JP2004505649A5 - - Google Patents
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- JP2004505649A5 JP2004505649A5 JP2002519613A JP2002519613A JP2004505649A5 JP 2004505649 A5 JP2004505649 A5 JP 2004505649A5 JP 2002519613 A JP2002519613 A JP 2002519613A JP 2002519613 A JP2002519613 A JP 2002519613A JP 2004505649 A5 JP2004505649 A5 JP 2004505649A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- nucleic acid
- substance
- acid sequence
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 108090000623 proteins and genes Proteins 0.000 description 35
- 102000004169 proteins and genes Human genes 0.000 description 35
- 150000007523 nucleic acids Chemical group 0.000 description 27
- 108020004707 nucleic acids Proteins 0.000 description 17
- 102000039446 nucleic acids Human genes 0.000 description 17
- 238000000034 method Methods 0.000 description 16
- 239000000126 substance Substances 0.000 description 14
- 108091028043 Nucleic acid sequence Proteins 0.000 description 9
- 101000605518 Homo sapiens Kallikrein-15 Proteins 0.000 description 8
- 102100038301 Kallikrein-15 Human genes 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 7
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 239000012472 biological sample Substances 0.000 description 5
- 238000009396 hybridization Methods 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000009918 complex formation Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- 108020004705 Codon Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000007876 drug discovery Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000003752 polymerase chain reaction Methods 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000006916 protein interaction Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22485300P | 2000-08-11 | 2000-08-11 | |
| PCT/CA2001/001141 WO2002014485A2 (en) | 2000-08-11 | 2001-08-10 | Kallikrein gene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004505649A JP2004505649A (ja) | 2004-02-26 |
| JP2004505649A5 true JP2004505649A5 (cg-RX-API-DMAC7.html) | 2008-10-02 |
Family
ID=22842508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002519613A Pending JP2004505649A (ja) | 2000-08-11 | 2001-08-10 | 新規なカリクレイン遺伝子 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7199229B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1309703B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2004505649A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE330017T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU8738401A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2418422C (cg-RX-API-DMAC7.html) |
| DE (1) | DE60120712T2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2266245T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002014485A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| US9012141B2 (en) * | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| AU8738401A (en) | 2000-08-11 | 2002-02-25 | Mount Sinai Hospital Corp | Novel kallikrein gene |
| CA2426286A1 (en) * | 2000-10-27 | 2002-05-02 | Mount Sinai Hospital | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
| EP1332367A2 (en) * | 2000-11-01 | 2003-08-06 | Mount Sinai Hospital | Detection of ovarian cancer |
| CA2448355A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| US20050176002A1 (en) * | 2001-10-16 | 2005-08-11 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| AU2003266038A1 (en) * | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| US20060073525A1 (en) * | 2002-08-28 | 2006-04-06 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| EP1546728A2 (en) * | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| CA2516591A1 (en) * | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| WO2004077060A2 (en) * | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| US20050106586A1 (en) * | 2003-06-13 | 2005-05-19 | Mount Sinai Hospital | Detection of neurodegenerative diseases |
| US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
| WO2005075664A1 (en) * | 2004-01-28 | 2005-08-18 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with kallikrein 15 (klk15) |
| DK2853269T3 (da) | 2008-05-19 | 2019-08-05 | Advaxis Inc | Dobbelt indgivelsessystem til heterologe antigener, der omfatter en rekombinant Listeria-stamme svækket ved mutation af dal/dat og deletion af ActA, der omfatter et nukleinsyremolekyle, der koder for et listeriolysin O-prostataspecifikt antigenfusionsprotein |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| CN107412756A (zh) | 2010-10-01 | 2017-12-01 | 宾夕法尼亚大学理事会 | 李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途 |
| CN103687611A (zh) | 2011-03-11 | 2014-03-26 | 阿德瓦希斯公司 | 基于李斯特菌属的佐剂 |
| US10058599B2 (en) | 2012-03-12 | 2018-08-28 | Advaxis, Inc. | Suppressor cell function inhibition following Listeria vaccine treatment |
| GB201513921D0 (en) * | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022497B1 (en) | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| AU2001271427A1 (en) * | 2000-06-26 | 2002-01-08 | Sugen, Inc. | Novel proteases |
| WO2002008396A2 (en) * | 2000-07-21 | 2002-01-31 | Incyte Genomics, Inc. | Human proteases |
| AU8738401A (en) | 2000-08-11 | 2002-02-25 | Mount Sinai Hospital Corp | Novel kallikrein gene |
| CA2360219A1 (en) * | 2000-10-27 | 2002-04-27 | Mount Sinai Hospital | Method for detecting alzheimer's disease |
| CA2426286A1 (en) * | 2000-10-27 | 2002-05-02 | Mount Sinai Hospital | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
| EP1332367A2 (en) * | 2000-11-01 | 2003-08-06 | Mount Sinai Hospital | Detection of ovarian cancer |
| CA2448355A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| US20050176002A1 (en) * | 2001-10-16 | 2005-08-11 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| CA2481093A1 (en) | 2002-04-04 | 2003-10-16 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| US20060073525A1 (en) | 2002-08-28 | 2006-04-06 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| AU2003266038A1 (en) | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| EP1546728A2 (en) | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| CA2516591A1 (en) | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| WO2004077060A2 (en) | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| US20050106586A1 (en) | 2003-06-13 | 2005-05-19 | Mount Sinai Hospital | Detection of neurodegenerative diseases |
| US20060269971A1 (en) | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
-
2001
- 2001-08-10 AU AU8738401A patent/AU8738401A/xx active Pending
- 2001-08-10 EP EP01966837A patent/EP1309703B1/en not_active Expired - Lifetime
- 2001-08-10 DE DE60120712T patent/DE60120712T2/de not_active Expired - Lifetime
- 2001-08-10 JP JP2002519613A patent/JP2004505649A/ja active Pending
- 2001-08-10 WO PCT/CA2001/001141 patent/WO2002014485A2/en not_active Ceased
- 2001-08-10 ES ES01966837T patent/ES2266245T3/es not_active Expired - Lifetime
- 2001-08-10 AT AT01966837T patent/ATE330017T1/de not_active IP Right Cessation
- 2001-08-10 US US10/344,394 patent/US7199229B2/en not_active Expired - Fee Related
- 2001-08-10 AU AU2001287384A patent/AU2001287384B2/en not_active Ceased
- 2001-08-10 CA CA2418422A patent/CA2418422C/en not_active Expired - Fee Related
-
2007
- 2007-03-29 US US11/729,560 patent/US7507403B2/en not_active Expired - Fee Related
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