DK1124556T3 - Anvendelse af optisk rent (R)-tofisopam til behandling og forebyggelse af angstsygdomme - Google Patents
Anvendelse af optisk rent (R)-tofisopam til behandling og forebyggelse af angstsygdommeInfo
- Publication number
- DK1124556T3 DK1124556T3 DK99970920T DK99970920T DK1124556T3 DK 1124556 T3 DK1124556 T3 DK 1124556T3 DK 99970920 T DK99970920 T DK 99970920T DK 99970920 T DK99970920 T DK 99970920T DK 1124556 T3 DK1124556 T3 DK 1124556T3
- Authority
- DK
- Denmark
- Prior art keywords
- prevention
- treatment
- tophisopam
- anxiety disorders
- optically pure
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10580398P | 1998-10-27 | 1998-10-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1124556T3 true DK1124556T3 (da) | 2004-10-11 |
Family
ID=22307874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99970920T DK1124556T3 (da) | 1998-10-27 | 1999-10-27 | Anvendelse af optisk rent (R)-tofisopam til behandling og forebyggelse af angstsygdomme |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1124556B1 (da) |
JP (2) | JP2003522112A (da) |
AT (1) | ATE269705T1 (da) |
AU (1) | AU1451900A (da) |
BR (1) | BR9914899A (da) |
CA (1) | CA2348281A1 (da) |
DE (1) | DE69918322T2 (da) |
DK (1) | DK1124556T3 (da) |
ES (1) | ES2224751T3 (da) |
GB (1) | GB2367748A (da) |
HK (2) | HK1040908B (da) |
IL (2) | IL142803A0 (da) |
NZ (1) | NZ511744A (da) |
PT (1) | PT1124556E (da) |
WO (1) | WO2000024400A1 (da) |
ZA (1) | ZA200103376B (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6649607B2 (en) * | 2001-05-18 | 2003-11-18 | Vela Pharmaceuticals, Inc. | Compositions and methods for treating or preventing convulsions or seizures |
EP1499309A4 (en) * | 2002-04-24 | 2008-05-28 | Cypress Bioscience Inc | PREVENTION AND TREATMENT OF FUNCTIONAL SOMATIC DISEASES, INCLUDING STRESS-BASED DISEASES |
US6638928B1 (en) * | 2002-12-03 | 2003-10-28 | Vela Pharmaceuticals, Inc. | Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines |
JP2006514084A (ja) * | 2002-12-03 | 2006-04-27 | ヴェラ ファーマスーティカルズ インコーポレイテッド | 1−(3−ヒドロキシ−4−メトキシフェニル)−4−メチル−5−エチル−7,8−ジメトキシ−5h−2,3−ベンゾジアゼピンの製薬組成物及びその用途 |
US6864251B2 (en) | 2002-12-03 | 2005-03-08 | Vela Pharmaceuticals, Inc. | Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines |
US7022700B2 (en) | 2002-12-03 | 2006-04-04 | Vela Pharmaceuticals, Inc. | Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines |
MXPA05005895A (es) | 2002-12-03 | 2006-02-08 | Vela Pharmaceuticals Inc | Composicion farmaceutica de 1-(3, 4-dimetoxifenil)-4 -metil-5-etil -7-metoxi-8 -hidroxi- 5h-2, 3-benzodiacepina y usos de la misma. |
JP4611308B2 (ja) * | 2003-05-16 | 2011-01-12 | ヴェラ アクイジション コーポレイション | 鏡像的に純粋な(r)2,3−ベンゾジアゼピンを使用する胃腸の機能不全及び関連するストレスの治療 |
CA2548038A1 (en) * | 2003-12-03 | 2005-06-23 | Vela Pharmaceuticals, Inc. | Treatment of inflammatory disorders of the epithelium with low dose 2,3-benzodiazepines |
FR2870539B1 (fr) * | 2004-05-19 | 2006-08-04 | Greenpharma Sa Sa | Nouvelles methodes et medicaments |
US7541355B2 (en) | 2005-05-23 | 2009-06-02 | Vela Acquisition Corporation | Conversion process for 2,3-benzodiazepine enantiomers |
CN102836162A (zh) * | 2012-04-10 | 2012-12-26 | 珠海亿邦制药股份有限公司 | 一种以托非索泮为活性成分的口服固体制剂及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK118660B (da) * | 1966-12-09 | 1970-09-21 | Egyt Gyogyszervegyeszeti Gyar | Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid. |
ZA712798B (en) * | 1970-11-06 | 1972-02-23 | Egyt Gyogyszervegyeszeti Gyar | New,pharmaceutically active 2,3-diazabicyclo(5.4.0)undecapentaene derivative and process for preparing same |
HU178516B (en) * | 1978-05-05 | 1982-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing enanthiomeres of 1-bracket-3,4-dimethoxy-phenyl-bracket closed-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine and pharmacologically acceptable soles of the /-/-enanthiomere |
HU209530B (en) * | 1988-08-31 | 1994-07-28 | Magnezitipari Muevek Rt | Process for manufacturing of cromit-like, fire resistant materials |
-
1999
- 1999-10-27 JP JP2000578009A patent/JP2003522112A/ja active Pending
- 1999-10-27 BR BR9914899-4A patent/BR9914899A/pt not_active Application Discontinuation
- 1999-10-27 IL IL14280399A patent/IL142803A0/xx active IP Right Grant
- 1999-10-27 AU AU14519/00A patent/AU1451900A/en not_active Abandoned
- 1999-10-27 NZ NZ511744A patent/NZ511744A/en unknown
- 1999-10-27 CA CA002348281A patent/CA2348281A1/en not_active Abandoned
- 1999-10-27 DE DE69918322T patent/DE69918322T2/de not_active Expired - Fee Related
- 1999-10-27 AT AT99970920T patent/ATE269705T1/de not_active IP Right Cessation
- 1999-10-27 WO PCT/US1999/025040 patent/WO2000024400A1/en active IP Right Grant
- 1999-10-27 GB GB0111739A patent/GB2367748A/en not_active Withdrawn
- 1999-10-27 EP EP99970920A patent/EP1124556B1/en not_active Expired - Lifetime
- 1999-10-27 ES ES99970920T patent/ES2224751T3/es not_active Expired - Lifetime
- 1999-10-27 PT PT99970920T patent/PT1124556E/pt unknown
- 1999-10-27 DK DK99970920T patent/DK1124556T3/da active
-
2001
- 2001-04-25 ZA ZA200103376A patent/ZA200103376B/en unknown
- 2001-04-25 IL IL142803A patent/IL142803A/en not_active IP Right Cessation
-
2002
- 2002-02-07 HK HK02100988.2A patent/HK1040908B/zh not_active IP Right Cessation
- 2002-09-17 HK HK02106802.3A patent/HK1046500A1/zh unknown
-
2007
- 2007-05-23 JP JP2007136619A patent/JP2007211028A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2003522112A (ja) | 2003-07-22 |
GB2367748A8 (en) | 2002-12-19 |
CA2348281A1 (en) | 2000-05-04 |
GB2367748A (en) | 2002-04-17 |
BR9914899A (pt) | 2001-07-17 |
ES2224751T3 (es) | 2005-03-01 |
DE69918322D1 (de) | 2004-07-29 |
ZA200103376B (en) | 2003-09-09 |
HK1040908B (zh) | 2005-04-22 |
EP1124556A1 (en) | 2001-08-22 |
IL142803A0 (en) | 2002-03-10 |
GB0111739D0 (en) | 2001-07-04 |
DE69918322T2 (de) | 2005-09-15 |
ATE269705T1 (de) | 2004-07-15 |
IL142803A (en) | 2006-10-05 |
AU1451900A (en) | 2000-05-15 |
HK1040908A1 (en) | 2002-06-28 |
HK1046500A1 (zh) | 2003-01-17 |
WO2000024400A1 (en) | 2000-05-04 |
EP1124556B1 (en) | 2004-06-23 |
PT1124556E (pt) | 2004-10-29 |
JP2007211028A (ja) | 2007-08-23 |
NZ511744A (en) | 2004-04-30 |
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