JP2002542159A - メラノコルチン受容体リガンド - Google Patents
メラノコルチン受容体リガンドInfo
- Publication number
- JP2002542159A JP2002542159A JP2000608653A JP2000608653A JP2002542159A JP 2002542159 A JP2002542159 A JP 2002542159A JP 2000608653 A JP2000608653 A JP 2000608653A JP 2000608653 A JP2000608653 A JP 2000608653A JP 2002542159 A JP2002542159 A JP 2002542159A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- heteroaryl
- aryl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12667399P | 1999-03-29 | 1999-03-29 | |
| US60/126,673 | 1999-03-29 | ||
| PCT/US2000/007473 WO2000058361A1 (en) | 1999-03-29 | 2000-03-21 | Melanocortin receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002542159A true JP2002542159A (ja) | 2002-12-10 |
Family
ID=22426131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000608653A Pending JP2002542159A (ja) | 1999-03-29 | 2000-03-21 | メラノコルチン受容体リガンド |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US6613874B1 (zh) |
| EP (1) | EP1165613B1 (zh) |
| JP (1) | JP2002542159A (zh) |
| KR (2) | KR100519201B1 (zh) |
| CN (1) | CN1249086C (zh) |
| AR (1) | AR023201A1 (zh) |
| AT (1) | ATE393783T1 (zh) |
| AU (1) | AU763510B2 (zh) |
| BR (1) | BR0009497A (zh) |
| CA (1) | CA2368431C (zh) |
| CO (1) | CO5170531A1 (zh) |
| CZ (1) | CZ20013407A3 (zh) |
| DE (1) | DE60038734T2 (zh) |
| DK (1) | DK1165613T3 (zh) |
| ES (1) | ES2304345T3 (zh) |
| HK (1) | HK1044954B (zh) |
| HU (1) | HUP0202203A3 (zh) |
| ID (1) | ID30262A (zh) |
| IL (1) | IL145406A0 (zh) |
| MA (1) | MA25403A1 (zh) |
| MX (1) | MXPA01009881A (zh) |
| MY (1) | MY126585A (zh) |
| NO (1) | NO20014568L (zh) |
| NZ (1) | NZ514141A (zh) |
| PE (1) | PE20001641A1 (zh) |
| PL (1) | PL350095A1 (zh) |
| PT (1) | PT1165613E (zh) |
| RU (1) | RU2213098C2 (zh) |
| SA (1) | SA00210192B1 (zh) |
| SK (1) | SK13082001A3 (zh) |
| TR (1) | TR200102765T2 (zh) |
| TW (1) | TWI250990B (zh) |
| WO (1) | WO2000058361A1 (zh) |
| ZA (1) | ZA200107411B (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007532471A (ja) * | 2003-09-30 | 2007-11-15 | ノボ ノルディスク アクティーゼルスカブ | 新規メラノコルチンレセプターアゴニスト |
| JP2013510881A (ja) * | 2009-11-16 | 2013-03-28 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | Ａｃ−Ａｒｇ−シクロ（Ｃｙｓ−Ｄ−Ａｌａ−Ｈｉｓ−Ｄ−Ｐｈｅ−Ａｒｇ−Ｔｒｐ−Ｃｙｓ）−ＮＨ２の合成のための方法 |
Families Citing this family (71)
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| US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
| CA2377369A1 (en) | 1999-06-04 | 2000-12-14 | Merck & Co., Inc. | Substituted piperidines as melanocortin-4 receptor agonists |
| US7235625B2 (en) | 1999-06-29 | 2007-06-26 | Palatin Technologies, Inc. | Multiple agent therapy for sexual dysfunction |
| EP1251865A1 (en) * | 2000-01-18 | 2002-10-30 | Merck & Co., Inc. | Cyclic peptides as potent and selective melanocortin-4 receptor antagonists |
| ES2280393T3 (es) | 2000-08-30 | 2007-09-16 | F. Hoffmann-La Roche Ag | Peptidos ciclicos que tienen actividad agonista para el receptor de melanocortin-4. |
| AU2001296313B2 (en) * | 2000-09-27 | 2005-06-02 | The Procter & Gamble Company | Melanocortin receptor ligands |
| AU2002238106A1 (en) | 2001-02-13 | 2002-08-28 | Palatin Technologies, Inc. | Melanocortin metallopeptides for treatment of sexual dysfunction |
| US7345144B2 (en) * | 2001-07-11 | 2008-03-18 | Palatin Technologies, Inc. | Cyclic peptides for treatment of cachexia |
| IL159797A0 (en) | 2001-07-11 | 2004-06-20 | Palatin Technologies Inc | Linear and cyclic melanocortin receptor-specific peptides |
| US7342089B2 (en) * | 2001-07-11 | 2008-03-11 | Palatin Technologies, Inc. | Cyclic peptides for treatment for cachexia |
| US20030195187A1 (en) * | 2002-02-04 | 2003-10-16 | Chiron Corporation | Guanidino compounds |
| US7034004B2 (en) * | 2002-05-07 | 2006-04-25 | University Of Florida | Peptides and methods for the control of obesity |
| US7323462B2 (en) | 2002-12-10 | 2008-01-29 | Pfizer Inc. | Morpholine dopamine agonists |
| CA2530024A1 (en) * | 2003-06-19 | 2005-01-06 | Eli Lilly And Company | Melanocortin receptor 4(mc4) agonists and their uses |
| WO2005000338A1 (en) * | 2003-06-19 | 2005-01-06 | Eli Lilly And Company | Uses of melanocortin-3 receptor (mc3r) agonist peptides |
| AU2015201062B2 (en) * | 2003-11-05 | 2017-03-09 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| ES2437567T3 (es) * | 2003-11-05 | 2014-01-13 | Dana-Farber Cancer Institute, Inc. | Péptidos alfa helicoidales estabilizados y utilizaciones de los mismos |
| DK2842576T3 (en) | 2004-01-21 | 2017-10-16 | Novo Nordisk Healthcare Ag | Transglutaminase-mediated peptide conjugation |
| US6974187B2 (en) * | 2004-01-28 | 2005-12-13 | Tachi-S Co., Ltd. | Vehicle seat structure |
| EP1732586A1 (en) * | 2004-03-29 | 2006-12-20 | Eli Lilly And Company | Uses of melanocortin-4 receptor (mc4r) agonist peptides administered by continunous infusion |
| WO2006041769A2 (en) * | 2004-10-05 | 2006-04-20 | Merck & Co., Inc. | Methods for the treatment of substance abuse and addiction |
| WO2006060873A1 (en) * | 2004-12-09 | 2006-06-15 | Prince Henry's Institute Of Medical Research | Method for restoring reproductive function |
| WO2006073772A1 (en) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Polyethylene glycol linked mc4r or mc3r agonist peptides |
| WO2006073771A2 (en) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Polyethylene glycol linked mc4r or mc3r agonist peptides |
| US20070021433A1 (en) | 2005-06-03 | 2007-01-25 | Jian-Qiang Fan | Pharmacological chaperones for treating obesity |
| US7754691B1 (en) | 2005-07-07 | 2010-07-13 | Palatin Technologies, Inc. | Linear melanocortin receptor-specific peptides for cachexia |
| PT2236151E (pt) * | 2005-07-08 | 2012-07-02 | Ipsen Pharma | Ligandos do receptor de melanocortina |
| EP1915168A4 (en) * | 2005-07-08 | 2010-03-31 | Ipsen Pharma | LIGANDS OF MELANOCORTIN RECEPTORS |
| EP1968995A1 (en) * | 2005-12-30 | 2008-09-17 | F. Hoffmann-la Roche AG | Methods for the synthesis of arginine-containing peptides |
| MX2008015454A (es) | 2006-06-09 | 2009-01-30 | Action Pharma As | Derivados de fenil-pirrol-aminoguanidina. |
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| BRPI1006139A2 (pt) | 2009-01-14 | 2017-05-30 | Aileron Therapeutics Inc | macrociclos peptidomiméticos |
| JP5805632B2 (ja) | 2009-06-08 | 2015-11-04 | パラティン テクノロジーズ, インコーポレイテッドPalatin Technologies, Inc. | メラノコルチン受容体に特異的なペプチド |
| EP2440572B1 (en) | 2009-06-08 | 2017-04-05 | Palatin Technologies, Inc. | Lactam-bridged melanocortin receptor-specific peptides |
| UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| US9163330B2 (en) | 2009-07-13 | 2015-10-20 | President And Fellows Of Harvard College | Bifunctional stapled polypeptides and uses thereof |
| JP2013505300A (ja) | 2009-09-22 | 2013-02-14 | エルロン・セラピューティクス・インコーポレイテッド | ペプチド模倣大環状分子 |
| BR112012011787B1 (pt) | 2009-11-23 | 2022-03-03 | Palatin Technologies, Inc | Peptídeo cíclico e composição farmacêutica |
| EA201290295A1 (ru) | 2009-11-23 | 2013-01-30 | Палатин Текнолоджиз, Инк. | Специфичные к рецептору меланокортина-1 линейные пептиды |
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| US8957026B2 (en) | 2010-09-22 | 2015-02-17 | President And Fellows Of Harvard College | Beta-catenin targeting peptides and uses thereof |
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| US11932628B2 (en) | 2021-01-04 | 2024-03-19 | Regents Of The University Of Minnesota | Selective small molecule peptidomimetic melanocortin ligands |
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| US5462927A (en) | 1985-04-30 | 1995-10-31 | The Administrators Of The Tulane Educational Fund | Peptides aiding nerve regeneration |
| ATE109793T1 (de) | 1987-05-22 | 1994-08-15 | University Patents Inc | Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung. |
| WO1989002897A1 (en) | 1987-09-24 | 1989-04-06 | The Administrators Of The Tulane Educational Fund | Therapeutic peptides |
| ZA908610B (en) | 1989-11-03 | 1991-08-28 | Univ Tulane | Peptides aiding nerve regeneration |
| ATE140236T1 (de) | 1991-02-15 | 1996-07-15 | Takeda Chemical Industries Ltd | Endothelin antagoniste |
| ES2103857T3 (es) | 1991-08-13 | 1997-10-01 | Takeda Chemical Industries Ltd | Peptidos ciclicos y su uso. |
| ES2133295T3 (es) | 1991-11-19 | 1999-09-16 | Takeda Chemical Industries Ltd | Peptidos ciclicos y su uso. |
| EP0547317A1 (en) | 1991-12-19 | 1993-06-23 | Takeda Chemical Industries, Ltd. | Endothelin antagonists |
| DE9203901U1 (de) | 1992-03-24 | 1992-07-16 | Croon & Lucke Maschinenfabrik Gmbh, 7947 Mengen | Gestell zum Lagern von flächigen Werkstücken |
| DK0606463T3 (da) | 1992-07-27 | 2001-12-03 | Univ Tulane | Antagonister for neuromedin-B-receptor |
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| AU673731B2 (en) | 1993-06-03 | 1996-11-21 | Banyu Pharmaceutical Co., Ltd. | Novel endothelin antagonistic peptide |
| EP0714909A1 (en) | 1994-12-01 | 1996-06-05 | Takeda Chemical Industries, Ltd. | Composition for prophylaxis or treatment of pulmonary circulatory diseases |
| US5731408A (en) * | 1995-04-10 | 1998-03-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Peptides having potent antagonist and agonist bioactivities at melanocortin receptors |
| US6054556A (en) * | 1995-04-10 | 2000-04-25 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Melanocortin receptor antagonists and agonists |
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| US5817750A (en) | 1995-08-28 | 1998-10-06 | La Jolla Cancer Research Foundation | Structural mimics of RGD-binding sites |
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| EP0815870A3 (en) | 1996-06-27 | 2000-05-03 | Takeda Chemical Industries, Ltd. | Composition for prohylaxis or treatment of cerebral infarction |
| US5770380A (en) | 1996-09-13 | 1998-06-23 | University Of Pittsburgh | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold |
| IT1288388B1 (it) | 1996-11-19 | 1998-09-22 | Angeletti P Ist Richerche Bio | Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia |
| AU5348098A (en) | 1996-12-17 | 1998-07-15 | Quadrant Holdings Cambridge Limited | Melanocortins |
| SE9700620D0 (sv) * | 1997-02-21 | 1997-02-21 | Wapharm Ab | Cykliska peptider med selektivitet för MSH-receptor subtyper |
| GB9827500D0 (en) | 1998-12-14 | 1999-02-10 | Wapharm Ab | Compounds for control of eating, growth and body weight |
-
2000
- 2000-03-21 CN CNB008057540A patent/CN1249086C/zh not_active Expired - Fee Related
- 2000-03-21 CZ CZ20013407A patent/CZ20013407A3/cs unknown
- 2000-03-21 JP JP2000608653A patent/JP2002542159A/ja active Pending
- 2000-03-21 IL IL14540600A patent/IL145406A0/xx unknown
- 2000-03-21 EP EP00919500A patent/EP1165613B1/en not_active Expired - Lifetime
- 2000-03-21 DE DE60038734T patent/DE60038734T2/de not_active Expired - Fee Related
- 2000-03-21 PL PL00350095A patent/PL350095A1/xx not_active Application Discontinuation
- 2000-03-21 WO PCT/US2000/007473 patent/WO2000058361A1/en not_active Application Discontinuation
- 2000-03-21 KR KR10-2001-7012436A patent/KR100519201B1/ko not_active IP Right Cessation
- 2000-03-21 AU AU40179/00A patent/AU763510B2/en not_active Ceased
- 2000-03-21 AT AT00919500T patent/ATE393783T1/de not_active IP Right Cessation
- 2000-03-21 ES ES00919500T patent/ES2304345T3/es not_active Expired - Lifetime
- 2000-03-21 CA CA002368431A patent/CA2368431C/en not_active Expired - Fee Related
- 2000-03-21 NZ NZ514141A patent/NZ514141A/xx unknown
- 2000-03-21 HU HU0202203A patent/HUP0202203A3/hu unknown
- 2000-03-21 SK SK1308-2001A patent/SK13082001A3/sk unknown
- 2000-03-21 TR TR2001/02765T patent/TR200102765T2/xx unknown
- 2000-03-21 MX MXPA01009881A patent/MXPA01009881A/es active IP Right Grant
- 2000-03-21 DK DK00919500T patent/DK1165613T3/da active
- 2000-03-21 PT PT00919500T patent/PT1165613E/pt unknown
- 2000-03-21 KR KR1020047019303A patent/KR100558131B1/ko not_active IP Right Cessation
- 2000-03-21 RU RU2001128890/04A patent/RU2213098C2/ru not_active IP Right Cessation
- 2000-03-21 ID IDW00200102111A patent/ID30262A/id unknown
- 2000-03-21 BR BR0009497-8A patent/BR0009497A/pt not_active IP Right Cessation
- 2000-03-27 MY MYPI20001220A patent/MY126585A/en unknown
- 2000-03-28 CO CO00022068A patent/CO5170531A1/es not_active Application Discontinuation
- 2000-03-28 TW TW089105726A patent/TWI250990B/zh not_active IP Right Cessation
- 2000-03-29 AR ARP000101405A patent/AR023201A1/es active IP Right Grant
- 2000-03-29 US US09/537,789 patent/US6613874B1/en not_active Expired - Fee Related
- 2000-03-29 PE PE2000000267A patent/PE20001641A1/es not_active Application Discontinuation
- 2000-06-26 SA SA00210192A patent/SA00210192B1/ar unknown
-
2001
- 2001-09-07 ZA ZA200107411A patent/ZA200107411B/xx unknown
- 2001-09-20 NO NO20014568A patent/NO20014568L/no not_active Application Discontinuation
- 2001-09-26 MA MA26340A patent/MA25403A1/fr unknown
-
2002
- 2002-06-24 HK HK02104687.8A patent/HK1044954B/zh not_active IP Right Cessation
-
2003
- 2003-07-02 US US10/612,104 patent/US6951916B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007532471A (ja) * | 2003-09-30 | 2007-11-15 | ノボ ノルディスク アクティーゼルスカブ | 新規メラノコルチンレセプターアゴニスト |
| JP2013510881A (ja) * | 2009-11-16 | 2013-03-28 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | Ａｃ−Ａｒｇ−シクロ（Ｃｙｓ−Ｄ−Ａｌａ−Ｈｉｓ−Ｄ−Ｐｈｅ−Ａｒｇ−Ｔｒｐ−Ｃｙｓ）−ＮＨ２の合成のための方法 |
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