 Yeda Research And Development Co. Ltd. Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts
US20040136972A1 (en) * 2001-09-07 2004-07-15 Yeda Research And Development Co. Ltd. Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
IL165425A0 (en) * 2004-11-28 2006-01-15 Yeda Res & Dev Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
WO2005005601A2 (en) * 2003-06-09 2005-01-20 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20050014217A1 (en) * 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
US20050232927A1 (en) * 2004-02-03 2005-10-20 The Regents Of The University Of Michigan Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
CN101014855A (zh) * 2004-08-20 2007-08-08 第一化学药品株式会社 药物在人体中的肝代谢和肝功能的预测方法
US20060252073A1 (en) * 2005-04-18 2006-11-09 Regents Of The University Of Michigan Compositions and methods for the treatment of cancer
AU2006259583A1 (en) * 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20070099209A1 (en) * 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
WO2007053648A2 (en) * 2005-10-31 2007-05-10 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
ES2547421T3 (es) 2005-10-31 2015-10-06 Oncomed Pharmaceuticals, Inc. Composiciones y métodos para diagnosticar y tratar el cáncer
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
CA2634510C (en) 2005-12-21 2018-01-09 Universite Catholique De Louvain Isolated liver stem cells
US20080019961A1 (en) * 2006-02-21 2008-01-24 Regents Of The University Of Michigan Hedgehog signaling pathway antagonist cancer treatment
US8148147B2 (en) 2007-01-24 2012-04-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing pancreatic cancer
WO2008151283A1 (en) * 2007-06-05 2008-12-11 Oregon Health & Science University Method of expanding human hepatocytes in vivo
SG183067A1 (en) * 2007-07-20 2012-08-30 Cellartis Ab A novel population of hepatocytes derived via definitive endoderm (de-hep) from human blastocysts derived stem cells
WO2009075856A1 (en) * 2007-12-10 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Regenerative dot cells
WO2009111778A2 (en) * 2008-03-07 2009-09-11 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Lymph nodes as a site for regeneration
KR101711672B1 (ko) 2008-09-26 2017-03-03 온코메드 파마슈티칼스, 인크. 프리즐드 결합 작용제 및 그의 용도
US20100227393A1 (en) * 2009-03-06 2010-09-09 Eric Lagasse Liver stem cells: isolation of hepatic progenitor cells from the human gall bladder
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Ｗｎｔ拮抗劑及治療和篩選方法
JPWO2011102532A1 (ja) * 2010-02-16 2013-06-17 国立大学法人九州大学 誘導肝細胞
CA2794674A1 (en) 2010-04-01 2011-10-06 Oncomed Pharmaceuticals, Inc. Frizzled-binding agents and uses thereof
AU2013334790A1 (en) 2012-10-23 2015-04-30 Oncomed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using Wnt pathway-binding agents
WO2014121196A1 (en) 2013-02-04 2014-08-07 Oncomed Pharmaceuticals, Inc. Methods and monitoring of treatment with a wnt pathway inhibitor
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
US20160129047A1 (en) 2013-07-05 2016-05-12 Université Catholique de Louvain Conditioned medium from human adult liver stem cells and its use in the treatment of liver disorders
JP6672603B2 (ja) * 2015-03-27 2020-03-25 株式会社豊田中央研究所 物質と細胞との間の作用の評価方法
JP6813514B2 (ja) 2015-06-23 2021-01-13 ザ ジャクソン ラボラトリーＴｈｅ Ｊａｃｋｓｏｎ Ｌａｂｏｒａｔｏｒｙ 患者由来異種移植片を用いた非ｈｌａマッチヒト化ｎｓｇマウスモデル
JP2020508298A (ja) * 2017-02-17 2020-03-19 ユニバーシティ オブ ピッツバーグ −オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 移植、組織再生、器官形成及び複数の組織に対する機能のための部位としての脂肪関連リンパ球集積（ｆａｔ−ａｓｓｏｃｉａｔｅｄ ｌｙｍｐｈｏｉｄ ｃｌｕｓｔｅｒ）
EP3784224A4 (en) * 2018-04-27 2022-08-03 The Regents of the University of California DE NOVO FORMATION OF THE BILIARY SYSTEM BY HEPATOCYTE TRANSDIFFERENTIATION
WO2021207801A1 (en) * 2020-04-17 2021-10-21 The Council Of The Queensland Institute Of Medical Research Immune cells with enhanced function
WO2023060186A1 (en) * 2021-10-07 2023-04-13 Hepatx Corporation Methods of tracking donor cells in a recipient
WO2023132371A1 (ja) 2022-01-07 2023-07-13 インテグリカルチャー株式会社 肝臓由来の細胞の培養方法および肝臓由来の細胞を含む培養系

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6069005A (en) 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
CA2115140A1 (en) 1991-08-07 1993-02-18 Lola M. Reid Proliferation of hepatocyte precursors
KR950703640A (ko) * 1992-10-09 1995-09-20 가일 케이,나우톤. 간 보존 세포(liver reserve cells)
US5459037A (en) 1993-11-12 1995-10-17 The Scripps Research Institute Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
ES2260759T3 (es) * 1993-11-19 2006-11-01 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Hepatoblastos y metodo de aislamiento de los mismos.
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
EP0833893A1 (en) 1995-06-06 1998-04-08 Whitehead Institute For Biomedical Research Isolation of mammalian hematopoietic stem cells
AU6223296A (en) * 1995-06-07 1996-12-30 Novartis Ag Methods for obtaining compositions enriched for hematopoieti c stem cells and antibodies for use therein
US5776683A (en) 1996-07-11 1998-07-07 California Pacific Medical Center Methods for identifying genes amplified in cancer cells
US6046036A (en) * 1996-10-25 2000-04-04 Advanced Research And Technology Institute DNA sequences encoding fusions of DNA repair proteins and uses thereof
US6129911A (en) * 1998-07-10 2000-10-10 Rhode Island Hospital, A Lifespan Partner Liver stem cell
US6242666B1 (en) * 1998-12-16 2001-06-05 The Scripps Research Institute Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
AU780256B2 (en) 1999-02-12 2005-03-10 Boco Silicon Valley, Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
US6468794B1 (en) 1999-02-12 2002-10-22 Stemcells, Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
ATE510905T1 (de) 2000-10-03 2011-06-15 Univ North Carolina Verfahren zur isolierung von bipotenten lebervorläuferzellen
EP1559777A1 (en) 2001-04-24 2005-08-03 Hokkaido Technology Licensing Office Co., Ltd. Process for maturating small heptocyte-rich colonies into liver tissue
EP1956078A3 (en) * 2001-06-22 2008-10-29 StemCells, Inc. Liver engrafting cells, assays, and uses thereof
US8707400B2 (en) 2007-01-22 2014-04-22 Apple Inc. System and method for implementing an extended authentication and authorization credential store

Similar Documents

Publication Publication Date Title
JP2004531270A5 (cg-RX-API-DMAC7.html)
JP2002503495A5 (cg-RX-API-DMAC7.html)
JP2004502409A5 (cg-RX-API-DMAC7.html)
NZ547157A (en) Interferon Alpha Antibodies and their uses
CA2406240C (en) Hcv anti-core monoclonal antibodies
CA2469833A1 (en) Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them
NZ616992A (en) Anti-ilt7 antibody
JP2004536568A5 (cg-RX-API-DMAC7.html)
RU2011140509A (ru) Гетеродимерные полипептиды il-17a/f и возможности их лечебного применения
NZ587198A (en) Monoclonal antibodies against the rgm a protein and uses thereof
WO2005018424A3 (en) Antibodies specific for fibrillar amyloid and a procedure to detect fibrillar amyloid deposits
WO2003100033A3 (en) ANTI-αvβ6 ANTIBODIES
CA2368734A1 (en) Method for preparing monoclonal antibody
FI3718564T3 (fi) Uusia anti-IL 13 -vasta-aineita ja niiden käyttöjä
JP2002524024A5 (cg-RX-API-DMAC7.html)
RU2004107695A (ru) Способы удаления амилоида с помощью анти-амилоидных антител
EA200700083A1 (ru) Антитела, направленные против бета-амилоидного пептида, и способы их применения
JP2004504063A5 (cg-RX-API-DMAC7.html)
CA2180425A1 (en) Purified primate ctla-8 antigens and related reagents
AU6760700A (en) Ovarian cancer cell and myeloma cell surface glycoproteins, antibodies thereto, and uses thereof
FR2746398A1 (fr) Anticorps specifique de staphylococcus aureaus, et utilisations
IL116617A0 (en) Monoclonal antibodies specific for advanced glycosylation endproducts in biological samples
NZ547629A (en) Antibodies binding to conformationally discriminating epitopes of human IGG Fc receptor IIb and IIb
CA2457362A1 (en) Human monoclonal rabies virus neutralizing antibodies, and methods for making and using the same
AU2003283240A1 (en) Antibody for isolating and/or identifying mesenchymal stem cells and method for isolating and/or identifying mesenchymal stem cells