JP2003513045A - 便秘及び過敏性大腸症候群を治療・処置するための組成物 - Google Patents

便秘及び過敏性大腸症候群を治療・処置するための組成物

Info

Publication number
JP2003513045A
JP2003513045A JP2001534385A JP2001534385A JP2003513045A JP 2003513045 A JP2003513045 A JP 2003513045A JP 2001534385 A JP2001534385 A JP 2001534385A JP 2001534385 A JP2001534385 A JP 2001534385A JP 2003513045 A JP2003513045 A JP 2003513045A
Authority
JP
Japan
Prior art keywords
release
opioid antagonist
antagonist
opioid
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001534385A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003513045A5 (enExample
Inventor
ローズ、ジョーン
エバンス、ブライアン、ケネス
Original Assignee
ロデバ・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9925872A external-priority patent/GB9925872D0/en
Priority claimed from GB9928314A external-priority patent/GB9928314D0/en
Application filed by ロデバ・リミテッド filed Critical ロデバ・リミテッド
Publication of JP2003513045A publication Critical patent/JP2003513045A/ja
Publication of JP2003513045A5 publication Critical patent/JP2003513045A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2001534385A 1999-11-01 2000-10-30 便秘及び過敏性大腸症候群を治療・処置するための組成物 Pending JP2003513045A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9925872.5 1999-11-01
GB9925872A GB9925872D0 (en) 1999-11-01 1999-11-01 Composition for relief of constipation
GB9928314.5 1999-11-30
GB9928314A GB9928314D0 (en) 1999-11-30 1999-11-30 Composition for the treatment of irritable bowel syndrome
PCT/GB2000/004167 WO2001032180A2 (en) 1999-11-01 2000-10-30 Composition for treatment of constipation and irritable bowel syndrome

Publications (2)

Publication Number Publication Date
JP2003513045A true JP2003513045A (ja) 2003-04-08
JP2003513045A5 JP2003513045A5 (enExample) 2007-11-01

Family

ID=26316047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001534385A Pending JP2003513045A (ja) 1999-11-01 2000-10-30 便秘及び過敏性大腸症候群を治療・処置するための組成物

Country Status (13)

Country Link
US (1) US6734188B1 (enExample)
EP (1) EP1225897B1 (enExample)
JP (1) JP2003513045A (enExample)
AT (1) ATE275402T1 (enExample)
AU (1) AU776567B2 (enExample)
CA (1) CA2389650C (enExample)
CZ (1) CZ299726B6 (enExample)
DE (1) DE60013630T2 (enExample)
DK (1) DK1225897T3 (enExample)
ES (1) ES2226933T3 (enExample)
IL (2) IL149378A0 (enExample)
PT (1) PT1225897E (enExample)
WO (1) WO2001032180A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014129397A (ja) * 2002-04-05 2014-07-10 Euro-Celtique Sa オキシコドン及びナロキソンを含有する医薬製剤
JP2015531770A (ja) * 2012-08-29 2015-11-05 サリックス ファーマシューティカルズ,インコーポレイテッド 緩下剤組成物、ならびに便秘および関連胃腸疾患および症状を処置するための方法

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DK1685839T3 (da) 1997-12-22 2013-06-24 Euro Celtique Sa Farmaceutisk oral doseringsform omfattende en kombination af en opioidagonist og opioidantagonist
PT1225897E (pt) 1999-11-01 2005-01-31 John Rhodes Composicao para o tratamento da obstipacao e do sindroma do intestino irritavel
AU776666B2 (en) 2000-02-08 2004-09-16 Euro-Celtique S.A. Tamper-resistant oral opioid agonist formulations
CN1525851A (zh) 2001-05-11 2004-09-01 ������ҩ�����޹�˾ 抗滥用阿片样物质控释剂型
US7943173B2 (en) 2001-07-18 2011-05-17 Purdue Pharma L.P. Pharmaceutical combinations of oxycodone and naloxone
US20030157168A1 (en) 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
WO2003013525A1 (en) 2001-08-06 2003-02-20 Euro-Celtique S.A. Opioid agonist formulations with releasable and sequestered antagonist
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
DK1551372T3 (en) 2002-09-20 2018-07-23 Alpharma Pharmaceuticals Llc SEQUERATION SUBSTANCES AND RELATED COMPOSITIONS AND PROCEDURES
ATE477268T1 (de) 2003-01-28 2010-08-15 Ironwood Pharmaceuticals Inc Zusammensetzungen zur behandlung von magen-darm- störungen
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
HRP20150037T4 (hr) 2003-04-08 2022-09-02 Progenics Pharmaceuticals, Inc. Farmaceutske formulacije koje sadrže metilnaltrekson
JP2006522817A (ja) * 2003-04-08 2006-10-05 プロジェニックス ファーマシューティカルズ,インコーポレーテッド 過敏性腸症候群を処置するための末梢オピオイドアンタゴニスト、特にメチルナルトレキソンの使用
TWI347201B (en) 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
US8017622B2 (en) * 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
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US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
CN101171010B (zh) 2005-03-07 2014-09-17 芝加哥大学 阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
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US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
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US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
EP2240489A1 (en) 2008-02-06 2010-10-20 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
EP2278966B1 (en) 2008-03-21 2019-10-09 The University of Chicago Treatment with opioid antagonists and mtor inhibitors
KR20110004425A (ko) * 2008-05-07 2011-01-13 넥타르 테라퓨틱스 말초적 작용 오피오이드 길항제의 경구 투여
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
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WO1997028801A1 (en) * 1996-02-09 1997-08-14 Mayo Foundation For Medical Education And Research Colonic delivery of nicotine to treat inflammatory bowel disease
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014129397A (ja) * 2002-04-05 2014-07-10 Euro-Celtique Sa オキシコドン及びナロキソンを含有する医薬製剤
JP2015531770A (ja) * 2012-08-29 2015-11-05 サリックス ファーマシューティカルズ,インコーポレイテッド 緩下剤組成物、ならびに便秘および関連胃腸疾患および症状を処置するための方法

Also Published As

Publication number Publication date
DK1225897T3 (da) 2005-01-10
WO2001032180A3 (en) 2001-09-20
US6734188B1 (en) 2004-05-11
PT1225897E (pt) 2005-01-31
HK1048595A1 (en) 2003-04-11
DE60013630D1 (de) 2004-10-14
IL149378A0 (en) 2002-11-10
EP1225897B1 (en) 2004-09-08
IL149378A (en) 2006-12-31
CZ299726B6 (cs) 2008-11-05
ATE275402T1 (de) 2004-09-15
AU776567B2 (en) 2004-09-16
WO2001032180A2 (en) 2001-05-10
AU1044701A (en) 2001-05-14
DE60013630T2 (de) 2005-09-15
ES2226933T3 (es) 2005-04-01
CA2389650A1 (en) 2001-05-10
EP1225897A2 (en) 2002-07-31
CZ20021536A3 (cs) 2003-02-12
CA2389650C (en) 2008-12-09

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