JP2002538110A - 喘息用のフォルモテロールおよびモメタゾンフロエートの組合せ - Google Patents
喘息用のフォルモテロールおよびモメタゾンフロエートの組合せInfo
- Publication number
- JP2002538110A JP2002538110A JP2000602059A JP2000602059A JP2002538110A JP 2002538110 A JP2002538110 A JP 2002538110A JP 2000602059 A JP2000602059 A JP 2000602059A JP 2000602059 A JP2000602059 A JP 2000602059A JP 2002538110 A JP2002538110 A JP 2002538110A
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- inflammatory
- formoterol
- dispersion
- dry powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
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- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| GB9904919.9 | 1999-03-03 | ||
| GBGB9904919.9A GB9904919D0 (en) | 1999-03-03 | 1999-03-03 | Organic compounds |
| PCT/EP2000/001722 WO2000051591A1 (en) | 1999-03-03 | 2000-03-01 | Combinations of formoterol and mometasone furoate for asthma |
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| JP2009174025A Division JP5646828B2 (ja) | 1999-03-03 | 2009-07-27 | 喘息用のフォルモテロールおよびモメタゾンフロエートの組合せ |
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| JP2002538110A true JP2002538110A (ja) | 2002-11-12 |
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| JP2009174025A Expired - Lifetime JP5646828B2 (ja) | 1999-03-03 | 2009-07-27 | 喘息用のフォルモテロールおよびモメタゾンフロエートの組合せ |
| JP2013010543A Expired - Lifetime JP5663046B2 (ja) | 1999-03-03 | 2013-01-23 | 喘息用のフォルモテロールおよびモメタゾンフロエートの組合せ |
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| JP2009174025A Expired - Lifetime JP5646828B2 (ja) | 1999-03-03 | 2009-07-27 | 喘息用のフォルモテロールおよびモメタゾンフロエートの組合せ |
| JP2013010543A Expired - Lifetime JP5663046B2 (ja) | 1999-03-03 | 2013-01-23 | 喘息用のフォルモテロールおよびモメタゾンフロエートの組合せ |
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| EP (2) | EP1325765A1 (https=) |
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| AT (1) | ATE241970T1 (https=) |
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| BR (1) | BR0008699A (https=) |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007506768A (ja) * | 2003-09-26 | 2007-03-22 | シェーリング コーポレイション | 肺疾患処置 |
| JP2014522880A (ja) * | 2011-08-08 | 2014-09-08 | プロソニックス リミテッド | 製剤組成物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9616237D0 (en) | 1996-08-01 | 1996-09-11 | Norton Healthcare Ltd | Aerosol formulations |
| GB9904919D0 (en) * | 1999-03-03 | 1999-04-28 | Novartis Ag | Organic compounds |
| GB9928311D0 (en) * | 1999-11-30 | 2000-01-26 | Novartis Ag | Organic compounds |
| GB0009612D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Therapeutic formulations |
| GB0012260D0 (en) | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel composition |
| AU2001278115A1 (en) * | 2000-08-04 | 2002-02-18 | Longwood Pharmaceutical Research, Inc. | Formulations of mometasone and a bronchodilator for pulmonary administration |
| US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
| TWI324934B (en) * | 2001-08-28 | 2010-05-21 | Schering Corp | Pharmaceutical compositions for the treatment of asthma |
| EP3384931B1 (en) * | 2002-03-01 | 2019-07-24 | Chiesi Farmaceutici S.p.A. | Formoterol superfine formulation |
| GB0207906D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and mometasone aerosol formulations |
| DK1542904T3 (da) * | 2002-08-27 | 2008-04-21 | Schering Corp | Fremgangsmåde til fremstilling af formuleringer til en inhalator med målte doser |
| US20040043064A1 (en) * | 2002-08-29 | 2004-03-04 | Iorio Theodore L. | Dosage forms having reduced moisture transmission |
| SE527200C2 (sv) * | 2003-06-19 | 2006-01-17 | Microdrug Ag | Inhalatoranordning samt kombinerade doser av formaterol och fluticason |
| TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| GB0323684D0 (en) | 2003-10-09 | 2003-11-12 | Jagotec Ag | Improvements in or relating to organic compounds |
| KR20060106823A (ko) * | 2003-10-20 | 2006-10-12 | 쉐링 코포레이션 | 약제학적 에어로졸 조성물 |
| EP1680084A2 (en) * | 2003-10-21 | 2006-07-19 | Direct-Haler A/S | A multiple route medication for the treatment of rhinitis and asthma |
| EP2484382A1 (en) * | 2005-03-30 | 2012-08-08 | Schering Corporation | Medicament comprising a phosphodiesterase IV inhibitor in an inhalable form |
| US20070099883A1 (en) * | 2005-10-07 | 2007-05-03 | Cheryl Lynn Calis | Anhydrous mometasone furoate formulation |
| WO2007059620A1 (en) * | 2005-11-23 | 2007-05-31 | Feanny Stephen J | Method for administering formoterol using a nebulizer |
| US20080253970A1 (en) * | 2007-02-09 | 2008-10-16 | Schering Corporation | Stable Pharmaceutical Drug Products |
| US20080294720A1 (en) * | 2007-05-21 | 2008-11-27 | International Business Machines Corporation | Enhanced Online Collaboration System |
| US8898316B2 (en) * | 2007-05-30 | 2014-11-25 | International Business Machines Corporation | Enhanced online collaboration system for viewers of video presentations |
| US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| MX337126B (es) | 2009-05-29 | 2016-02-12 | Pearl Therapeutics Inc | Administracion respiratoria de agentes activos. |
| GB0918149D0 (en) | 2009-10-16 | 2009-12-02 | Jagotec Ag | Improved medicinal aerosol formulation |
| WO2011093815A2 (en) * | 2010-01-29 | 2011-08-04 | Mahmut Bilgic | Pharmaceutical compositions comprising formoterol and mometasone |
| US20130177651A1 (en) * | 2010-09-03 | 2013-07-11 | Pharmaterials Limited | Pharmaceutical Composition Suitable for Use in a Dry Powder Inhaler |
| CN102416179B (zh) | 2010-09-28 | 2014-05-07 | 益得生物科技股份有限公司 | 用于哮喘的吸入性复方组合物 |
| WO2014007771A2 (en) | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising muscarinic receptor antagonist |
| WO2014007772A2 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising glucose anhydrous |
| KR102391332B1 (ko) | 2013-03-15 | 2022-04-26 | 펄 테라퓨틱스 인코포레이티드 | 미립자 결정질 재료를 컨디셔닝하는 방법 및 시스템 |
| ITMI20130571A1 (it) * | 2013-04-10 | 2014-10-11 | Zambon Spa | Composizione farmaceutica contenente budesonide e formoterolo |
| US9427376B2 (en) * | 2013-10-10 | 2016-08-30 | Chiesi Farmaceutici S.P.A. | Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient |
| KR102449403B1 (ko) * | 2014-10-08 | 2022-09-29 | 잠본쏘시에떼퍼아찌오니 | 부데소니드 및 포르모테롤을 함유하는 약학 조성물 |
| GB2545025A (en) * | 2015-12-04 | 2017-06-07 | Mexichem Fluor Sa De Cv | Pharmaceutical composition |
| EP3556348B1 (en) | 2015-12-04 | 2021-02-03 | Mexichem Fluor S.A. de C.V. | Pharmaceutical composition |
| CN115813935A (zh) * | 2021-09-16 | 2023-03-21 | 上海上药信谊药厂有限公司 | 药物组合物、气雾剂及其制备方法和气雾剂产生系统 |
| CN116763797B (zh) * | 2022-03-09 | 2025-09-02 | 上海医药工业研究院有限公司 | 一种药物组合微球、其制备方法及其原料组合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL95590A (en) | 1989-09-08 | 1996-06-18 | Glaxo Group Ltd | Medicinal preparations containing Salmetrol and Pluticasone Propionate |
| SE9302777D0 (sv) * | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
| US5874063A (en) * | 1991-04-11 | 1999-02-23 | Astra Aktiebolag | Pharmaceutical formulation |
| ES2172510T3 (es) | 1991-12-18 | 2002-10-01 | Astrazeneca Ab | Nueva combinacion de formoterol y budesonida. |
| US6596260B1 (en) | 1993-08-27 | 2003-07-22 | Novartis Corporation | Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol |
| PE44995A1 (es) | 1994-01-27 | 1995-12-18 | Schering Corp | Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias |
| US5837699A (en) * | 1994-01-27 | 1998-11-17 | Schering Corporation | Use of mometasone furoate for treating upper airway passage diseases |
| EP0806940B1 (en) | 1994-12-22 | 2003-04-09 | AstraZeneca AB | Aerosol drug formulations |
| SE9700135D0 (sv) * | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
| AU718967B2 (en) * | 1997-02-05 | 2000-05-04 | Jagotec Ag | Medical aerosol formulations |
| DK0969816T3 (da) * | 1997-03-20 | 2005-03-14 | Schering Corp | Fremstilling af pulveragglomerater |
| EP1033991B1 (en) * | 1997-10-09 | 2002-04-17 | Schering Corporation | Mometasone furoate suspensions for nebulization |
| MY133181A (en) * | 1998-09-10 | 2007-10-31 | Schering Corp | Methods and compositions for treating sinusitis, otitis media and other related disorders using antihistamines |
| GB9904919D0 (en) * | 1999-03-03 | 1999-04-28 | Novartis Ag | Organic compounds |
| TWI324934B (en) * | 2001-08-28 | 2010-05-21 | Schering Corp | Pharmaceutical compositions for the treatment of asthma |
-
1999
- 1999-03-03 GB GBGB9904919.9A patent/GB9904919D0/en not_active Ceased
-
2000
- 2000-03-01 SK SK1230-2001A patent/SK286338B6/sk not_active IP Right Cessation
- 2000-03-01 DE DE60003160T patent/DE60003160T2/de not_active Expired - Lifetime
- 2000-03-01 WO PCT/EP2000/001722 patent/WO2000051591A1/en not_active Ceased
- 2000-03-01 IL IL14435100A patent/IL144351A/en not_active IP Right Cessation
- 2000-03-01 CZ CZ20013168A patent/CZ294089B6/cs not_active IP Right Cessation
- 2000-03-01 CN CNB008041911A patent/CN1196478C/zh not_active Expired - Lifetime
- 2000-03-01 RU RU2001126347/63A patent/RU2270670C2/ru active
- 2000-03-01 ES ES00910739T patent/ES2200837T3/es not_active Expired - Lifetime
- 2000-03-01 PL PL349566A patent/PL212355B1/pl unknown
- 2000-03-01 AU AU32843/00A patent/AU770739B2/en not_active Expired
- 2000-03-01 ID IDW00200101780A patent/ID30171A/id unknown
- 2000-03-01 AT AT00910739T patent/ATE241970T1/de active
- 2000-03-01 HU HU0200142A patent/HU229073B1/hu unknown
- 2000-03-01 PT PT00910739T patent/PT1156790E/pt unknown
- 2000-03-01 NZ NZ513742A patent/NZ513742A/en not_active IP Right Cessation
- 2000-03-01 EP EP03003950A patent/EP1325765A1/en not_active Withdrawn
- 2000-03-01 KR KR1020017011162A patent/KR100682418B1/ko not_active Expired - Lifetime
- 2000-03-01 CA CA002362499A patent/CA2362499C/en not_active Expired - Lifetime
- 2000-03-01 JP JP2000602059A patent/JP2002538110A/ja not_active Withdrawn
- 2000-03-01 HK HK02103183.9A patent/HK1043048B/en unknown
- 2000-03-01 DK DK00910739T patent/DK1156790T3/da active
- 2000-03-01 BR BR0008699-1A patent/BR0008699A/pt not_active Application Discontinuation
- 2000-03-01 EP EP00910739A patent/EP1156790B1/en not_active Expired - Lifetime
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2001
- 2001-08-06 ZA ZA200106442A patent/ZA200106442B/en unknown
- 2001-08-16 NO NO20013988A patent/NO331428B1/no not_active IP Right Cessation
- 2001-08-30 US US09/942,805 patent/US20020055494A1/en not_active Abandoned
-
2002
- 2002-10-01 US US10/262,408 patent/US20030050290A1/en not_active Abandoned
-
2003
- 2003-11-20 US US10/718,316 patent/US7067502B2/en not_active Expired - Lifetime
-
2004
- 2004-05-20 CL CL200401170A patent/CL2004001170A1/es unknown
-
2005
- 2005-08-08 US US11/199,291 patent/US7566705B2/en not_active Expired - Fee Related
-
2009
- 2009-07-27 JP JP2009174025A patent/JP5646828B2/ja not_active Expired - Lifetime
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2013
- 2013-01-23 JP JP2013010543A patent/JP5663046B2/ja not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007506768A (ja) * | 2003-09-26 | 2007-03-22 | シェーリング コーポレイション | 肺疾患処置 |
| JP2014522880A (ja) * | 2011-08-08 | 2014-09-08 | プロソニックス リミテッド | 製剤組成物 |
| US9220708B2 (en) | 2011-08-08 | 2015-12-29 | Prosonix Limited | Pharmaceutical compositions |
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