JP2003527606A5 - - Google Patents
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- JP2003527606A5 JP2003527606A5 JP2001568086A JP2001568086A JP2003527606A5 JP 2003527606 A5 JP2003527606 A5 JP 2003527606A5 JP 2001568086 A JP2001568086 A JP 2001568086A JP 2001568086 A JP2001568086 A JP 2001568086A JP 2003527606 A5 JP2003527606 A5 JP 2003527606A5
- Authority
- JP
- Japan
- Prior art keywords
- liquid
- analyte
- capture
- solid
- bound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 2
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- PCMORTLOPMLEFB-ONEGZZNKSA-N sinapic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC(OC)=C1O PCMORTLOPMLEFB-ONEGZZNKSA-N 0.000 description 2
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- CDUQMGQIHYISOP-UHFFFAOYSA-N 2-cyano-3-phenylprop-2-enoic acid Chemical compound OC(=O)C(C#N)=CC1=CC=CC=C1 CDUQMGQIHYISOP-UHFFFAOYSA-N 0.000 description 1
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- QWAXKHKRTORLEM-UGJKXSETSA-N saquinavir Chemical compound C([C@@H]([C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)C=1N=C2C=CC=CC2=CC=1)C1=CC=CC=C1 QWAXKHKRTORLEM-UGJKXSETSA-N 0.000 description 1
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- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- PCMORTLOPMLEFB-UHFFFAOYSA-N sinapinic acid Natural products COC1=CC(C=CC(O)=O)=CC(OC)=C1O PCMORTLOPMLEFB-UHFFFAOYSA-N 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
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- WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19033600P | 2000-03-16 | 2000-03-16 | |
| US60/190,336 | 2000-03-16 | ||
| PCT/SE2001/000531 WO2001069258A1 (en) | 2000-03-16 | 2001-03-14 | Method for capturing analytes eluted from surface-bound ligands |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003527606A JP2003527606A (ja) | 2003-09-16 |
| JP2003527606A5 true JP2003527606A5 (https=) | 2011-05-12 |
| JP4860085B2 JP4860085B2 (ja) | 2012-01-25 |
Family
ID=22700919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001568086A Expired - Lifetime JP4860085B2 (ja) | 2000-03-16 | 2001-03-14 | 表面結合リガンドから溶出された分析物を捕捉するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6503760B2 (https=) |
| EP (1) | EP1264179B1 (https=) |
| JP (1) | JP4860085B2 (https=) |
| AT (1) | ATE335202T1 (https=) |
| AU (1) | AU2001242928A1 (https=) |
| DE (1) | DE60121923T2 (https=) |
| WO (1) | WO2001069258A1 (https=) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4860085B2 (ja) * | 2000-03-16 | 2012-01-25 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 表面結合リガンドから溶出された分析物を捕捉するための方法 |
| US7126688B2 (en) * | 2000-07-11 | 2006-10-24 | Maven Technologies, Llc | Microarray scanning |
| US6833920B2 (en) | 2000-07-11 | 2004-12-21 | Maven Technologies Llc | Apparatus and method for imaging |
| US7518724B2 (en) * | 2000-07-11 | 2009-04-14 | Maven Technologies | Image acquisition, processing, and display |
| US6594011B1 (en) | 2000-07-11 | 2003-07-15 | Maven Technologies, Llc | Imaging apparatus and method |
| US7193711B2 (en) * | 2000-07-11 | 2007-03-20 | Maven Technologies, Llc | Imaging method and apparatus |
| US7023547B2 (en) * | 2000-07-11 | 2006-04-04 | Maven Technologies, Llc | Apparatus including a biochip for imaging of biological samples and method |
| CA2474469A1 (en) * | 2002-01-28 | 2003-08-07 | Mds Proteomics, Inc. | Chemical proteomics |
| US20030166007A1 (en) * | 2002-01-28 | 2003-09-04 | Mds Proteomics Inc. | Chemical proteomics |
| AU2003231731A1 (en) * | 2002-04-15 | 2003-11-03 | American National Red Cross | Method for detecting ligands and targets in a mixture |
| US6821744B2 (en) * | 2002-10-29 | 2004-11-23 | Roche Diagnostics Operations, Inc. | Method, assay, and kit for quantifying HIV protease inhibitors |
| JPWO2004051231A1 (ja) * | 2002-11-29 | 2006-04-06 | 日本電気株式会社 | 分離装置および分離方法 |
| US7736909B2 (en) | 2003-01-09 | 2010-06-15 | Board Of Regents, The University Of Texas System | Methods and compositions comprising capture agents |
| US7483140B1 (en) | 2004-12-10 | 2009-01-27 | University Of Central Florida Research Foundation, Inc. | Micro integrated planar optical waveguide type SPR sensor |
| US7611908B2 (en) | 2005-05-02 | 2009-11-03 | Bioscale, Inc. | Method and apparatus for therapeutic drug monitoring using an acoustic device |
| US7300631B2 (en) * | 2005-05-02 | 2007-11-27 | Bioscale, Inc. | Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles |
| US7648844B2 (en) * | 2005-05-02 | 2010-01-19 | Bioscale, Inc. | Method and apparatus for detection of analyte using an acoustic device |
| US7749445B2 (en) * | 2005-05-02 | 2010-07-06 | Bioscale, Inc. | Method and apparatus for analyzing bioprocess fluids |
| JP2006313091A (ja) * | 2005-05-06 | 2006-11-16 | Fuji Photo Film Co Ltd | 結合物質回収方法及び装置 |
| EP1943500A4 (en) | 2005-09-30 | 2013-01-16 | Fujifilm Corp | DETECTION SYSTEM |
| JP4768417B2 (ja) * | 2005-11-28 | 2011-09-07 | 富士フイルム株式会社 | バイオセンサー |
| US7867783B2 (en) * | 2007-02-22 | 2011-01-11 | Maven Technologies, Llc | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
| US7863037B1 (en) | 2007-04-04 | 2011-01-04 | Maven Technologies, Llc | Ligand binding assays on microarrays in closed multiwell plates |
| US20090041633A1 (en) * | 2007-05-14 | 2009-02-12 | Dultz Shane C | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
| US7799558B1 (en) | 2007-05-22 | 2010-09-21 | Dultz Shane C | Ligand binding assays on microarrays in closed multiwell plates |
| US8354280B2 (en) * | 2007-09-06 | 2013-01-15 | Bioscale, Inc. | Reusable detection surfaces and methods of using same |
| US7981664B1 (en) | 2008-05-22 | 2011-07-19 | Maven Technologies, Llc | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
| US8039270B2 (en) * | 2008-05-22 | 2011-10-18 | Maven Technologies, Llc | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
| EP2128617A1 (en) * | 2008-05-27 | 2009-12-02 | Koninklijke Philips Electronics N.V. | Device and methods for detecting analytes in saliva |
| BRPI1013012A2 (pt) | 2009-06-02 | 2016-10-18 | Opko Health Inc | identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas |
| WO2011047257A1 (en) | 2009-10-16 | 2011-04-21 | The Board Of Regents Of The University Of Texas System | Compositions and methods for producing cyclic peptoid libraries |
| US8355133B2 (en) * | 2009-12-30 | 2013-01-15 | Maven Technologies, Llc | Biological testing with sawtooth-shaped prisms |
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| US11885952B2 (en) | 2018-07-30 | 2024-01-30 | Essenlix Corporation | Optics, device, and system for assaying and imaging |
| WO2020225971A1 (ja) * | 2019-05-08 | 2020-11-12 | 株式会社日立ハイテク | 自動分析装置の前処理方法 |
| EP4089401B1 (de) * | 2021-05-10 | 2024-11-06 | Siemens Aktiengesellschaft | Messeinrichtung und verfahren zur messung von mindestens zwei verschiedenen komponenten eines fluids mittels ramanstreuung und chemilumineszenz |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5236826A (en) * | 1985-12-10 | 1993-08-17 | Murex Corporation | Immunoassay for the detection or quantitation of an analyte |
| US5750338A (en) * | 1986-10-23 | 1998-05-12 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
| US5236849A (en) * | 1987-08-11 | 1993-08-17 | Eiji Ishikawa | Method of high sensitivity immunoassay |
| GB8822180D0 (en) * | 1988-09-21 | 1988-10-26 | Glaverbel | Separation of product of biological process from fluid medium |
| JPH0466871A (ja) * | 1990-07-07 | 1992-03-03 | Eiji Ishikawa | 高感度な免疫測定法 |
| US5312730A (en) * | 1992-05-27 | 1994-05-17 | Ciba Corning Diagnostics Corp. | Immune complex transfer with lypophilic bridge |
| SE9201976D0 (sv) * | 1992-06-26 | 1992-06-26 | Tektolit Ab Haakan Eriksson | En metod foer att adsorbera proteiner och peptider till hydrofoba zeoliter |
| JPH08503698A (ja) * | 1992-10-02 | 1996-04-23 | ザ ゼネラル ホスピタル コーポレーション | アミノ酸模倣物を溶出試薬として用いる親和精製方法 |
| US5395587A (en) * | 1993-07-06 | 1995-03-07 | Smithkline Beecham Corporation | Surface plasmon resonance detector having collector for eluted ligate |
| US5445936A (en) * | 1993-09-15 | 1995-08-29 | Ciba Corning Diagnostics Corp. | Method for non-competitive binding assays |
| DE69422604T2 (de) * | 1994-03-08 | 2000-06-08 | Zeptosens Ag, Witterwil | Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren |
| JPH08178926A (ja) * | 1994-10-25 | 1996-07-12 | Sumitomo Pharmaceut Co Ltd | イムノアッセイプレートおよびその用途 |
| AU4117696A (en) * | 1994-11-24 | 1996-06-17 | Unipath Limited | Recovery of and uses of specific binding agents |
| JPH08304397A (ja) * | 1995-05-11 | 1996-11-22 | Sumitomo Pharmaceut Co Ltd | 病原体感染の検出方法 |
| US5756717A (en) * | 1995-05-24 | 1998-05-26 | Perseptive Biosystems, Inc | Protein imaging |
| GB9518429D0 (en) * | 1995-09-08 | 1995-11-08 | Pharmacia Biosensor | A rapid method for providing kinetic and structural data in molecular interaction analysis |
| CA2245714A1 (en) * | 1996-02-09 | 1997-08-14 | Martin Thomas French | Assay apparatus |
| WO1997044664A1 (en) * | 1996-05-23 | 1997-11-27 | Unilever Plc | Improvements in or relating to specific binding assays |
| ATE317979T1 (de) * | 1996-12-19 | 2006-03-15 | Dade Behring Marburg Gmbh | Immundissoziation zur verbesserung der immunchemischen bestimmung eines analyten |
| US6025197A (en) * | 1997-03-19 | 2000-02-15 | Zymogenetics, Inc. | Secreted salivary zsig32 polypeptides |
| US6289286B1 (en) * | 1998-05-29 | 2001-09-11 | Biacore Ab | Surface regeneration of biosensors and characterization of biomolecules associated therewith |
| JP3829491B2 (ja) * | 1998-08-27 | 2006-10-04 | 株式会社日立製作所 | プローブチップ、プローブチップ作成方法、試料検出方法、及び試料検出装置 |
| US6127129A (en) * | 1999-05-04 | 2000-10-03 | Wisconsin Alumni Research Foundation | Process to create biomolecule and/or cellular arrays on metal surfaces and product produced thereby |
| JP4860085B2 (ja) * | 2000-03-16 | 2012-01-25 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 表面結合リガンドから溶出された分析物を捕捉するための方法 |
-
2001
- 2001-03-14 JP JP2001568086A patent/JP4860085B2/ja not_active Expired - Lifetime
- 2001-03-14 DE DE60121923T patent/DE60121923T2/de not_active Expired - Lifetime
- 2001-03-14 AT AT01915984T patent/ATE335202T1/de not_active IP Right Cessation
- 2001-03-14 EP EP01915984A patent/EP1264179B1/en not_active Expired - Lifetime
- 2001-03-14 WO PCT/SE2001/000531 patent/WO2001069258A1/en not_active Ceased
- 2001-03-14 AU AU2001242928A patent/AU2001242928A1/en not_active Abandoned
- 2001-03-16 US US09/810,937 patent/US6503760B2/en not_active Expired - Fee Related
-
2002
- 2002-11-15 US US10/295,709 patent/US6844201B2/en not_active Expired - Lifetime
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