EP2056852A4 - Compositions à base de variantes de bmp-7, procédés et utilisations - Google Patents
Compositions à base de variantes de bmp-7, procédés et utilisationsInfo
- Publication number
- EP2056852A4 EP2056852A4 EP07798210A EP07798210A EP2056852A4 EP 2056852 A4 EP2056852 A4 EP 2056852A4 EP 07798210 A EP07798210 A EP 07798210A EP 07798210 A EP07798210 A EP 07798210A EP 2056852 A4 EP2056852 A4 EP 2056852A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- bmp
- methods
- variant compositions
- variant
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82053806P | 2006-07-27 | 2006-07-27 | |
PCT/US2007/070584 WO2008014054A2 (fr) | 2006-07-27 | 2007-06-07 | Compositions à base de variantes de bmp-7, procédés et utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2056852A2 EP2056852A2 (fr) | 2009-05-13 |
EP2056852A4 true EP2056852A4 (fr) | 2010-01-13 |
Family
ID=38982164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07798210A Withdrawn EP2056852A4 (fr) | 2006-07-27 | 2007-06-07 | Compositions à base de variantes de bmp-7, procédés et utilisations |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2056852A4 (fr) |
JP (1) | JP2009544325A (fr) |
WO (1) | WO2008014054A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101274930B1 (ko) * | 2011-06-03 | 2013-06-17 | 전남대학교산학협력단 | 골 형성 또는 혈관신생 촉진용 펩타이드 bfp 4 및 이의 용도 |
KR101279145B1 (ko) * | 2012-08-10 | 2013-06-26 | 주식회사 셀루메드 | 활성형 bmp7의 생산율 증가 방법 |
GB201412290D0 (en) | 2014-07-10 | 2014-08-27 | Cambridge Entpr Ltd | Novel use |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003600A1 (fr) * | 1992-07-31 | 1994-02-17 | Creative Biomolecules, Inc. | Complexe soluble de proteines morphogeniques et sa composition |
WO1999003887A1 (fr) * | 1997-07-14 | 1999-01-28 | Bolder Biotechnology, Inc. | Derives d'hormone de croissance et proteines associees |
WO1999037320A1 (fr) * | 1998-01-23 | 1999-07-29 | Creative Biomolecules, Inc. | Procedes et compositions pour ameliorer la fonction cognitive au moyen de proteines morphogeniques |
US20050114037A1 (en) * | 2003-03-31 | 2005-05-26 | Xencor, Inc. | Methods for rational pegylation of proteins |
WO2005097825A2 (fr) * | 2004-03-31 | 2005-10-20 | Xencor, Inc. | Variants de bmp-7 ayant des proprietes ameliorees |
WO2007087053A2 (fr) * | 2005-12-22 | 2007-08-02 | Centocor, Inc | Compositions à base de variantes de bmp-7, procédés et utilisations |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5108901A (en) * | 1988-09-02 | 1992-04-28 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
IT1259042B (it) * | 1992-01-27 | 1996-03-11 | Mini Ricerca Scient Tecnolog | Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante |
US6677432B1 (en) * | 1998-10-07 | 2004-01-13 | Stryker Corporation | Mutations of the C-terminal portion of TGF-β superfamily proteins |
-
2007
- 2007-06-07 EP EP07798210A patent/EP2056852A4/fr not_active Withdrawn
- 2007-06-07 JP JP2009521874A patent/JP2009544325A/ja active Pending
- 2007-06-07 WO PCT/US2007/070584 patent/WO2008014054A2/fr active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003600A1 (fr) * | 1992-07-31 | 1994-02-17 | Creative Biomolecules, Inc. | Complexe soluble de proteines morphogeniques et sa composition |
WO1999003887A1 (fr) * | 1997-07-14 | 1999-01-28 | Bolder Biotechnology, Inc. | Derives d'hormone de croissance et proteines associees |
WO1999037320A1 (fr) * | 1998-01-23 | 1999-07-29 | Creative Biomolecules, Inc. | Procedes et compositions pour ameliorer la fonction cognitive au moyen de proteines morphogeniques |
US20050114037A1 (en) * | 2003-03-31 | 2005-05-26 | Xencor, Inc. | Methods for rational pegylation of proteins |
WO2005097825A2 (fr) * | 2004-03-31 | 2005-10-20 | Xencor, Inc. | Variants de bmp-7 ayant des proprietes ameliorees |
WO2007087053A2 (fr) * | 2005-12-22 | 2007-08-02 | Centocor, Inc | Compositions à base de variantes de bmp-7, procédés et utilisations |
Non-Patent Citations (1)
Title |
---|
SWENCKI-UNDERWOOD ET AL: "Expression and characterization of a human BMP-7 variant with improved biochemical properties", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, vol. 57, no. 2, 21 December 2007 (2007-12-21), pages 312 - 319, XP022398606, ISSN: 1046-5928 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008014054A2 (fr) | 2008-01-31 |
WO2008014054A3 (fr) | 2009-04-09 |
EP2056852A2 (fr) | 2009-05-13 |
JP2009544325A (ja) | 2009-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090227 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 38/18 20060101ALI20090506BHEP Ipc: A61K 38/16 20060101ALI20090506BHEP Ipc: C07K 14/00 20060101ALI20090506BHEP Ipc: C07K 14/51 20060101ALI20090506BHEP Ipc: C07K 14/475 20060101ALI20090506BHEP Ipc: C07K 14/46 20060101ALI20090506BHEP Ipc: C07K 14/435 20060101ALI20090506BHEP Ipc: C12N 15/63 20060101ALI20090506BHEP Ipc: C12N 15/12 20060101ALI20090506BHEP Ipc: C12N 15/00 20060101AFI20090506BHEP |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: CENTOCOR ORTHO BIOTECH INC. |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20091215 |
|
17Q | First examination report despatched |
Effective date: 20100409 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: JANSSEN BIOTECH, INC. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20121016 |