JP2002541818A - 高感度ファージ提示生体分子検出 - Google Patents
高感度ファージ提示生体分子検出Info
- Publication number
- JP2002541818A JP2002541818A JP2000611713A JP2000611713A JP2002541818A JP 2002541818 A JP2002541818 A JP 2002541818A JP 2000611713 A JP2000611713 A JP 2000611713A JP 2000611713 A JP2000611713 A JP 2000611713A JP 2002541818 A JP2002541818 A JP 2002541818A
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
Landscapes
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- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US60/129,215 | 1999-04-14 | ||
| PCT/US2000/010146 WO2000061790A1 (en) | 1999-04-14 | 2000-04-13 | High sensitivity phage display biomolecule detection |
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| JP2002541818A true JP2002541818A (ja) | 2002-12-10 |
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| WO2003010198A1 (en) * | 2001-07-26 | 2003-02-06 | Kenton Srl | Identification of specific tumour antigens by selection of cdna libraries with sera and use of said antigens in diagnostic techniques |
| WO2003011902A1 (en) * | 2001-07-27 | 2003-02-13 | Kenton S.R.L. | Identification of specific tumour antigens by selection of cdna libraries with sera |
| AU2003272491B2 (en) * | 2002-09-18 | 2008-10-02 | The Trustees Of The University Of Pennsylvania | Compositions, methods and kits for detection of an antigen on a cell and in a biological mixture |
| GB0304832D0 (en) * | 2003-03-04 | 2003-04-09 | Secr Defence | Assay method |
| JP5214979B2 (ja) * | 2005-02-24 | 2013-06-19 | ライフ テクノロジーズ コーポレーション | エレクトロブロッティング装置、システム及びキット、並びにそれらの使用方法 |
| US20080193917A1 (en) | 2005-05-27 | 2008-08-14 | David Alexander Schofield | Biological Detection System and Method |
| US8066866B2 (en) * | 2005-10-17 | 2011-11-29 | Lifescan, Inc. | Methods for measuring physiological fluids |
| WO2007064462A1 (en) * | 2005-11-29 | 2007-06-07 | The Trustees Of The University Of Pennsylvania | Phage particle diagnostic reagents |
| WO2010006318A2 (en) * | 2008-07-11 | 2010-01-14 | Life Technologies Corporation | Electrophoretically enhanced detection of analytes on a solid support |
| USD738527S1 (en) | 2013-05-28 | 2015-09-08 | Life Technologies Corporation | Electroblotting apparatus |
| TWI570243B (zh) * | 2015-11-03 | 2017-02-11 | 國立清華大學 | 噬菌體之篩選裝置及方法 |
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| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| GB9104411D0 (en) * | 1991-03-01 | 1991-04-17 | Elchrom Limited | Improvement of gel composition in gels for submerged gel electrophoresis |
| BE1006312A3 (fr) * | 1991-11-29 | 1994-07-19 | Univ Catholique Louvain | Procede de selection de microorganismes recombinants comportant a leur surface au moins une molecule a activite enzymatique. |
| US5679510A (en) * | 1993-04-27 | 1997-10-21 | Hybridon, Inc. | Quantitative detection of specific nucleic acid sequences using lambdoid bacteriophages linked by oligonucleotides to solid support |
| US5650267A (en) * | 1993-04-27 | 1997-07-22 | Symbiotech, Inc. | Method of detecting compounds utilizing genetically modified lambdoid bacteriophage |
| US6027877A (en) * | 1993-11-04 | 2000-02-22 | Gene Check, Inc. | Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification |
| US5702892A (en) * | 1995-05-09 | 1997-12-30 | The United States Of America As Represented By The Department Of Health And Human Services | Phage-display of immunoglobulin heavy chain libraries |
| IL114149A0 (en) * | 1995-06-14 | 1995-10-31 | Yeda Res & Dev | Modified avidin and streptavidin molecules and use thereof |
| JP2000502896A (ja) * | 1995-12-15 | 2000-03-14 | ファルマシア・アンド・アップジョン・カンパニー | 病気の状態に対する治療標的およびその中和抗体様分子の同時検出法 |
| DE69718341T2 (de) * | 1996-10-08 | 2003-10-30 | U-Bisys B.V., Utrecht | Verfahren und mittel zur auswahl von peptiden und proteinen mit spezifischer affinität zu einem zielmolekül |
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| AU778776B2 (en) | 2004-12-23 |
| US20020110806A1 (en) | 2002-08-15 |
| WO2000061790A1 (en) | 2000-10-19 |
| ATE346162T1 (de) | 2006-12-15 |
| CA2368875A1 (en) | 2000-10-19 |
| DE60031965D1 (de) | 2007-01-04 |
| EP1169473A1 (en) | 2002-01-09 |
| US6740492B2 (en) | 2004-05-25 |
| AU4461200A (en) | 2000-11-14 |
| EP1169473B1 (en) | 2006-11-22 |
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