ATE154611T1 - Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellung - Google Patents
Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellungInfo
- Publication number
- ATE154611T1 ATE154611T1 AT89910667T AT89910667T ATE154611T1 AT E154611 T1 ATE154611 T1 AT E154611T1 AT 89910667 T AT89910667 T AT 89910667T AT 89910667 T AT89910667 T AT 89910667T AT E154611 T1 ATE154611 T1 AT E154611T1
- Authority
- AT
- Austria
- Prior art keywords
- stimulating factor
- cell strain
- factor
- colony stimulating
- human
- Prior art date
Links
- 102000007644 Colony-Stimulating Factors Human genes 0.000 title abstract 4
- 108010071942 Colony-Stimulating Factors Proteins 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 6
- 230000000694 effects Effects 0.000 abstract 2
- 210000000066 myeloid cell Anatomy 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000006228 supernatant Substances 0.000 abstract 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 201000005202 lung cancer Diseases 0.000 abstract 1
- 208000020816 lung neoplasm Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23472288 | 1988-09-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE154611T1 true ATE154611T1 (de) | 1997-07-15 |
Family
ID=16975349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89910667T ATE154611T1 (de) | 1988-09-21 | 1989-09-21 | Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellung |
Country Status (5)
Country | Link |
---|---|
US (1) | US5258324A (de) |
EP (1) | EP0516845B1 (de) |
AT (1) | ATE154611T1 (de) |
DE (1) | DE68928138T2 (de) |
WO (1) | WO1990003397A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5260417A (en) * | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
US5326558A (en) * | 1989-08-08 | 1994-07-05 | Genetics Institute, Inc. | Megakaryocytopoietic factor |
US6433142B1 (en) | 1989-08-08 | 2002-08-13 | Genetics Institute, Llc | Megakaryocyte stimulating factors |
KR930700549A (ko) * | 1990-05-31 | 1993-03-15 | 아키라 사사이 | 신규한 거핵구계 콜로니 자극인자와 그 제조방법 |
JPH06502621A (ja) * | 1990-07-02 | 1994-03-24 | ヒップル キャンサー リサーチ センター | ヒトmeg―csfタンパク質と方法 |
HU218893B (hu) * | 1994-03-31 | 2000-12-28 | Amgen Inc. | A megakariocita szaporodás és differenciálódás stimulálására szolgáló módszerek és vízoldható készítmények |
US5795569A (en) * | 1994-03-31 | 1998-08-18 | Amgen Inc. | Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62282580A (ja) * | 1986-04-29 | 1987-12-08 | Asahi Chem Ind Co Ltd | 殺腫瘍性クロ−ン化ヒトキラ−t細胞および該細胞より得たt細胞抗原リセプタ− |
US4965195A (en) * | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
-
1989
- 1989-09-21 WO PCT/JP1989/000960 patent/WO1990003397A1/ja active IP Right Grant
- 1989-09-21 EP EP89910667A patent/EP0516845B1/de not_active Expired - Lifetime
- 1989-09-21 US US07/668,493 patent/US5258324A/en not_active Expired - Fee Related
- 1989-09-21 AT AT89910667T patent/ATE154611T1/de not_active IP Right Cessation
- 1989-09-21 DE DE68928138T patent/DE68928138T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0516845B1 (de) | 1997-06-18 |
EP0516845A1 (de) | 1992-12-09 |
DE68928138D1 (de) | 1997-07-24 |
EP0516845A4 (de) | 1991-09-23 |
DE68928138T2 (de) | 1997-10-02 |
WO1990003397A1 (en) | 1990-04-05 |
US5258324A (en) | 1993-11-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL112585A (en) | N-terminally chemically modified G-CSF and analogs process for their preparation and pharmaceutical compositions containing them | |
NZ237661A (en) | Growth regulatory proteins (epithelins) their production and diagnostic and therapeutic uses | |
ATE135577T1 (de) | Verwendung von buspiron zur herstellung eines pharmazeutischen präparats zur behandlung der alkoholsucht | |
ATE165010T1 (de) | Menschliches ifn-beta2/il-6, dessen reinigung und verwendungen | |
CA2019363A1 (en) | Dna and use thereof | |
ATE130365T1 (de) | Bakterien transformiert mit expressionsplasmiden, die für den menschlichen neurothrophen wimper faktor (h-cntf) kodieren, ihre verwendung in der herstellung von h-cntf, antikörper gegen h-cntf und die anwendung von h-cntf in medizischer behandlung. | |
GB1517540A (en) | Preparation for the treatment of infectious diseases method for the manufacture thereof and its use | |
Kitamura et al. | Regulation of mast cell differentiation | |
KR960000394B1 (ko) | 백혈구 감소증 치료제의 제조방법 | |
ATE69241T1 (de) | Herstellung von polypeptiden mit humangammainterferon-aktivitaet. | |
EP0291804A3 (de) | Proteine mit TNF-Wirkung | |
ATE154611T1 (de) | Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellung | |
DE69012377D1 (de) | Polypeptid und dessen Herstellung. | |
DE69333412D1 (de) | Übergangszustand-analoga des kokains, ihre verwendung zur herstellung von kataltischen antikörpern gegen kokain und verwendung derselben in diagnose und therapie | |
EP0672684A4 (de) | Neuer megakaryot-kolonie-stimulierender faktor und seine herstellung. | |
DE3874376D1 (de) | Verfahren zur herstellung eines konzentrates von alpha-1-antitrypsin von menschlicher plasmafraktion und seine verwendung als arzneimittel. | |
ATE164882T1 (de) | Verfahren zur herstellung von aktivierten killer- monozyten und verfahren zur überprüfung ihrer tumoriziden aktivität | |
ATE101521T1 (de) | Ein reines faktor i-protein und verfahren zur herstellung. | |
US1905848A (en) | Zirconium citrate hexamethylenetetramine | |
Taichman et al. | Maturation of human gingival keratinocytes cultured with fibroblasts from keratinizing and non-keratinizing epithelia | |
ATE185484T1 (de) | Verwendung von adenosin zur herstellung eines arzneimittels zur behandlung entzüdlicher reaktionen der lunge | |
HU9800554D0 (en) | Process for producing human leukocyte (alpha) interferon | |
CN1220997A (zh) | 重组人肿瘤坏死因子及制备方法 | |
JPH0724595B2 (ja) | サイトカインを製造する方法 | |
CU22041A1 (es) | Procedimiento para la obtencion de factor de transferencia leucocitario. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |