DK1124556T3 - Anvendelse af optisk rent (R)-tofisopam til behandling og forebyggelse af angstsygdomme - Google Patents

Anvendelse af optisk rent (R)-tofisopam til behandling og forebyggelse af angstsygdomme

Info

Publication number
DK1124556T3
DK1124556T3 DK99970920T DK99970920T DK1124556T3 DK 1124556 T3 DK1124556 T3 DK 1124556T3 DK 99970920 T DK99970920 T DK 99970920T DK 99970920 T DK99970920 T DK 99970920T DK 1124556 T3 DK1124556 T3 DK 1124556T3
Authority
DK
Denmark
Prior art keywords
prevention
treatment
tophisopam
anxiety disorders
optically pure
Prior art date
Application number
DK99970920T
Other languages
English (en)
Inventor
Donald W Landry
Donald F Klein
Original Assignee
Vela Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vela Pharmaceuticals Inc filed Critical Vela Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1124556T3 publication Critical patent/DK1124556T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
DK99970920T 1998-10-27 1999-10-27 Anvendelse af optisk rent (R)-tofisopam til behandling og forebyggelse af angstsygdomme DK1124556T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10580398P 1998-10-27 1998-10-27

Publications (1)

Publication Number Publication Date
DK1124556T3 true DK1124556T3 (da) 2004-10-11

Family

ID=22307874

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99970920T DK1124556T3 (da) 1998-10-27 1999-10-27 Anvendelse af optisk rent (R)-tofisopam til behandling og forebyggelse af angstsygdomme

Country Status (16)

Country Link
EP (1) EP1124556B1 (da)
JP (2) JP2003522112A (da)
AT (1) ATE269705T1 (da)
AU (1) AU1451900A (da)
BR (1) BR9914899A (da)
CA (1) CA2348281A1 (da)
DE (1) DE69918322T2 (da)
DK (1) DK1124556T3 (da)
ES (1) ES2224751T3 (da)
GB (1) GB2367748A (da)
HK (2) HK1040908B (da)
IL (2) IL142803A0 (da)
NZ (1) NZ511744A (da)
PT (1) PT1124556E (da)
WO (1) WO2000024400A1 (da)
ZA (1) ZA200103376B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
EP1499309A4 (en) * 2002-04-24 2008-05-28 Cypress Bioscience Inc PREVENTION AND TREATMENT OF FUNCTIONAL SOMATIC DISEASES, INCLUDING STRESS-BASED DISEASES
US6638928B1 (en) * 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
JP2006514084A (ja) * 2002-12-03 2006-04-27 ヴェラ ファーマスーティカルズ インコーポレイテッド 1−(3−ヒドロキシ−4−メトキシフェニル)−4−メチル−5−エチル−7,8−ジメトキシ−5h−2,3−ベンゾジアゼピンの製薬組成物及びその用途
US6864251B2 (en) 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US7022700B2 (en) 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
MXPA05005895A (es) 2002-12-03 2006-02-08 Vela Pharmaceuticals Inc Composicion farmaceutica de 1-(3, 4-dimetoxifenil)-4 -metil-5-etil -7-metoxi-8 -hidroxi- 5h-2, 3-benzodiacepina y usos de la misma.
JP4611308B2 (ja) * 2003-05-16 2011-01-12 ヴェラ アクイジション コーポレイション 鏡像的に純粋な(r)2,3−ベンゾジアゼピンを使用する胃腸の機能不全及び関連するストレスの治療
CA2548038A1 (en) * 2003-12-03 2005-06-23 Vela Pharmaceuticals, Inc. Treatment of inflammatory disorders of the epithelium with low dose 2,3-benzodiazepines
FR2870539B1 (fr) * 2004-05-19 2006-08-04 Greenpharma Sa Sa Nouvelles methodes et medicaments
US7541355B2 (en) 2005-05-23 2009-06-02 Vela Acquisition Corporation Conversion process for 2,3-benzodiazepine enantiomers
CN102836162A (zh) * 2012-04-10 2012-12-26 珠海亿邦制药股份有限公司 一种以托非索泮为活性成分的口服固体制剂及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK118660B (da) * 1966-12-09 1970-09-21 Egyt Gyogyszervegyeszeti Gyar Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid.
ZA712798B (en) * 1970-11-06 1972-02-23 Egyt Gyogyszervegyeszeti Gyar New,pharmaceutically active 2,3-diazabicyclo(5.4.0)undecapentaene derivative and process for preparing same
HU178516B (en) * 1978-05-05 1982-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing enanthiomeres of 1-bracket-3,4-dimethoxy-phenyl-bracket closed-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine and pharmacologically acceptable soles of the /-/-enanthiomere
HU209530B (en) * 1988-08-31 1994-07-28 Magnezitipari Muevek Rt Process for manufacturing of cromit-like, fire resistant materials

Also Published As

Publication number Publication date
JP2003522112A (ja) 2003-07-22
GB2367748A8 (en) 2002-12-19
CA2348281A1 (en) 2000-05-04
GB2367748A (en) 2002-04-17
BR9914899A (pt) 2001-07-17
ES2224751T3 (es) 2005-03-01
DE69918322D1 (de) 2004-07-29
ZA200103376B (en) 2003-09-09
HK1040908B (zh) 2005-04-22
EP1124556A1 (en) 2001-08-22
IL142803A0 (en) 2002-03-10
GB0111739D0 (en) 2001-07-04
DE69918322T2 (de) 2005-09-15
ATE269705T1 (de) 2004-07-15
IL142803A (en) 2006-10-05
AU1451900A (en) 2000-05-15
HK1040908A1 (en) 2002-06-28
HK1046500A1 (zh) 2003-01-17
WO2000024400A1 (en) 2000-05-04
EP1124556B1 (en) 2004-06-23
PT1124556E (pt) 2004-10-29
JP2007211028A (ja) 2007-08-23
NZ511744A (en) 2004-04-30

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