DE60120712T2 - Kallikrein gen - Google Patents
Kallikrein gen Download PDFInfo
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- DE60120712T2 DE60120712T2 DE60120712T DE60120712T DE60120712T2 DE 60120712 T2 DE60120712 T2 DE 60120712T2 DE 60120712 T DE60120712 T DE 60120712T DE 60120712 T DE60120712 T DE 60120712T DE 60120712 T2 DE60120712 T2 DE 60120712T2
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- klk15
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
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- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21034—Plasma kallikrein (3.4.21.34)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
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| US224853P | 2000-08-11 | ||
| PCT/CA2001/001141 WO2002014485A2 (en) | 2000-08-11 | 2001-08-10 | Kallikrein gene |
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|---|---|
| DE60120712D1 DE60120712D1 (en) | 2006-07-27 |
| DE60120712T2 true DE60120712T2 (de) | 2007-07-19 |
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| DE60120712T Expired - Lifetime DE60120712T2 (de) | 2000-08-11 | 2001-08-10 | Kallikrein gen |
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| ES (1) | ES2266245T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002014485A2 (cg-RX-API-DMAC7.html) |
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| US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| US9012141B2 (en) * | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| AU8738401A (en) | 2000-08-11 | 2002-02-25 | Mount Sinai Hospital Corp | Novel kallikrein gene |
| CA2426286A1 (en) * | 2000-10-27 | 2002-05-02 | Mount Sinai Hospital | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
| EP1332367A2 (en) * | 2000-11-01 | 2003-08-06 | Mount Sinai Hospital | Detection of ovarian cancer |
| CA2448355A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| US20050176002A1 (en) * | 2001-10-16 | 2005-08-11 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| AU2003266038A1 (en) * | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| US20060073525A1 (en) * | 2002-08-28 | 2006-04-06 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| EP1546728A2 (en) * | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| CA2516591A1 (en) * | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| WO2004077060A2 (en) * | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| US20050106586A1 (en) * | 2003-06-13 | 2005-05-19 | Mount Sinai Hospital | Detection of neurodegenerative diseases |
| US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
| WO2005075664A1 (en) * | 2004-01-28 | 2005-08-18 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with kallikrein 15 (klk15) |
| DK2853269T3 (da) | 2008-05-19 | 2019-08-05 | Advaxis Inc | Dobbelt indgivelsessystem til heterologe antigener, der omfatter en rekombinant Listeria-stamme svækket ved mutation af dal/dat og deletion af ActA, der omfatter et nukleinsyremolekyle, der koder for et listeriolysin O-prostataspecifikt antigenfusionsprotein |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| CN107412756A (zh) | 2010-10-01 | 2017-12-01 | 宾夕法尼亚大学理事会 | 李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途 |
| CN103687611A (zh) | 2011-03-11 | 2014-03-26 | 阿德瓦希斯公司 | 基于李斯特菌属的佐剂 |
| US10058599B2 (en) | 2012-03-12 | 2018-08-28 | Advaxis, Inc. | Suppressor cell function inhibition following Listeria vaccine treatment |
| GB201513921D0 (en) * | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
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| US7022497B1 (en) | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| AU2001271427A1 (en) * | 2000-06-26 | 2002-01-08 | Sugen, Inc. | Novel proteases |
| WO2002008396A2 (en) * | 2000-07-21 | 2002-01-31 | Incyte Genomics, Inc. | Human proteases |
| AU8738401A (en) | 2000-08-11 | 2002-02-25 | Mount Sinai Hospital Corp | Novel kallikrein gene |
| CA2360219A1 (en) * | 2000-10-27 | 2002-04-27 | Mount Sinai Hospital | Method for detecting alzheimer's disease |
| CA2426286A1 (en) * | 2000-10-27 | 2002-05-02 | Mount Sinai Hospital | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
| EP1332367A2 (en) * | 2000-11-01 | 2003-08-06 | Mount Sinai Hospital | Detection of ovarian cancer |
| CA2448355A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| US20050176002A1 (en) * | 2001-10-16 | 2005-08-11 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| CA2481093A1 (en) | 2002-04-04 | 2003-10-16 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| US20060073525A1 (en) | 2002-08-28 | 2006-04-06 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| AU2003266038A1 (en) | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| EP1546728A2 (en) | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| CA2516591A1 (en) | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| WO2004077060A2 (en) | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| US20050106586A1 (en) | 2003-06-13 | 2005-05-19 | Mount Sinai Hospital | Detection of neurodegenerative diseases |
| US20060269971A1 (en) | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
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2001
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- 2001-08-10 ES ES01966837T patent/ES2266245T3/es not_active Expired - Lifetime
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- 2001-08-10 US US10/344,394 patent/US7199229B2/en not_active Expired - Fee Related
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Also Published As
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| ES2266245T3 (es) | 2007-03-01 |
| ATE330017T1 (de) | 2006-07-15 |
| US20040058342A1 (en) | 2004-03-25 |
| EP1309703A2 (en) | 2003-05-14 |
| US20070178114A1 (en) | 2007-08-02 |
| JP2004505649A (ja) | 2004-02-26 |
| WO2002014485A2 (en) | 2002-02-21 |
| EP1309703B1 (en) | 2006-06-14 |
| WO2002014485A3 (en) | 2003-01-09 |
| DE60120712D1 (en) | 2006-07-27 |
| US7199229B2 (en) | 2007-04-03 |
| CA2418422C (en) | 2011-06-07 |
| CA2418422A1 (en) | 2002-02-21 |
| AU8738401A (en) | 2002-02-25 |
| US7507403B2 (en) | 2009-03-24 |
| AU2001287384B2 (en) | 2007-03-29 |
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