DE69128779D1 - Epitheline: neue cystein-reiche, den wachstum modulierende proteine - Google Patents

Epitheline: neue cystein-reiche, den wachstum modulierende proteine

Info

Publication number
DE69128779D1
DE69128779D1 DE69128779T DE69128779T DE69128779D1 DE 69128779 D1 DE69128779 D1 DE 69128779D1 DE 69128779 T DE69128779 T DE 69128779T DE 69128779 T DE69128779 T DE 69128779T DE 69128779 D1 DE69128779 D1 DE 69128779D1
Authority
DE
Germany
Prior art keywords
epithelin
growth
epithelins
purified
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69128779T
Other languages
English (en)
Inventor
Mohammed Shoyab
Gregory Plowman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE69128779D1 publication Critical patent/DE69128779D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69128779T 1990-04-03 1991-04-03 Epitheline: neue cystein-reiche, den wachstum modulierende proteine Expired - Lifetime DE69128779D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50450890A 1990-04-03 1990-04-03
US07/668,648 US5416192A (en) 1990-04-03 1991-03-13 Epithelins: novel cysteine-rich growth modulating proteins
PCT/US1991/002321 WO1991015510A1 (en) 1990-04-03 1991-04-03 Epithelins: novel cysteine - rich growth modulating proteins

Publications (1)

Publication Number Publication Date
DE69128779D1 true DE69128779D1 (de) 1998-02-26

Family

ID=27054846

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69128779T Expired - Lifetime DE69128779D1 (de) 1990-04-03 1991-04-03 Epitheline: neue cystein-reiche, den wachstum modulierende proteine

Country Status (15)

Country Link
US (3) US5416192A (de)
EP (1) EP0527806B1 (de)
CN (1) CN1058782A (de)
AT (1) ATE162549T1 (de)
AU (1) AU639787B2 (de)
CA (1) CA2079218A1 (de)
CS (1) CS91791A3 (de)
DE (1) DE69128779D1 (de)
GR (1) GR3026263T3 (de)
HU (1) HUT63438A (de)
IE (1) IE911117A1 (de)
IL (1) IL97758A0 (de)
NZ (1) NZ237661A (de)
OA (1) OA09711A (de)
WO (1) WO1991015510A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1325792A (en) * 1992-02-03 1993-09-01 Samuel Solomon Granulins from leukocytes
WO2000055319A1 (en) * 1999-03-12 2000-09-21 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
WO2000032778A2 (en) * 1998-12-01 2000-06-08 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
WO2000053751A1 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
US20100111928A1 (en) * 1997-05-23 2010-05-06 A & G Pharmaceutical, Inc. Methods and kits for diagnosis tumorgenicity
US7091047B2 (en) * 1997-05-23 2006-08-15 A&G Pharmaceutical, Inc. Methods and kits for diagnosing tumorigenicity
US6309826B1 (en) * 1997-05-23 2001-10-30 Ginette Serrero 88kDa tumorigenic growth factor and antagonists
US6720159B1 (en) 1997-12-16 2004-04-13 A&G Pharmaceutical, Inc. 88KDA tumorigenic growth factor and antagonists
US8512960B2 (en) * 1997-05-23 2013-08-20 A&G Pharmaceutical, Inc. 88kDa tumorigenic growth factor and antagonists
US6881548B2 (en) * 1997-05-23 2005-04-19 A&G Pharmaceutical, Inc. Methods and kits for diagnosing tumorigenicity and determining resistance to the antineoplastic effects of antiestrogen therapy
US20030215445A1 (en) * 1997-05-23 2003-11-20 Ginette Serrero Methods and compositions for inhibiting the growth of hematopoietic malignant cells
EP1121439B1 (de) * 1998-10-13 2006-07-12 Genentech, Inc. Verfahren und zusammensetzungen zur hemmung von neoplastischem zellwachstums
EP1484338B1 (de) * 1998-12-22 2007-02-07 Genentech, Inc. Verfahren und Zusammensetzung zur Hemmung des neoplastischen Zellwachstums
IL143031A0 (en) * 1998-12-22 2002-04-21 Genentech Inc Methods and compositions for inhibiting neoplastic cell growth
AU3246100A (en) * 1999-06-02 2000-12-28 Genentech Inc. Methods and compositions for inhibiting neoplastic cell growth
EP1867719A3 (de) * 1999-06-02 2008-03-19 Genentech, Inc. Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums
AU2215300A (en) * 1999-06-02 2000-12-28 Genentech Inc. Methods and compositions for inhibiting neoplastic cell growth
DK1185648T3 (da) * 1999-06-02 2007-07-30 Genentech Inc Fremgangsmåder og sammensætninger til inhibition af neoplastisk cellevækst
EP1244784A2 (de) * 2000-01-06 2002-10-02 Genentech, Inc. Verfahren und zusammensetzungen zur hemmung des wachstums von neoplastischen zellen
AU2001241877A1 (en) * 2000-02-28 2001-09-12 The Regents Of The University Of California Methods for detection and treatment of neural cancers
US6872703B2 (en) * 2000-06-07 2005-03-29 Ajinomoto Co., Inc. Insulin receptor-related receptor binding protein
AUPR673001A0 (en) * 2001-07-31 2001-08-23 Prince Henry's Institute Of Medical Research Pregnancy-related enzyme activity
US20030215849A1 (en) * 2002-03-01 2003-11-20 Marcia Belvin PDPK1s as modifiers of the p53 pathway and methods of use
US7411045B2 (en) * 2002-11-19 2008-08-12 A&G Pharmaceutical, Inc. Autocrine growth factor receptor antibodies and methods
JP4488903B2 (ja) * 2003-02-26 2010-06-23 エイアンドジー ファーマスーティカル インコーポレイテッド Ｂ細胞の増殖を増加させる方法
EP1644038A2 (de) * 2003-06-23 2006-04-12 A & G Pharmaceuticals, Inc. Zusammenetzungen und verfahren zur wiederherstellung der emfpindlichkeit von tumorzellen auf eine antitumorale therapie und einleitung von apoptose
WO2005009363A2 (en) * 2003-07-21 2005-02-03 Medimmune, Inc. Treatment of pre-cancerous conditions and prevention of cancer using pcdgf-based therapies
WO2005011590A2 (en) * 2003-08-01 2005-02-10 A & G Pharmaceutical, Inc. Compositions and methods for restoring sensitivity to treatment with her2 antagonists
KR101690249B1 (ko) 2008-09-05 2016-12-27 에이 앤드 지 파마슈티컬즈, 인코포레이티드 암의 진단 방법 및 암 환자의 전반적 생존 및 무질병 생존의 측정 방법
CA2758542A1 (en) 2009-04-17 2010-10-21 New York University Peptides targeting tnf family receptors and antagonizing tnf action, compositions, methods and uses thereof
US9913399B2 (en) 2015-02-09 2018-03-06 Dell Products, Lp System and method for wireless rack management controller communication

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590003A (en) * 1984-03-23 1986-05-20 Oncogen Platelet related growth regulator

Also Published As

Publication number Publication date
EP0527806A4 (en) 1993-05-05
CN1058782A (zh) 1992-02-19
AU639787B2 (en) 1993-08-05
AU7744791A (en) 1991-10-30
US5965723A (en) 1999-10-12
CA2079218A1 (en) 1991-10-04
CS91791A3 (en) 1992-06-17
IE911117A1 (en) 1991-10-09
NZ237661A (en) 1993-07-27
EP0527806B1 (de) 1998-01-21
OA09711A (en) 1993-08-30
US5885961A (en) 1999-03-23
IL97758A0 (en) 1992-06-21
GR3026263T3 (en) 1998-05-29
HU9203137D0 (en) 1992-12-28
US5416192A (en) 1995-05-16
WO1991015510A1 (en) 1991-10-17
HUT63438A (en) 1993-08-30
ATE162549T1 (de) 1998-02-15
EP0527806A1 (de) 1993-02-24

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