JP2003516526A5 - - Google Patents

Download PDF

Info

Publication number
JP2003516526A5
JP2003516526A5 JP2001543157A JP2001543157A JP2003516526A5 JP 2003516526 A5 JP2003516526 A5 JP 2003516526A5 JP 2001543157 A JP2001543157 A JP 2001543157A JP 2001543157 A JP2001543157 A JP 2001543157A JP 2003516526 A5 JP2003516526 A5 JP 2003516526A5
Authority
JP
Japan
Prior art keywords
composition
individual
polynucleotide
kit
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001543157A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003516526A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2000/042307 external-priority patent/WO2001041813A2/en
Publication of JP2003516526A publication Critical patent/JP2003516526A/ja
Publication of JP2003516526A5 publication Critical patent/JP2003516526A5/ja
Pending legal-status Critical Current

Links

JP2001543157A 1999-11-28 2000-11-28 抗体親和性に基づいて狼瘡を処置する方法およびスクリーニング方法ならびにその使用のための組成物 Pending JP2003516526A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16771699P 1999-11-28 1999-11-28
US60/167,716 1999-11-28
PCT/US2000/042307 WO2001041813A2 (en) 1999-11-28 2000-11-28 Methods of treating lupus based on antibody affinity and screening methods and compositions for use thereof

Publications (2)

Publication Number Publication Date
JP2003516526A JP2003516526A (ja) 2003-05-13
JP2003516526A5 true JP2003516526A5 (https=) 2006-03-02

Family

ID=22608518

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001543157A Pending JP2003516526A (ja) 1999-11-28 2000-11-28 抗体親和性に基づいて狼瘡を処置する方法およびスクリーニング方法ならびにその使用のための組成物

Country Status (11)

Country Link
US (2) US7081242B1 (https=)
EP (1) EP1233791A2 (https=)
JP (1) JP2003516526A (https=)
KR (1) KR20020059808A (https=)
CN (2) CN101422614A (https=)
AU (1) AU783282C (https=)
CA (1) CA2391944A1 (https=)
HK (1) HK1045944A1 (https=)
MX (1) MXPA02005236A (https=)
NO (1) NO20022441L (https=)
WO (1) WO2001041813A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858210B1 (en) 1998-06-09 2005-02-22 La Jolla Pharmaceutical Co. Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same
MXPA02005236A (es) 1999-11-28 2004-03-19 Jolla Pharma Metodos de tratamiento de lupus con base en la afinidad de anticuerpos y metodos de separacion por exclusion y composiciones para el uso de los mismos.
US20030114405A1 (en) * 2001-08-13 2003-06-19 Linnik Matthew D. Methods of treating systemic lupus erythematosus in individuals having significantly impaired renal function
WO2004060320A2 (en) * 2002-12-27 2004-07-22 La Jolla Pharmaceutical Company Methods of improving health-related quality of life in individuals with systemic lupus erythematosus
US20040258683A1 (en) * 2003-03-30 2004-12-23 Linnik Matthew D. Methods of treating and monitoring systemic lupus erythematosus in individuals
US20060229270A1 (en) * 2005-03-10 2006-10-12 La Jolla Pharmaceutical Company Methods of treating proteinuria by reducing double-stranded DNA antibodies
WO2009052415A1 (en) * 2007-10-17 2009-04-23 The Regents Of The University Of California Peptide for the induction of immune tolerance as treatment for systemic lupus erythematosus
CN102477079A (zh) * 2010-11-24 2012-05-30 中国人民解放军军事医学科学院基础医学研究所 一种新型多肽在系统性红斑狼疮诊断中的应用
WO2012116210A2 (en) * 2011-02-23 2012-08-30 The Regents Of The University Of California Peptide for the induction of immune tolerance as treatment for systemic lupus erythematosus

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022544A (en) 1983-01-24 2000-02-08 The John Hopkins University Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
US5126131A (en) 1983-01-24 1992-06-30 The Johns Hopkins University Therapeutic suppression of specific immune responses by administration of antigen-competitive conjugates.
US5370871A (en) 1983-01-24 1994-12-06 The Johns Hopkins University Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
US5162515A (en) 1990-01-16 1992-11-10 La Jolla Pharmaceutical Company Conjugates of biologically stable polymers and polynucleotides for treating systemic lupus erythematosus
US5268454A (en) 1991-02-08 1993-12-07 La Jolla Pharmaceutical Company Composition for inducing humoral anergy to an immunogen comprising a t cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic carrier
US5552391A (en) 1990-01-16 1996-09-03 La Jolla Pharmaceutical Company Chemically-defined non-polymeric valency platform molecules and conjugates thereof
US5391785A (en) 1990-01-16 1995-02-21 La Jolla Pharmaceutial Company Intermediates for providing functional groups on the 5' end of oligonucleotides
AU8869291A (en) 1990-10-04 1992-04-28 University Of Virginia Alumni Patents Foundation, The Primate erythrocyte bound monoclonal antibody heteropolymers
JP2899111B2 (ja) 1991-07-15 1999-06-02 ラ ホヤ ファーマシューティカル カンパニー オリゴヌクレオチドの5’末端へ官能基を提供するための修飾された亜リン酸中間体
KR100361933B1 (ko) 1993-09-08 2003-02-14 라 졸라 파마슈티칼 컴파니 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
ES2282988T3 (es) * 1993-09-08 2007-10-16 La Jolla Pharmaceutical Company Moleculas plataforma de valencia no polimericas,.
AU696964B2 (en) 1994-02-28 1998-09-24 University Of Virginia Patent Foundation Antigen-based heteropolymers and method for treating autoimmune diseases using the same
US5874409A (en) 1995-06-07 1999-02-23 La Jolla Pharmaceutical Company APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
US5856464A (en) 1995-06-07 1999-01-05 Lajolla Pharmaceutical Company Selective capping solution phase oligonucleotide synthesis
KR20000016414A (ko) 1996-06-06 2000-03-25 와이즈먼 앤드루 Apl 면역반응성 펩티드, 그것의 콘주게이트 및 apl항체-매개병변의 치료방법
US5817752A (en) 1996-06-06 1998-10-06 La Jolla Pharmaceutical Company Cyclic polypeptides comprising a thioether linkage and methods for their preparation
DE69825576T2 (de) 1997-04-11 2005-08-11 Chiyoda Corp., Yokohama Katalysator für die herstellung von synthesegas und verfahren zur herstellung von kohlenmonoxid
US7794946B1 (en) 1998-02-04 2010-09-14 Life Technologies Corporation Microarray and uses therefor
JP4078032B2 (ja) 1998-03-12 2008-04-23 ネクター セラピューティックス エイエル,コーポレイション 近位の反応性基を持つポリ(エチレングリコール)誘導体
US6858210B1 (en) 1998-06-09 2005-02-22 La Jolla Pharmaceutical Co. Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same
MXPA01002580A (es) 1998-09-10 2002-04-08 Univ Virginia Anticuerpos para c3b(1) para el suministro de agentes de diagnostico y terapeuticos para celulas cancerosas.
US6572856B1 (en) 1998-09-10 2003-06-03 The University Of Virginia Patent Foundation Methods for the prevention and treatment of cancer using anti-C3b(i) antibodies
JP2002531531A (ja) 1998-12-09 2002-09-24 ラ ホヤ ファーマシューティカル カンパニー 循環している抗体を減少させるための方法および処方物
US6399578B1 (en) 1998-12-09 2002-06-04 La Jolla Pharmaceutical Company Conjugates comprising galactose α1,3 galactosyl epitopes and methods of using same
US20010010818A1 (en) 1998-12-09 2001-08-02 Engle Steven B. Methods and formulations for reducing circulating antibodies
US6458953B1 (en) 1998-12-09 2002-10-01 La Jolla Pharmaceutical Company Valency platform molecules comprising carbamate linkages
CN1762990A (zh) 1999-06-08 2006-04-26 拉卓拉药物公司 包含氨基氧基的化合价平台分子
MXPA02005236A (es) 1999-11-28 2004-03-19 Jolla Pharma Metodos de tratamiento de lupus con base en la afinidad de anticuerpos y metodos de separacion por exclusion y composiciones para el uso de los mismos.
AU2593901A (en) 1999-12-23 2001-07-03 Elusys Therapeutics, Inc. Therapeutic use of particles displaying pathogen-specific binding moieties
EP1284752A4 (en) 2000-04-26 2004-08-18 Elusys Therapeutics Inc BISPECIFIC MOLECULES AND USES THEREOF
WO2001093914A2 (en) 2000-06-08 2001-12-13 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
US7405276B2 (en) 2000-11-01 2008-07-29 Elusys Therapeutics, Inc. Method of producing bispecific molecules by protein trans-splicing
JP2004529945A (ja) 2001-05-17 2004-09-30 ラ ホヤ ファーマシューティカル カンパニー Cd21を阻害する薬剤を使用して抗体媒介性病理を処置する方法
US20030114405A1 (en) 2001-08-13 2003-06-19 Linnik Matthew D. Methods of treating systemic lupus erythematosus in individuals having significantly impaired renal function
WO2004060320A2 (en) 2002-12-27 2004-07-22 La Jolla Pharmaceutical Company Methods of improving health-related quality of life in individuals with systemic lupus erythematosus
US20040258683A1 (en) 2003-03-30 2004-12-23 Linnik Matthew D. Methods of treating and monitoring systemic lupus erythematosus in individuals

Similar Documents

Publication Publication Date Title
JP2021531826A5 (https=)
RU2447084C2 (ru) Антитела к gdf8 и их применения
JP2013506428A5 (https=)
JP2020522261A5 (https=)
EP2502999A3 (en) Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
JP2018520668A5 (https=)
JP2005225884A5 (https=)
JP2023078174A5 (https=)
CN107076749B (zh) 转移性结直肠癌抗血管发生治疗相关预测和预后生物标志
JP2019511201A5 (https=)
JP2003516526A5 (https=)
JP2019523651A5 (https=)
JP2021522812A5 (https=)
JP2004504808A5 (https=)
JP2019502656A (ja) 改善された血清アルブミン結合性免疫グロブリン可変ドメイン
JP2020530285A5 (https=)
WO2005044859A3 (en) Cd20 antibodies with increased fc receptor binding affinity and effector function
JP2021500916A5 (https=)
JP2015527365A5 (https=)
JP2020516603A5 (https=)
Kroenke et al. Immunogenicity Risk Assessment for Multi-specific Therapeutics: Immunogenicity Risk Assessment for Multi-specific Therapeutics
JP2006526639A5 (https=)
JP2014518377A5 (https=)
RU2014114015A (ru) Способы лечения воспалительных расстройств с использованием антител против m-csf
JPWO2020040245A5 (https=)