JP2002538775A - 骨刺激因子 - Google Patents

骨刺激因子

Info

Publication number
JP2002538775A
JP2002538775A JP2000593635A JP2000593635A JP2002538775A JP 2002538775 A JP2002538775 A JP 2002538775A JP 2000593635 A JP2000593635 A JP 2000593635A JP 2000593635 A JP2000593635 A JP 2000593635A JP 2002538775 A JP2002538775 A JP 2002538775A
Authority
JP
Japan
Prior art keywords
polypeptide
seq
amino acid
acid sequence
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000593635A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002538775A5 (OSRAM
Inventor
チャーク シン タム
Original Assignee
オステオファーム インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オステオファーム インコーポレイテッド filed Critical オステオファーム インコーポレイテッド
Publication of JP2002538775A publication Critical patent/JP2002538775A/ja
Publication of JP2002538775A5 publication Critical patent/JP2002538775A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2000593635A 1999-01-13 2000-01-13 骨刺激因子 Pending JP2002538775A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/229,304 1999-01-13
US09/229,304 US6693081B2 (en) 1995-09-26 1999-01-13 Bone stimulating factor
PCT/CA2000/000031 WO2000042069A1 (en) 1999-01-13 2000-01-13 Bone stimulating factor

Publications (2)

Publication Number Publication Date
JP2002538775A true JP2002538775A (ja) 2002-11-19
JP2002538775A5 JP2002538775A5 (OSRAM) 2007-03-01

Family

ID=22860649

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000593635A Pending JP2002538775A (ja) 1999-01-13 2000-01-13 骨刺激因子

Country Status (19)

Country Link
US (2) US6693081B2 (OSRAM)
EP (1) EP1161450A1 (OSRAM)
JP (1) JP2002538775A (OSRAM)
KR (1) KR20010101425A (OSRAM)
CN (1) CN1341120A (OSRAM)
AU (1) AU779261B2 (OSRAM)
BG (1) BG105682A (OSRAM)
BR (1) BR0007816A (OSRAM)
CA (1) CA2358908A1 (OSRAM)
CZ (1) CZ20012456A3 (OSRAM)
HU (1) HUP0105004A2 (OSRAM)
IL (1) IL143990A0 (OSRAM)
IS (1) IS5999A (OSRAM)
MA (1) MA25594A1 (OSRAM)
MX (1) MXPA01007043A (OSRAM)
NO (1) NO20013257L (OSRAM)
NZ (1) NZ512637A (OSRAM)
PL (1) PL349786A1 (OSRAM)
WO (1) WO2000042069A1 (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor
AU5379200A (en) * 1999-06-02 2000-12-28 Osteopharm Inc. Bone stimulating factor
CN100414265C (zh) * 2002-07-05 2008-08-27 加斯帕尔多塞米纳特里奇有限公司 用于定量输送颗粒状和粉末状材料、特别是用于分配所述材料的机器的体积计量装置
US7399826B1 (en) 2003-10-02 2008-07-15 Ali Sadat M Peptide for promoting healing of fractures
EP2718728A1 (en) * 2011-06-10 2014-04-16 Université Libre de Bruxelles Targets and agents for the treatment of impaired bone fracture healing
CN103159762B (zh) * 2013-03-25 2015-04-15 华东理工大学 表吲哚二酮衍生物及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08508158A (ja) * 1993-03-12 1996-09-03 オステオファーム リミテッド 骨刺激因子
WO1997012036A2 (en) * 1995-09-26 1997-04-03 Gensci Regeneration Sciences Inc. Bone stimulating factor
JPH09512253A (ja) * 1994-04-18 1997-12-09 オステオファーム リミテッド ヒトの骨刺激因子

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320118A (en) 1980-12-22 1982-03-16 Syntex (U.S.A.) Inc. Deca-, undeca-, dodeca- and tridecapeptides with thymic activity
US4897348A (en) 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
US4877864A (en) 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
US5354557A (en) 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US5024841A (en) 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US4950483A (en) 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5264214A (en) 1988-11-21 1993-11-23 Collagen Corporation Composition for bone repair
CH681625A5 (OSRAM) * 1988-12-08 1993-04-30 Sandoz Ag
US5461034A (en) 1989-02-23 1995-10-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenic growth polypeptides identified from regenerating bone marrow
WO1991011515A2 (en) 1990-02-01 1991-08-08 University Of South Florida Leukocyte-derived growth factor
CA2040264A1 (en) 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
ATE176239T1 (de) 1990-11-21 1999-02-15 Iterex Pharma Lp Synthese äquimolarer mischungen vielzähliger oligomere, speziell oligopeptidmischungen
ATE164167T1 (de) * 1990-12-21 1998-04-15 Curative Tech Inc Angiogene peptide
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
US5208219A (en) 1991-02-14 1993-05-04 Celtrix Pharmaceuticals Inc. Method for inducing bone growth
ATE139700T1 (de) 1991-02-15 1996-07-15 Takeda Chemical Industries Ltd Mit einem zellwachstumsfaktor bewirkte anregung von wachstum im knocheninneren
EP0504938A3 (en) 1991-03-22 1993-04-14 Suntory Limited Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
US5792664A (en) 1992-05-29 1998-08-11 The Rockefeller University Methods for producing and analyzing biopolymer ladders
ATE225801T1 (de) * 1992-07-13 2002-10-15 Bionebraska Inc Verfahren zur modifizierung rekombinanter polypeptide
US5304542A (en) 1992-08-28 1994-04-19 University Of Louisville Research Foundation, Inc. Use of platelet factor 4 to inhibit osteoblast proliferation
US5786327A (en) 1993-03-12 1998-07-28 Gensci Regeneration Sciences Inc. Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same
US5661127A (en) 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US5880094A (en) 1995-06-07 1999-03-09 Osteopharm Limited Polypeptides that stimulate bone growth
US6117839A (en) 1995-06-07 2000-09-12 Gensci Regeneration Sciences, Inc. Bone stimulating factor
US6352973B1 (en) 1995-06-07 2002-03-05 Osteopharm Inc. Bone stimulating factor
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08508158A (ja) * 1993-03-12 1996-09-03 オステオファーム リミテッド 骨刺激因子
JPH09512253A (ja) * 1994-04-18 1997-12-09 オステオファーム リミテッド ヒトの骨刺激因子
WO1997012036A2 (en) * 1995-09-26 1997-04-03 Gensci Regeneration Sciences Inc. Bone stimulating factor

Also Published As

Publication number Publication date
CN1341120A (zh) 2002-03-20
US20040147450A1 (en) 2004-07-29
CZ20012456A3 (cs) 2002-02-13
MA25594A1 (fr) 2002-12-31
AU3028200A (en) 2000-08-01
BG105682A (en) 2003-04-30
NZ512637A (en) 2003-08-29
US6693081B2 (en) 2004-02-17
AU779261B2 (en) 2005-01-13
HUP0105004A2 (hu) 2002-04-29
KR20010101425A (ko) 2001-11-14
BR0007816A (pt) 2002-12-31
WO2000042069A1 (en) 2000-07-20
EP1161450A1 (en) 2001-12-12
MXPA01007043A (es) 2002-03-27
CA2358908A1 (en) 2000-07-20
NO20013257D0 (no) 2001-06-29
IL143990A0 (en) 2002-04-21
PL349786A1 (en) 2002-09-09
NO20013257L (no) 2001-08-17
IS5999A (is) 2001-07-11
US20020090671A1 (en) 2002-07-11

Similar Documents

Publication Publication Date Title
JP4902352B2 (ja) トランスフォーミング増殖因子β1(TGF−β1)との結合能を有するペプチド
EP1100899A2 (en) Delta-related polypeptides
JP2002526073A (ja) 新規のヒト生長分化因子のコード配列、そのdna配列によりコードされるポリペプチド、およびこれらの製造方法。
JP2002524039A (ja) ヒトアポプトシス阻害剤タンパク質hiap3をコードするdna
AU2003255505B2 (en) Antagonists of CXR3-binding CXC chemokines
AU2002358144B2 (en) Chemokine mutants acting as chemokine antagonists
US6743895B1 (en) Bone stimulating factor
JP2002538775A (ja) 骨刺激因子
JPH08510207A (ja) ウロキナーゼプラスミノーゲンアクチベーターフラグメント
US6117839A (en) Bone stimulating factor
JP2807474B2 (ja) Dnaおよびその用途
JP7196113B2 (ja) ペプチド系化合物、その応用及びそれを含む組成物
EP0853667A2 (en) Bone stimulating factor
WO1992014834A1 (en) Insulin-like growth factor binding protein
CA2375475C (en) Serine proteinase inhibitors
WO2000075185A1 (en) Bone stimulating factor
EP4545551A1 (en) Peptide inhibitor and use thereof
AU2003302753A1 (en) Novel fibrillin-like polypeptides
WO2007002534A2 (en) Thrombospondin-1 derived peptides and treatment methods
JPWO2003066089A1 (ja) メグシンリガンド
JP2003342296A (ja) メグシン活性阻害因子
JPH07278191A (ja) 新規ペプチドもしくは蛋白質及びそれを探索する方法
JPH06293660A (ja) 腫瘍壊死因子阻害活性を有する新規ペプチド
CA2507990A1 (en) Novel ifngamma-like polypeptides

Legal Events

Date Code Title Description
RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20050407

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070112

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070112

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20091021

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100317