JP2002537579A - 組織検体ホルダ - Google Patents
組織検体ホルダInfo
- Publication number
- JP2002537579A JP2002537579A JP2000600130A JP2000600130A JP2002537579A JP 2002537579 A JP2002537579 A JP 2002537579A JP 2000600130 A JP2000600130 A JP 2000600130A JP 2000600130 A JP2000600130 A JP 2000600130A JP 2002537579 A JP2002537579 A JP 2002537579A
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- tray
- specimen
- bag
- refractive index
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 claims abstract description 38
- 238000012545 processing Methods 0.000 claims abstract description 28
- 238000003384 imaging method Methods 0.000 claims abstract description 12
- 230000003287 optical effect Effects 0.000 claims description 31
- 238000007654 immersion Methods 0.000 claims description 24
- 230000008878 coupling Effects 0.000 claims description 21
- 238000010168 coupling process Methods 0.000 claims description 21
- 238000005859 coupling reaction Methods 0.000 claims description 21
- 239000000758 substrate Substances 0.000 claims description 11
- 239000012530 fluid Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 4
- 230000000087 stabilizing effect Effects 0.000 claims description 4
- 238000012014 optical coherence tomography Methods 0.000 claims description 2
- 238000005286 illumination Methods 0.000 claims 1
- 238000001574 biopsy Methods 0.000 abstract description 2
- 238000010226 confocal imaging Methods 0.000 abstract description 2
- 230000004075 alteration Effects 0.000 description 14
- 230000007246 mechanism Effects 0.000 description 14
- 239000012528 membrane Substances 0.000 description 7
- 239000012491 analyte Substances 0.000 description 6
- 239000004744 fabric Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 238000004026 adhesive bonding Methods 0.000 description 2
- 239000006059 cover glass Substances 0.000 description 2
- -1 for example Polymers 0.000 description 2
- 230000004927 fusion Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 238000001000 micrograph Methods 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0672—Integrated piercing tool
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0822—Slides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
- B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0339—Holders for solids, powders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0342—Solid sample being immersed, e.g. equiindex fluid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0364—Cuvette constructions flexible, compressible
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Ophthalmology & Optometry (AREA)
- Radiology & Medical Imaging (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microscoopes, Condenser (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12047099P | 1999-02-17 | 1999-02-17 | |
| US60/120,470 | 1999-02-17 | ||
| PCT/US2000/004128 WO2000049447A1 (en) | 1999-02-17 | 2000-02-17 | Tissue specimen holder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002537579A true JP2002537579A (ja) | 2002-11-05 |
| JP2002537579A5 JP2002537579A5 (enExample) | 2007-04-05 |
Family
ID=22390502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000600130A Pending JP2002537579A (ja) | 1999-02-17 | 2000-02-17 | 組織検体ホルダ |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6330106B1 (enExample) |
| EP (1) | EP1161702B1 (enExample) |
| JP (1) | JP2002537579A (enExample) |
| AU (1) | AU2882800A (enExample) |
| ES (1) | ES2520140T3 (enExample) |
| WO (1) | WO2000049447A1 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006030583A (ja) * | 2004-07-15 | 2006-02-02 | Olympus Corp | ペトリディッシュ、チャンバー装置、光学顕微鏡観察方法及び試料分析方法 |
| JP2016130673A (ja) * | 2015-01-14 | 2016-07-21 | オリンパス株式会社 | 顕微鏡観察用試料保持容器 |
| JP2017173293A (ja) * | 2016-03-21 | 2017-09-28 | 中国医科大学附属第一医院 | 低温組織試料包埋貯蔵システム |
| JP2018032009A (ja) * | 2016-08-18 | 2018-03-01 | オリンパス株式会社 | 顕微鏡 |
| JP2019511736A (ja) * | 2016-02-12 | 2019-04-25 | マサチューセッツ インスティテュート オブ テクノロジー | 切断されていない組織検体を撮像するための方法及び装置 |
| JP2020086044A (ja) * | 2018-11-21 | 2020-06-04 | オリンパス株式会社 | 倒立型顕微鏡 |
| US20210002688A1 (en) * | 2019-07-01 | 2021-01-07 | General Electric Company | Assessment of micro-organism presence |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7227630B1 (en) * | 1998-09-14 | 2007-06-05 | Lucid, Inc. | Imaging of surgical biopsies |
| WO2000015021A2 (en) * | 1998-09-14 | 2000-03-23 | Lucid, Inc. | Imaging of surgical biopsies |
| WO2000049447A1 (en) * | 1999-02-17 | 2000-08-24 | Lucid, Inc. | Tissue specimen holder |
| EP1169630B1 (en) | 1999-02-17 | 2017-02-01 | Lucid, Inc. | Cassette for facilitating optical sectioning of a retained tissue specimen |
| GB2360842B (en) * | 2000-03-31 | 2002-06-26 | Toshiba Res Europ Ltd | An apparatus and method for investigating a sample |
| US7194118B1 (en) | 2000-11-10 | 2007-03-20 | Lucid, Inc. | System for optically sectioning and mapping surgically excised tissue |
| WO2003041143A1 (en) * | 2001-11-09 | 2003-05-15 | Semiconductor Energy Laboratory Co., Ltd. | Laser beam treatment device and semiconductor device |
| US20070255169A1 (en) * | 2001-11-19 | 2007-11-01 | Dune Medical Devices Ltd. | Clean margin assessment tool |
| US20040133112A1 (en) * | 2002-03-08 | 2004-07-08 | Milind Rajadhyaksha | System and method for macroscopic and confocal imaging of tissue |
| US7197355B2 (en) * | 2002-04-19 | 2007-03-27 | Visiongate, Inc. | Variable-motion optical tomography of small objects |
| DE10239739B4 (de) * | 2002-08-29 | 2006-05-11 | Leica Mikrosysteme Gmbh | Vorrichtung und Verfahren zur Durchführung von immunologischen Markierungstechniken für Gewebedünnschnitte |
| WO2004070434A2 (en) * | 2003-02-04 | 2004-08-19 | Zetetic Institute | Compensation for effects of mismatch in indices of refraction at a substrate-medium interface in non-confocal, confocal, and interferometric confocal microscopy |
| US7026259B2 (en) * | 2004-01-21 | 2006-04-11 | International Business Machines Corporation | Liquid-filled balloons for immersion lithography |
| JP4587960B2 (ja) * | 2004-02-16 | 2010-11-24 | オリンパス株式会社 | 液浸対物レンズ及び液浸媒質の保持機構 |
| US7864996B2 (en) * | 2006-02-17 | 2011-01-04 | Lucid, Inc. | System for macroscopic and confocal imaging of tissue |
| US8260401B2 (en) | 2006-07-26 | 2012-09-04 | University Of Rochester | Non-invasive in-vivo imaging of mechanoreceptors in skin using confocal microscopy |
| US7973925B2 (en) * | 2007-02-06 | 2011-07-05 | C8 Medisensors Inc. | Apparatus for stabilizing mechanical, thermal, and optical properties and for reducing the fluorescence of biological samples for optical evaluation |
| US20090046359A1 (en) * | 2007-08-14 | 2009-02-19 | Nikon Corporation | Microscope |
| WO2009064380A2 (en) | 2007-11-09 | 2009-05-22 | California Institute Of Technology | Fabrication of anchored carbon nanotube array devices for integrated light collection and energy conversion |
| DE202008010411U1 (de) * | 2008-05-31 | 2008-10-16 | Klinika Medical Gmbh | Anordnung zum Transport und/oder zur Aufbewahrung einer menschlichen oder tierischen Gewebeprobe |
| WO2010021744A1 (en) * | 2008-08-21 | 2010-02-25 | California Institute Of Technology | Microscope coupled tissue sectioning system |
| EP2381972A2 (en) | 2009-01-27 | 2011-11-02 | California Institute Of Technology | Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface |
| US20140152801A1 (en) | 2009-10-28 | 2014-06-05 | Alentic Microscience Inc. | Detecting and Using Light Representative of a Sample |
| JP5638793B2 (ja) * | 2009-12-03 | 2014-12-10 | オリンパス株式会社 | 顕微鏡装置 |
| WO2011127207A2 (en) | 2010-04-07 | 2011-10-13 | California Institute Of Technology | Simple method for producing superhydrophobic carbon nanotube array |
| US8609458B2 (en) | 2010-12-10 | 2013-12-17 | California Institute Of Technology | Method for producing graphene oxide with tunable gap |
| WO2012135238A1 (en) | 2011-03-29 | 2012-10-04 | California Institute Of Technology | Method to increase the capacitance of electrochemical carbon nanotube capacitors by conformal deposition of nanoparticles |
| US8411265B2 (en) * | 2011-06-14 | 2013-04-02 | C8 Medisensors Inc. | Apparatus for stabilizing mechanical, thermal, and optical properties and for reducing the fluorescence of biological samples for optical evaluation |
| WO2013090844A1 (en) | 2011-12-14 | 2013-06-20 | California Institute Of Technology | Sharp tip carbon nanotube microneedle devices and their fabrication |
| ES3023614T3 (en) * | 2012-01-10 | 2025-06-02 | Uc Care Ltd | Device and method for handling biological tissues |
| ES2925001T3 (es) * | 2012-01-16 | 2022-10-13 | Mavig Gmbh | Método para preparar una muestra de tejido |
| ES2878548T3 (es) * | 2012-02-26 | 2021-11-19 | Caliber Imaging & Diagnostics Inc | Platina para muestras de tejido para un microscopio de seccionamiento óptico |
| US9349543B2 (en) | 2012-07-30 | 2016-05-24 | California Institute Of Technology | Nano tri-carbon composite systems and manufacture |
| US9677869B2 (en) | 2012-12-05 | 2017-06-13 | Perimeter Medical Imaging, Inc. | System and method for generating a wide-field OCT image of a portion of a sample |
| US10502666B2 (en) | 2013-02-06 | 2019-12-10 | Alentic Microscience Inc. | Sample processing improvements for quantitative microscopy |
| US9518920B2 (en) | 2013-06-26 | 2016-12-13 | Alentic Microscience Inc. | Sample processing improvements for microscopy |
| EP2801855B1 (en) | 2013-05-10 | 2019-07-17 | European Molecular Biology Laboratory | A microscope module for imaging a sample |
| AT16689U1 (de) * | 2013-05-10 | 2020-04-15 | European Molecular Biology Laboratory | Mikroskopmodul zum Abbilden einer Probe |
| DE102013210269B8 (de) | 2013-06-03 | 2015-01-29 | Laser Zentrum Hannover E.V. | Vorrichtung und Verfahren zur Untersuchung von Proben in einer Flüssigkeit |
| EP2873997A1 (de) * | 2013-11-15 | 2015-05-20 | Eppendorf Ag | Zählkammereinrichtung, Positioniereinrichtung für diese, Zählvorrichtung und Verfahren zur Zählung von mikroskopischen Partikeln |
| EP3139834B1 (en) | 2014-05-05 | 2022-03-16 | Caliber Imaging & Diagnostics, Inc. | System and method for mapping the locations of captured confocal images of a lesion in skin tissue |
| WO2016126861A1 (en) * | 2015-02-04 | 2016-08-11 | Apollo Medical Optics Inc. | Optical coherence tomography apparatus and its application |
| DE102015204134A1 (de) * | 2015-03-09 | 2016-09-15 | Carl Zeiss Microscopy Gmbh | Mikroskop zur sphärisch korrigierten Abbildung dreidimensionaler Objekte |
| GB201515961D0 (en) * | 2015-09-09 | 2015-10-21 | Secr Defence | A controlled atmosphere bag suitable for microscopy and spectroscopy |
| US10514532B1 (en) | 2015-09-27 | 2019-12-24 | Caliber Imaging & Diagnostics, Inc. | Confocal microscope having a positionable imaging head mounted on a boom stand |
| US11069054B2 (en) | 2015-12-30 | 2021-07-20 | Visiongate, Inc. | System and method for automated detection and monitoring of dysplasia and administration of immunotherapy and chemotherapy |
| US10935778B2 (en) | 2016-11-12 | 2021-03-02 | Caliber Imaging & Diagnostics, Inc. | Confocal microscope with positionable imaging head |
| DE102017105926A1 (de) * | 2017-03-20 | 2018-09-20 | Carl Zeiss Microscopy Gmbh | Verfahren und Mikroskop zum Abbilden eines Objektes |
| EP3655748B1 (en) * | 2017-07-18 | 2023-08-09 | Perimeter Medical Imaging, Inc. | Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis |
| WO2019051000A1 (en) * | 2017-09-05 | 2019-03-14 | Utah Valley University | COMPACT IMMERSION SCAN SYSTEM FOR HIGH FREQUENCY AUDIO WAVES |
| CN112136071B (zh) | 2018-02-26 | 2023-08-11 | 凯利博成像和诊断公司 | 用于对体外组织进行宏观和微观成像的系统和方法 |
| US11678658B2 (en) * | 2018-04-27 | 2023-06-20 | University Of North Texas Health Science Center | Devices, systems, and methods for modeling ocular translaminar pressure gradients |
| US10527528B2 (en) | 2018-05-22 | 2020-01-07 | Applikate Technologies Llc | Tissue chamber |
| DE102019215112A1 (de) * | 2019-10-01 | 2021-04-01 | Robert Bosch Gmbh | Vorrichtung zum Abschirmen eines Lichtwegs und Chiplabor-Analysegerät |
| CN111513772B (zh) * | 2020-03-30 | 2023-05-30 | 上海市浦东新区公利医院(第二军医大学附属公利医院) | 一种穿刺标本提取装置 |
| WO2021250013A1 (en) * | 2020-06-08 | 2021-12-16 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Optical pad and system employing the same |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3510194A (en) * | 1965-08-09 | 1970-05-05 | Robert F Connelly | Particle count membrane filter mount |
| DE2210442A1 (de) * | 1972-03-03 | 1973-09-06 | Remy Ernst Dr | Mikroskopanordnung zur untersuchung tiefgekuehlter proben, mit einer zwischen mikroskopobjektiv und probe bzw. probenabdeckung angeordneten immersionsfluessigkeit |
| JPS5353394A (en) * | 1976-10-21 | 1978-05-15 | Abbott Lab | Specimen holder |
| JPS56113115A (en) * | 1980-02-13 | 1981-09-05 | Mitsubishi Electric Corp | Sample table for immersion system microscope |
| DE3220702A1 (de) * | 1982-06-02 | 1983-12-08 | Manfred 7101 Eberstadt Fink | Spannvorrichtung fuer mikroskopisch zu untersuchende proben mit hintergrundneutralisierung |
| JPS643560A (en) * | 1987-05-29 | 1989-01-09 | Zeiss Carl Fa | Microinjection into cell or suction from individual cell or method and working station sucking all cells from cell incubation |
| JPH06245771A (ja) * | 1993-02-16 | 1994-09-06 | Perkin Elmer Corp:The | ターゲット核酸配列のインシトゥポリメラーゼ連鎖反応増幅用の封じ込めシステム、液体保持アセンブリ、核酸配列のインシトゥポリメラーゼ連鎖反応増幅用システム、アダプタープレート、及び該システムの組立装置 |
| JPH07140393A (ja) * | 1993-11-22 | 1995-06-02 | Ishikawajima Harima Heavy Ind Co Ltd | 顕微鏡用ガラス層厚み補正器 |
| JPH1039222A (ja) * | 1996-07-23 | 1998-02-13 | Nikon Corp | 顕微鏡 |
| JPH1039220A (ja) * | 1996-07-22 | 1998-02-13 | Nikon Corp | 顕微鏡 |
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| US568741A (en) * | 1896-10-06 | Henry r | ||
| US1002910A (en) * | 1911-01-21 | 1911-09-12 | Foote Mineral Co | Display-mount. |
| US1991983A (en) * | 1932-08-25 | 1935-02-19 | Joseph S Newman | Microscope slide |
| US3031924A (en) | 1959-03-12 | 1962-05-01 | James C Lamal | Observation slide |
| US3202049A (en) * | 1961-11-29 | 1965-08-24 | Bausch & Lomb | Liquid dispenser for microscope objective |
| DE1472294A1 (de) * | 1966-09-07 | 1969-02-13 | Leitz Ernst Gmbh | Immersionskoerper |
| GB1242527A (en) * | 1967-10-20 | 1971-08-11 | Kodak Ltd | Optical instruments |
| US3551023A (en) | 1969-01-17 | 1970-12-29 | Ibm | Pathology specimen processing method and article |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006030583A (ja) * | 2004-07-15 | 2006-02-02 | Olympus Corp | ペトリディッシュ、チャンバー装置、光学顕微鏡観察方法及び試料分析方法 |
| JP2016130673A (ja) * | 2015-01-14 | 2016-07-21 | オリンパス株式会社 | 顕微鏡観察用試料保持容器 |
| JP2019511736A (ja) * | 2016-02-12 | 2019-04-25 | マサチューセッツ インスティテュート オブ テクノロジー | 切断されていない組織検体を撮像するための方法及び装置 |
| JP2017173293A (ja) * | 2016-03-21 | 2017-09-28 | 中国医科大学附属第一医院 | 低温組織試料包埋貯蔵システム |
| JP2018032009A (ja) * | 2016-08-18 | 2018-03-01 | オリンパス株式会社 | 顕微鏡 |
| JP2020086044A (ja) * | 2018-11-21 | 2020-06-04 | オリンパス株式会社 | 倒立型顕微鏡 |
| JP7145051B2 (ja) | 2018-11-21 | 2022-09-30 | 株式会社エビデント | 倒立型顕微鏡 |
| US20210002688A1 (en) * | 2019-07-01 | 2021-01-07 | General Electric Company | Assessment of micro-organism presence |
| US11597960B2 (en) * | 2019-07-01 | 2023-03-07 | General Electric Company | Assessment of micro-organism presence |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000049447A1 (en) | 2000-08-24 |
| US20050157386A1 (en) | 2005-07-21 |
| ES2520140T3 (es) | 2014-11-11 |
| US6856458B2 (en) | 2005-02-15 |
| US20020101655A1 (en) | 2002-08-01 |
| US9128024B2 (en) | 2015-09-08 |
| EP1161702A1 (en) | 2001-12-12 |
| AU2882800A (en) | 2000-09-04 |
| EP1161702B1 (en) | 2014-07-23 |
| EP1161702A4 (en) | 2007-10-24 |
| US6330106B1 (en) | 2001-12-11 |
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