JPWO2020040245A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020040245A5 JPWO2020040245A5 JP2020538461A JP2020538461A JPWO2020040245A5 JP WO2020040245 A5 JPWO2020040245 A5 JP WO2020040245A5 JP 2020538461 A JP2020538461 A JP 2020538461A JP 2020538461 A JP2020538461 A JP 2020538461A JP WO2020040245 A5 JPWO2020040245 A5 JP WO2020040245A5
- Authority
- JP
- Japan
- Prior art keywords
- log2
- expression level
- gene
- htrop2
- mrna level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018156449 | 2018-08-23 | ||
| JP2018156449 | 2018-08-23 | ||
| PCT/JP2019/032773 WO2020040245A1 (ja) | 2018-08-23 | 2019-08-22 | 抗体薬物複合体の感受性マーカー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020040245A1 JPWO2020040245A1 (ja) | 2021-09-02 |
| JPWO2020040245A5 true JPWO2020040245A5 (https=) | 2022-08-29 |
| JP7481255B2 JP7481255B2 (ja) | 2024-05-10 |
Family
ID=69591927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020538461A Active JP7481255B2 (ja) | 2018-08-23 | 2019-08-22 | 抗体薬物複合体の感受性マーカー |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12312641B2 (https=) |
| EP (1) | EP3842546A4 (https=) |
| JP (1) | JP7481255B2 (https=) |
| CN (1) | CN112739826A (https=) |
| TW (1) | TW202016317A (https=) |
| WO (1) | WO2020040245A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL288485B2 (en) * | 2019-05-29 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-TROP2 antibody conjugates - a drug for use in cancer treatment |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
| TW202320858A (zh) | 2021-07-19 | 2023-06-01 | 美商薩諾管理公司 | 免疫接合物及方法 |
| EP4514391A1 (en) | 2022-04-27 | 2025-03-05 | Daiichi Sankyo Company, Limited | Combination of antibody-drug conjugate with ezh1 and/or ezh2 inhibitor |
| CN119490585B (zh) * | 2024-12-03 | 2025-09-23 | 河南农业大学 | 一种抗猪源slfn11蛋白单克隆抗体及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| DK1071700T3 (da) | 1998-04-20 | 2010-06-07 | Glycart Biotechnology Ag | Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet |
| CA2704600C (en) | 1999-04-09 | 2016-10-25 | Kyowa Kirin Co., Ltd. | A method for producing antibodies with increased adcc activity |
| CN100340575C (zh) | 1999-06-25 | 2007-10-03 | 杰南技术公司 | 人源化抗ErbB2抗体及其在制备药物中的应用 |
| CA2953239A1 (en) | 2000-10-06 | 2002-04-18 | Kyowa Hakko Kirin Co., Ltd. | Antibody composition-producing cell |
| CA2478047C (en) | 2002-03-01 | 2014-01-21 | Immunomedics, Inc. | Rs7 antibodies |
| CA2542656A1 (en) | 2003-10-16 | 2005-05-06 | Genomic Health, Inc. | Qrt-pcr assay system for gene expression profiling |
| AR056857A1 (es) | 2005-12-30 | 2007-10-24 | U3 Pharma Ag | Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos |
| US20080131428A1 (en) | 2006-02-24 | 2008-06-05 | Arius Research, Inc. | Cytotoxicity mediation of cells evidencing surface expression of TROP-2 |
| KR101598229B1 (ko) | 2007-02-16 | 2016-02-26 | 메리맥 파마슈티컬즈, 인크. | Ｅｒｂｂ3에 대한 항체 및 이의 용도 |
| ES3000111T3 (en) | 2009-02-13 | 2025-02-27 | Immunomedics Inc | Intermediates for preparing conjugates with an intracellularly-cleavable linkage |
| ES2978177T3 (es) | 2009-12-02 | 2024-09-06 | Immunomedics Inc | Combinación de radio inmunoterapia y conjugados anticuerpo-fármaco para mejorar la terapia contra el cáncer |
| EA201500220A1 (ru) | 2010-05-17 | 2015-10-30 | Ливтех, Инк. | Антитело против trop-2 человека, обладающее противоопухолевой активностью in vivo |
| WO2011155579A1 (ja) | 2010-06-10 | 2011-12-15 | 北海道公立大学法人札幌医科大学 | 抗Ｔｒｏｐ－２抗体 |
| TWI495644B (zh) | 2011-11-11 | 2015-08-11 | Rinat Neuroscience Corp | 營養層細胞表面抗原（Ｔｒｏｐ－２）之專一性抗體類及彼等之用途 |
| US9427464B2 (en) | 2011-11-22 | 2016-08-30 | Chiome Bioscience Inc. | Anti-human TROP-2 antibody having an antitumor activity in vivo |
| ES2773710T3 (es) | 2012-10-11 | 2020-07-14 | Daiichi Sankyo Co Ltd | Enlazadores para conjugados de anticuerpo - fármaco |
| WO2014061277A1 (ja) | 2012-10-19 | 2014-04-24 | 第一三共株式会社 | 親水性構造を含むリンカーで結合させた抗体－薬物コンジュゲート |
| AU2014371934B2 (en) | 2013-12-25 | 2020-01-23 | Daiichi Sankyo Company, Limited | Anti-TROP2 antibody-drug conjugate |
| IL310627B2 (en) | 2014-01-31 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof |
| JP2017114763A (ja) | 2014-03-26 | 2017-06-29 | 第一三共株式会社 | 抗ｃｄ９８抗体−薬物コンジュゲート |
| KR102445502B1 (ko) | 2014-04-10 | 2022-09-21 | 다이이찌 산쿄 가부시키가이샤 | 항her3 항체-약물 콘주게이트 |
| EP3130608B1 (en) | 2014-04-10 | 2019-09-04 | Daiichi Sankyo Co., Ltd. | (anti-her2 antibody)-drug conjugate |
| CN116059395A (zh) | 2015-06-29 | 2023-05-05 | 第一三共株式会社 | 用于选择性制造抗体-药物缀合物的方法 |
| JP6679762B2 (ja) | 2017-01-17 | 2020-04-15 | 第一三共株式会社 | 抗ｇｐｒ２０抗体及び抗ｇｐｒ２０抗体−薬物コンジュゲート |
| TW202532104A (zh) | 2017-05-15 | 2025-08-16 | 日商第一三共股份有限公司 | 抗體－藥物結合物及其用途 |
-
2019
- 2019-08-22 CN CN201980055378.2A patent/CN112739826A/zh active Pending
- 2019-08-22 EP EP19850901.0A patent/EP3842546A4/en active Pending
- 2019-08-22 US US17/269,615 patent/US12312641B2/en active Active
- 2019-08-22 WO PCT/JP2019/032773 patent/WO2020040245A1/ja not_active Ceased
- 2019-08-22 JP JP2020538461A patent/JP7481255B2/ja active Active
- 2019-08-22 TW TW108130044A patent/TW202016317A/zh unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2020040245A5 (https=) | ||
| JP7458981B2 (ja) | 抗体－薬物コンジュゲートとチューブリン阻害剤の組み合わせ | |
| JP7512202B2 (ja) | ヒト化抗前立腺特異的膜抗原（ｐｓｍａ）抗体薬物複合体 | |
| ES2595091T3 (es) | Composiciones farmacéuticas con resistencia a CEA soluble | |
| JPWO2020122034A5 (https=) | ||
| JP2022512132A (ja) | 抗クローディン抗体及びそれらの使用 | |
| WO2021142039A1 (en) | Anti-psma antibodies, antibody drug conjugates, and methods of use thereof | |
| CN111587124A (zh) | Ror1抗体免疫缀合物 | |
| JP2018525354A5 (https=) | ||
| JP2020502271A5 (https=) | ||
| KR20170008202A (ko) | 흑색종에 사용하기 위한 항-ｄｌｌ3 항체 및 약물 접합체 | |
| KR20210151945A (ko) | 대식세포 활성을 조정하기 위한 방법 | |
| JP2019516705A (ja) | 神経内分泌移行のリスクのある腫瘍を治療するための抗ｄｌｌ３薬物コンジュゲート | |
| JP2017517507A5 (https=) | ||
| JP2017526339A5 (https=) | ||
| WO2018038684A1 (en) | Macrophage stimulating protein receptor (or ron - recepteur d' origine nantais) antibodies and uses thereof | |
| JP2024544520A5 (https=) | ||
| JP2025123308A (ja) | ＴＲＢＣβ抗体コンジュゲート | |
| CN118076387A (zh) | 靶向表达cdh17的肿瘤的多特异性抗体及其制备和使用方法 | |
| JP2014515600A5 (https=) | ||
| TW201905000A (zh) | 含有抗globo h抗體之抗體－藥物共軛物及其用途 | |
| JP2026501556A (ja) | 抗体薬物複合体 | |
| US20180171027A1 (en) | Biomarkers Related to Treatment of Cancer with HER3 and EGFR Inhibitors | |
| CN115485298A (zh) | 用于治疗癌症的egfr抑制剂和ror1抑制剂的组合 | |
| JP2023548590A (ja) | 小細胞肺がんの分類と治療のための方法およびシステム |