JP2003528144A5 - - Google Patents

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Publication number
JP2003528144A5
JP2003528144A5 JP2001570263A JP2001570263A JP2003528144A5 JP 2003528144 A5 JP2003528144 A5 JP 2003528144A5 JP 2001570263 A JP2001570263 A JP 2001570263A JP 2001570263 A JP2001570263 A JP 2001570263A JP 2003528144 A5 JP2003528144 A5 JP 2003528144A5
Authority
JP
Japan
Prior art keywords
receptor
substance
carboxy
primary headache
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001570263A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003528144A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2000/001138 external-priority patent/WO2001072302A1/en
Publication of JP2003528144A publication Critical patent/JP2003528144A/ja
Publication of JP2003528144A5 publication Critical patent/JP2003528144A5/ja
Pending legal-status Critical Current

Links

JP2001570263A 2000-03-24 2000-03-24 頭痛治療のためのプロスタノイドep4受容体アンタゴニストの使用およびそのアンタゴニストについてのアッセイ Pending JP2003528144A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2000/001138 WO2001072302A1 (en) 2000-03-24 2000-03-24 Use of prostanoid ep4 receptor antagonists for the treatment of headache and assays for such antagonists

Publications (2)

Publication Number Publication Date
JP2003528144A JP2003528144A (ja) 2003-09-24
JP2003528144A5 true JP2003528144A5 (https=) 2007-05-10

Family

ID=9883925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001570263A Pending JP2003528144A (ja) 2000-03-24 2000-03-24 頭痛治療のためのプロスタノイドep4受容体アンタゴニストの使用およびそのアンタゴニストについてのアッセイ

Country Status (8)

Country Link
EP (1) EP1267867B1 (https=)
JP (1) JP2003528144A (https=)
AT (1) ATE395058T1 (https=)
AU (2) AU3445100A (https=)
CA (1) CA2402099C (https=)
DE (1) DE60038902D1 (https=)
DK (1) DK1267867T3 (https=)
WO (1) WO2001072302A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005511562A (ja) * 2001-10-31 2005-04-28 メディカル リサーチ カウンシル 月経困難症及び月経過多の治療のためのプロスタグランジンレセプターep2及び/又はep4のアンタゴニスト
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
CA2679175C (en) * 2007-02-26 2015-01-13 Merck Frosst Canada Ltd. Indole and indoline cyclopropyl amide derivatives as ep4 receptor antagonists
US20150126573A1 (en) 2012-05-09 2015-05-07 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and pharmaceutical compositions for prevention or treatment of chronic obstructive pulmonary disease
CR20180323A (es) 2015-11-20 2018-08-06 Idorsia Pharmaceuticals Ltd Derivados de indol n-sustituídos como moduladores de los receptores de pge2
TWI768043B (zh) 2017-05-18 2022-06-21 瑞士商愛杜西亞製藥有限公司 N-取代吲哚衍生物
US11839613B2 (en) 2017-05-18 2023-12-12 Idorsia Pharmaceuticals Ltd Pyrimidine derivatives as PGE2 receptor modulators
PE20191814A1 (es) 2017-05-18 2019-12-27 Idorsia Pharmaceuticals Ltd Derivados de pirimidina como moduladores del receptor de pge2
TW201900179A (zh) 2017-05-18 2019-01-01 瑞士商愛杜西亞製藥有限公司 作為pge2受體調節劑之苯并呋喃及苯并噻吩衍生物
KR102612140B1 (ko) 2017-05-18 2023-12-08 이도르시아 파마슈티컬스 리미티드 피리미딘 유도체

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1046714C (zh) * 1993-12-20 1999-11-24 藤泽药品工业株式会社 二芳基噁唑衍生物及其制法、应用和药物组合物
AUPO713297A0 (en) * 1997-06-02 1997-06-26 Fujisawa Pharmaceutical Co., Ltd. Oxazole compound
GB9720270D0 (en) * 1997-09-25 1997-11-26 Pharmagene Lab Limited Medicaments for the treatment of migraine
AU6836200A (en) * 1999-08-10 2001-03-05 Glaxo Group Limited Use of ep4 receptor ligands in the treatment of, inter alia, neuropathic pain and colon cancer

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