JP2002540168A - 多価デングウイルスワクチン - Google Patents

多価デングウイルスワクチン

Info

Publication number
JP2002540168A
JP2002540168A JP2000607657A JP2000607657A JP2002540168A JP 2002540168 A JP2002540168 A JP 2002540168A JP 2000607657 A JP2000607657 A JP 2000607657A JP 2000607657 A JP2000607657 A JP 2000607657A JP 2002540168 A JP2002540168 A JP 2002540168A
Authority
JP
Japan
Prior art keywords
dengue
virus
vaccine
cells
response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000607657A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002540168A5 (https=
Inventor
ケネス, エイチ. エッケルス,
ジョゼフ, アール. プトナク,
ドリア, アール. デュボイス,
ブルース, エル. イニス,
チャールス, エイチ. ホーク,
サン ウェリントン,
カネサ−ササン ニラニャン,
Original Assignee
ウォルター リード アーミー インスティテュート オブ リサーチ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ウォルター リード アーミー インスティテュート オブ リサーチ filed Critical ウォルター リード アーミー インスティテュート オブ リサーチ
Publication of JP2002540168A publication Critical patent/JP2002540168A/ja
Publication of JP2002540168A5 publication Critical patent/JP2002540168A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24161Methods of inactivation or attenuation
    • C12N2770/24164Methods of inactivation or attenuation by serial passage
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000607657A 1999-03-26 2000-03-24 多価デングウイルスワクチン Pending JP2002540168A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12631399P 1999-03-26 1999-03-26
US18172400P 2000-02-11 2000-02-11
US60/181,724 2000-02-11
US60/126,313 2000-02-11
PCT/US2000/008199 WO2000057907A2 (en) 1999-03-26 2000-03-24 Multivalent dengue virus vaccine

Publications (2)

Publication Number Publication Date
JP2002540168A true JP2002540168A (ja) 2002-11-26
JP2002540168A5 JP2002540168A5 (https=) 2007-05-31

Family

ID=26824502

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000607657A Pending JP2002540168A (ja) 1999-03-26 2000-03-24 多価デングウイルスワクチン

Country Status (12)

Country Link
US (2) US6638514B1 (https=)
EP (1) EP1165127B1 (https=)
JP (1) JP2002540168A (https=)
KR (1) KR100721745B1 (https=)
CN (1) CN1191092C (https=)
AT (1) ATE419006T1 (https=)
AU (1) AU779280B2 (https=)
CA (1) CA2368674A1 (https=)
DE (1) DE60041250D1 (https=)
ES (1) ES2322327T3 (https=)
MX (1) MXPA01009683A (https=)
WO (1) WO2000057907A2 (https=)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008546382A (ja) * 2005-06-17 2008-12-25 サノフィ・パスツール デング熱セロタイプ1弱毒株
JP2009542783A (ja) * 2006-07-12 2009-12-03 サノフィ・パスツール 4種のデング熱血清型に対する免疫付与の方法
JP2010505801A (ja) * 2006-10-04 2010-02-25 サノフィ・パスツール 4種のデング血清型に対する免疫付与の方法
JP2010511022A (ja) * 2006-12-01 2010-04-08 サノフィ・パスツール デング熱の4種の血清型に対する免疫付与のプロトコル
JP2012513591A (ja) * 2008-12-22 2012-06-14 ザ チルドレンズ リサーチ インスティテュート 敗血症の検出のための方法
JP2012528794A (ja) * 2009-06-01 2012-11-15 インビラジェン, インコーポレイテッド デングウイルスに対するワクチンを投与するための組成物および方法
JP2013527759A (ja) * 2010-05-07 2013-07-04 ドイッチェス・クレープスフォルシュングスツェントルム ヒト神経膠腫を通して増殖及び伝播可能な改変齧歯類パルボウイルス
US9713638B2 (en) 2009-06-01 2017-07-25 Takeda Vaccines, Inc. Compositions and methods for rapid immunization against dengue virus
JP2020527540A (ja) * 2017-06-15 2020-09-10 プライムヴァックス イミュノ−オンコロジー,インク. デングウイルスならびに樹状細胞を用いた癌治療のための組成物および方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1165127B1 (en) * 1999-03-26 2008-12-31 Walter Reed Army Institute of Research Multivalent dengue virus vaccine
CA2966716C (en) 2001-05-22 2019-11-26 The Government Of The United States Of America, As Represented By The Cretary, Department Of Health And Human Services Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses
CA2611954C (en) * 2005-06-17 2014-01-28 Sanofi Pasteur Dengue serotype 2 attenuated strain
AR069087A1 (es) * 2007-10-29 2009-12-30 Boehringer Ingelheim Vetmed Cepa bacteriana de m. bovis atenuada avirulenta obtenida por pases, vacuna de micoplasma boris y metodos de uso de la misma
PE20110992A1 (es) 2009-02-17 2012-02-12 Glaxosmithkline Biolog Sa Composicion inmunogenica que comprende un antigeno del virus del dengue
JP2016523251A (ja) * 2013-06-21 2016-08-08 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. デングウイルスワクチン組成物およびその使用方法
ES2981476T3 (es) 2014-12-22 2024-10-09 Merck Sharp & Dohme Llc Composiciones de vacunas contra el virus del dengue y métodos de uso de las mismas
US9730989B2 (en) 2015-07-02 2017-08-15 PrimeVax Immuno-Oncology, Inc. Compositions and methods for combination therapy with dengue virus and dendritic cells
CA2999881A1 (en) 2015-09-26 2017-03-30 PrimeVax Immuno-Oncology, Inc. Compositions and methods for producing dendritic cells
BE1024160B9 (fr) 2015-12-22 2017-12-06 Glaxosmithkline Biologicals Sa Formulation immunogène
CN105777877B (zh) * 2016-04-05 2019-03-12 首都医科大学 登革病毒e蛋白阻断肽p4及其应用
CN105801674B (zh) * 2016-04-05 2019-03-12 首都医科大学 登革病毒e蛋白阻断肽p7及其应用
JP2020500847A (ja) 2016-11-16 2020-01-16 プライムヴァックス イミュノ−オンコロジー,インク. 癌の処置のための併用免疫療法
EP3565567A4 (en) 2017-01-04 2020-07-29 Primevax Immuno-Oncology, Inc. COMPOSITIONS AND METHODS OF THERAPY WITH DENGUE VIRUS
WO2018165373A1 (en) * 2017-03-08 2018-09-13 University Of Georgia Research Foundation, Inc. Methods and compositions related to increased viral production

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06181792A (ja) * 1992-06-05 1994-07-05 Nippon Zeon Co Ltd フラビウイルス科に属するウイルスの表面抗原タンパク質を含む非感染性の構造物粒子の製造方法、およびそれに用いる組み換えウイルス
WO1998018324A1 (en) * 1996-10-28 1998-05-07 The University Of Washington Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral rna

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69426077T3 (de) 1993-05-25 2004-09-02 Wyeth Holdings Corp. Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus
WO1996040933A1 (en) * 1995-06-07 1996-12-19 The Government Of The United States Of America, Represented By The Secretary Department Of Health And Human Services Infectious dengue 2 virus pdk-53 as quadravalent vaccine
EP1165127B1 (en) * 1999-03-26 2008-12-31 Walter Reed Army Institute of Research Multivalent dengue virus vaccine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06181792A (ja) * 1992-06-05 1994-07-05 Nippon Zeon Co Ltd フラビウイルス科に属するウイルスの表面抗原タンパク質を含む非感染性の構造物粒子の製造方法、およびそれに用いる組み換えウイルス
WO1998018324A1 (en) * 1996-10-28 1998-05-07 The University Of Washington Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral rna

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008546382A (ja) * 2005-06-17 2008-12-25 サノフィ・パスツール デング熱セロタイプ1弱毒株
JP2009542783A (ja) * 2006-07-12 2009-12-03 サノフィ・パスツール 4種のデング熱血清型に対する免疫付与の方法
JP2010505801A (ja) * 2006-10-04 2010-02-25 サノフィ・パスツール 4種のデング血清型に対する免疫付与の方法
JP2010511022A (ja) * 2006-12-01 2010-04-08 サノフィ・パスツール デング熱の4種の血清型に対する免疫付与のプロトコル
JP2012513591A (ja) * 2008-12-22 2012-06-14 ザ チルドレンズ リサーチ インスティテュート 敗血症の検出のための方法
JP2012528794A (ja) * 2009-06-01 2012-11-15 インビラジェン, インコーポレイテッド デングウイルスに対するワクチンを投与するための組成物および方法
JP2016033151A (ja) * 2009-06-01 2016-03-10 タケダ ワクチン, インコーポレイテッドTakeda Vaccines, Inc. デングウイルスに対する免疫原性組成物
US9713638B2 (en) 2009-06-01 2017-07-25 Takeda Vaccines, Inc. Compositions and methods for rapid immunization against dengue virus
US10010600B2 (en) 2009-06-01 2018-07-03 Takeda Vaccines, Inc. Compositions and methods for administration of vaccines against dengue virus
JP2013527759A (ja) * 2010-05-07 2013-07-04 ドイッチェス・クレープスフォルシュングスツェントルム ヒト神経膠腫を通して増殖及び伝播可能な改変齧歯類パルボウイルス
JP2020527540A (ja) * 2017-06-15 2020-09-10 プライムヴァックス イミュノ−オンコロジー,インク. デングウイルスならびに樹状細胞を用いた癌治療のための組成物および方法

Also Published As

Publication number Publication date
DE60041250D1 (de) 2009-02-12
US7217418B2 (en) 2007-05-15
WO2000057907A9 (en) 2002-04-11
KR20020008136A (ko) 2002-01-29
ES2322327T3 (es) 2009-06-19
CN1351502A (zh) 2002-05-29
CA2368674A1 (en) 2000-10-05
MXPA01009683A (es) 2003-06-24
US20070087015A1 (en) 2007-04-19
US6638514B1 (en) 2003-10-28
WO2000057907A2 (en) 2000-10-05
KR100721745B1 (ko) 2007-05-25
ATE419006T1 (de) 2009-01-15
AU779280B2 (en) 2005-01-13
CN1191092C (zh) 2005-03-02
AU4038200A (en) 2000-10-16
EP1165127B1 (en) 2008-12-31
WO2000057907A3 (en) 2001-04-12
EP1165127A2 (en) 2002-01-02

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