JP2009544325A - Ｂｍｐ−７変異体組成物、方法および使用 - Google Patents

Ｂｍｐ−７変異体組成物、方法および使用 Download PDF

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Publication number
JP2009544325A
JP2009544325A JP2009521874A JP2009521874A JP2009544325A JP 2009544325 A JP2009544325 A JP 2009544325A JP 2009521874 A JP2009521874 A JP 2009521874A JP 2009521874 A JP2009521874 A JP 2009521874A JP 2009544325 A JP2009544325 A JP 2009544325A
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JP
Japan
Prior art keywords
seq
nucleic acid
sequence shown
acid sequence
peptide chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009521874A
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English (en)
Japanese (ja)
Inventor
アメガジー，バーナード
カニンガム，マーク・アール
ドレイ，ハイマンテイ
ルオ，ジエフリー
ミルズ，ジユリアン
スウエンキ−アンダーウツド，ベサニー
Original Assignee
セントカー・インコーポレーテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by セントカー・インコーポレーテツド filed Critical セントカー・インコーポレーテツド
Publication of JP2009544325A publication Critical patent/JP2009544325A/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009521874A 2006-07-27 2007-06-07 Ｂｍｐ−７変異体組成物、方法および使用 Pending JP2009544325A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82053806P 2006-07-27 2006-07-27
PCT/US2007/070584 WO2008014054A2 (en) 2006-07-27 2007-06-07 Bmp-7 variant compositions, methods and uses

Publications (1)

Publication Number Publication Date
JP2009544325A true JP2009544325A (ja) 2009-12-17

Family

ID=38982164

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009521874A Pending JP2009544325A (ja) 2006-07-27 2007-06-07 Ｂｍｐ−７変異体組成物、方法および使用

Country Status (3)

Country Link
EP (1) EP2056852A4 (de)
JP (1) JP2009544325A (de)
WO (1) WO2008014054A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014516547A (ja) * 2011-06-03 2014-07-17 チョンナム ナショナル ユニバーシティ ホスピタル 骨形成または血管新生促進用ペプチドｂｆｐ４およびその用途

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101279145B1 (ko) * 2012-08-10 2013-06-26 주식회사 셀루메드 활성형 ｂｍｐ7의 생산율 증가 방법
GB201412290D0 (en) 2014-07-10 2014-08-27 Cambridge Entpr Ltd Novel use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005290016A (ja) * 1998-10-07 2005-10-20 Stryker Corp ＴＧＦ−βスーパーファミリー間のキメラタンパク質
JP2009521220A (ja) * 2005-12-22 2009-06-04 セントカー・インコーポレーテツド Ｂｍｐ−７変異体組成物、方法および使用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108901A (en) * 1988-09-02 1992-04-28 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
IT1259042B (it) * 1992-01-27 1996-03-11 Mini Ricerca Scient Tecnolog Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
KR950702627A (ko) * 1992-07-31 1995-07-29 찰스 엠. 코헨 모르포겐 단백질의 가용성 복합체 및 그의 조성물(Morphogenic Protein Soluble Complex and Composition Thereof)
IL133974A0 (en) * 1997-07-14 2001-04-30 Bolder Biotechnology Inc Derivatives of growth hormone and related proteins
US20030170213A1 (en) * 1998-01-23 2003-09-11 Marc F. Charette Methods and compositions for enhancing cognitive function using morphogenic proteins
US7610156B2 (en) * 2003-03-31 2009-10-27 Xencor, Inc. Methods for rational pegylation of proteins
EP1730186A2 (de) * 2004-03-31 2006-12-13 Xencor, Inc. Bmp-7 varianten mit verbesserten eigenschaften

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005290016A (ja) * 1998-10-07 2005-10-20 Stryker Corp ＴＧＦ−βスーパーファミリー間のキメラタンパク質
JP2009521220A (ja) * 2005-12-22 2009-06-04 セントカー・インコーポレーテツド Ｂｍｐ−７変異体組成物、方法および使用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014516547A (ja) * 2011-06-03 2014-07-17 チョンナム ナショナル ユニバーシティ ホスピタル 骨形成または血管新生促進用ペプチドｂｆｐ４およびその用途

Also Published As

Publication number Publication date
WO2008014054A3 (en) 2009-04-09
EP2056852A2 (de) 2009-05-13
WO2008014054A2 (en) 2008-01-31
EP2056852A4 (de) 2010-01-13

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