DE68928138T2 - Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellung - Google Patents
Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellungInfo
- Publication number
- DE68928138T2 DE68928138T2 DE68928138T DE68928138T DE68928138T2 DE 68928138 T2 DE68928138 T2 DE 68928138T2 DE 68928138 T DE68928138 T DE 68928138T DE 68928138 T DE68928138 T DE 68928138T DE 68928138 T2 DE68928138 T2 DE 68928138T2
- Authority
- DE
- Germany
- Prior art keywords
- stimulating factor
- cell strain
- factor
- colony stimulating
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102000007644 Colony-Stimulating Factors Human genes 0.000 title abstract 4
- 108010071942 Colony-Stimulating Factors Proteins 0.000 title abstract 4
- 210000004027 cell Anatomy 0.000 abstract 6
- 230000000694 effects Effects 0.000 abstract 2
- 210000000066 myeloid cell Anatomy 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000006228 supernatant Substances 0.000 abstract 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 201000005202 lung cancer Diseases 0.000 abstract 1
- 208000020816 lung neoplasm Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23472288 | 1988-09-21 | ||
| PCT/JP1989/000960 WO1990003397A1 (en) | 1988-09-21 | 1989-09-21 | Novel megakaryocytic colony stimulating factor and process for its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE68928138D1 DE68928138D1 (de) | 1997-07-24 |
| DE68928138T2 true DE68928138T2 (de) | 1997-10-02 |
Family
ID=16975349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE68928138T Expired - Fee Related DE68928138T2 (de) | 1988-09-21 | 1989-09-21 | Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellung |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5258324A (de) |
| EP (1) | EP0516845B1 (de) |
| AT (1) | ATE154611T1 (de) |
| DE (1) | DE68928138T2 (de) |
| WO (1) | WO1990003397A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260417A (en) * | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
| US6433142B1 (en) | 1989-08-08 | 2002-08-13 | Genetics Institute, Llc | Megakaryocyte stimulating factors |
| US5326558A (en) * | 1989-08-08 | 1994-07-05 | Genetics Institute, Inc. | Megakaryocytopoietic factor |
| CA2084074A1 (en) * | 1990-05-31 | 1991-12-01 | Keita Matsunaga | Megakaryocyte colony stimulating factor and production thereof |
| JPH06502621A (ja) * | 1990-07-02 | 1994-03-24 | ヒップル キャンサー リサーチ センター | ヒトｍｅｇ―ｃｓｆタンパク質と方法 |
| HU218893B (hu) * | 1994-03-31 | 2000-12-28 | Amgen Inc. | A megakariocita szaporodás és differenciálódás stimulálására szolgáló módszerek és vízoldható készítmények |
| US5795569A (en) * | 1994-03-31 | 1998-08-18 | Amgen Inc. | Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62282580A (ja) * | 1986-04-29 | 1987-12-08 | Asahi Chem Ind Co Ltd | 殺腫瘍性クロ−ン化ヒトキラ−ｔ細胞および該細胞より得たｔ細胞抗原リセプタ− |
| US4965195A (en) * | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
-
1989
- 1989-09-21 WO PCT/JP1989/000960 patent/WO1990003397A1/ja active IP Right Grant
- 1989-09-21 DE DE68928138T patent/DE68928138T2/de not_active Expired - Fee Related
- 1989-09-21 EP EP89910667A patent/EP0516845B1/de not_active Expired - Lifetime
- 1989-09-21 US US07/668,493 patent/US5258324A/en not_active Expired - Fee Related
- 1989-09-21 AT AT89910667T patent/ATE154611T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0516845A4 (de) | 1991-09-23 |
| EP0516845B1 (de) | 1997-06-18 |
| WO1990003397A1 (en) | 1990-04-05 |
| DE68928138D1 (de) | 1997-07-24 |
| EP0516845A1 (de) | 1992-12-09 |
| US5258324A (en) | 1993-11-02 |
| ATE154611T1 (de) | 1997-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |