ATE178651T1 - Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen - Google Patents
Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellenInfo
- Publication number
- ATE178651T1 ATE178651T1 AT93902252T AT93902252T ATE178651T1 AT E178651 T1 ATE178651 T1 AT E178651T1 AT 93902252 T AT93902252 T AT 93902252T AT 93902252 T AT93902252 T AT 93902252T AT E178651 T1 ATE178651 T1 AT E178651T1
- Authority
- AT
- Austria
- Prior art keywords
- recombinant baculovirus
- pct
- recombinant
- spodoptera frugiperda
- present
- Prior art date
Links
- 241000701447 unidentified baculovirus Species 0.000 title abstract 4
- 241000256251 Spodoptera frugiperda Species 0.000 title abstract 2
- 230000002188 osteogenic effect Effects 0.000 title abstract 2
- 108010049870 Bone Morphogenetic Protein 7 Proteins 0.000 abstract 4
- 102100022544 Bone morphogenetic protein 7 Human genes 0.000 abstract 4
- 241000238631 Hexapoda Species 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000020084 Bone disease Diseases 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 101000899361 Homo sapiens Bone morphogenetic protein 7 Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 102000046107 human BMP7 Human genes 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000399 orthopedic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD920007A IT1259042B (it) | 1992-01-27 | 1992-01-27 | Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE178651T1 true ATE178651T1 (de) | 1999-04-15 |
Family
ID=11389773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93902252T ATE178651T1 (de) | 1992-01-27 | 1993-01-27 | Expression von osteogenem faktor op-1 in mit rekombinantem baculovirus infizierten spodoptera frugiperda-zellen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5641649A (de) |
| EP (1) | EP0625198B1 (de) |
| AT (1) | ATE178651T1 (de) |
| DE (1) | DE69324345T2 (de) |
| ES (1) | ES2134254T3 (de) |
| IT (1) | IT1259042B (de) |
| WO (1) | WO1993015197A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610021A (en) * | 1992-02-21 | 1997-03-11 | Creative Biomolecules, Inc. | Compositions and methods for identification and use of soluble complex forms of osteogenic proteins |
| JPH08510446A (ja) * | 1993-03-04 | 1996-11-05 | クリエイティブ バイオモレキュルズ，インコーポレイテッド | 組換え骨形成タンパク質を生成するための方法および組成物 |
| EP0626451A3 (de) * | 1993-05-27 | 1997-11-05 | Takeda Chemical Industries, Ltd. | Heterodimere einer TGF-Beta Superfamilie |
| KR970043049A (ko) * | 1995-12-28 | 1997-07-26 | 성재갑 | 효모를 이용한 골 생성 단백질- 1의 제조방법 |
| US20010016646A1 (en) | 1998-03-20 | 2001-08-23 | David C. Rueger | Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects |
| US7041641B2 (en) * | 1997-03-20 | 2006-05-09 | Stryker Corporation | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects |
| US6949357B2 (en) * | 1997-06-05 | 2005-09-27 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the urinary tract |
| EP2056852A4 (de) * | 2006-07-27 | 2010-01-13 | Centocor Ortho Biotech Inc | Bmp-7-varianten-zusammensetzungen, verfahren und verwendungen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58011B1 (en) * | 1983-05-27 | 1993-06-16 | Texas A & M Univ Sys | Method for producing a recombinant baculovirus expression vector |
| US5221620A (en) * | 1987-10-06 | 1993-06-22 | Oncogen | Cloning and expression of transforming growth factor β2 |
| CA2005120A1 (en) * | 1988-12-15 | 1990-06-15 | Anthony F. Purchio | Tgf-beta 1/beta 2: a novel chimeric transforming growth factor-beta |
| DE69031939T2 (de) * | 1989-03-28 | 1998-09-10 | Genetics Institute, Inc., Cambridge, Mass. | Osteoinduktive zusammensetzungen |
| US5155037A (en) * | 1989-08-04 | 1992-10-13 | The Texas A&M University System | Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems |
| WO1991005802A1 (en) * | 1989-10-17 | 1991-05-02 | Creative Biomolecules, Inc. | Osteogenic devices |
| GB9023111D0 (en) * | 1990-10-24 | 1990-12-05 | Wellcome Found | Expression system |
-
1992
- 1992-01-27 IT ITPD920007A patent/IT1259042B/it active IP Right Grant
-
1993
- 1993-01-27 DE DE69324345T patent/DE69324345T2/de not_active Expired - Lifetime
- 1993-01-27 EP EP93902252A patent/EP0625198B1/de not_active Expired - Lifetime
- 1993-01-27 AT AT93902252T patent/ATE178651T1/de not_active IP Right Cessation
- 1993-01-27 WO PCT/EP1993/000183 patent/WO1993015197A2/en not_active Ceased
- 1993-01-27 US US08/256,368 patent/US5641649A/en not_active Expired - Lifetime
- 1993-01-27 ES ES93902252T patent/ES2134254T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0625198B1 (de) | 1999-04-07 |
| EP0625198A1 (de) | 1994-11-23 |
| ES2134254T3 (es) | 1999-10-01 |
| IT1259042B (it) | 1996-03-11 |
| DE69324345T2 (de) | 1999-11-25 |
| US5641649A (en) | 1997-06-24 |
| WO1993015197A3 (en) | 1993-09-16 |
| ITPD920007A0 (it) | 1992-01-27 |
| WO1993015197A2 (en) | 1993-08-05 |
| DE69324345D1 (de) | 1999-05-12 |
| ITPD920007A1 (it) | 1993-07-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |