IT1188550B - Peptide sintetico ad attivita' interleukina 1 umana - Google Patents

Peptide sintetico ad attivita' interleukina 1 umana

Info

Publication number
IT1188550B
IT1188550B IT19338/86A IT1933886A IT1188550B IT 1188550 B IT1188550 B IT 1188550B IT 19338/86 A IT19338/86 A IT 19338/86A IT 1933886 A IT1933886 A IT 1933886A IT 1188550 B IT1188550 B IT 1188550B
Authority
IT
Italy
Prior art keywords
glu
synthetic peptide
interleukina
human activity
gln
Prior art date
Application number
IT19338/86A
Other languages
English (en)
Other versions
IT8619338A0 (it
IT8619338A1 (it
Inventor
Aldo Tagliabue
Guido Antoni
Rivo Presentini
Dian Boraschi
Original Assignee
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo Spa filed Critical Sclavo Spa
Publication of IT8619338A0 publication Critical patent/IT8619338A0/it
Priority to IT19338/86A priority Critical patent/IT1188550B/it
Priority to EP86830299A priority patent/EP0231728B1/en
Priority to DE8686830299T priority patent/DE3679396D1/de
Priority to ES86830299T priority patent/ES2044841T3/es
Priority to AT86830299T priority patent/ATE63749T1/de
Priority to US06/922,066 priority patent/US4774320A/en
Priority to JP61258711A priority patent/JPS62185095A/ja
Publication of IT8619338A1 publication Critical patent/IT8619338A1/it
Application granted granted Critical
Publication of IT1188550B publication Critical patent/IT1188550B/it
Priority to GR91401226T priority patent/GR3002597T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin
IT19338/86A 1986-02-07 1986-02-07 Peptide sintetico ad attivita' interleukina 1 umana IT1188550B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT19338/86A IT1188550B (it) 1986-02-07 1986-02-07 Peptide sintetico ad attivita' interleukina 1 umana
AT86830299T ATE63749T1 (de) 1986-02-07 1986-10-17 Synthetisches peptid mit menschlicher interleukin 1-wirksamkeit.
DE8686830299T DE3679396D1 (de) 1986-02-07 1986-10-17 Synthetisches peptid mit menschlicher interleukin 1-wirksamkeit.
ES86830299T ES2044841T3 (es) 1986-02-07 1986-10-17 Procedimiento de preparacion de peptidos sinteticos con actividad de interleuquin 1 humana.
EP86830299A EP0231728B1 (en) 1986-02-07 1986-10-17 Synthetic peptide with human interleukin 1 activity
US06/922,066 US4774320A (en) 1986-02-07 1986-10-20 Synthetic peptide with human interleukin 1 activity
JP61258711A JPS62185095A (ja) 1986-02-07 1986-10-31 合成ペプチド
GR91401226T GR3002597T3 (en) 1986-02-07 1991-08-22 Synthetic peptide with human interleukin 1 activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19338/86A IT1188550B (it) 1986-02-07 1986-02-07 Peptide sintetico ad attivita' interleukina 1 umana

Publications (3)

Publication Number Publication Date
IT8619338A0 IT8619338A0 (it) 1986-02-07
IT8619338A1 IT8619338A1 (it) 1987-08-07
IT1188550B true IT1188550B (it) 1988-01-14

Family

ID=11156864

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19338/86A IT1188550B (it) 1986-02-07 1986-02-07 Peptide sintetico ad attivita' interleukina 1 umana

Country Status (8)

Country Link
US (1) US4774320A (it)
EP (1) EP0231728B1 (it)
JP (1) JPS62185095A (it)
AT (1) ATE63749T1 (it)
DE (1) DE3679396D1 (it)
ES (1) ES2044841T3 (it)
GR (1) GR3002597T3 (it)
IT (1) IT1188550B (it)

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US5484887A (en) * 1984-06-19 1996-01-16 Immunex Corporation Homogeneous interleukin 1
US4994553A (en) * 1985-10-02 1991-02-19 Merck & Co., Inc. Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US4801686A (en) * 1986-09-04 1989-01-31 Immunex Corporation Purification of recombinant interleukin-1
IT1217314B (it) * 1987-02-20 1990-03-22 Sclavo Spa Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale
US5110600A (en) * 1988-01-25 1992-05-05 The Regents Of The University Of California Method of treating viral infections with amino acid analogs
US5039790A (en) * 1989-01-11 1991-08-13 Monsanto Company Bioactive fragment of interleukin-1-B that has antagonistic activity
US4983402A (en) * 1989-02-24 1991-01-08 Clinical Technologies Associates, Inc. Orally administerable ANF
US4976968A (en) * 1989-02-24 1990-12-11 Clinical Technologies Associates, Inc. Anhydrous delivery systems for pharmacological agents
US4963364A (en) * 1989-04-10 1990-10-16 Fox Sidney W Microencapsulated antitumor agent
WO1991017184A1 (en) * 1990-04-27 1991-11-14 The Upjohn Company Modified interleukin-1 inhibitors
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5443841A (en) * 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5447728A (en) * 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5449691A (en) * 1991-12-31 1995-09-12 Sterling Winthrop Inc. 3,4-disubstituted anilines-immunomodulating agents
US5258407A (en) * 1991-12-31 1993-11-02 Sterling Winthrop Inc. 3,4-disubstituted phenols-immunomodulating agents
US5811127A (en) * 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5792451A (en) * 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5643957A (en) * 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
IL109403A0 (en) * 1993-04-22 1994-07-31 Emisphere Tech Inc Oral drug delivery compositions and methods
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CN1151836C (zh) * 1995-03-31 2004-06-02 艾米斯菲尔技术有限公司 用作传送活性剂的化合物和组合物
US5965121A (en) * 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) * 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5820881A (en) * 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
WO1996034887A2 (en) * 1995-05-05 1996-11-07 Imperial College Of Science, Technology & Medicine Antisense peptides
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US5667806A (en) * 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5824345A (en) * 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
AU7072596A (en) * 1995-09-11 1997-04-01 Emisphere Technologies, Inc. Method for preparing omega-aminoalkanoic acid derivatives from cycloalkanones
SI9720025A (sl) 1996-03-29 1999-08-31 Emishphere Technologies, Inc. Spojine in sestavki za prenos aktivne snovi
WO1997047288A1 (en) 1996-06-14 1997-12-18 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US6103239A (en) * 1996-08-09 2000-08-15 Cel-Sci Corporation Modified HGP-30 heteroconjugates, compositions and methods of use
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5879681A (en) * 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5939381A (en) * 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
ES2226933T3 (es) * 1999-11-01 2005-04-01 John Rhodes Composicion para tratar el estreñimiento y el sindrome del intestino irritable.
CN108314700B (zh) * 2018-02-27 2021-08-03 青岛大学 一种固相合成多肽的方法、合成的磁性纳米探针及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK221681A (da) * 1980-05-22 1981-11-23 Inst Nat Sante Fremgangsmaade til fremstilling af biologisk virksomme og radioimmunologisk anvendelige produkter ud fra serum-thymusfaktoren
JPS5711950A (en) * 1980-06-25 1982-01-21 Kureha Chem Ind Co Ltd Peptide and its synthesis

Also Published As

Publication number Publication date
EP0231728A3 (en) 1989-05-03
IT8619338A0 (it) 1986-02-07
ES2044841T3 (es) 1994-01-16
EP0231728A2 (en) 1987-08-12
DE3679396D1 (de) 1991-06-27
GR3002597T3 (en) 1993-01-25
EP0231728B1 (en) 1991-05-22
JPS62185095A (ja) 1987-08-13
IT8619338A1 (it) 1987-08-07
ATE63749T1 (de) 1991-06-15
US4774320A (en) 1988-09-27

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