JP2003519481A5 - - Google Patents
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- JP2003519481A5 JP2003519481A5 JP2001551104A JP2001551104A JP2003519481A5 JP 2003519481 A5 JP2003519481 A5 JP 2003519481A5 JP 2001551104 A JP2001551104 A JP 2001551104A JP 2001551104 A JP2001551104 A JP 2001551104A JP 2003519481 A5 JP2003519481 A5 JP 2003519481A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- ngr
- amino acids
- seq
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17570700P | 2000-01-12 | 2000-01-12 | |
| US60/175,707 | 2000-01-12 | ||
| US20736600P | 2000-05-26 | 2000-05-26 | |
| US60/207,366 | 2000-05-26 | ||
| US23637800P | 2000-09-29 | 2000-09-29 | |
| US60/236,378 | 2000-09-29 | ||
| PCT/US2001/001041 WO2001051520A2 (en) | 2000-01-12 | 2001-01-12 | Nogo receptor-mediated blockade of axonal growth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003519481A JP2003519481A (ja) | 2003-06-24 |
| JP2003519481A5 true JP2003519481A5 (enExample) | 2006-05-11 |
| JP4763207B2 JP4763207B2 (ja) | 2011-08-31 |
Family
ID=27390581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001551104A Expired - Fee Related JP4763207B2 (ja) | 2000-01-12 | 2001-01-12 | 軸索成長のnogoレセプター媒介妨害 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20020012965A1 (enExample) |
| EP (2) | EP1248803B1 (enExample) |
| JP (1) | JP4763207B2 (enExample) |
| KR (1) | KR100828058B1 (enExample) |
| CN (1) | CN100354307C (enExample) |
| AT (1) | ATE466882T1 (enExample) |
| AU (1) | AU784349C (enExample) |
| BG (1) | BG106907A (enExample) |
| BR (1) | BR0107613A (enExample) |
| CA (1) | CA2397199C (enExample) |
| CZ (1) | CZ20022438A3 (enExample) |
| DE (1) | DE60142023D1 (enExample) |
| EA (1) | EA008480B1 (enExample) |
| EE (1) | EE200200386A (enExample) |
| ES (1) | ES2341842T3 (enExample) |
| GE (1) | GEP20063830B (enExample) |
| HK (1) | HK1051543A1 (enExample) |
| HU (1) | HUP0203863A3 (enExample) |
| IL (2) | IL150566A0 (enExample) |
| IS (1) | IS6455A (enExample) |
| MX (1) | MXPA02006885A (enExample) |
| NO (1) | NO20023387L (enExample) |
| NZ (2) | NZ541694A (enExample) |
| PL (1) | PL356887A1 (enExample) |
| SK (1) | SK9992002A3 (enExample) |
| WO (1) | WO2001051520A2 (enExample) |
| YU (1) | YU53502A (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7371836B2 (en) | 1998-03-27 | 2008-05-13 | Genentech, Inc. | PRO526 nucleic acids |
| US7723488B2 (en) | 1998-03-27 | 2010-05-25 | Genentech, Inc. | Monoclonal antibodies to secreted and transmembrane polypeptides |
| US20020072493A1 (en) * | 1998-05-19 | 2002-06-13 | Yeda Research And Development Co. Ltd. | Activated T cells, nervous system-specific antigens and their uses |
| CA2331154A1 (en) | 1998-06-16 | 1999-12-23 | Human Genome Sciences, Inc. | Polypeptides having sequence identity with acid labile subunit of insulin-like growth factor |
| US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US7119165B2 (en) * | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| HUP0203863A3 (en) * | 2000-01-12 | 2008-03-28 | Univ Yale | Nogo receptor-mediated blockade of axonal growth |
| ES2341608T3 (es) | 2000-10-06 | 2010-06-23 | Yale University | Homologos del receptor de nogo. |
| GB0101312D0 (en) * | 2001-01-18 | 2001-02-28 | Glaxo Group Ltd | Assay |
| GB0101313D0 (en) * | 2001-01-18 | 2001-02-28 | Glaxo Group Ltd | Assay |
| EP1386004A4 (en) * | 2001-04-05 | 2005-02-16 | Ribozyme Pharm Inc | MODULATION OF GENE EXPRESSION ASSOCIATED WITH INFLAMMATORY PROLIFERATION AND GROWTH OF NEURITIES BY METHODS INVOLVING NUCLEIC ACID |
| EP1423427A2 (en) * | 2001-08-27 | 2004-06-02 | Novartis AG | Nogo receptor homologues and their use |
| US7309485B2 (en) * | 2001-12-03 | 2007-12-18 | Children's Medical Center Corporation | Reducing myelin-mediated inhibition of axon regeneration |
| FR2841261B1 (fr) * | 2002-06-25 | 2004-08-27 | Univ Pasteur | Compositions et methodes pour detecter les pathologies affectant la transmission neuromusculaire |
| EP1534736B1 (en) * | 2002-08-10 | 2010-06-02 | Yale University | Nogo receptor antagonists |
| ATE469913T1 (de) * | 2002-08-10 | 2010-06-15 | Univ Yale | Antagonisten des nogo-rezeptors |
| GB0228832D0 (en) | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
| CN1745094A (zh) | 2002-12-06 | 2006-03-08 | 新加坡综合医院有限公司 | 肽,其抗体,以及它们在中枢神经系统损伤的治疗中的用途 |
| US7842666B2 (en) * | 2002-12-20 | 2010-11-30 | Research Foundation Of City University Of New York | Inhibitors of myelin-associated glycoprotein (MAG) activity for regulating neural growth and regeneration |
| PL1606409T3 (pl) | 2003-03-19 | 2011-02-28 | Biogen Ma Inc | Białko wiążące receptor Nogo |
| US7541335B2 (en) * | 2003-04-04 | 2009-06-02 | University Of Rochester | Nogo-receptors and methods of use |
| CN1832752A (zh) * | 2003-04-16 | 2006-09-13 | 耶鲁大学 | 治疗淀粉样蛋白斑相关性病症的nogo-受体拮抗剂 |
| JP2007537985A (ja) * | 2003-05-15 | 2007-12-27 | ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニバーシティー | 免疫調節ペプチド |
| US7959914B2 (en) | 2003-05-16 | 2011-06-14 | Acorda Therapeutics, Inc. | Methods of reducing extravasation of inflammatory cells |
| EP3211084B1 (en) * | 2003-05-16 | 2019-03-27 | Acorda Therapeutics, Inc. | Proteoglycan degrading mutants for treatment of cns |
| GB0321997D0 (en) * | 2003-09-19 | 2003-10-22 | Novartis Ag | Organic compound |
| US8912144B2 (en) * | 2003-12-16 | 2014-12-16 | Children's Medical Center Corporation | Method for treating stroke via administration of NEP1-40 and inosine |
| CA2549000A1 (en) * | 2003-12-16 | 2005-06-30 | Children's Medical Center Corporation | Method for treating neurological disorders |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| EP1789070B1 (en) | 2004-08-03 | 2012-10-24 | Biogen Idec MA Inc. | Taj in neuronal function |
| CN101035803A (zh) * | 2004-10-01 | 2007-09-12 | 耶鲁大学 | Nogo-a多肽片段、变异nogo受体-1多肽、及其应用 |
| US20090137484A1 (en) * | 2004-12-01 | 2009-05-28 | National University Of Singapore | Neuronal Network-Interacting Peptide |
| EP1904091A4 (en) | 2005-07-07 | 2009-12-23 | Univ Yale | COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH |
| SI1904104T1 (sl) | 2005-07-08 | 2013-12-31 | Biogen Idec Ma Inc. | Protitelesa SP35 in njihova uporaba |
| JP5189985B2 (ja) | 2005-09-26 | 2013-04-24 | アコーダ セラピューティクス、インク. | コンドロイチナーゼabci変異体を用いた組成物およびその使用方法 |
| EP2526968A3 (en) | 2006-01-27 | 2013-05-22 | Biogen Idec MA Inc. | Nogo receptor antagonists |
| WO2007133746A2 (en) * | 2006-05-15 | 2007-11-22 | Biogen Idec Ma Inc. | Use of nogo receptor-1 (ngr1) antagonists for promoting oligodendrocyte survival |
| EP2068866A4 (en) | 2006-07-24 | 2010-04-07 | Biogen Idec Inc | METHODS FOR PROMOTING MYELINIZATION, NEURONAL SURVIVAL AND DIFFERENTIATION OF OLIGODENDROCYTES BY ADMINISTERING SP35 OR TRKA ANTAGONISTS |
| CA2987970A1 (en) * | 2006-11-21 | 2008-05-29 | Abbvie Inc. | Neutralizing monoclonal antibodies against the nogo-66 receptor (ngr) and uses thereof |
| WO2009114197A2 (en) | 2008-03-13 | 2009-09-17 | Yale University | Reactivation of axon growth and recovery in chronic spinal cord injury |
| US20090285803A1 (en) * | 2008-05-13 | 2009-11-19 | Jasvinder Atwal | ANTI-PirB ANTIBODIES |
| EP2315779A2 (en) | 2008-07-09 | 2011-05-04 | Biogen Idec MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| US9796780B2 (en) | 2012-05-14 | 2017-10-24 | Biogen Ma Inc. | LINGO-2 antagonists for treatment of conditions involving motor neurons |
| CN104935294B (zh) * | 2014-03-20 | 2018-07-20 | 晶宏半导体股份有限公司 | 振荡器 |
| WO2016112270A1 (en) | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
| CN105061560B (zh) * | 2015-07-17 | 2018-10-09 | 暨南大学 | 一种Nogo-A受体结合肽及其衍生物与应用 |
| CN113527462B (zh) * | 2020-04-22 | 2023-05-23 | 北京大学 | 一种具有镇痛作用的小分子肽及其特异性抗体 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4736866B1 (en) | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US4839288A (en) | 1986-01-22 | 1989-06-13 | Institut Pasteur | Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes |
| US5466585A (en) | 1986-04-15 | 1995-11-14 | Ciba-Geigy Corporation | Interferon-induced human protein in pure form, monoclonal antibodies thereto, and test kits containing these antibodies |
| US4861719A (en) | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
| AU3069189A (en) | 1988-02-05 | 1989-08-25 | Trustees Of Columbia University In The City Of New York, The | Retroviral packaging cell lines and processes of using same |
| WO1990002806A1 (en) | 1988-09-01 | 1990-03-22 | Whitehead Institute For Biomedical Research | Recombinant retroviruses with amphotropic and ecotropic host ranges |
| US5250414A (en) | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
| CA1341050C (en) | 1988-11-04 | 2000-07-11 | Martin E. Schwab | Neurite growth regulatory factors |
| EP0396719B1 (en) | 1988-11-04 | 1995-07-05 | Erziehungsdirektion Of The Canton Zurich | Neurite growth regulatory factors |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5723719A (en) | 1991-08-08 | 1998-03-03 | Health Research Inc. | Transgenic mouse as model for diseases involving dopaminergic dysfunction |
| DE4126968A1 (de) | 1991-08-14 | 1993-02-18 | Detlev Prof Dr Med Ganten | Transgene ratten, die in ihrem genom mindestens ein menschliches gen enthalten, das an der blutdruckregulation beteiligt ist |
| WO1993006123A1 (en) | 1991-09-20 | 1993-04-01 | Fred Hutchinson Cancer Research Center | Human cyclin e |
| DE69233109T2 (de) | 1992-01-07 | 2004-05-19 | Elan Pharmaceuticals, Inc., San Francisco | Transgene tiermodelle fur alzheimer-krankheit |
| US5733720A (en) | 1992-06-18 | 1998-03-31 | Washington University | Genetically engineered cell lines for detecting infectious herpesvirus and methods therefor |
| US5602307A (en) | 1992-08-12 | 1997-02-11 | Baylor College Of Medicine | Non-human animal having predefined allele of a cellular adhesion gene |
| US5731490A (en) | 1992-09-29 | 1998-03-24 | The Ontario Cancer Institute | Mutant mouse lacking the expression of interferon regulatory factor 1 (IRF-1) |
| WO1994017831A1 (en) | 1993-02-11 | 1994-08-18 | Erziehungsdirektion Of The Canton Zurich | A combination of neurotrophin and antibody directed toward myelin-associated neurite growth inhibitory protein promotes central nervous system regeneration |
| FR2705361B1 (fr) | 1993-05-18 | 1995-08-04 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
| DK75393D0 (da) | 1993-06-24 | 1993-06-24 | Symbicom Ab | Production of protein |
| WO1995011755A1 (en) | 1993-10-28 | 1995-05-04 | Houston Advanced Research Center | Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions |
| CA2184688A1 (en) | 1994-03-09 | 1995-09-14 | Pedro Antonio Prieto | Transgenic animals producing oligosaccharides and glycoconjugates |
| FR2718329B1 (fr) | 1994-03-21 | 2002-09-20 | Rhone Poulenc Rorer Sa | Lapin transgénique sensibilisé aux dyslipoprotéinémies. |
| US5908969A (en) | 1994-05-13 | 1999-06-01 | The Regents Of The University Of California | Method of detecting prions in a sample and transgenic animal used for same |
| WO2000073452A2 (en) * | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US5728915A (en) | 1995-05-08 | 1998-03-17 | Children's Hospital, Inc. | Transgenic mice which express simian SV 40 T-antigen under control of the retinoblastoma gene promoter |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| US5961976A (en) | 1996-06-03 | 1999-10-05 | United Biomedical, Inc. | Antibodies against a host cell antigen complex for pre- and post-exposure protection from infection by HIV |
| US5858708A (en) | 1996-08-12 | 1999-01-12 | Bandman; Olga | Polynucleotides encoding two novel human neuroendocrine-specific proteins |
| NZ522634A (en) * | 1997-12-03 | 2004-02-27 | Genentech Inc | PRO243 encoding a polypeptide with homology to chordin and antibodies and vectors |
| AU762055B2 (en) * | 1998-03-10 | 2003-06-19 | Genentech Inc. | Novel polypeptides and nucleic acids encoding the same |
| ES2312205T3 (es) * | 1998-03-10 | 2009-02-16 | Genentech, Inc. | Nuevo polipeptido y acidos nucleicos que lo codifican. |
| WO1999053945A1 (en) | 1998-04-16 | 1999-10-28 | Samuel David | Neuron growth inhibitory molecules or derivatives thereof used to immunize mammals thereby promoting axon regeneration |
| JP3659405B2 (ja) * | 1998-04-23 | 2005-06-15 | ジェネンテック・インコーポレーテッド | Sh2ドメイン含有ペプチド |
| JP2002513037A (ja) * | 1998-04-24 | 2002-05-08 | ジェネンテック・インコーポレーテッド | Fizzタンパク質 |
| AU761340B2 (en) * | 1998-06-02 | 2003-06-05 | Genentech Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2331154A1 (en) * | 1998-06-16 | 1999-12-23 | Human Genome Sciences, Inc. | Polypeptides having sequence identity with acid labile subunit of insulin-like growth factor |
| SK287323B6 (sk) * | 1998-11-06 | 2010-07-07 | University Of Z�Rich | Nogo proteín, jeho purifikovaný fragment, chimérny proteín a purifikovaná molekula s jeho obsahom, izolovaná nukleová kyselina, vektor s jej obsahom, rekombinantná bunka, spôsob produkcie rekombinantného proteínu a jeho použitie |
| KR100529270B1 (ko) * | 1998-12-01 | 2005-11-21 | 제넨테크, 인크. | 혈관신생 및 심혈관형성의 촉진 또는 억제 |
| IL143031A0 (en) * | 1998-12-22 | 2002-04-21 | Genentech Inc | Methods and compositions for inhibiting neoplastic cell growth |
| KR20010103046A (ko) * | 1999-03-08 | 2001-11-17 | 제넨테크, 인크. | 면역 관련 질환 치료용 조성물 및 치료 방법 |
| EP1263948A2 (en) * | 1999-03-08 | 2002-12-11 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| JP2004507202A (ja) * | 1999-03-31 | 2004-03-11 | キュラジェン コーポレイション | ポリペプチドをコードするオープンリーディングフレームを含む核酸;「orfx」 |
| AU3632600A (en) * | 1999-05-14 | 2000-12-05 | Genentech Inc. | Compositions and methods for the treatment of immune related diseases |
| EP1268506A4 (en) * | 1999-07-30 | 2004-07-28 | Millennium Pharm Inc | SECRET PROTEINS AND THEIR USE |
| HUP0203863A3 (en) * | 2000-01-12 | 2008-03-28 | Univ Yale | Nogo receptor-mediated blockade of axonal growth |
-
2001
- 2001-01-12 HU HU0203863A patent/HUP0203863A3/hu unknown
- 2001-01-12 EP EP01942367A patent/EP1248803B1/en not_active Expired - Lifetime
- 2001-01-12 EA EA200200755A patent/EA008480B1/ru not_active IP Right Cessation
- 2001-01-12 CA CA2397199A patent/CA2397199C/en not_active Expired - Fee Related
- 2001-01-12 DE DE60142023T patent/DE60142023D1/de not_active Expired - Lifetime
- 2001-01-12 MX MXPA02006885A patent/MXPA02006885A/es not_active Application Discontinuation
- 2001-01-12 KR KR1020027008912A patent/KR100828058B1/ko not_active Expired - Fee Related
- 2001-01-12 SK SK999-2002A patent/SK9992002A3/sk unknown
- 2001-01-12 WO PCT/US2001/001041 patent/WO2001051520A2/en not_active Ceased
- 2001-01-12 NZ NZ541694A patent/NZ541694A/en unknown
- 2001-01-12 ES ES01942367T patent/ES2341842T3/es not_active Expired - Lifetime
- 2001-01-12 BR BR0107613-2A patent/BR0107613A/pt not_active IP Right Cessation
- 2001-01-12 EP EP09170776A patent/EP2163561A1/en not_active Withdrawn
- 2001-01-12 AT AT01942367T patent/ATE466882T1/de not_active IP Right Cessation
- 2001-01-12 CN CNB018049400A patent/CN100354307C/zh not_active Expired - Fee Related
- 2001-01-12 HK HK03102060.8A patent/HK1051543A1/zh unknown
- 2001-01-12 AU AU29401/01A patent/AU784349C/en not_active Ceased
- 2001-01-12 EE EEP200200386A patent/EE200200386A/xx unknown
- 2001-01-12 IL IL15056601A patent/IL150566A0/xx active IP Right Grant
- 2001-01-12 GE GE4901A patent/GEP20063830B/en unknown
- 2001-01-12 PL PL01356887A patent/PL356887A1/xx unknown
- 2001-01-12 US US09/758,140 patent/US20020012965A1/en not_active Abandoned
- 2001-01-12 JP JP2001551104A patent/JP4763207B2/ja not_active Expired - Fee Related
- 2001-01-12 CZ CZ20022438A patent/CZ20022438A3/cs unknown
- 2001-01-12 NZ NZ520065A patent/NZ520065A/en unknown
- 2001-01-12 YU YU53502A patent/YU53502A/sh unknown
-
2002
- 2002-07-03 IL IL150566A patent/IL150566A/en not_active IP Right Cessation
- 2002-07-03 IS IS6455A patent/IS6455A/is unknown
- 2002-07-05 BG BG106907A patent/BG106907A/bg unknown
- 2002-07-12 NO NO20023387A patent/NO20023387L/no not_active Application Discontinuation
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