JP2003522112A5 - - Google Patents
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- Publication number
- JP2003522112A5 JP2003522112A5 JP2000578009A JP2000578009A JP2003522112A5 JP 2003522112 A5 JP2003522112 A5 JP 2003522112A5 JP 2000578009 A JP2000578009 A JP 2000578009A JP 2000578009 A JP2000578009 A JP 2000578009A JP 2003522112 A5 JP2003522112 A5 JP 2003522112A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- anxiety
- disorder
- tofisopam
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10580398P | 1998-10-27 | 1998-10-27 | |
| US60/105,803 | 1998-10-27 | ||
| PCT/US1999/025040 WO2000024400A1 (en) | 1998-10-27 | 1999-10-27 | Use of optically pure (r)-tofisopam for treating and preventing anxiety disorders and composition thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007136619A Division JP2007211028A (ja) | 1998-10-27 | 2007-05-23 | 不安障害の処置および予防への光学的に純粋な(r)−トフィソパムの使用およびその組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003522112A JP2003522112A (ja) | 2003-07-22 |
| JP2003522112A5 true JP2003522112A5 (https=) | 2007-02-01 |
Family
ID=22307874
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000578009A Pending JP2003522112A (ja) | 1998-10-27 | 1999-10-27 | 不安障害の処置および予防への光学的に純粋な(r)−トフィソパムの使用およびその組成物 |
| JP2007136619A Withdrawn JP2007211028A (ja) | 1998-10-27 | 2007-05-23 | 不安障害の処置および予防への光学的に純粋な(r)−トフィソパムの使用およびその組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007136619A Withdrawn JP2007211028A (ja) | 1998-10-27 | 2007-05-23 | 不安障害の処置および予防への光学的に純粋な(r)−トフィソパムの使用およびその組成物 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1124556B1 (https=) |
| JP (2) | JP2003522112A (https=) |
| AT (1) | ATE269705T1 (https=) |
| AU (1) | AU1451900A (https=) |
| BR (1) | BR9914899A (https=) |
| CA (1) | CA2348281A1 (https=) |
| DE (1) | DE69918322T2 (https=) |
| DK (1) | DK1124556T3 (https=) |
| ES (1) | ES2224751T3 (https=) |
| GB (1) | GB2367748A (https=) |
| HK (2) | HK1046500A1 (https=) |
| IL (2) | IL142803A0 (https=) |
| NZ (1) | NZ511744A (https=) |
| PT (1) | PT1124556E (https=) |
| WO (1) | WO2000024400A1 (https=) |
| ZA (1) | ZA200103376B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6649607B2 (en) | 2001-05-18 | 2003-11-18 | Vela Pharmaceuticals, Inc. | Compositions and methods for treating or preventing convulsions or seizures |
| US20030232805A1 (en) * | 2002-04-24 | 2003-12-18 | Cypress Bioscience, Inc. | Prevention and treatment of functional somatic disorders, including stress-related disorders |
| CA2510275A1 (en) * | 2002-12-03 | 2004-08-19 | Vela Pharmaceuticals, Inc. | Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof |
| US6864251B2 (en) * | 2002-12-03 | 2005-03-08 | Vela Pharmaceuticals, Inc. | Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines |
| US7022700B2 (en) | 2002-12-03 | 2006-04-04 | Vela Pharmaceuticals, Inc. | Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines |
| US6638928B1 (en) * | 2002-12-03 | 2003-10-28 | Vela Pharmaceuticals, Inc. | Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines |
| AU2003293405A1 (en) | 2002-12-03 | 2004-06-23 | Vela Pharmaceuticals, Inc. | Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof |
| CA2525273C (en) * | 2003-05-16 | 2012-04-17 | Vela Pharmaceuticals, Inc. | Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (r) 2,3-benzodiazepine |
| EP1689408A4 (en) * | 2003-12-03 | 2010-03-03 | Vela Acquisition Corp | TREATMENT OF INFLAMMATORY DISORDERS OF EPITHELIUM USING LOW DOSE 2,3-BENZODIAZEPINES |
| FR2870539B1 (fr) * | 2004-05-19 | 2006-08-04 | Greenpharma Sa Sa | Nouvelles methodes et medicaments |
| US7541355B2 (en) | 2005-05-23 | 2009-06-02 | Vela Acquisition Corporation | Conversion process for 2,3-benzodiazepine enantiomers |
| CN102836162A (zh) * | 2012-04-10 | 2012-12-26 | 珠海亿邦制药股份有限公司 | 一种以托非索泮为活性成分的口服固体制剂及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK118660B (da) * | 1966-12-09 | 1970-09-21 | Egyt Gyogyszervegyeszeti Gyar | Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid. |
| ZA712798B (en) * | 1970-11-06 | 1972-02-23 | Egyt Gyogyszervegyeszeti Gyar | New,pharmaceutically active 2,3-diazabicyclo(5.4.0)undecapentaene derivative and process for preparing same |
| HU178516B (en) * | 1978-05-05 | 1982-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing enanthiomeres of 1-bracket-3,4-dimethoxy-phenyl-bracket closed-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine and pharmacologically acceptable soles of the /-/-enanthiomere |
| HU209530B (en) * | 1988-08-31 | 1994-07-28 | Magnezitipari Muevek Rt | Process for manufacturing of cromit-like, fire resistant materials |
-
1999
- 1999-10-27 AU AU14519/00A patent/AU1451900A/en not_active Abandoned
- 1999-10-27 HK HK02106802.3A patent/HK1046500A1/zh unknown
- 1999-10-27 ES ES99970920T patent/ES2224751T3/es not_active Expired - Lifetime
- 1999-10-27 EP EP99970920A patent/EP1124556B1/en not_active Expired - Lifetime
- 1999-10-27 WO PCT/US1999/025040 patent/WO2000024400A1/en not_active Ceased
- 1999-10-27 DE DE69918322T patent/DE69918322T2/de not_active Expired - Fee Related
- 1999-10-27 PT PT99970920T patent/PT1124556E/pt unknown
- 1999-10-27 CA CA002348281A patent/CA2348281A1/en not_active Abandoned
- 1999-10-27 HK HK02100988.2A patent/HK1040908B/en not_active IP Right Cessation
- 1999-10-27 DK DK99970920T patent/DK1124556T3/da active
- 1999-10-27 AT AT99970920T patent/ATE269705T1/de not_active IP Right Cessation
- 1999-10-27 GB GB0111739A patent/GB2367748A/en not_active Withdrawn
- 1999-10-27 IL IL14280399A patent/IL142803A0/xx active IP Right Grant
- 1999-10-27 BR BR9914899-4A patent/BR9914899A/pt not_active Application Discontinuation
- 1999-10-27 NZ NZ511744A patent/NZ511744A/en unknown
- 1999-10-27 JP JP2000578009A patent/JP2003522112A/ja active Pending
-
2001
- 2001-04-25 ZA ZA200103376A patent/ZA200103376B/en unknown
- 2001-04-25 IL IL142803A patent/IL142803A/en not_active IP Right Cessation
-
2007
- 2007-05-23 JP JP2007136619A patent/JP2007211028A/ja not_active Withdrawn
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