JP2002537340A5 - - Google Patents

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Publication number
JP2002537340A5
JP2002537340A5 JP2000600654A JP2000600654A JP2002537340A5 JP 2002537340 A5 JP2002537340 A5 JP 2002537340A5 JP 2000600654 A JP2000600654 A JP 2000600654A JP 2000600654 A JP2000600654 A JP 2000600654A JP 2002537340 A5 JP2002537340 A5 JP 2002537340A5
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JP
Japan
Prior art keywords
composition
syndrome
mitochondrial
deficiency
substituted
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Granted
Application number
JP2000600654A
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English (en)
Japanese (ja)
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JP2002537340A (ja
JP4776780B2 (ja
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Priority claimed from PCT/US2000/004663 external-priority patent/WO2000050043A1/en
Publication of JP2002537340A publication Critical patent/JP2002537340A/ja
Publication of JP2002537340A5 publication Critical patent/JP2002537340A5/ja
Application granted granted Critical
Publication of JP4776780B2 publication Critical patent/JP4776780B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2000600654A 1999-02-23 2000-02-23 ミトコンドリア病の治療方法 Expired - Lifetime JP4776780B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12158899P 1999-02-23 1999-02-23
US60/121,588 1999-02-23
PCT/US2000/004663 WO2000050043A1 (en) 1999-02-23 2000-02-23 Methods of treatment of mitochondrial disorders

Publications (3)

Publication Number Publication Date
JP2002537340A JP2002537340A (ja) 2002-11-05
JP2002537340A5 true JP2002537340A5 (enExample) 2007-04-12
JP4776780B2 JP4776780B2 (ja) 2011-09-21

Family

ID=22397641

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000600654A Expired - Lifetime JP4776780B2 (ja) 1999-02-23 2000-02-23 ミトコンドリア病の治療方法

Country Status (20)

Country Link
US (2) US7638501B1 (enExample)
EP (2) EP1171137B1 (enExample)
JP (1) JP4776780B2 (enExample)
KR (2) KR100879559B1 (enExample)
CN (2) CN1191835C (enExample)
AT (1) ATE381935T1 (enExample)
AU (1) AU776437B2 (enExample)
BR (1) BR0008447A (enExample)
CA (1) CA2362925C (enExample)
DE (1) DE60037578T2 (enExample)
DK (1) DK1171137T3 (enExample)
ES (1) ES2298130T3 (enExample)
HU (1) HU230191B1 (enExample)
IL (3) IL144964A0 (enExample)
MX (1) MXPA01008549A (enExample)
NZ (1) NZ513926A (enExample)
PT (1) PT1171137E (enExample)
RU (2) RU2268732C2 (enExample)
WO (1) WO2000050043A1 (enExample)
ZA (1) ZA200107727B (enExample)

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EP3827815B1 (en) 2008-09-10 2023-09-06 PTC Therapeutics, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
RU2400221C2 (ru) * 2008-11-11 2010-09-27 ФГУ "Московский НИИ педиатрии и детской хирургии Росмедтехнологий" Способ лечения врожденных структурных миопатий и врожденных мышечных дистрофий путем коррекции вторичных митохондриальных изменений
ES2640485T3 (es) * 2011-08-12 2017-11-03 Universitätsklinikum Freiburg Uridina y análogos de uridina para el uso en el tratamiento de la enfermedad pulmonar obstructiva crónica
WO2015106255A1 (en) 2014-01-13 2015-07-16 City Of Hope Multivalent oligonucleotide assemblies
DK3182980T3 (da) * 2014-08-19 2021-01-11 Wellstat Therapeutics Corp Behandling af glykosyleringsmangelsygdomme
FR3027804A1 (fr) * 2014-10-31 2016-05-06 Centre Nat Rech Scient Utilisation d'un inhibiteur de transcriptase inverse dans la prevention et le traitement des maladies degeneratives
BR112017022578A2 (pt) 2015-05-29 2018-07-17 The Board Of Trustees Of The Leland Stanford Junior University agentes nucleosídicos para a redução da atividade deletéria de genes que contém repetições estendidas de nucleotídeos
PL3302499T3 (pl) * 2015-06-05 2023-07-24 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Leczenie chorób mitochondrialnych
US10471087B2 (en) * 2015-06-17 2019-11-12 The Trustees Of Columbia University In The City Of New York Deoxynucleoside therapy for diseases caused by unbalanced nucleotide pools including mitochondrial DNA depletion syndromes
US10703701B2 (en) 2015-12-17 2020-07-07 Ptc Therapeutics, Inc. Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
KR101981843B1 (ko) 2016-09-13 2019-05-23 울산대학교 산학협력단 일산화탄소 또는 일산화탄소 공급체를 유효성분으로 함유하는 미토콘드리아 기능 개선용 조성물
AU2019242628A1 (en) 2018-03-26 2020-09-24 Clear Creek Bio, Inc. Compositions and methods for inhibiting dihydroorotate dehydrogenase
CN114340641B (zh) * 2019-09-05 2025-04-04 米托瑞因博治疗股份有限公司 治疗线粒体dna缺失障碍
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KR102290596B1 (ko) * 2020-09-10 2021-08-19 주식회사 파이안바이오테크놀로지 분리된 미토콘드리아를 포함하는 주사용 조성물 및 이의 용도
KR20230067613A (ko) * 2020-09-14 2023-05-16 웰스태트 테러퓨틱스 코포레이션 5' 위치에서 아세토아세틸로 치환된 2',3'-디아세틸우리딘
EP3970713A1 (en) 2020-09-16 2022-03-23 GV Squared S.r.l. Pharmaceutical composition comprising uridine and pyruvate for regulating the profileration, activity and survival of immune cells
CN113116900B (zh) * 2021-04-14 2022-07-08 兰州大学 一类核苷类似物在制备预防和/或治疗脑血管疾病药物中的应用
BE1030026B1 (fr) * 2022-06-14 2023-07-07 Dendrogenix Composés dérivés de stérols et composition pharmaceutique les comprenant pour leur utilisation dans la prévention, l’amélioration et/ou le traitement d’une pathologie liée à un déficit mitochondrial

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