EP2056852A4 - Bmp-7-varianten-zusammensetzungen, verfahren und verwendungen - Google Patents

Bmp-7-varianten-zusammensetzungen, verfahren und verwendungen

Info

Publication number
EP2056852A4
EP2056852A4 EP07798210A EP07798210A EP2056852A4 EP 2056852 A4 EP2056852 A4 EP 2056852A4 EP 07798210 A EP07798210 A EP 07798210A EP 07798210 A EP07798210 A EP 07798210A EP 2056852 A4 EP2056852 A4 EP 2056852A4
Authority
EP
European Patent Office
Prior art keywords
bmp
methods
variant compositions
variant
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07798210A
Other languages
English (en)
French (fr)
Other versions
EP2056852A2 (de
Inventor
Bernard Amegadzie
Mark R Cunningham
Haimanti Dorai
Jeffrey Luo
Juliane Mills
Bethany Swencki-Underwood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of EP2056852A2 publication Critical patent/EP2056852A2/de
Publication of EP2056852A4 publication Critical patent/EP2056852A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP07798210A 2006-07-27 2007-06-07 Bmp-7-varianten-zusammensetzungen, verfahren und verwendungen Withdrawn EP2056852A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82053806P 2006-07-27 2006-07-27
PCT/US2007/070584 WO2008014054A2 (en) 2006-07-27 2007-06-07 Bmp-7 variant compositions, methods and uses

Publications (2)

Publication Number Publication Date
EP2056852A2 EP2056852A2 (de) 2009-05-13
EP2056852A4 true EP2056852A4 (de) 2010-01-13

Family

ID=38982164

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07798210A Withdrawn EP2056852A4 (de) 2006-07-27 2007-06-07 Bmp-7-varianten-zusammensetzungen, verfahren und verwendungen

Country Status (3)

Country Link
EP (1) EP2056852A4 (de)
JP (1) JP2009544325A (de)
WO (1) WO2008014054A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101274930B1 (ko) * 2011-06-03 2013-06-17 전남대학교산학협력단 골 형성 또는 혈관신생 촉진용 펩타이드 ｂｆｐ 4 및 이의 용도
KR101279145B1 (ko) * 2012-08-10 2013-06-26 주식회사 셀루메드 활성형 ｂｍｐ7의 생산율 증가 방법
GB201412290D0 (en) 2014-07-10 2014-08-27 Cambridge Entpr Ltd Novel use

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003600A1 (en) * 1992-07-31 1994-02-17 Creative Biomolecules, Inc. Morphogenic protein soluble complex and composition thereof
WO1999003887A1 (en) * 1997-07-14 1999-01-28 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins
WO1999037320A1 (en) * 1998-01-23 1999-07-29 Creative Biomolecules, Inc. Methods and compositions for enhancing cognitive function using morphogenic proteins
US20050114037A1 (en) * 2003-03-31 2005-05-26 Xencor, Inc. Methods for rational pegylation of proteins
WO2005097825A2 (en) * 2004-03-31 2005-10-20 Xencor, Inc. Bmp-7 variants with improved properties
WO2007087053A2 (en) * 2005-12-22 2007-08-02 Centocor, Inc Bmp-7 variant compositions, methods and uses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108901A (en) * 1988-09-02 1992-04-28 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
IT1259042B (it) * 1992-01-27 1996-03-11 Mini Ricerca Scient Tecnolog Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
US6677432B1 (en) * 1998-10-07 2004-01-13 Stryker Corporation Mutations of the C-terminal portion of TGF-β superfamily proteins

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003600A1 (en) * 1992-07-31 1994-02-17 Creative Biomolecules, Inc. Morphogenic protein soluble complex and composition thereof
WO1999003887A1 (en) * 1997-07-14 1999-01-28 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins
WO1999037320A1 (en) * 1998-01-23 1999-07-29 Creative Biomolecules, Inc. Methods and compositions for enhancing cognitive function using morphogenic proteins
US20050114037A1 (en) * 2003-03-31 2005-05-26 Xencor, Inc. Methods for rational pegylation of proteins
WO2005097825A2 (en) * 2004-03-31 2005-10-20 Xencor, Inc. Bmp-7 variants with improved properties
WO2007087053A2 (en) * 2005-12-22 2007-08-02 Centocor, Inc Bmp-7 variant compositions, methods and uses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SWENCKI-UNDERWOOD ET AL: "Expression and characterization of a human BMP-7 variant with improved biochemical properties", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, vol. 57, no. 2, 21 December 2007 (2007-12-21), pages 312 - 319, XP022398606, ISSN: 1046-5928 *

Also Published As

Publication number Publication date
EP2056852A2 (de) 2009-05-13
WO2008014054A3 (en) 2009-04-09
JP2009544325A (ja) 2009-12-17
WO2008014054A2 (en) 2008-01-31

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Legal Events

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AX Request for extension of the european patent

Extension state: AL BA HR MK RS

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 38/18 20060101ALI20090506BHEP

Ipc: A61K 38/16 20060101ALI20090506BHEP

Ipc: C07K 14/00 20060101ALI20090506BHEP

Ipc: C07K 14/51 20060101ALI20090506BHEP

Ipc: C07K 14/475 20060101ALI20090506BHEP

Ipc: C07K 14/46 20060101ALI20090506BHEP

Ipc: C07K 14/435 20060101ALI20090506BHEP

Ipc: C12N 15/63 20060101ALI20090506BHEP

Ipc: C12N 15/12 20060101ALI20090506BHEP

Ipc: C12N 15/00 20060101AFI20090506BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CENTOCOR ORTHO BIOTECH INC.

A4 Supplementary search report drawn up and despatched

Effective date: 20091215

17Q First examination report despatched

Effective date: 20100409

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: JANSSEN BIOTECH, INC.

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