WO2008014054A3 - Compositions à base de variantes de bmp-7, procédés et utilisations - Google Patents
Compositions à base de variantes de bmp-7, procédés et utilisations Download PDFInfo
- Publication number
- WO2008014054A3 WO2008014054A3 PCT/US2007/070584 US2007070584W WO2008014054A3 WO 2008014054 A3 WO2008014054 A3 WO 2008014054A3 US 2007070584 W US2007070584 W US 2007070584W WO 2008014054 A3 WO2008014054 A3 WO 2008014054A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- bmp
- variant compositions
- peptide chains
- variant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne des chaînes de peptides de variantes de hBMP-7 (Human Bone Morphogenic Protein), des acides nucléiques codant ces chaînes de peptides, ainsi que des procédés de fabrication et d'utilisation de ces chaînes de peptides.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07798210A EP2056852A4 (fr) | 2006-07-27 | 2007-06-07 | Compositions à base de variantes de bmp-7, procédés et utilisations |
JP2009521874A JP2009544325A (ja) | 2006-07-27 | 2007-06-07 | Bmp−7変異体組成物、方法および使用 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82053806P | 2006-07-27 | 2006-07-27 | |
US60/820,538 | 2006-07-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008014054A2 WO2008014054A2 (fr) | 2008-01-31 |
WO2008014054A3 true WO2008014054A3 (fr) | 2009-04-09 |
Family
ID=38982164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/070584 WO2008014054A2 (fr) | 2006-07-27 | 2007-06-07 | Compositions à base de variantes de bmp-7, procédés et utilisations |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2056852A4 (fr) |
JP (1) | JP2009544325A (fr) |
WO (1) | WO2008014054A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101274930B1 (ko) * | 2011-06-03 | 2013-06-17 | 전남대학교산학협력단 | 골 형성 또는 혈관신생 촉진용 펩타이드 bfp 4 및 이의 용도 |
KR101279145B1 (ko) * | 2012-08-10 | 2013-06-26 | 주식회사 셀루메드 | 활성형 bmp7의 생산율 증가 방법 |
GB201412290D0 (en) | 2014-07-10 | 2014-08-27 | Cambridge Entpr Ltd | Novel use |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5108901A (en) * | 1988-09-02 | 1992-04-28 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
US5641649A (en) * | 1992-01-27 | 1997-06-24 | Italian Ministry For Universities And Scientific And Technological Research | Expression of osteogenic factor OP-1 in cells of spodoptera frugiperda infected with recombinant baculovirus |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE287949T1 (de) * | 1992-07-31 | 2005-02-15 | Stryker Corp | Löslicher komplex morphogener proteine und zusammensetzungen davon |
CA2296770A1 (fr) * | 1997-07-14 | 1999-01-28 | Bolder Biotechnology, Inc. | Derives d'hormone de croissance et proteines associees |
US20030170213A1 (en) * | 1998-01-23 | 2003-09-11 | Marc F. Charette | Methods and compositions for enhancing cognitive function using morphogenic proteins |
US6677432B1 (en) * | 1998-10-07 | 2004-01-13 | Stryker Corporation | Mutations of the C-terminal portion of TGF-β superfamily proteins |
US7610156B2 (en) * | 2003-03-31 | 2009-10-27 | Xencor, Inc. | Methods for rational pegylation of proteins |
WO2005097825A2 (fr) * | 2004-03-31 | 2005-10-20 | Xencor, Inc. | Variants de bmp-7 ayant des proprietes ameliorees |
JP5100662B2 (ja) * | 2005-12-22 | 2012-12-19 | セントカー・インコーポレーテツド | Bmp−7変異体組成物、方法および使用 |
-
2007
- 2007-06-07 WO PCT/US2007/070584 patent/WO2008014054A2/fr active Application Filing
- 2007-06-07 EP EP07798210A patent/EP2056852A4/fr not_active Withdrawn
- 2007-06-07 JP JP2009521874A patent/JP2009544325A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5108901A (en) * | 1988-09-02 | 1992-04-28 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
US5641649A (en) * | 1992-01-27 | 1997-06-24 | Italian Ministry For Universities And Scientific And Technological Research | Expression of osteogenic factor OP-1 in cells of spodoptera frugiperda infected with recombinant baculovirus |
Non-Patent Citations (1)
Title |
---|
See also references of EP2056852A4 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008014054A2 (fr) | 2008-01-31 |
EP2056852A4 (fr) | 2010-01-13 |
EP2056852A2 (fr) | 2009-05-13 |
JP2009544325A (ja) | 2009-12-17 |
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