NZ505193A
(en)
|
1997-12-22 |
2003-03-28 |
Euro Celtique S |
Opioid agonist/antagonist combinations
|
ATE275402T1
(de)
|
1999-11-01 |
2004-09-15 |
John Rhodes |
Arzneimittel zur behandlung von darmverstopfung und reizkolon
|
ES2326730T3
(es)
*
|
2000-02-08 |
2009-10-19 |
Euro-Celtique S.A. |
Formulaciones orales de agonistas opioides resistentes a manipulaciones indebidas.
|
JP4522652B2
(ja)
|
2001-05-11 |
2010-08-11 |
エンドー ファーマシューティカルズ, インコーポレイティド |
乱用防止制御放出オピオイド投薬形態
|
ES2319620T3
(es)
|
2001-07-18 |
2009-05-11 |
Euro-Celtique S.A. |
Conbinaciones farmaceuticas de oxicodona y naloxona.
|
DK1414451T3
(da)
|
2001-08-06 |
2009-08-10 |
Euro Celtique Sa |
Opioidagonistformuleringer med frigivelig og sekvenstreret antagonist
|
AU2002324624A1
(en)
|
2001-08-06 |
2003-02-24 |
Euro-Celtique S.A. |
Sequestered antagonist formulations
|
EP2425823A1
(en)
*
|
2002-04-05 |
2012-03-07 |
Euro-Celtique S.A. |
Pharmaceutical preparation containing oxycodone and naloxone
|
US7501433B2
(en)
*
|
2002-05-17 |
2009-03-10 |
Jenken Biosciences, Inc. |
Opioid and opioid-like compounds and uses thereof
|
WO2004026283A1
(en)
|
2002-09-20 |
2004-04-01 |
Alpharma, Inc. |
Sequestering subunit and related compositions and metohds
|
EP1911763B1
(en)
|
2003-01-28 |
2010-08-11 |
Ironwood Pharmaceuticals, Inc. |
Compositions for the treatment of gastrointestinal disorders
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
BRPI0409128A
(pt)
*
|
2003-04-08 |
2006-03-28 |
Progenics Pharm Inc |
uso de antagonistas de opióides periféricos, especialmente metilnaltrexona para tratar sìndrome de intestino irritável
|
US20040202717A1
(en)
|
2003-04-08 |
2004-10-14 |
Mehta Atul M. |
Abuse-resistant oral dosage forms and method of use thereof
|
ES2527870T5
(es)
|
2003-04-08 |
2022-10-14 |
Progenics Pharm Inc |
Formulaciones farmacéuticas que contienen metilnaltrexona
|
TWI347201B
(en)
|
2003-04-21 |
2011-08-21 |
Euro Celtique Sa |
Pharmaceutical products,uses thereof and methods for preparing the same
|
US8017622B2
(en)
|
2003-05-16 |
2011-09-13 |
Jenken Biosciences, Inc. |
Opioid and opioid-like compounds and uses thereof
|
PT1729797E
(pt)
*
|
2004-03-22 |
2008-12-17 |
Solvay Pharm Gmbh |
Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
|
TW200633721A
(en)
*
|
2004-12-14 |
2006-10-01 |
Shionogi & Co |
A pharmaceutical composition for treating constipation
|
EP1702558A1
(en)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Method and device for the assessment of bowel function
|
US8518962B2
(en)
|
2005-03-07 |
2013-08-27 |
The University Of Chicago |
Use of opioid antagonists
|
US8524731B2
(en)
|
2005-03-07 |
2013-09-03 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
US9662325B2
(en)
|
2005-03-07 |
2017-05-30 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
WO2006096626A2
(en)
|
2005-03-07 |
2006-09-14 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
AR057035A1
(es)
|
2005-05-25 |
2007-11-14 |
Progenics Pharm Inc |
SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
|
AR057325A1
(es)
|
2005-05-25 |
2007-11-28 |
Progenics Pharm Inc |
Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
|
US20070148151A1
(en)
|
2005-07-29 |
2007-06-28 |
Martin Frink |
Processes for the manufacture and use of pancreatin
|
US11266607B2
(en)
*
|
2005-08-15 |
2022-03-08 |
AbbVie Pharmaceuticals GmbH |
Process for the manufacture and use of pancreatin micropellet cores
|
US9198871B2
(en)
*
|
2005-08-15 |
2015-12-01 |
Abbott Products Gmbh |
Delayed release pancreatin compositions
|
US20070185145A1
(en)
*
|
2006-02-03 |
2007-08-09 |
Royds Robert B |
Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same
|
WO2007123865A2
(en)
*
|
2006-04-19 |
2007-11-01 |
Smith Jill P |
Treatment of inflammatory and ulcerative diseases of the bowel with opioid antagonists
|
US10072256B2
(en)
*
|
2006-05-22 |
2018-09-11 |
Abbott Products Gmbh |
Process for separating and determining the viral load in a pancreatin sample
|
PL2526932T3
(pl)
|
2006-06-19 |
2017-12-29 |
Alpharma Pharmaceuticals Llc |
Kompozycja farmaceutyczna
|
TW200817048A
(en)
*
|
2006-09-08 |
2008-04-16 |
Wyeth Corp |
Dry powder compound formulations and uses thereof
|
WO2008033124A1
(en)
*
|
2006-09-13 |
2008-03-20 |
The Procter & Gamble Company |
Methods of treatment for ulcerative colitis
|
AU2006348138A1
(en)
*
|
2006-09-13 |
2008-03-20 |
Warner Chilcott Company, Llc |
Methods of treatment for ulcerative colitis using aminosalicylate
|
TWI466671B
(zh)
|
2007-03-29 |
2015-01-01 |
Progenics Pharm Inc |
末梢性類鴉片受體拮抗劑及其用途
|
EP3263571B2
(en)
|
2007-03-29 |
2023-08-23 |
Progenics Pharmaceuticals, Inc. |
Crystal form of (r)-n-methylnaltrexone bromide and uses thereof
|
MX2009010515A
(es)
|
2007-03-29 |
2009-10-19 |
Wyeth Corp |
Antagonistas del receptor opioide periferico y usos de los mismos.
|
AU2008261102B2
(en)
|
2007-06-04 |
2013-11-28 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
EP2214672B1
(en)
*
|
2007-10-18 |
2012-10-17 |
Aiko Biotechnology |
Combination analgesic employing opioid and neutral antagonist
|
US8748448B2
(en)
|
2007-10-18 |
2014-06-10 |
Aiko Biotechnology |
Combination analgesic employing opioid agonist and neutral antagonist
|
US20090130063A1
(en)
*
|
2007-11-15 |
2009-05-21 |
Solvay Pharmaceuticals Gmbh |
Process for separating and determining the viral load in a pancreatin sample
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
CN101959892B
(zh)
|
2008-02-06 |
2014-01-08 |
普罗热尼奇制药公司 |
(r),(r)-2,2’-二-甲基纳曲酮的制备和用途
|
EP2278966B1
(en)
|
2008-03-21 |
2019-10-09 |
The University of Chicago |
Treatment with opioid antagonists and mtor inhibitors
|
MX2010011727A
(es)
*
|
2008-05-07 |
2010-11-30 |
Nektar Therapeutics |
Administracion oral de antagonistas opioides que actuan perifericamente.
|
WO2009149279A2
(en)
|
2008-06-04 |
2009-12-10 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
EP3241839B1
(en)
|
2008-07-16 |
2019-09-04 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
CA2676881C
(en)
|
2008-09-30 |
2017-04-25 |
Wyeth |
Peripheral opioid receptor antagonists and uses thereof
|
CA2748607A1
(en)
|
2008-12-31 |
2010-07-08 |
Ardelyx, Inc. |
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
WO2018129556A1
(en)
|
2017-01-09 |
2018-07-12 |
Ardelyx, Inc. |
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
SG174286A1
(en)
|
2009-03-10 |
2011-10-28 |
Euro Celtique Sa |
Immediate release pharmaceutical compositions comprising oxycodone and naloxone
|
EA201171271A1
(ru)
*
|
2009-04-22 |
2012-05-30 |
Фоеме Гмбх |
Фармацевтическая композиция в форме частиц с опиоидом и антагонистом опиоида
|
KR20120092592A
(ko)
*
|
2009-09-18 |
2012-08-21 |
아돌로 코포레이션 |
위장관 질환을 위한 오피오이드 수용체 길항제의 용도
|
WO2011141490A1
(en)
|
2010-05-10 |
2011-11-17 |
Euro-Celtique S.A. |
Combination of active loaded granules with additional actives
|
CN103002882B
(zh)
|
2010-05-10 |
2016-03-02 |
欧洲凯尔特公司 |
不含活性剂之颗粒及包含其之片剂的制备
|
US10376481B2
(en)
|
2012-08-21 |
2019-08-13 |
Ardelyx, Inc. |
Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
AU2013304812B2
(en)
|
2012-08-21 |
2016-06-09 |
Ardelyx, Inc. |
Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
WO2014032108A1
(en)
*
|
2012-08-29 |
2014-03-06 |
Borody Thomas J |
Laxative compositions and methods for treating constipation and related gastrointestinal diseases and conditions
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
AU2014235209B2
(en)
|
2013-03-15 |
2018-06-14 |
Bausch Health Ireland Limited |
Guanylate cyclase receptor agonists combined with other drugs
|
PT2983667T
(pt)
|
2013-04-12 |
2019-07-11 |
Ardelyx Inc |
Compostos e métodos de ligação ao nhe3 para inibir o transporte de fosfato
|
WO2015011189A1
(en)
|
2013-07-23 |
2015-01-29 |
Euro-Celtique S.A. |
A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
|
CN105916505A
(zh)
|
2013-11-13 |
2016-08-31 |
欧洲凯尔特公司 |
用于治疗疼痛和阿片样物质肠功能障碍综合征的氢吗啡酮和纳洛酮
|
CN107205943A
(zh)
*
|
2014-12-08 |
2017-09-26 |
德威洛克制药有限公司 |
纳洛酮单剂和多层片剂
|
US20160256451A1
(en)
*
|
2015-03-06 |
2016-09-08 |
Develco Pharma Schweiz Ag |
Dosage of naloxone
|
WO2016193456A2
(en)
*
|
2015-06-03 |
2016-12-08 |
Develco Pharma Schweiz Ag |
Opioid receptor antagonist for use in treating patients with severe constipation
|
US9943513B1
(en)
|
2015-10-07 |
2018-04-17 |
Banner Life Sciences Llc |
Opioid abuse deterrent dosage forms
|
US10335405B1
(en)
|
2016-05-04 |
2019-07-02 |
Patheon Softgels, Inc. |
Non-burst releasing pharmaceutical composition
|
BR112019013963A2
(pt)
|
2017-01-09 |
2020-04-28 |
Ardelyx Inc |
inibidores de antiporte mediado por nhe
|
US11242337B2
(en)
|
2017-01-09 |
2022-02-08 |
Ardelyx, Inc. |
Compounds useful for treating gastrointestinal tract disorders
|
US10335375B2
(en)
|
2017-05-30 |
2019-07-02 |
Patheon Softgels, Inc. |
Anti-overingestion abuse deterrent compositions
|
WO2023102491A1
(en)
*
|
2021-12-01 |
2023-06-08 |
Invea Therapeutics, Inc. |
Methods for treating gastrointestinal inflammatory disease
|